Clinical Trials

NCT04008706 | COMPLETED | PHASE3

552 participants

Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-09-17

Completion:

2025-11-04

Conditions

• Chronic Lymphocytic Leukemia

Interventions

• DRUG

Results Available

NCT03998254 | ACTIVE_NOT_RECRUITING | PHASE3

6000 participants

Efficacy, Immunogenicity and Safety of V503 in Chinese Women Aged 20-45 Years (V503-023)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-06-26

Completion:

2028-03-31

Conditions

• Papillomavirus Infections

Interventions

• DRUG

No Results Yet

NCT03976843 | ACTIVE_NOT_RECRUITING | PHASE2

175 participants

Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-12-04

Completion:

2027-11-19

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT03950076 | COMPLETED | PHASE4

948 participants

EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-09-20

Completion:

2026-07-22

Conditions

• Intracranial Hemorrhages
• Atrial Fibrillation

Interventions

• DRUG
• OTHER

No Results Yet

NCT03937830 | ACTIVE_NOT_RECRUITING | PHASE2

27 participants

Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2021-03-10

Completion:

2026-12-31

Conditions

• Hepatocellular Cancer
• Hepatocellular Carcinoma
• Metastatic Hepatocellular Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03937817 | RECRUITING

300 participants

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2019-09-25

Completion:

2029-03-31

Conditions

• Alpha and Beta Thalassemia
• Sickle Cell Disease
• Malaria
• Human Physiology

No Results Yet

NCT03937804 | COMPLETED

83 participants

New Approaches for Empowering Studies of Asthma in Populations of African Descent

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2019-09-23

Completion:

2021-07-15

Conditions

• Asthma

No Results Yet

NCT03929601 | ACTIVE_NOT_RECRUITING | PHASE2

74 participants

Rituximab-pvvr and Abatacept vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2023-10-30

Completion:

2027-03-31

Conditions

• Type 1 Diabetes Mellitus

Interventions

• DRUG

No Results Yet

NCT03922724 | ACTIVE_NOT_RECRUITING | PHASE2

91 participants

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-04-18

Completion:

2027-06-01

Conditions

• Peripheral T-cell Lymphomas
• Lymphoproliferative Disorders
• Immune System Diseases

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03911388 | RECRUITING | PHASE1

24 participants

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-09-12

Completion:

2026-09-01

Conditions

• Neoplasms, Brain
• Glioblastoma Multiforme
• Glioblastoma of Cerebellum
• Neoplasms
• Astrocytoma
• Astrocytoma, Cerebellar
• Neuroectodermal Tumors
• Neuroectodermal Tumors, Primitive
• Cerebellar PNET, Childhood
• Cerebellar Neoplasms
• Cerebellar Neoplasms, Primary
• Cerebellar Neoplasm, Malignant
• Cerebellar Neoplasm Malignant Primary
• Neoplasm Metastases
• Neoplasm Malignant
• Neoplasms, Neuroepithelial
• Neoplasms, Germ Cell and Embryonal
• Neoplasms by Histologic Type
• Neoplasms, Glandular and Epithelial
• Neoplasms, Nerve Tissue
• Central Nervous System Neoplasms, Primary
• Central Nervous System Neoplasms, Malignant
• Nervous System Neoplasms
• Neoplasms by Site
• Brain Diseases
• Central Nervous System Diseases
• Nervous System Diseases
• Medulloblastoma Recurrent
• HSV
• Virus
• Pediatric Brain Tumor
• Nervous System Cancer
• Primitive Neuroectodermal Tumor (PNET) of Cerebellum

Interventions

• BIOLOGICAL

No Results Yet

NCT03910452 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

4 participants

Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-10-28

Completion:

2034-06-15

Conditions

• Chronic Granulomatous Disease

Interventions

• DRUG
• RADIATION
• BIOLOGICAL

No Results Yet

NCT03900793 | RECRUITING | PHASE1

41 participants

Losartan + Sunitinib in Treatment of Osteosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-08-26

Completion:

2027-08-01

Conditions

• Osteosarcoma

Interventions

• DRUG

No Results Yet

NCT03886246 | ACTIVE_NOT_RECRUITING | PHASE2

131 participants

Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-05-29

Completion:

2027-09-30

Conditions

• Generalized Pustular Psoriasis

Interventions

• DRUG

No Results Yet

NCT03867448 | RECRUITING

1000 participants

Study of Endocrine-Related Conditions and Physiology

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2019-03-27

Completion:

2036-01-01

Conditions

• Endocrine Disease

Interventions

• DEVICE

No Results Yet

NCT03831958 | RECRUITING

600 participants

Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2019-03-04

Completion:

2040-01-03

Conditions

• Cushing Disease

No Results Yet

NCT03801434 | ACTIVE_NOT_RECRUITING | PHASE2

8 participants

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-11-15

Completion:

2029-02-28

Conditions

• BCR-JAK2 Fusion Protein Expression
• Blasts 20 Percent or Less of Peripheral Blood White Cells
• Blasts More Than 5 Percent of Bone Marrow Nucleated Cells
• Blasts More Than 5 Percent of Peripheral Blood White Cells
• Blasts Under 20 Percent of Bone Marrow Nucleated Cells
• Chronic Eosinophilic Leukemia, Not Otherwise Specified
• Eosinophilia
• Hepatomegaly
• Hypereosinophilic Syndrome
• JAK2 Gene Mutation
• Splenomegaly
• TEL-JAK2 Fusion Protein Expression

Interventions

• DRUG

No Results Yet

NCT03773523 | ACTIVE_NOT_RECRUITING | NA

30 participants

Neuromodulation and Cognitive Training in Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-08-01

Completion:

2027-05-15

Conditions

• Opioid-use Disorder
• Opioid Dependence
• Opioid Abuse

Interventions

• DEVICE

No Results Yet

NCT03766971 | SUSPENDED | PHASE2

160 participants

Influence of Tobacco Use on Cannabis Use

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2020-02-01

Completion:

2027-11-30

Conditions

• Cannabis Use
• Tobacco Use

Interventions

• BEHAVIORAL
• DRUG

No Results Yet

NCT03762733 | ENROLLING_BY_INVITATION

500 participants

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2022-01-04

Completion:

2028-12-29

Conditions

• Breast Cancer
• Ovarian Cancer
• Uterine Cancer

No Results Yet

NCT03755895 | COMPLETED | PHASE2

68 participants

Contribution of Hypnosis to Anxiety and Pain in Brachytherapy Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-11-02

Completion:

2022-05-17

Conditions

• Cancer
• Brachytherapy

Interventions

• OTHER
• DRUG

No Results Yet

NCT03752697 | COMPLETED

30 participants

Metacognition in Neurological Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-12-13

Completion:

2023-03-30

Conditions

• Brain Injuries

Interventions

• BEHAVIORAL

No Results Yet

NCT03733093 | COMPLETED

1377 participants

PREVAIL VIII: A CoHOrt Clinical, Viral, and ImmuNOlogic Monitoring Study of People Living With Retroviral Infection in Liberia (HONOR)

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2019-08-22

Completion:

2025-12-31

Conditions

• HIV

No Results Yet

NCT03729115 | RECRUITING | NA

400 participants

A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-05-30

Completion:

2028-12-31

Conditions

• Breast Cancer

Interventions

• PROCEDURE

No Results Yet

NCT03727555 | NOT_YET_RECRUITING | NA

30 participants

IT and IV Lentiviral Gene Therapy for X-ALD

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2027-06-01

Completion:

2028-05-31

Conditions

• X-linked Adrenoleukodystrophy

Interventions

• GENETIC

No Results Yet

NCT03725670 | NOT_YET_RECRUITING | NA

10 participants

Direct Lentiviral Injection Gene Therapy for MLD

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2027-05-31

Completion:

2028-06-01

Conditions

• Metachromatic Leukodystrophy (MLD)

Interventions

• GENETIC

No Results Yet

NCT03678389 | RECRUITING | NA

70 participants

Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-05-09

Completion:

2028-03-01

Conditions

• Pituitary Neoplasm

Interventions

• OTHER

No Results Yet

NCT03657394 | ACTIVE_NOT_RECRUITING | NA

3442 participants

Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-10-17

Completion:

2025-09-01

Conditions

• Hypoxic-Ischemic Encephalopathy
• Birth Asphyxia

Interventions

• OTHER

No Results Yet

NCT03648905 | COMPLETED

89 participants

Clinical Laboratory Evaluation of Chronic Autonomic Failure

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-09-06

Completion:

2026-07-15

Conditions

• Parkinson's Disease
• Multiple System Atrophy
• Autonomic Failure

Interventions

• DRUG

No Results Yet

NCT03647878 | ACTIVE_NOT_RECRUITING

224 participants

Study of Cabozantinib as Monotherapy or in Combination With Nivolumab in Patients With Advanced or Metastatic Renal Cell Carcinoma Under Real-life Clinical Setting in 1st Line Treatment.

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-09-24

Completion:

2027-09-30

Conditions

• Advanced Renal Cell Carcinoma
• Metastatic Renal Cell Carcinoma

No Results Yet

NCT03604991 | SUSPENDED | PHASE2/PHASE3

278 participants

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-05-03

Completion:

2026-12-31

Conditions

• Clinical Stage II Esophageal Adenocarcinoma AJCC v8
• Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Esophageal Adenocarcinoma
• Gastroesophageal Junction Adenocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT03600701 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-11-29

Completion:

2025-07-14

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Refractory Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

Results Available

NCT03581318 | RECRUITING

5000 participants

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-07-12

Completion:

2028-04-01

Conditions

• Normal and Abnormal Cardiovascular Physiology

No Results Yet

NCT03547973 | ACTIVE_NOT_RECRUITING | PHASE2

502 participants

Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-08-13

Completion:

2030-04-30

Conditions

• Metastatic Urothelial Cancer

Interventions

• DRUG

No Results Yet

NCT03538600 | RECRUITING

600 participants

Sample Collection From Healthy Volunteers for Assay Optimization

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-06-28

Completion:

2043-06-30

Conditions

• Healthy Volunteers

No Results Yet

NCT03537794 | RECRUITING

45 participants

Characterizing Synaptic Density in Treatment Resistant Depression

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2025-08-22

Completion:

2028-12-31

Conditions

• Treatment Resistant Depression
• Depression - Major Depressive Disorder

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03520660 | ACTIVE_NOT_RECRUITING | PHASE4

121 participants

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-10-19

Completion:

2032-12-31

Conditions

• Diabetes Mellitus
• Hepatitis C, Chronic
• Cardiovascular Diseases

Interventions

• DRUG

No Results Yet

NCT03520647 | RECRUITING | PHASE2

56 participants

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-02-19

Completion:

2027-06-01

Conditions

• Severe Aplastic Anemia (SAA)
• Hypo-Plastic Myelodysplastic Syndrome (MDS)
• Paroxysmal Nocturnal Hemoglobinuria (PNH)

Interventions

• DRUG
• OTHER

No Results Yet

NCT03510442 | RECRUITING

2000 participants

Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-05-21

Completion:

2050-01-01

Conditions

• Still's Disease, Adult-Onset
• Systemic Inflammation
• Arthritis
• Autoinflammatory Syndrome

No Results Yet

NCT03500315 | COMPLETED | NA

207 participants

HOPE in Action Prospective Multicenter, Clinical Trial of Deceased HIVD+ Kidney Transplants for HIV+ Recipients

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-04-19

Completion:

2022-09-30

Conditions

• Hiv

Interventions

• OTHER

Results Available

NCT03486873 | RECRUITING | PHASE3

3500 participants

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-08-21

Completion:

2043-08-04

Conditions

• Solid Tumors
• Hematologic Malignancies

Interventions

• DRUG
• BIOLOGICAL

No Results Yet