Clinical Trials Updated in 2026

NCT06587230 | RECRUITING | NA

312 participants

Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-08
Completion:: 2026-10-31

Conditions

Child Behavior
Mental Health Issue
Psychosocial Functioning
Depression
Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT06567743 | RECRUITING | PHASE2

325 participants

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-09-16
Completion:: 2027-03-31

Conditions

High-Risk Non-Muscle-Invasive Bladder Cancer

Interventions

DRUG

No Results Yet

NCT06563167 | ACTIVE_NOT_RECRUITING

330 participants

Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-09-01
Completion:: 2026-12-31

Conditions

Lung Biopsy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06560398 | RECRUITING | NA

7649 participants

Working Through Outreach, Navigation and Digital Enabled Referral and Recruitment Strategies (ACT WONDER²S)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-09-18
Completion:: 2026-09-16

Conditions

Cancer

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06557707 | RECRUITING

120 participants

Cardiovascular Health & Early Stress

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-01-20
Completion:: 2027-12-31

Conditions

Stress

Interventions

OTHER

No Results Yet

NCT06555419 | RECRUITING | PHASE1

78 participants

A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-01-16
Completion:: 2027-09-30

Conditions

Muscular Atrophy, Spinal

Interventions

DRUG
DEVICE

No Results Yet

NCT06554327 | RECRUITING | NA

265 participants

Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-03-06
Completion:: 2030-09-06

Conditions

Ventilator Associated Pneumonia

Interventions

DEVICE

No Results Yet

NCT06545877 | COMPLETED

571 participants

REKOVELLE PEN for S.C. Injection General Drug Use Survey (Controlled Ovarian Stimulation in Assisted Reproductive Technologies)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-09-16
Completion:: 2025-04-30

Conditions

Infertility

No Results Yet

NCT06541262 | RECRUITING | PHASE1/PHASE2

104 participants

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-10-30
Completion:: 2030-11-01

Conditions

Neuroblastoma
Ewing Sarcoma
Osteosarcoma
Rhabdomyosarcoma
Liposarcoma

Interventions

DRUG

No Results Yet

NCT06540963 | RECRUITING | PHASE2

98 participants

Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-12-06
Completion:: 2030-12-01

Conditions

Neuroblastoma

Interventions

DRUG

No Results Yet

NCT06538870 | RECRUITING | NA

30 participants

Dental Implant Healing With TNF-Alpha Inhibitors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-06-28
Completion:: 2026-12-31

Conditions

Edentulism
Dental Implants
TNF-alpha Inhibitors

Interventions

PROCEDURE

No Results Yet

NCT06535516 | RECRUITING | NA

60 participants

Resilient Roots: Supporting Youth and Families

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-15
Completion:: 2027-08-01

Conditions

Posttraumatic Stress Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06524414 | ACTIVE_NOT_RECRUITING | PHASE2

605 participants

A Study to Learn About How a New Pneumococcal Vaccine Works in Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-25
Completion:: 2027-05-01

Conditions

Pneumococcal Disease

Interventions

BIOLOGICAL

No Results Yet

NCT06515613 | RECRUITING | PHASE1

156 participants

A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-10
Completion:: 2028-05-31

Conditions

Platinum-resistant Ovarian Cancer
Testicular Cancer
Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT06514937 | COMPLETED | NA

250 participants

Efficacy of the E-motional Training Program for Improving Social Cognition in People With Dual Pathology in a Clinical and Prison Environment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-04-12
Completion:: 2024-04-12

Conditions

Social Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT06514794 | RECRUITING | PHASE2

125 participants

A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-01-31
Completion:: 2026-12-30

Conditions

T-cell Acute Lymphoblastic Leukemia
Lymphoblastic Lymphoma

Interventions

BIOLOGICAL

No Results Yet

NCT06500377 | SUSPENDED | NA

44 participants

Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-06-17
Completion:: 2027-03-12

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06498635 | RECRUITING | PHASE3

306 participants

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-04-01
Completion:: 2039-07-15

Conditions

Lung Non-Small Cell Carcinoma
Stage II Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8

Interventions

PROCEDURE
BIOLOGICAL
OTHER

No Results Yet

NCT06497842 | COMPLETED | NA

14 participants

Effort During Resistance Training in Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-09-10
Completion:: 2026-03-05

Conditions

Type2 Diabetes Mellitus

Interventions

BEHAVIORAL

No Results Yet

NCT06472908 | ACTIVE_NOT_RECRUITING | PHASE3

8862 participants

Efficacy and Safety of Colchicine After PCI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-09
Completion:: 2027-06-30

Conditions

Coronary Heart Disease
Percutaneous Coronary Intervention
Colchicine

Interventions

DRUG

No Results Yet

NCT06470750 | COMPLETED

75 participants

Feasibility of Patient-Centered Home Care (PCHC) to Reduce Disparities in High-Risk Black Men (BM) With Prostate Cancer (CaP)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-25
Completion:: 2025-09-29

Conditions

Prostate Adenocarcinoma

Interventions

OTHER

No Results Yet

NCT06468956 | COMPLETED | PHASE3

652 participants

Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-06-14
Completion:: 2026-08-26

Conditions

Moderate to Severe Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06465953 | RECRUITING | PHASE3

48 participants

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-12-03
Completion:: 2027-11-01

Conditions

Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS)
Myelodysplastic Syndromes (MDS)

Interventions

DRUG

No Results Yet

NCT06465485 | COMPLETED | PHASE3

504 participants

STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With Severe Eosinophilic Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-02-28
Completion:: 2026-05-13

Conditions

Severe Eosinophilic Asthma

Interventions

DRUG

No Results Yet

NCT06465199 | RECRUITING | PHASE1/PHASE2

265 participants

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2026-05-13
Completion:: 2033-05-31

Conditions

Atypical Teratoid/Rhabdoid Tumor
Embryonal Tumor With Multilayered Rosettes
Ewing Sarcoma
Diffuse Intrinsic Pontine Glioma
Osteosarcoma
Neuroblastoma
DIPG Brain Tumor

Interventions

DRUG

No Results Yet

NCT06462469 | ACTIVE_NOT_RECRUITING | PHASE4

36 participants

Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV Steroid-refractory Acute Graft vs. Host Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-07-04
Completion:: 2026-09-02

Conditions

Steroid-refractory Acute Graft Versus Host Disease

Interventions

DRUG

No Results Yet

NCT06461026 | COMPLETED | PHASE1

327 participants

L9LS MAb in Malian Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-08-19
Completion:: 2025-06-27

Conditions

Malaria

Interventions

BIOLOGICAL
OTHER

Results Available

NCT06450197 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Phase IIa Study Evaluating AZD7798 in Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-08-28
Completion:: 2026-04-30

Conditions

Moderate to Severe Crohn's Disease

Interventions

DRUG
OTHER

No Results Yet

NCT06447246 | ENROLLING_BY_INVITATION

90 participants

Respiratory Effects of Obesity in Children: Longitudinal Consequences After 6 Years of Aging

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-08-23
Completion:: 2029-08-31

Conditions

Childhood Obesity

No Results Yet

NCT06447025 | RECRUITING | PHASE2

85 participants

An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-01-25
Completion:: 2027-01-31

Conditions

Friedreich Ataxia

Interventions

DRUG

No Results Yet

NCT06445972 | RECRUITING | PHASE1/PHASE2

210 participants

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-08-07
Completion:: 2028-05-09

Conditions

Gastroesophageal Junction
Gastroesophageal Adenocarcinoma
Esophageal Neoplasms
Esophageal Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06445348 | NOT_YET_RECRUITING

80 participants

Analysis of Sub Axial Cervical Pedicle Spine Based on CT

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2026-12-30
Completion:: 2027-05-21

Conditions

Cervical Pedicle Screw

Interventions

DEVICE

No Results Yet

NCT06442514 | NOT_YET_RECRUITING | NA

220 participants

Pain and Smoking Study 2

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2026-09-16
Completion:: 2028-05-31

Conditions

Smoking
Pain
Smoking Cessation

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06439706 | COMPLETED | NA

108 participants

HPV Self-sampling for Underscreened Latinas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-10-04
Completion:: 2024-09-30

Conditions

Uterine Cervical Neoplasm

Interventions

BEHAVIORAL

No Results Yet

NCT06430554 | RECRUITING

40 participants

Personalized Ventilation Based on Ventilation-perfusion Mismatch and Lung Recruitability

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-06-08
Completion:: 2026-12-30

Conditions

Respiratory Distress Syndrome
Positive-Pressure Respiration
Mechanical Ventilation

No Results Yet

NCT06428409 | RECRUITING | PHASE1/PHASE2

220 participants

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-06-20
Completion:: 2029-10-16

Conditions

Colorectal Cancer
Pancreatic Ductal Adenocarcinoma
Biliary Tract Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06428175 | RECRUITING | NA

480 participants

Hospital-to-Home Transitional Care Interventions (H2H-TCI) Children/Youth With Special Health Care Needs (CYSHCN)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2025-08-28
Completion:: 2028-08-31

Conditions

Health Care
Pediatrics
Transitional Care
Comparative Effectiveness
Family Engagement

Interventions

BEHAVIORAL

No Results Yet

NCT06426563 | RECRUITING | NA

150 participants

MWA vs RFA for the Treatment of Moderate-sized Benign Thyroid Nodules

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-04-15
Completion:: 2027-12-31

Conditions

Thyroid Nodule \(Benign\)
Ablation Therapy

Interventions

PROCEDURE

No Results Yet

NCT06423950 | RECRUITING

35 participants

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-05-01
Completion:: 2027-04-30

Conditions

Pediatric Cancer

Interventions

OTHER

No Results Yet

NCT06422806 | RECRUITING | PHASE3

365 participants

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-09-11
Completion:: 2032-04-18

Conditions

Metastatic Dedifferentiated Liposarcoma
Metastatic Undifferentiated Pleomorphic Sarcoma
Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Unresectable Dedifferentiated Liposarcoma
Unresectable Undifferentiated Pleomorphic Sarcoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet