Clinical Trials

NCT05531786 | RECRUITING | PHASE1/PHASE2

50 participants

Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-03-06

Completion:

2027-07-22

Conditions

• Graft vs Host Disease

Interventions

• DRUG

No Results Yet

NCT05528172 | COMPLETED | PHASE3

330 participants

A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-08-04

Completion:

2023-06-22

Conditions

• Corneal Edema After Cataract Surgery

Interventions

• DRUG

Results Available

NCT05522205 | ACTIVE_NOT_RECRUITING | NA

374 participants

Regulated Cannabis Access in Basel

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-01-31

Completion:

2027-01-31

Conditions

• Cannabis Use Disorder
• Mental Health Disorder
• Physical Illness

Interventions

• OTHER

No Results Yet

NCT05519085 | RECRUITING | PHASE3

810 participants

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-09-20

Completion:

2027-01-10

Conditions

• Relapsed or Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05514431 | ENROLLING_BY_INVITATION

1500 participants

Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2017-02-01

Completion:

2027-07-31

Conditions

• Anesthesia
• Analgesia

Interventions

• PROCEDURE

No Results Yet

NCT05508763 | ACTIVE_NOT_RECRUITING

2000 participants

Personalised Therapeutics @LUMC

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2022-12-01

Completion:

2026-09-30

Conditions

• Adverse Drug Reaction

Interventions

• GENETIC

No Results Yet

NCT05506943 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

168 participants

A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-01-09

Completion:

2027-08-31

Conditions

• Biliary Tract Cancer
• Cholangiocarcinoma
• Gall Bladder Cancer
• Ampullary Cancer

Interventions

• DRUG

No Results Yet

NCT05483426 | RECRUITING | NA

200 participants

Prevalence of Sexual Addiction in an Inmate Population at the Muret Detention Center in Haute-Garonne (PAS-CD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-04-26

Completion:

2027-04-26

Conditions

• Sexual Addiction

Interventions

• OTHER

No Results Yet

NCT05476926 | ACTIVE_NOT_RECRUITING

6000 participants

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2022-11-21

Completion:

2026-11-30

Conditions

• Neovascular Age-related Macular Degeneration
• Diabetic Macular Edema
• Retinal Vein Occlusion
• Branch Retinal Vein Occlusion
• Central Retinal Vein Occlusion
• Hemi-retinal Vein Occlusion

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT05470777 | ACTIVE_NOT_RECRUITING | PHASE2

37 participants

CD22/CD19 CAR-T and Auto-HSCT Sandwich Strategy as Consolidation Therapy for B-ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2020-01-19

Completion:

2027-07-21

Conditions

• B-cell Acute Lymphoblastic Leukemia

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT05467085 | ACTIVE_NOT_RECRUITING | NA

20 participants

Imaging-Guided Low Intensity Focused Ultrasound (LIFU)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-08-01

Completion:

2027-08-01

Conditions

• Obsessive-Compulsive Disorder

Interventions

• DEVICE

No Results Yet

NCT05435508 | COMPLETED | NA

62 participants

Efficacy of Pain Neuroscience Education and Pre-anesthetic Assessment in Reducing Levels of Anxiety, Stress and Pain in Patients Undergoing Elective Total Abdominal Hysterectomy (ENAH Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2024-07-01

Completion:

2025-02-28

Conditions

• Pain, Chronic
• Pain, Postoperative
• Anesthesia
• Surgery
• Anxiety
• Stress

Interventions

• OTHER

No Results Yet

NCT05432804 | RECRUITING | PHASE1/PHASE2

97 participants

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-03-20

Completion:

2027-06-30

Conditions

• Recurrent Glioblastoma, IDH-Wildtype
• Recurrent MGMT-Methylated Glioblastoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05407168 | ACTIVE_NOT_RECRUITING | NA

237 participants

Improving Decision-Making Encounters in Lung Cancer Using a Low-Literacy Conversation Tool

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-10-31

Completion:

2027-03-31

Conditions

• Lung Carcinoma

Interventions

• OTHER

No Results Yet

NCT05405166 | ACTIVE_NOT_RECRUITING | PHASE3

531 participants

SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-06-23

Completion:

2024-11-06

Conditions

• Plasma Cell Myeloma Recurrent

Interventions

• DRUG

Results Available

NCT05402033 | RECRUITING

1200 participants

Cancer Clinical Trials Financial Reimbursement Program

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2022-07-12

Completion:

2029-06-01

Conditions

• Cancer Clinical Trials

Interventions

• BEHAVIORAL

No Results Yet

NCT05393778 | ACTIVE_NOT_RECRUITING | NA

100 participants

Measured vs Navigated Techniques in Total Hip Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2024-01-30

Completion:

2025-12-10

Conditions

• Osteoarthritis, Hip

Interventions

• PROCEDURE

No Results Yet

NCT05376267 | RECRUITING | NA

900 participants

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-08-05

Completion:

2028-03-31

Conditions

• Cardiac Arrest, Out-Of-Hospital
• Hypothermia, Induced
• Hypoxia-Ischemia, Brain

Interventions

• DEVICE

No Results Yet

NCT05356962 | COMPLETED | NA

400 participants

STOP? II: Testing of a Toolbox for Structured Communication in the Operating Room

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-08-01

Completion:

2026-05-19

Conditions

• Communication Research
• Communication, Multidisciplinary

Interventions

• BEHAVIORAL

No Results Yet

NCT05350761 | RECRUITING

500 participants

Rare Tumors and Cancer Predisposition in Individuals and Families

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2023-03-10

Completion:

2035-12-31

Conditions

• Cancer
• Hereditary Neoplasms
• Genetic Predisposition to Cancer
• Environment

No Results Yet

NCT05334069 | RECRUITING

2000 participants

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2022-08-18

Completion:

2027-01-31

Conditions

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Ann Arbor Stage I Lymphoma
• Ann Arbor Stage II Lymphoma
• Ann Arbor Stage III Lymphoma
• Ann Arbor Stage IV Lymphoma
• Chronic Lymphocytic Leukemia
• Chronic Myeloid Leukemia
• Gastroesophageal Junction Adenocarcinoma
• Head and Neck Carcinoma
• Hematopoietic and Lymphoid Cell Neoplasm
• Invasive Breast Carcinoma
• Kidney Carcinoma
• Malignant Hepatobiliary Neoplasm
• Malignant Solid Neoplasm
• Melanoma
• Muscle-Invasive Bladder Carcinoma
• RISS Stage I Plasma Cell Myeloma
• RISS Stage II Plasma Cell Myeloma
• RISS Stage III Plasma Cell Myeloma
• Sarcoma
• Stage I Bladder Cancer AJCC v6 and v7
• Stage I Breast Cancer AJCC v7
• Stage I Colorectal Cancer AJCC v6 and v7
• Stage I Esophageal Cancer AJCC V7
• Stage I Gastric Cancer AJCC V7
• Stage I Lung Cancer AJCC v7
• Stage I Ovarian Cancer AJCC v6 and v7
• Stage I Pancreatic Cancer AJCC v6 and v7
• Stage I Prostate Cancer AJCC v7
• Stage I Uterine Corpus Cancer AJCC v7
• Stage II Bladder Cancer AJCC v6 and v7
• Stage II Breast Cancer AJCC v6 and v7
• Stage II Colorectal Cancer AJCC v7
• Stage II Esophageal Cancer AJCC v7
• Stage II Gastric Cancer AJCC v7
• Stage II Lung Cancer AJCC v7
• Stage II Ovarian Cancer AJCC v6 and v7
• Stage II Pancreatic Cancer AJCC v6 and v7
• Stage II Prostate Cancer AJCC v7
• Stage II Uterine Corpus Cancer AJCC v7
• Stage III Bladder Cancer AJCC v6 and v7
• Stage III Breast Cancer AJCC v7
• Stage III Colorectal Cancer AJCC v7
• Stage III Esophageal Cancer AJCC v7
• Stage III Gastric Cancer AJCC v7
• Stage III Lung Cancer AJCC v7
• Stage III Ovarian Cancer AJCC v6 and v7
• Stage III Pancreatic Cancer AJCC v6 and v7
• Stage III Prostate Cancer AJCC v7
• Stage III Uterine Corpus Cancer AJCC v7
• Stage IV Bladder Cancer AJCC v7
• Stage IV Breast Cancer AJCC v6 and v7
• Stage IV Colorectal Cancer AJCC v7
• Stage IV Esophageal Cancer AJCC v7
• Stage IV Gastric Cancer AJCC v7
• Stage IV Lung Cancer AJCC v7
• Stage IV Ovarian Cancer AJCC v6 and v7
• Stage IV Pancreatic Cancer AJCC v6 and v7
• Stage IV Prostate Cancer AJCC v7
• Stage IV Uterine Corpus Cancer AJCC v7
• Thyroid Gland Carcinoma

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT05326386 | COMPLETED | NA

43 participants

Gamification and Medication Adherence (GAME Adherence)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-09-12

Completion:

2024-01-31

Conditions

• Hypertension and Hyperlipidemia

Interventions

• BEHAVIORAL

No Results Yet

NCT05319730 | RECRUITING | PHASE1/PHASE2

230 participants

A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-05-16

Completion:

2027-06-11

Conditions

• Esophageal Squamous Cell Carcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05310578 | RECRUITING

154 participants

Functioning in Individuals With Cervical Radiculopathy After Posterior Cervical Decompression

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2022-08-22

Completion:

2026-12-31

Conditions

• Cervical Radiculopathy

Interventions

• PROCEDURE

No Results Yet

NCT05286814 | RECRUITING | PHASE2

70 participants

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-10-24

Completion:

2027-12-31

Conditions

• Metastatic Colorectal Cancer (Mcrc)
• Intrahepatic Cholangiocarcinoma (Icc)
• Intrahepatic Bile Duct Cancer
• Colorectal Neoplasms
• Colorectal Cancer
• Cholangiocarcinoma
• Bile Duct Neoplasms
• Bile Duct Cancer
• Adrenocortical Carcinoma (ACC)
• Adrenal Cortical Carcinoma
• Adrenal Gland Cancer
• Adrenal Gland Neoplasms
• Adrenal Cortex Neoplasms

Interventions

• DRUG
• DEVICE

No Results Yet

NCT05251454 | ACTIVE_NOT_RECRUITING | NA

5 participants

Studying the Effects of Brain Stimulation on Cognitive Control and Associated EEG in Human Subjects.

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-06-20

Completion:

2025-04-30

Conditions

• Cognitive Deficit

Interventions

• PROCEDURE

No Results Yet

NCT05247905 | ACTIVE_NOT_RECRUITING | PHASE2

31 participants

Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors, the ComPareNET Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-02-16

Completion:

2028-03-31

Conditions

• Metastatic Pancreatic Neuroendocrine Tumor
• Unresectable Pancreatic Neuroendocrine Carcinoma

Interventions

• DRUG
• OTHER

No Results Yet

NCT05245500 | RECRUITING | PHASE1

336 participants

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-06-09

Completion:

2027-12-10

Conditions

• Mesothelioma
• Non Small Cell Lung Cancer
• Malignant Peripheral Nerve Sheath Tumors
• Solid Tumor
• Pancreatic Adenocarcinoma
• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05237960 | ACTIVE_NOT_RECRUITING | PHASE2

34 participants

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-01-12

Completion:

2025-11-07

Conditions

• Erythroplakia
• Oral Leukoplakia

Interventions

• PROCEDURE
• DRUG

Results Available

NCT05224154 | COMPLETED | NA

9 participants

Re-Connect Application for Smoking Cessation

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2021-12-14

Completion:

2026-02-28

Conditions

• Smoking Cessation
• Acceptability of Health Care
• Nicotine Dependence, Cigarettes

Interventions

• BEHAVIORAL

No Results Yet

NCT05202353 | ACTIVE_NOT_RECRUITING | PHASE1

29 participants

A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2024-11-01

Completion:

2027-01-06

Conditions

• Obesity

Interventions

• DRUG

No Results Yet

NCT05174169 | RECRUITING | PHASE2/PHASE3

1912 participants

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-07-08

Completion:

2029-03-10

Conditions

• Stage III Colon Cancer

Interventions

• DEVICE
• DRUG

No Results Yet

NCT05173389 | COMPLETED | NA

46 participants

Distal Versus Proximal Balance Training in Chronic Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2019-08-01

Completion:

2021-07-20

Conditions

• Chronic Stroke

Interventions

• DEVICE

No Results Yet

NCT05142293 | COMPLETED

354 participants

One Day Implantation Program for Heart Failure Patients Implanted With CRT-P

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2021-12-06

Completion:

2025-07-24

Conditions

• Heart Failure

Interventions

• OTHER

No Results Yet

NCT05131750 | RECRUITING

1408 participants

RIR and the Impact on Clinical Outcomes in Patients Undergoing PCI

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2021-05-06

Completion:

2028-05-31

Conditions

• hsCRP

No Results Yet

NCT05112237 | ACTIVE_NOT_RECRUITING

200 participants

Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-02

Start Date:

2021-11-01

Completion:

2028-06-30

Conditions

• Cardiomyopathy

No Results Yet

NCT05089370 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

8 participants

Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-06-20

Completion:

2026-08-10

Conditions

• Malignant Melanoma

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT05080673 | RECRUITING | NA

9500 participants

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-02-09

Completion:

2035-11-01

Conditions

• Adenocarcinoma of the Colon
• Adenocarcinoma of the Rectum

Interventions

• PROCEDURE

No Results Yet

NCT05073575 | COMPLETED | NA

80 participants

Application of Hyaluronic Acid in the Treatment of Periodontitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2023-01-01

Completion:

2024-07-01

Conditions

• Periodontal Bone Loss

Interventions

• PROCEDURE

No Results Yet

NCT05057494 | ACTIVE_NOT_RECRUITING | PHASE3

607 participants

A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-02

Start Date:

2022-09-12

Completion:

2027-07-15

Conditions

• Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Interventions

• DRUG

No Results Yet