Clinical Trials Updated in 2026

NCT06696443 | ACTIVE_NOT_RECRUITING | PHASE3

455 participants

Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants With Painful Diabetic Peripheral Neuropathy (DPN)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-12-18
Completion:: 2027-01-25

Conditions

Diabetic Peripheral Neuropathic Pain

Interventions

DRUG

No Results Yet

NCT06694480 | RECRUITING | PHASE1

24 participants

Study of FID-022 in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-07-03
Completion:: 2027-12-31

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT06692179 | COMPLETED | PHASE1

21 participants

An Open-Label, Pilot Clinical Trial To Test The Safety And Feasibility Of A Suspension of Freeze-dried Microbiota In Patients Undergoing Colon Resection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-02-18
Completion:: 2026-06-08

Conditions

Recurrent Clostridioides Difficile Infection
Colonic Surgery

Interventions

DRUG

No Results Yet

NCT06692049 | RECRUITING

250 participants

Gonadal Tissue Cryopreservation for Fertility Preservation in Children With a Disorder of Sex Development

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2018-04-04
Completion:: 2030-12-31

Conditions

DSD, 46,XY
DSD, Ovotesticular
DSD, Sex Chromosome
Disorders of Sex Development
Disorder of Sex Development, 46,XY
Disorder of Sex Development, 46,Xy, Cbx2-Related

Interventions

PROCEDURE

No Results Yet

NCT06690931 | COMPLETED | NA

30 participants

Neurofeedback Rehabilitation With FES and VR for PD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-12-09
Completion:: 2026-06-25

Conditions

Parkinson Disease

Interventions

DEVICE

No Results Yet

NCT06683742 | ACTIVE_NOT_RECRUITING | PHASE3

400 participants

A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-11-27
Completion:: 2026-10-31

Conditions

Wet Age Related Macular Degeneration
wAMD

Interventions

DRUG

No Results Yet

NCT06676566 | ENROLLING_BY_INVITATION

600 participants

Information, Follow-up and Early Diagnosis of Children at Risk for Type 1 Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-14
Completion:: 2034-10-01

Conditions

Type 1 Diabetes Mellitus
Stage 2 Type 1 Diabetes
Stage 1 Type 1 Diabetes
Stage 3 Type 1 Diabetes

No Results Yet

NCT06670651 | ENROLLING_BY_INVITATION

600 participants

LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-03-21
Completion:: 2031-12-31

Conditions

Osteoarthritis (OA) of the Knee
Fracture
Rheumatoid Arthritis

Interventions

DEVICE

No Results Yet

NCT06668493 | RECRUITING | PHASE1/PHASE2

20 participants

Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-06-12
Completion:: 2029-11-30

Conditions

Low-grade Upper Tract Urothelial Carcinoma

Interventions

DRUG

No Results Yet

NCT06668064 | ACTIVE_NOT_RECRUITING | PHASE3

400 participants

A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-22
Completion:: 2026-07-13

Conditions

Wet Age Related Macular Degeneration
wAMD

Interventions

DRUG

No Results Yet

NCT06665412 | ACTIVE_NOT_RECRUITING

169 participants

Efficacy and Safety of Dose Redution of Radotinib as a First Line Treament in Ph+ CML

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-24
Completion:: 2027-07-15

Conditions

Chronic Phase Ph+ Chronic Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT06662188 | RECRUITING | PHASE1/PHASE2

6 participants

JAG201 Gene Therapy Study in Children & Adults With SHANK3 Haploinsufficiency

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-01-07
Completion:: 2028-06-30

Conditions

SHANK3 Haploinsufficiency
Phelan-McDermid Syndrome

Interventions

GENETIC

No Results Yet

NCT06659081 | ACTIVE_NOT_RECRUITING | NA

14 participants

Effect of Subepithelial Connective Tissue Graft With Socket Shield Technique

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-12-04
Completion:: 2025-06-01

Conditions

Socket Shield Technique Implant Placement
Immediate Implant Placement

Interventions

PROCEDURE

No Results Yet

NCT06649812 | RECRUITING | PHASE2

120 participants

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-10-07
Completion:: 2028-09-01

Conditions

High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements
Recurrent Diffuse Large B-Cell Lymphoma
Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified
Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified
Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT06649331 | RECRUITING | PHASE2

160 participants

Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-21
Completion:: 2026-09-30

Conditions

Advanced Breast Cancer
Metastatic Breast Cancer
Triple Negative Breast Cancer (TNBC)
HER2-negative Breast Cancer
Breast Cancer

Interventions

DRUG
DIETARY_SUPPLEMENT

No Results Yet

NCT06646237 | RECRUITING

350 participants

Diagnostic Utility of Mycobacterium Tuberculosis Cell-free DNA in Hong Kong

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2026-01-01
Completion:: 2027-06-30

Conditions

Tuberculosis, Pleural
Pleural Biopsy

No Results Yet

NCT06635980 | RECRUITING | PHASE2

120 participants

Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-05-14
Completion:: 2031-10-21

Conditions

Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Breast Carcinoma
Triple-Negative Breast Carcinoma

Interventions

PROCEDURE
DRUG
RADIATION
OTHER

No Results Yet

NCT06632457 | RECRUITING | PHASE3

1590 participants

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-11-12
Completion:: 2029-06-05

Conditions

Metabolic Dysfunction Associated Steatohepatitis

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06618157 | ENROLLING_BY_INVITATION | NA

20 participants

Connectomic Guided DBS for Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2026-02-16
Completion:: 2026-12-29

Conditions

Parkinson Disease
Tremor
Dyskinesias

Interventions

DEVICE
OTHER

No Results Yet

NCT06617169 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-08
Completion:: 2027-01-31

Conditions

Solid Tumor, Adult
Bladder Cancer
Urothelial Carcinoma
Triple-negative Breast Cancer
Lung Cancer
Colorectal Cancer
Gastric Cancer
Ovarian Cancer
Pancreatic Cancer

Interventions

DRUG

No Results Yet

NCT06600789 | RECRUITING | PHASE1/PHASE2

50 participants

A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-08-16
Completion:: 2027-03-14

Conditions

Solid Malignancies

Interventions

DRUG

No Results Yet

NCT06596291 | RECRUITING | PHASE1/PHASE2

16 participants

Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-01-08
Completion:: 2027-06-30

Conditions

Neurogenic Detrusor Overactivity
Spinal Cord Injuries

Interventions

DRUG

No Results Yet

NCT06589804 | RECRUITING | PHASE3

158 participants

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-03-27
Completion:: 2029-11-30

Conditions

Metastatic Head and Neck Squamous Cell Carcinoma
Metastatic Hypopharyngeal Squamous Cell Carcinoma
Metastatic Laryngeal Squamous Cell Carcinoma
Metastatic Oral Cavity Squamous Cell Carcinoma
Metastatic Oropharyngeal Squamous Cell Carcinoma
Recurrent Head and Neck Squamous Cell Carcinoma
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Oral Cavity Squamous Cell Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Refractory Head and Neck Squamous Cell Carcinoma
Refractory Hypopharyngeal Squamous Cell Carcinoma
Refractory Laryngeal Squamous Cell Carcinoma
Refractory Oral Cavity Squamous Cell Carcinoma
Refractory Oropharyngeal Squamous Cell Carcinoma
Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
Stage IV Hypopharyngeal Carcinoma AJCC v8
Stage IV Laryngeal Cancer AJCC v8
Stage IV Lip and Oral Cavity Cancer AJCC v8
Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT06587230 | RECRUITING | NA

312 participants

Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-08
Completion:: 2026-10-31

Conditions

Child Behavior
Mental Health Issue
Psychosocial Functioning
Depression
Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT06567743 | RECRUITING | PHASE2

325 participants

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-09-16
Completion:: 2027-03-31

Conditions

High-Risk Non-Muscle-Invasive Bladder Cancer

Interventions

DRUG

No Results Yet

NCT06563167 | ACTIVE_NOT_RECRUITING

330 participants

Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-09-01
Completion:: 2026-12-31

Conditions

Lung Biopsy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06560398 | RECRUITING | NA

7649 participants

Working Through Outreach, Navigation and Digital Enabled Referral and Recruitment Strategies (ACT WONDER²S)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-09-18
Completion:: 2026-09-16

Conditions

Cancer

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06557707 | RECRUITING

120 participants

Cardiovascular Health & Early Stress

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-01-20
Completion:: 2027-12-31

Conditions

Stress

Interventions

OTHER

No Results Yet

NCT06555419 | RECRUITING | PHASE1

78 participants

A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-01-16
Completion:: 2027-09-30

Conditions

Muscular Atrophy, Spinal

Interventions

DRUG
DEVICE

No Results Yet

NCT06554327 | RECRUITING | NA

265 participants

Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-03-06
Completion:: 2030-09-06

Conditions

Ventilator Associated Pneumonia

Interventions

DEVICE

No Results Yet

NCT06545877 | COMPLETED

571 participants

REKOVELLE PEN for S.C. Injection General Drug Use Survey (Controlled Ovarian Stimulation in Assisted Reproductive Technologies)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-09-16
Completion:: 2025-04-30

Conditions

Infertility

No Results Yet

NCT06541262 | RECRUITING | PHASE1/PHASE2

104 participants

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-30
Completion:: 2030-11-01

Conditions

Neuroblastoma
Ewing Sarcoma
Osteosarcoma
Rhabdomyosarcoma
Liposarcoma

Interventions

DRUG

No Results Yet

NCT06540963 | RECRUITING | PHASE2

98 participants

Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-12-06
Completion:: 2030-12-01

Conditions

Neuroblastoma

Interventions

DRUG

No Results Yet

NCT06538870 | RECRUITING | NA

30 participants

Dental Implant Healing With TNF-Alpha Inhibitors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-06-28
Completion:: 2026-12-31

Conditions

Edentulism
Dental Implants
TNF-alpha Inhibitors

Interventions

PROCEDURE

No Results Yet

NCT06535516 | RECRUITING | NA

60 participants

Resilient Roots: Supporting Youth and Families

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-15
Completion:: 2027-08-01

Conditions

Posttraumatic Stress Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06524414 | ACTIVE_NOT_RECRUITING | PHASE2

605 participants

A Study to Learn About How a New Pneumococcal Vaccine Works in Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-25
Completion:: 2027-05-01

Conditions

Pneumococcal Disease

Interventions

BIOLOGICAL

No Results Yet

NCT06515613 | RECRUITING | PHASE1

156 participants

A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-10
Completion:: 2028-05-31

Conditions

Platinum-resistant Ovarian Cancer
Testicular Cancer
Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT06514937 | COMPLETED | NA

250 participants

Efficacy of the E-motional Training Program for Improving Social Cognition in People With Dual Pathology in a Clinical and Prison Environment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-04-12
Completion:: 2024-04-12

Conditions

Social Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT06514794 | RECRUITING | PHASE2

125 participants

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-01-31
Completion:: 2026-12-30

Conditions

T-cell Acute Lymphoblastic Leukemia
Lymphoblastic Lymphoma

Interventions

BIOLOGICAL

No Results Yet

NCT06500377 | SUSPENDED | NA

44 participants

Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-06-17
Completion:: 2027-03-12

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Interventions

PROCEDURE
OTHER

No Results Yet