Clinical Trials

NCT03801434 | ACTIVE_NOT_RECRUITING | PHASE2

8 participants

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-11-15

Completion:

2029-02-28

Conditions

• BCR-JAK2 Fusion Protein Expression
• Blasts 20 Percent or Less of Peripheral Blood White Cells
• Blasts More Than 5 Percent of Bone Marrow Nucleated Cells
• Blasts More Than 5 Percent of Peripheral Blood White Cells
• Blasts Under 20 Percent of Bone Marrow Nucleated Cells
• Chronic Eosinophilic Leukemia, Not Otherwise Specified
• Eosinophilia
• Hepatomegaly
• Hypereosinophilic Syndrome
• JAK2 Gene Mutation
• Splenomegaly
• TEL-JAK2 Fusion Protein Expression

Interventions

• DRUG

No Results Yet

NCT03773523 | ACTIVE_NOT_RECRUITING | NA

30 participants

Neuromodulation and Cognitive Training in Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-08-01

Completion:

2027-05-15

Conditions

• Opioid-use Disorder
• Opioid Dependence
• Opioid Abuse

Interventions

• DEVICE

No Results Yet

NCT03766971 | SUSPENDED | PHASE2

160 participants

Influence of Tobacco Use on Cannabis Use

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2020-02-01

Completion:

2027-11-30

Conditions

• Cannabis Use
• Tobacco Use

Interventions

• BEHAVIORAL
• DRUG

No Results Yet

NCT03762733 | ENROLLING_BY_INVITATION

500 participants

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2022-01-04

Completion:

2028-12-29

Conditions

• Breast Cancer
• Ovarian Cancer
• Uterine Cancer

No Results Yet

NCT03755895 | COMPLETED | PHASE2

68 participants

Contribution of Hypnosis to Anxiety and Pain in Brachytherapy Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-11-02

Completion:

2022-05-17

Conditions

• Cancer
• Brachytherapy

Interventions

• OTHER
• DRUG

No Results Yet

NCT03752697 | COMPLETED

30 participants

Metacognition in Neurological Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-12-13

Completion:

2023-03-30

Conditions

• Brain Injuries

Interventions

• BEHAVIORAL

No Results Yet

NCT03733093 | COMPLETED

1377 participants

PREVAIL VIII: A CoHOrt Clinical, Viral, and ImmuNOlogic Monitoring Study of People Living With Retroviral Infection in Liberia (HONOR)

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2019-08-22

Completion:

2025-12-31

Conditions

• HIV

No Results Yet

NCT03729115 | RECRUITING | NA

400 participants

A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-05-30

Completion:

2028-12-31

Conditions

• Breast Cancer

Interventions

• PROCEDURE

No Results Yet

NCT03727555 | NOT_YET_RECRUITING | NA

30 participants

IT and IV Lentiviral Gene Therapy for X-ALD

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2027-06-01

Completion:

2028-05-31

Conditions

• X-linked Adrenoleukodystrophy

Interventions

• GENETIC

No Results Yet

NCT03725670 | NOT_YET_RECRUITING | NA

10 participants

Direct Lentiviral Injection Gene Therapy for MLD

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2027-05-31

Completion:

2028-06-01

Conditions

• Metachromatic Leukodystrophy (MLD)

Interventions

• GENETIC

No Results Yet

NCT03678389 | RECRUITING | NA

70 participants

Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-05-09

Completion:

2028-03-01

Conditions

• Pituitary Neoplasm

Interventions

• OTHER

No Results Yet

NCT03657394 | ACTIVE_NOT_RECRUITING | NA

3442 participants

Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2022-10-17

Completion:

2025-09-01

Conditions

• Hypoxic-Ischemic Encephalopathy
• Birth Asphyxia

Interventions

• OTHER

No Results Yet

NCT03648905 | COMPLETED

89 participants

Clinical Laboratory Evaluation of Chronic Autonomic Failure

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-09-06

Completion:

2026-07-15

Conditions

• Parkinson's Disease
• Multiple System Atrophy
• Autonomic Failure

Interventions

• DRUG

No Results Yet

NCT03647878 | ACTIVE_NOT_RECRUITING

224 participants

Study of Cabozantinib as Monotherapy or in Combination With Nivolumab in Patients With Advanced or Metastatic Renal Cell Carcinoma Under Real-life Clinical Setting in 1st Line Treatment.

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-09-24

Completion:

2027-09-30

Conditions

• Advanced Renal Cell Carcinoma
• Metastatic Renal Cell Carcinoma

No Results Yet

NCT03604991 | SUSPENDED | PHASE2/PHASE3

278 participants

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-05-03

Completion:

2026-12-31

Conditions

• Clinical Stage II Esophageal Adenocarcinoma AJCC v8
• Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Esophageal Adenocarcinoma
• Gastroesophageal Junction Adenocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT03600701 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-11-29

Completion:

2025-07-14

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Refractory Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

Results Available

NCT03581318 | RECRUITING

5000 participants

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-07-12

Completion:

2028-04-01

Conditions

• Normal and Abnormal Cardiovascular Physiology

No Results Yet

NCT03547973 | ACTIVE_NOT_RECRUITING | PHASE2

502 participants

Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-08-13

Completion:

2030-04-30

Conditions

• Metastatic Urothelial Cancer

Interventions

• DRUG

No Results Yet

NCT03538600 | RECRUITING

600 participants

Sample Collection From Healthy Volunteers for Assay Optimization

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-06-28

Completion:

2043-06-30

Conditions

• Healthy Volunteers

No Results Yet

NCT03537794 | RECRUITING

45 participants

Characterizing Synaptic Density in Treatment Resistant Depression

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2025-08-22

Completion:

2028-12-31

Conditions

• Treatment Resistant Depression
• Depression - Major Depressive Disorder

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03520660 | ACTIVE_NOT_RECRUITING | PHASE4

121 participants

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-10-19

Completion:

2032-12-31

Conditions

• Diabetes Mellitus
• Hepatitis C, Chronic
• Cardiovascular Diseases

Interventions

• DRUG

No Results Yet

NCT03520647 | RECRUITING | PHASE2

56 participants

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2019-02-19

Completion:

2027-06-01

Conditions

• Severe Aplastic Anemia (SAA)
• Hypo-Plastic Myelodysplastic Syndrome (MDS)
• Paroxysmal Nocturnal Hemoglobinuria (PNH)

Interventions

• DRUG
• OTHER

No Results Yet

NCT03510442 | RECRUITING

2000 participants

Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-05-21

Completion:

2050-01-01

Conditions

• Still's Disease, Adult-Onset
• Systemic Inflammation
• Arthritis
• Autoinflammatory Syndrome

No Results Yet

NCT03481829 | RECRUITING

1500 participants

Early Tracking of Childhood Health Determinants (ETCHED) Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2022-04-14

Completion:

2041-12-31

Conditions

• Diabetes Mellitus
• Obesity
• Fatty Liver

No Results Yet

NCT03449836 | COMPLETED | PHASE3

60 participants

Effects of the Direct Interaction Between Streptococcus Salivarius 24SMBc and Streptococcus Oralis 89a and the Respiratory Epithelium in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-03-01

Completion:

2018-09-30

Conditions

• Allergy

Interventions

• COMBINATION_PRODUCT
• OTHER

No Results Yet

NCT03445988 | COMPLETED | NA

1462 participants

Cognitive Behavioral Therapy and Chronic Pain Self-Management Within the Context of Opioid Reduction: The EMPOWER Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-07-24

Completion:

2023-11-06

Conditions

• Chronic Pain

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT03407079 | RECRUITING | PHASE2

150 participants

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-04-05

Completion:

2027-12-26

Conditions

• Healthy Volunteers
• Overweight

Interventions

• OTHER

No Results Yet

NCT03401385 | ACTIVE_NOT_RECRUITING | PHASE1

890 participants

First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-01-31

Completion:

2028-01-01

Conditions

• Hormone Receptor Positive Breast Cancer
• Triple Negative Breast Cancer
• Non-small Cell Lung Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT03394053 | RECRUITING

2500 participants

The Mechanistic Biology of Primary Immunodeficiency Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-05-30

Completion:

2029-12-31

Conditions

• Primary Immunodeficiency Disorders

No Results Yet

NCT03378856 | RECRUITING

1500 participants

Evaluation of Technological Innovation in Radiotherapy

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2017-11-01

Completion:

2040-10-31

Conditions

• Cancer
• Radiotherapy Side Effect

No Results Yet

NCT03374215 | RECRUITING

1150 participants

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2017-12-14

Completion:

2026-12-31

Conditions

• Adrenal Gland Neoplasm
• Hypertension
• Bone Diseases, Metabolic
• Cardiovascular Disease
• Hyperinsulinemia

No Results Yet

NCT03366168 | RECRUITING

250 participants

Taste Bud-Derived Stem Cells in Humans

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2017-12-18

Completion:

2026-12-31

Conditions

• Diabetes

No Results Yet

NCT03366116 | RECRUITING | PHASE1

75 participants

5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-11-05

Completion:

2026-09-30

Conditions

• Neoplasms
• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT03354416 | RECRUITING

10000 participants

Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-02-26

Completion:

2030-12-31

Conditions

• Prostatic Cancer
• Prostatic Neoplams
• Prostatic Hyperplasia
• Prostate Cancer
• Cancer Of Prostate

No Results Yet

NCT03351764 | COMPLETED | NA

83 participants

Development of Non-Invasive Brain Stimulation Techniques

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-01

Start Date:

2018-01-11

Completion:

2025-12-15

Conditions

• Normal Physiology

Interventions

• DEVICE

No Results Yet

NCT03307317 | RECRUITING

200 participants

Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2018-08-30

Completion:

2030-02-01

Conditions

• Developmental Delay

No Results Yet

NCT03307304 | RECRUITING

300 participants

Investigations of Juvenile Neuronal Ceroid Lipofuscinosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2017-11-27

Completion:

2050-12-31

Conditions

• Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)
• Batten Disease

No Results Yet

NCT03304665 | RECRUITING

2000 participants

Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2017-11-01

Completion:

2027-04-26

Conditions

• Healthy Volunteer

No Results Yet

NCT03300830 | RECRUITING

280 participants

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2017-12-20

Completion:

2037-06-07

Conditions

• Human Immunodeficiency Virus
• Castleman's Disease
• Kaposi's Sarcoma
• Viral-Associated Cancer

No Results Yet

NCT03269578 | RECRUITING

3000 participants

Sample Collection and Tracking for the Developmental Therapeutics Clinic

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-01

Start Date:

2017-08-28

Completion:

2027-05-23

Conditions

• Neoplasms
• Lymphoma

No Results Yet