Clinical Trials Updated in 2026

NCT04133636 | ACTIVE_NOT_RECRUITING | PHASE2

208 participants

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-11-07
Completion:: 2027-02-26

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT04119050 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

118 participants

Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-08-15
Completion:: 2025-02-02

Conditions

Warm Autoimmune Hemolytic Anemia

Interventions

DRUG

No Results Yet

NCT04086485 | RECRUITING | PHASE1/PHASE2

56 participants

Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-10-03
Completion:: 2027-07-01

Conditions

Gastroenteropancreatico Tumors
Neuroendocrine Tumors
Neuroendocrine Neoplasms

Interventions

DRUG
DIAGNOSTIC_TEST

No Results Yet

NCT04071236 | SUSPENDED | PHASE1/PHASE2

90 participants

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2020-10-14
Completion:: 2027-04-30

Conditions

Metastatic Castration-Resistant Prostate Carcinoma
Metastatic Malignant Neoplasm in the Bone
Metastatic Malignant Neoplasm in the Lymph Nodes
Stage IVB Prostate Cancer AJCC v8

Interventions

DRUG
PROCEDURE
OTHER
RADIATION

No Results Yet

NCT04061720 | COMPLETED | NA

502 participants

Identifying Effective Treatment for Veterans Unwilling to Quit Smoking

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-11-12
Completion:: 2025-09-26

Conditions

Tobacco Dependence
Veterans

Interventions

BEHAVIORAL

Results Available

NCT04055077 | COMPLETED | NA

176 participants

Influence of HFNO on Spontaneous Breathing Support in Patients of Different ASA Risk During Moderate Multimodal Analgo-sedation for Pars Plana Vitrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2022-06-01
Completion:: 2023-06-01

Conditions

Hypoxia
Pars Plana Vitrectomy
Respiratory Complications

Interventions

DEVICE

No Results Yet

NCT04044001 | COMPLETED | PHASE1/PHASE2

78 participants

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-11-15
Completion:: 2022-03-03

Conditions

Pulmonary Tuberculoses
Other Specified Pulmonary Tuberculosis

Interventions

DRUG

Results Available

NCT04033445 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

1064 participants

A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-09-26
Completion:: 2023-09-19

Conditions

Ulcerative Colitis

Interventions

DRUG

Results Available

NCT04006522 | ACTIVE_NOT_RECRUITING | PHASE2

46 participants

89Zr-DFO-Atezolizumab ImmunoPET/CT in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-10-02
Completion:: 2026-08-06

Conditions

Renal Cell Carcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03995966 | ACTIVE_NOT_RECRUITING | NA

16 participants

A Clinical Trial for Self-Injurious Behavior

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-06-04
Completion:: 2025-09-09

Conditions

Self-Injurious Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT03988595 | ACTIVE_NOT_RECRUITING | PHASE1

54 participants

Exercise Treatment With Standard Therapy for Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-06-12
Completion:: 2027-08-01

Conditions

Hormone Receptor Positive Metastatic Breast Cancer

Interventions

OTHER

No Results Yet

NCT03977753 | RECRUITING | PHASE4

162 participants

Randomized, Placebo-controlled, Double Blind Study to Evaluate the Efficacy of 2LVERU®JUNIOR and 2LVERU® on the Treatment of Warts

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2020-02-17
Completion:: 2028-12-16

Conditions

Common Wart
Flat Wart
Plantar Wart

Interventions

DRUG

No Results Yet

NCT03973281 | COMPLETED | NA

420 participants

EASE: The Materna Prep Pivotal Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-12-11
Completion:: 2026-07-30

Conditions

Vaginal Delivery
Pelvic Organ Prolapse

Interventions

DEVICE
OTHER

No Results Yet

NCT03948724 | COMPLETED | NA

412 participants

Impact of Therapeutic Patient Education on the Toxicity of Immune Checkpoint Inhibitors in Oncology

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-12-11
Completion:: 2023-08-04

Conditions

Therapeutic Patient Education
Immune Checkpoint Inhibitors
Melanoma
Advanced Non-small Cell Lung Cancer
Renal Cell Carcinoma
Head and Neck Cancer
Immune-related Adverse Event

Interventions

BEHAVIORAL

Results Available

NCT03944226 | COMPLETED | NA

1 participants

Is Dietary Nitrate Effective in Reducing Aerobic Glycolysis in Breast Cancer?

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-08-01
Completion:: 2022-11-28

Conditions

Malignant Breast Tissue Neoplasm

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT03937817 | RECRUITING

300 participants

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-09-25
Completion:: 2029-03-31

Conditions

Alpha and Beta Thalassemia
Sickle Cell Disease
Malaria
Human Physiology

No Results Yet

NCT03937804 | COMPLETED

83 participants

New Approaches for Empowering Studies of Asthma in Populations of African Descent

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-09-23
Completion:: 2021-07-15

Conditions

Asthma

No Results Yet

NCT03923205 | COMPLETED | NA

28 participants

Assessing the Effects of a Buckwheat Beverage on Postprandial Glucose Metabolism on Healthy and T2D Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-03-07
Completion:: 2022-03-31

Conditions

Healthy
Type2 Diabetes

Interventions

OTHER

No Results Yet

NCT03922724 | ACTIVE_NOT_RECRUITING | PHASE2

91 participants

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-04-18
Completion:: 2027-06-01

Conditions

Peripheral T-cell Lymphomas
Lymphoproliferative Disorders
Immune System Diseases

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03910452 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

4 participants

Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-10-28
Completion:: 2034-06-15

Conditions

Chronic Granulomatous Disease

Interventions

DRUG
RADIATION
BIOLOGICAL

No Results Yet

NCT03895645 | ENROLLING_BY_INVITATION

1000 participants

Connors Protocol for the Management and Use of Stored Human Specimens (Stored Human Specimens)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2026-09-03
Completion:: 2029-12-31

Conditions

Healthy Volunteer Samples

No Results Yet

NCT03827343 | ACTIVE_NOT_RECRUITING

500 participants

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-01-23
Completion:: 2026-12-31

Conditions

Macrophage Activation Syndrome
Primary Hemophagocytic Lymphohistiocytosis

No Results Yet

NCT03805919 | RECRUITING

500 participants

Men at High Genetic Risk for Prostate Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-03-27
Completion:: 2029-01-01

Conditions

Prostatic Neoplasms

No Results Yet

NCT03793166 | ACTIVE_NOT_RECRUITING | PHASE3

1175 participants

Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-06-07
Completion:: 2028-01-25

Conditions

Clear Cell Renal Cell Carcinoma
Metastatic Malignant Neoplasm in the Bone
Metastatic Malignant Neoplasm in the Lymph Nodes
Metastatic Malignant Neoplasm in the Soft Tissue
Metastatic Malignant Neoplasm in the Viscera
Rhabdoid Tumor of the Kidney
Sarcomatoid Renal Cell Carcinoma
Stage III Renal Cell Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT03776162 | ACTIVE_NOT_RECRUITING | NA

150 participants

A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2021-08-30
Completion:: 2027-07-31

Conditions

Anterior Cruciate Ligament Tear

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT03745339 | RECRUITING

150 participants

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-06-07
Completion:: 2026-10-01

Conditions

Opioid-Related Disorders
Drug Addiction

No Results Yet

NCT03743766 | COMPLETED | PHASE2

43 participants

Nivolumab, BMS-936558 in Combination With Relatlimab, BMS-986016 in Patients With Metastatic Melanoma Naïve to Prior Immunotherapy in the Metastatic Setting

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-03-29
Completion:: 2024-07-03

Conditions

Melanoma

Interventions

DRUG

Results Available

NCT03739814 | RECRUITING | PHASE2

84 participants

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-05-08
Completion:: 2027-02-01

Conditions

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Recurrent B Acute Lymphoblastic Leukemia
Refractory B Acute Lymphoblastic Leukemia

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT03737214 | ACTIVE_NOT_RECRUITING | PHASE3

107 participants

A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2018-12-18
Completion:: 2029-08-31

Conditions

Fabry Disease

Interventions

DRUG

No Results Yet

NCT03733093 | COMPLETED

1377 participants

PREVAIL VIII: A CoHOrt Clinical, Viral, and ImmuNOlogic Monitoring Study of People Living With Retroviral Infection in Liberia (HONOR)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-08-22
Completion:: 2025-12-31

Conditions

HIV

No Results Yet

NCT03684317 | WITHDRAWN

0 participants

Primary Dependence to Analgesic Drugs

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-06-01
Completion:: 2023-04-30

Conditions

Addiction

No Results Yet

NCT03683251 | RECRUITING | PHASE3

1000 participants

Extension Study for the Port Delivery System With Ranibizumab (Portal)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2018-09-20
Completion:: 2029-12-31

Conditions

Neovascular Age-Related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT03678389 | RECRUITING | NA

70 participants

Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-05-09
Completion:: 2028-03-01

Conditions

Pituitary Neoplasm

Interventions

OTHER

No Results Yet

NCT03652428 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

24 participants

Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-04-02
Completion:: 2026-12-31

Conditions

Locally Advanced Pancreatic Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT03596645 | ACTIVE_NOT_RECRUITING | PHASE3

84 participants

A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2018-10-29
Completion:: 2023-11-21

Conditions

Colitis, Ulcerative

Interventions

DRUG

Results Available

NCT03535298 | ACTIVE_NOT_RECRUITING | PHASE4

800 participants

Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2019-01-03
Completion:: 2027-07-30

Conditions

Multiple Sclerosis, Relapsing-Remitting

Interventions

DRUG

No Results Yet

NCT03534245 | COMPLETED

775 participants

Investigating Vector-Borne Determinants of Aedes Transmitted Arboviral Infections in Cambodia: An Observational Longitudinal Cohort Study in Children

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2018-07-01
Completion:: 2022-01-25

Conditions

Dengue Fever

No Results Yet

NCT03505320 | ACTIVE_NOT_RECRUITING | PHASE2

143 participants

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2018-06-29
Completion:: 2027-06-30

Conditions

Pharmacokinetics of Zolbetuximab
Gastric Cancer
Gastro-esophageal Junction (GEJ) Cancer
Pharmacokinetics of Oxaliplatin
Pharmacokinetics of Fluorouracil Bolus (5-FU)

Interventions

DRUG

No Results Yet

NCT03480633 | RECRUITING

3000 participants

Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-31
Start Date:: 2016-04-07
Completion:: 2028-10-31

Conditions

Heart Failure With Normal Ejection Fraction
Heart Failure With Reduced Ejection Fraction
Heart Failure, Right Sided
Heart Failure With Mid Range Ejection Fraction
Cardiovascular Risk Factor

No Results Yet

NCT03466411 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

1409 participants

A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-31
Start Date:: 2018-04-13
Completion:: 2023-10-20

Conditions

Crohn's Disease

Interventions

DRUG

Results Available