Clinical Trials Updated in October 2025

NCT07223476 | COMPLETED

1926 participants

Treatment Landscape and Real-World Dosing Patterns With CDK4/6 Inhibitors for Breast Cancer in Portugal

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-03-29
Completion:: 2024-07-01

Conditions

Breast Cancer

No Results Yet

NCT07223359 | COMPLETED | NA

59 participants

Photographic Evidence on Total Knee Arthroplasty Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2020-01-01
Completion:: 2021-12-31

Conditions

Osteoarthritis (OA) of the Knee

Interventions

BEHAVIORAL

No Results Yet

NCT07223346 | RECRUITING | NA

20 participants

Latinas Integrating Fitness and Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-01
Completion:: 2026-12-31

Conditions

Stepped Care Cognitive Behavioral Therapy
Exercise
Physical Activity
Anxiety Depression

Interventions

BEHAVIORAL

No Results Yet

NCT07223268 | RECRUITING | NA

270 participants

Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-07
Completion:: 2030-08-31

Conditions

Diabetic Foot Ulcer

Interventions

OTHER

No Results Yet

NCT07223242 | RECRUITING | PHASE2/PHASE3

120 participants

Tailored Exercise Training Study Among Adults With HFpEF

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-02-18
Completion:: 2026-12-30

Conditions

HFpEF - Heart Failure With Preserved Ejection Fraction
Diabetic Cardiomyopathies

Interventions

BEHAVIORAL
DRUG

No Results Yet

NCT07223073 | COMPLETED | PHASE3

80 participants

A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothpaste

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2017-12-21
Completion:: 2018-01-12

Conditions

Oral Malodor

Interventions

DRUG

No Results Yet

NCT07222982 | RECRUITING | NA

54 participants

Social Groups for Autistic Young Adults (SDARIYA)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2026-01-15
Completion:: 2030-02-28

Conditions

Autism Spectrum Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07222618 | RECRUITING

300 participants

"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-01
Completion:: 2028-10-01

Conditions

Multiple Sclerosis
Multiple Sclerosis (MS) - Relapsing-remitting
Multiple Sclerosis (MS) Primary Progressive
MS (Multiple Sclerosis)
MS
Multiple Sclerosis (MS) Secondary Progressive

No Results Yet

NCT07203885 | COMPLETED | NA

10 participants

AI-Assisted Acute Myeloid Leukemia Evaluation With the Leukemia End-to-End Analysis Platform (LEAP) Versus Clinician-Only Assessment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-09-09
Completion:: 2025-10-10

Conditions

Acute Promyelocytic Leukemia (APL)
Acute Myeloid Leukaemia (AML)

Interventions

BEHAVIORAL

No Results Yet

NCT07164846 | RECRUITING | NA

30 participants

Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-08-05
Completion:: 2026-08-01

Conditions

Spinal Cord Injury
Stroke
Amputees

Interventions

DEVICE

No Results Yet

NCT07150832 | RECRUITING | NA

173 participants

Efficacy of the I-CARE Digital Health Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-06
Completion:: 2027-06-30

Conditions

Mental Health Disorder
Suicide Attempt
Suicidal Ideation
Emergency Psychiatric

Interventions

BEHAVIORAL

No Results Yet

NCT07137871 | RECRUITING | PHASE1

35 participants

Clinical Trial of Avasopasem in Patients With Metastatic Hormone Receptor Positive Breast Cancer With Progression on a CDK 4/6 Inhibitor and Hormonal Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-02
Completion:: 2027-10-31

Conditions

Breast Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT07131475 | RECRUITING | PHASE2

100 participants

Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-14
Completion:: 2029-04-30

Conditions

Blast Injury

Interventions

DRUG

No Results Yet

NCT07106125 | NOT_YET_RECRUITING | PHASE4

50 participants

Antibiotics for Kidney Transplant Recipients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2026-11-30
Completion:: 2028-12-31

Conditions

Kidney Transplant
Urinary Tract Infection(UTI)
Antibiotic Prophylaxis
Remote Patient Monitoring
Feasibility Pilot Study

Interventions

OTHER
DRUG

No Results Yet

NCT07096453 | RECRUITING | PHASE1/PHASE2

30 participants

CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-02
Completion:: 2027-08-31

Conditions

Kidney Transplant; Complications
CMV

Interventions

DRUG

No Results Yet

NCT07092774 | ACTIVE_NOT_RECRUITING

344 participants

Real-world Safety and Effectiveness Registry of Catheter Ablation of Paroxysmal Atrial Fibrillation as Initial Control Therapy With the Thermocool SmartTouch SF Catheter (A Sub-study of REAL AF Registry)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-04-01
Completion:: 2025-12-31

Conditions

Paroxysmal Atrial Fibrillation (PAF)

Interventions

DEVICE

No Results Yet

NCT06986122 | RECRUITING | NA

20 participants

Virtual Contexts for Affective Modulation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-28
Completion:: 2027-06-15

Conditions

Pain Control
Anxiety
Memory

Interventions

BEHAVIORAL

No Results Yet

NCT06960720 | RECRUITING | NA

60 participants

Lifting More Than Weights: Resistance Exercise Program Across Socioeconomic Groups for Cancer-Related Fatigue Management

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-10-13
Completion:: 2026-12-31

Conditions

Breast Cancer
Fatigue

Interventions

OTHER

No Results Yet

NCT06838325 | COMPLETED | NA

24 participants

The Effect of the Prostate Cancer Foundation Screening Guidelines for Black Men on Intention to Screen in Faith-based Communities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-02-06
Completion:: 2025-10-29

Conditions

Prostate Cancer Screening

Interventions

OTHER

No Results Yet

NCT06795867 | RECRUITING | NA

40 participants

Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-04-21
Completion:: 2027-12-31

Conditions

Chronic Migraine

Interventions

BEHAVIORAL

No Results Yet

NCT06686914 | RECRUITING | PHASE1

300 participants

The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-06-30
Completion:: 2028-12-31

Conditions

Cannabidiol Effects
Driving Performance

Interventions

DRUG

No Results Yet

NCT06653400 | RECRUITING | PHASE1

60 participants

Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-02-27
Completion:: 2026-09-01

Conditions

Abnormal Uterine Bleeding
Analgesia
Paracervical Block

Interventions

PROCEDURE
DRUG

No Results Yet

NCT06619054 | COMPLETED | PHASE1

24 participants

A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of KP-001

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-10-24
Completion:: 2025-05-16

Conditions

Healthy Adults
Hepatic Impairment

Interventions

DRUG

No Results Yet

NCT06562777 | RECRUITING

100 participants

Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2023-09-15
Completion:: 2026-03-01

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT06549790 | RECRUITING | PHASE1

124 participants

Study of NMS-03597812 in Adult Patients With Relapsed/Refractory Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-10-16
Completion:: 2029-09-15

Conditions

Relapsed/Refractory Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT06547268 | TERMINATED

2 participants

Advancing the Science of Pediatric Interstage Home Monitoring

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-07-24
Completion:: 2025-10-30

Conditions

Heart Defects, Congenital

Interventions

DEVICE

No Results Yet

NCT06513156 | RECRUITING | NA

304 participants

Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-10-01
Completion:: 2026-07-30

Conditions

Opioid Use Disorder
Injection Related Infections
Stimulant Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06501781 | RECRUITING | NA

186 participants

Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-03-18
Completion:: 2028-12-31

Conditions

HIV Infections
Substance Use

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06434558 | ENROLLING_BY_INVITATION

10 participants

Imaging Predictors of Cryolysis Efficacy for Treatment of Obstructive Sleep Apnea

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-06-12
Completion:: 2027-01-31

Conditions

Obstructive Sleep Apnea of Adult

Interventions

PROCEDURE

No Results Yet

NCT06396533 | RECRUITING

92 participants

Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-08-13
Completion:: 2027-04-23

Conditions

Urothelial Carcinoma
Muscle Invasive Bladder Urothelial Carcinoma
Non-Muscle Invasive Bladder Urothelial Carcinoma

No Results Yet

NCT06369753 | RECRUITING | NA

100 participants

Visible Abdominal Distension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2025-07-30
Completion:: 2026-04-30

Conditions

Irritable Bowel Syndrome
Dyspepsia
Functional Bloating

Interventions

BEHAVIORAL

No Results Yet

NCT06354777 | ACTIVE_NOT_RECRUITING

312 participants

REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-04-03
Completion:: 2026-04-30

Conditions

Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT06327815 | COMPLETED | PHASE4

633 participants

Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-03-15
Completion:: 2025-06-30

Conditions

Type 2 Diabetes Mellitus (T2DM)

Interventions

DRUG

No Results Yet

NCT06324201 | RECRUITING

250 participants

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-02-27
Completion:: 2026-03-31

Conditions

Paroxysmal Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT06308666 | COMPLETED | NA

41 participants

Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-03-18
Completion:: 2024-10-23

Conditions

Myopia

Interventions

DEVICE

Results Available

NCT06303778 | RECRUITING | NA

330 participants

Combining a Smartphone App With Medications to Manage Heavy Drinking

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-11-01
Completion:: 2028-11-01

Conditions

Alcohol Use Disorder (AUD)

Interventions

OTHER

No Results Yet

NCT06268288 | COMPLETED | NA

40 participants

Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-02-14
Completion:: 2024-10-05

Conditions

Postural Tachycardia Syndrome
Autonomic Dysfunction
Postural Orthostatic Tachycardia Syndrome
POTS - Postural Orthostatic Tachycardia Syndrome

Interventions

DEVICE
OTHER

Results Available

NCT06250751 | COMPLETED | NA

27 participants

Behavioral Exercise TRaining for Men Undergoing Androgen Depr Therapy for Prostate Ca

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-02-05
Completion:: 2025-10-06

Conditions

Prostate Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06215131 | COMPLETED | NA

20 participants

Feasibility of Immersive Virtual Reality Dietician Program in Metabolic-dysfunction Associated Steatotic Liver Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-07-01
Completion:: 2025-09-23

Conditions

Fatty Liver, Nonalcoholic
Weight Loss
Virtual Reality
Implementation Science

Interventions

BEHAVIORAL

No Results Yet

NCT06208748 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

Study Type:: INTERVENTIONAL
Last Updated:: 2025-10-31
Start Date:: 2024-08-01
Completion:: 2026-06-30

Conditions

Gastrointestinal Stromal Tumors
GIST

Interventions

DRUG

No Results Yet