Clinical Trials Updated in 2026

NCT06819891 | RECRUITING | PHASE3

425 participants

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-05-12
Completion:: 2028-12-31

Conditions

Moderately to Severely Active Crohns Disease

Interventions

DRUG

No Results Yet

NCT06817785 | COMPLETED | NA

45 participants

Soft Lens Study: Biomedics 1 Day Extra Sphere and Clariti 1 Day Sphere

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-01-24
Completion:: 2025-02-25

Conditions

Myopia

Interventions

DEVICE

Results Available

NCT06811402 | NOT_YET_RECRUITING | NA

26 participants

Combinaison of Virtual Reality and Rehabilitation to Improve Muscle Function, Exercise Tolerance, Exertional Symptoms and Dyspnea in Patients With Chronic Respiratory Disease: a Randomized Cross-over Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-09-01
Completion:: 2027-03-31

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

OTHER

No Results Yet

NCT06808789 | RECRUITING

32000 participants

Mapping Snakebite Risk in Ghana and Rwanda

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-08-01
Completion:: 2027-01-31

Conditions

Snakebite
Snake Envenomation

No Results Yet

NCT06806098 | COMPLETED | NA

1555 participants

Cessation Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-05
Completion:: 2025-11-17

Conditions

Tobacco Use Cessation

Interventions

BEHAVIORAL

No Results Yet

NCT06805695 | RECRUITING

13 participants

Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-23
Completion:: 2041-07-31

Conditions

Ornithine Transcarbamylase Deficiency
Ornithine Transcarbamylase Deficiency Disease
Urea Cycle Disorders, Inborn

Interventions

OTHER

No Results Yet

NCT06800313 | RECRUITING | PHASE1/PHASE2

190 participants

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-02-06
Completion:: 2028-07-11

Conditions

Metastatic Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06799494 | RECRUITING | PHASE4

100 participants

HPV Vaccine Reduced Dose

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-08-06
Completion:: 2028-09-30

Conditions

HPV

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06785376 | RECRUITING | NA

480 participants

P3 Trial: Estimating the Impact of a Multilevel, Multicomponent Intervention to Increase Uptake of HIV Testing and Biomedical HIV Prevention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-19
Completion:: 2028-02-28

Conditions

HIV Testing
PrEP Uptake

Interventions

BEHAVIORAL

No Results Yet

NCT06781294 | ACTIVE_NOT_RECRUITING | NA

343 participants

SIRAKI 02 Posthoc Analysis.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-10-01
Completion:: 2026-11-01

Conditions

Cardiac Surgery Requiring Cardiopulmonary Bypass
Acute Kidney Injury
Chronic Kidney Disease(CKD)
Kidney Failure, Acute

Interventions

DEVICE

No Results Yet

NCT06778564 | RECRUITING | PHASE3

250 participants

Stratification and Treatment in Early Psychosis Study - ENHANCE

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-08-31
Completion:: 2028-02-29

Conditions

Psychosis
First Episode Psychosis
Psychotic Disorders
Psychotic Episode

Interventions

DRUG
OTHER

No Results Yet

NCT06771661 | COMPLETED

46 participants

Parents' Experience of Child Loss During Pregnancy or Birth

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-02
Completion:: 2025-07-17

Conditions

Stillbirth and Fetal Death
Miscarriages
Experience

Interventions

OTHER

No Results Yet

NCT06755567 | RECRUITING

750 participants

Application of MRI Radiomics Features in Neoadjuvant Therapy of Head and Neck Squamous Cell Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-25
Completion:: 2026-12-31

Conditions

Head and Neck Cancer
Neoadjuvant Therapy
Immunotherapy
Chemotherapy
Pathologic Complete Response

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06747117 | RECRUITING

300 participants

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-05-18
Completion:: 2028-06-30

Conditions

Lower Extremity Acute Limb Ischemia
LE ALI

Interventions

DEVICE

No Results Yet

NCT06744790 | COMPLETED

320 participants

Advanced Prediction of Respiratory Depression Episode Using the Linshom Continuous Predictive Respiratory Sensor

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2023-06-21
Completion:: 2025-04-28

Conditions

Post Surgical Respiratory Failure
Respiratory Complication

Interventions

DEVICE

No Results Yet

NCT06744335 | COMPLETED

1283 participants

Prospective Observational Multicenter Study of Patients With AH and CKD Markers in Kazakhstan (PROGRESS-CKD)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-01-20
Completion:: 2026-08-20

Conditions

Rate of CKD Diagnosis in Patients With AH and CKD Markers
Demographic and Clinical Characteristics for Those Patients
Routine Therapy Before and After the Diagnosis of CKD

No Results Yet

NCT06730061 | ACTIVE_NOT_RECRUITING | PHASE3

18 participants

A Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-01-16
Completion:: 2026-12-17

Conditions

Primary Biliary Cholangitis

Interventions

DRUG

No Results Yet

NCT06728137 | COMPLETED

22 participants

Investigation of a New Compression Bandage System Combining Skin Protection, Padding and Compression in One Single Bandage and Comparing to an Existing One-component Bandage.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-01-14
Completion:: 2025-03-03

Conditions

Healthy Volunteers

Results Available

NCT06722846 | RECRUITING

400 participants

Communicating Health Options to Inform Care and Empower Strategic Care Planning (CHOICES): A Multi-layer Randomized Case Vignette Study.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-11-21
Completion:: 2026-08-31

Conditions

Health Options
Strategic Care Planning

Interventions

BEHAVIORAL

No Results Yet

NCT06716307 | COMPLETED | PHASE1

18 participants

A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-02
Completion:: 2025-03-28

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06709573 | RECRUITING | PHASE4

300 participants

Early Versus Late Adjunctive Vasopressin in Septic Shock

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-04-29
Completion:: 2027-05-01

Conditions

Sepsis
Septic Shock

Interventions

DRUG

No Results Yet

NCT06709391 | RECRUITING | NA

90 participants

Fusion or Not - a Study on Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-02-01
Completion:: 2030-12-31

Conditions

Low Back Pain, Mechanical
Degenerative Disc Disease Lumbar

Interventions

PROCEDURE

No Results Yet

NCT06709261 | COMPLETED | NA

32 participants

Safety and Performance of the OTTAVA Robotic System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-02-05
Completion:: 2025-10-20

Conditions

Obesity

Interventions

DEVICE

No Results Yet

NCT06701903 | RECRUITING | PHASE2

570 participants

Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-11-21
Completion:: 2027-10-14

Conditions

Generalized Anxiety Disorder

Interventions

DRUG

No Results Yet

NCT06694454 | SUSPENDED | PHASE1/PHASE2

60 participants

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-09-03
Completion:: 2031-12-31

Conditions

Non-small Cell Lung Cancer (NSCLC)
Carcinoma, Non-Small Cell Lung
Non-Small Cell Lung Carcinoma
Non Small Cell Lung Cancer
Non Small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT06690294 | NOT_YET_RECRUITING

110 participants

Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-09-03
Completion:: 2027-01-30

Conditions

Healthy Volunteer
Obestity

No Results Yet

NCT06687148 | COMPLETED | NA

21 participants

Global Changes Associated With Sacroiliac Joint Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-02-19
Completion:: 2024-02-27

Conditions

Sacroiliac Dysfunction

Interventions

OTHER

No Results Yet

NCT06683378 | RECRUITING | PHASE1

24 participants

A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-07-21
Completion:: 2028-12-31

Conditions

Parkinson's Disease

Interventions

PROCEDURE

No Results Yet

NCT06683365 | RECRUITING | PHASE1

7 participants

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-02-25
Completion:: 2028-12-02

Conditions

Multiple System Atrophy
Parkinsons Disease

Interventions

PROCEDURE

No Results Yet

NCT06676059 | RECRUITING

10000 participants

SMART-r: Substance Monitoring and Active Relapse Tracking Repository

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-09-03
Completion:: 2044-12-31

Conditions

Alcoholism
Substance-Related Disorders

No Results Yet

NCT06672510 | SUSPENDED | NA

118 participants

Safety and Effectiveness of the Akura Thrombectomy System for Use in the Removal of Emboli From the Pulmonary Arteries in Treating Acute Pulmonary Embolism (PE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-01-27
Completion:: 2028-09-30

Conditions

Pulmonary Embolism Acute

Interventions

DEVICE

No Results Yet

NCT06669533 | RECRUITING | NA

420 participants

Use Misoprostol to Optimize Prevention of Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-02-25
Completion:: 2027-11-04

Conditions

Cervical Cancers

Interventions

DRUG

No Results Yet

NCT06664814 | RECRUITING | PHASE2

30 participants

An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Podocyte Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-09-03
Completion:: 2027-11-30

Conditions

Focal Segmental Glomerulosclerosis

Interventions

DRUG

No Results Yet

NCT06664619 | RECRUITING | PHASE3

724 participants

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-12
Completion:: 2026-09-19

Conditions

Asthma

Interventions

DRUG

No Results Yet

NCT06664034 | COMPLETED | NA

42 participants

Intervening on Women's Health for Rural Young Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-01
Completion:: 2025-09-30

Conditions

Cancer
Fertility Issues
Contraception

Interventions

BEHAVIORAL

No Results Yet

NCT06661486 | ACTIVE_NOT_RECRUITING | NA

120 participants

Evidence-based Lifestyle Interventions for the Delay of Cognitive Decline Among Older Singaporeans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-10-01
Completion:: 2027-03-31

Conditions

Non Demented

Interventions

BEHAVIORAL

No Results Yet

NCT06654336 | RECRUITING | PHASE2

162 participants

Study of Recurrence-directed Therapy (RDT) With or Without Androgen-Deprivation Therapy (ADT) In Patients With Radio-recurrent Oligo-metastatic Hormone/Castrate Sensitive Prostate Cancer (romCSPC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-05-06
Completion:: 2031-04-30

Conditions

Prostate Adenocarcinoma
Castration Sensitive Prostate Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT06649812 | RECRUITING | PHASE2

120 participants

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-10-07
Completion:: 2028-09-01

Conditions

High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements
Recurrent Diffuse Large B-Cell Lymphoma
Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified
Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified
Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT06646276 | RECRUITING | PHASE3

530 participants

A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2025-02-25
Completion:: 2028-04-06

Conditions

Extensive-Stage Small Cell Lung Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06635629 | RECRUITING | PHASE2

140 participants

Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2024-12-12
Completion:: 2028-10-01

Conditions

Cushing Syndrome

Interventions

DRUG

No Results Yet