Clinical Trials Updated in 2026

NCT07074119 | NOT_YET_RECRUITING | NA

218 participants

Sensor-Based Optimization of Therapy for Parkinson's Disease Patients With Motor Fluctuations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-10-31
Completion:: 2029-04-01

Conditions

Parkinson Disease (PD)

Interventions

DEVICE

No Results Yet

NCT07072611 | COMPLETED | EARLY_PHASE1

24 participants

Clinical Trial to Evaluate Safety, Tolerability, and Pharmacokinetics of SOF-SKN in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-07-14
Completion:: 2025-12-27

Conditions

Cutaneous Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT07072286 | RECRUITING

177 participants

RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-07-25
Completion:: 2026-10-25

Conditions

Pelvic Bone Injury
Pelvis Injury
Acetabular Fractures
Acetabular Surgery
Trauma Injury

Interventions

PROCEDURE
DRUG

No Results Yet

NCT07070232 | RECRUITING | PHASE1/PHASE2

1438 participants

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-08-12
Completion:: 2028-03-31

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT07062406 | RECRUITING | NA

30 participants

Enhancing Diabetes Care by Treating Insomnia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-09-01
Completion:: 2027-06-30

Conditions

Diabetes Type 2
Insomnia

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07061574 | RECRUITING | PHASE1/PHASE2

120 participants

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-03-10
Completion:: 2030-04-15

Conditions

Type 1 Diabetes
New Onset

Interventions

DRUG

No Results Yet

NCT07061288 | RECRUITING | PHASE1

131 participants

A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-09-03
Completion:: 2027-06-21

Conditions

Schizophrenia

Interventions

DRUG

No Results Yet

NCT07059819 | ENROLLING_BY_INVITATION | NA

400 participants

Local Hyperthermia for the Treatment of Cervical Persistent High-risk Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-11-02
Completion:: 2026-10-01

Conditions

Cervical Intraepithelial Neoplasia (CIN)
Human Papillovirus

Interventions

DEVICE

No Results Yet

NCT07058532 | WITHDRAWN | NA

0 participants

Therapeutic Writing for Adults Suffering From Chronic Pain and Comorbid Mental Health Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-09-30
Completion:: 2026-04-30

Conditions

Chronic Pain
Mental Health Disorder
Psychiatric &Amp;Amp;or Mood Disorder
Psychiatric Comorbidities
Psychiatric Diagnosis
Emotional Pain
Emotional Distress
Emotion Regulation
Emotional Processing
Meaning of Life
Meaning Made
Meaning of Life and Life Satisfaction
Depressive Disorder
Anxiety Disorders
Sleep Disorder
Comorbid Depression
Process, Acceptance

Interventions

OTHER

No Results Yet

NCT07049926 | RECRUITING | PHASE1/PHASE2

140 participants

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-07-20
Completion:: 2031-10-26

Conditions

Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07040683 | RECRUITING | NA

232 participants

Lower Extremity Graft Study (LEGS): A Multicentre Randomised Controlled Trial of Negative Pressure Wound Therapy Versus Conventional Dressings for Split-thickness Skin Grafts After Lower Leg Skin Tumour Excision

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-11-01
Completion:: 2030-01-01

Conditions

Skin Transplantation
Skin Grafting
Split Thickness Skin Graft
Negative-Pressure Wound Therapy
Postoperative Complications
Surgical Wound Infection
Lower Extremity
Skin Cancer
Skin Tumour
Wound Healing
Bandages
Leg

Interventions

DEVICE
OTHER

No Results Yet

NCT07036523 | RECRUITING | PHASE2

71 participants

A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-11-13
Completion:: 2027-03-11

Conditions

Idiopathic Pulmonary Fibrosis

Interventions

DRUG

No Results Yet

NCT07029776 | NOT_YET_RECRUITING | PHASE2

50 participants

MMulti-Immune HR; Multi-Target Immunotherapy for High-Risk Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2027-03-01
Completion:: 2030-04-01

Conditions

Multiple Myeloma (MM)

Interventions

DRUG
PROCEDURE

No Results Yet

NCT07029126 | COMPLETED

308 participants

Improving the Perception of Stress and Mutuality in Caregivers (MI-DEAR Study) of Migraine Patients With Depressive Symptoms Treated With Fremanezumab: A Study to Evaluate Whether Fremanezumab Reduces the Impact on Caregivers and Increases Couple Reciprocity

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-10-03
Completion:: 2026-03-30

Conditions

Migraine

Interventions

DRUG

No Results Yet

NCT07028749 | RECRUITING | PHASE2

316 participants

Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-06-30
Completion:: 2027-11-30

Conditions

Hypertriglyceridemia

Interventions

DRUG

No Results Yet

NCT07027514 | RECRUITING | PHASE1

60 participants

A Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-10-22
Completion:: 2027-06-30

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07025824 | RECRUITING | PHASE2

220 participants

Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-01-21
Completion:: 2029-09-30

Conditions

AML - Acute Myeloid Leukemia
MDS (Myelodysplastic Syndrome)

Interventions

DRUG

No Results Yet

NCT07025785 | RECRUITING | NA

100 participants

Molecular Residual Disease Assessment in a Representative Diverse Population of Patients With Early-stage Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-08-22
Completion:: 2030-09-01

Conditions

Breast Cancer
Lymph Node Metastasis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07024615 | RECRUITING | PHASE1

25 participants

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-10-16
Completion:: 2028-01-31

Conditions

Pancreatic Ductal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT07022314 | RECRUITING

45 participants

Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-01-01
Completion:: 2027-06-30

Conditions

AKI - Acute Kidney Injury
Cardiac Surgery
Fluid Therapy
Hemodynamic Instability
Postoperative Complications

Interventions

DEVICE

No Results Yet

NCT07021248 | COMPLETED | PHASE4

249 participants

A Randomized Controlled Trial Evaluating the Impact of Procedure-Specific Bariatric Supplements on Micronutrient Status and Vitamin B6 Hypervitaminosis Following Metabolic and Bariatric Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-06-15
Completion:: 2026-06-21

Conditions

Micronutrient Status

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07021170 | COMPLETED | PHASE4

624 participants

Trial Comparing Elan Specialized Bariatric Supplements With Standard Multivitamins in Patients Undergoing Bariatric Procedures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-06-15
Completion:: 2026-06-14

Conditions

Vitamin Deficiencies

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07020832 | WITHDRAWN | PHASE3

0 participants

Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults at High Risk of Delayed Graft Function (DGF) Following Kidney Allograft Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-05-18
Completion:: 2029-06-30

Conditions

Delayed Graft Function
End Stage Renal Disease
Deceased Donor Kidney Transplant

Interventions

DRUG
OTHER

No Results Yet

NCT07018739 | NOT_YET_RECRUITING | PHASE1/PHASE2

40 participants

Mesenchymal Stem Cells With Cooling Therapy for Infants With Hypoxic-Ischemic Encephalopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-09-15
Completion:: 2032-12-31

Conditions

Hypoxic-Ischemic Encephalopathy, Neonatal
Brain Injuries, Hypoxic-Ischemic

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07018713 | RECRUITING | PHASE3

780 participants

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-08-21
Completion:: 2027-10-31

Conditions

Chronic Migraine

Interventions

DRUG

No Results Yet

NCT07018700 | RECRUITING | PHASE3

990 participants

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-08-21
Completion:: 2027-03-31

Conditions

Episodic Migraine

Interventions

DRUG

No Results Yet

NCT07014748 | COMPLETED

600 participants

SAFETY: Stabilization Points to Third Hospital Line Assessment oF the Impact of the usE of Infrascanner Model 2500 to Provide Decision Support for Diagnosis/Screening of Traumatic Brain InjurY in Ukraine

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-01-17
Completion:: 2026-03-28

Conditions

Traumatic Brain Hemorrhage

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07014111 | RECRUITING | NA

40 participants

Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-09-02
Completion:: 2027-02-28

Conditions

End Stage Renal Disease on Dialysis

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07011719 | RECRUITING | PHASE3

720 participants

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-09-08
Completion:: 2028-04-30

Conditions

Metastatic Clear Cell Renal Cell Carcinoma
Advanced Clear Cell Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07003737 | RECRUITING | NA

114 participants

Blinatumomab Intensification for MRD-Negative Acute B-Cell Lymphoblastic Leukemia Before Allogeneic Hematopoietic Stem Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-02-05
Completion:: 2027-02-05

Conditions

Acute Lymphoblastic Leukemia, B-precursor

Interventions

DRUG
OTHER

No Results Yet

NCT07002476 | RECRUITING | PHASE3

978 participants

Early Aggressive Strategy for Treatment of Lipid-Lowering in Acute Ischemic Stroke Delivered With Endovascular Therapy for Large Artery Occlusion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-06-19
Completion:: 2027-03-01

Conditions

Stroke

Interventions

DRUG

No Results Yet

NCT07002398 | RECRUITING | PHASE1/PHASE2

18 participants

Safety and Preliminary Efficacy of VG801 in Patients With ABCA4 Mutation-associated Retinal Dystrophy (Stargardt Disease)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-12-23
Completion:: 2027-12-31

Conditions

Retinal Dystrophy Due to Biallelic ABCA4 Mutations
Stargardt Disease 1

Interventions

DRUG

No Results Yet

NCT07000253 | RECRUITING | PHASE2

290 participants

Timing of Minimally Invasive Local Treatment After First-Line Systemic Therapy in Oligometastatic Esophageal or Gastric Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-04-29
Completion:: 2031-11-30

Conditions

Esophageal Cancer
Gastric (Stomach) Cancer
Gastric Adenocarcinoma
Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma
Esophageal Carcinoma
Gastric (Cardia, Body) Cancer

Interventions

DRUG
PROCEDURE
RADIATION

No Results Yet

NCT06996730 | RECRUITING | PHASE2/PHASE3

240 participants

A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2026-07-08
Completion:: 2030-06-01

Conditions

Autosomal Dominant Alzheimers Disease
Early Onset Alzheimer Disease
Alzheimers Disease

Interventions

DRUG

No Results Yet

NCT06995898 | RECRUITING | NA

24000 participants

The Vanguard Study: Testing a New Way to Screen for Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-06-18
Completion:: 2029-01-31

Conditions

Bladder Carcinoma
Breast Carcinoma
Colorectal Carcinoma
Esophageal Carcinoma
Gastric Carcinoma
Liver Carcinoma
Lung Carcinoma
Malignant Solid Neoplasm
Ovarian Carcinoma
Pancreatic Carcinoma
Prostate Carcinoma

Interventions

PROCEDURE
DEVICE
OTHER

No Results Yet

NCT06995833 | RECRUITING

50 participants

Durvalumab With or Without Olaparib in Patients With Endometrial Cancers Regulatory Post Marketing Surveillance

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-09-19
Completion:: 2029-06-29

Conditions

Endometrial Cancer

No Results Yet

NCT06995014 | TERMINATED | NA

7 participants

Retrieval-based Word Learning in Developmental Language Disorder: Adaptive Retrieval Schedule

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2024-08-15
Completion:: 2025-12-31

Conditions

Developmental Language Disorder
Specific Language Impairment
Language Development

Interventions

BEHAVIORAL

Results Available

NCT06994624 | WITHDRAWN | NA

0 participants

Clinical and Biochemical Effects of a Defined Plant-Based Diet on Heart Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-04-25
Completion:: 2025-04-25

Conditions

Coronary Artery Disease

Interventions

OTHER

No Results Yet

NCT06993103 | RECRUITING | PHASE4

1444 participants

Pasteurised Donor Human Milk Supplementation for Term Babies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-12-04
Completion:: 2028-04-30

Conditions

Neonatal Hypoglycemia
Metabolic Complication
Cows Milk Allergy
Hospital Length of Stay
Neonatal Intensive Care Unit
Breastfeeding
Mental Health Issue

Interventions

OTHER
DIETARY_SUPPLEMENT

No Results Yet

NCT06988488 | RECRUITING | PHASE1/PHASE2

62 participants

A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-02
Start Date:: 2025-10-07
Completion:: 2027-05-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet