Clinical Trials

NCT06683755 | RECRUITING | PHASE1/PHASE2

30 participants

Phase I/IIa Dose Finding Study of Triplet Regimen of Relatlimab Ipilimumab and NIvolumab in First Line Therapy of Metastatic Melanoma (TRINITY)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-31

Completion:

2030-08-16

Conditions

• Melanoma

Interventions

• DRUG

No Results Yet

NCT06682780 | RECRUITING | PHASE1/PHASE2

320 participants

A Phase I/II Study of LM-2417 in Subjects With Advanced Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-09-17

Completion:

2028-12-25

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06680830 | RECRUITING | PHASE2

150 participants

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-01-17

Completion:

2027-12-31

Conditions

• Parkinson Disease
• Parkinson
• Idiopathic Parkinson Disease
• Early Parkinson Disease (Early PD)
• Parkinson Disease, Idiopathic

Interventions

• DRUG
• OTHER

No Results Yet

NCT06667908 | RECRUITING | PHASE2

130 participants

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-06

Completion:

2028-12-31

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT06667700 | RECRUITING | PHASE3

3082 participants

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-02

Completion:

2031-01-26

Conditions

• Coronavirus Disease (COVID-19)

Interventions

• DRUG

No Results Yet

NCT06667076 | RECRUITING | PHASE2

480 participants

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-16

Completion:

2029-05-23

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT06666985 | RECRUITING | PHASE4

700 participants

Intrathecal Morphine for Postoperative Analgesia in Major Laparoscopic Abdominal Surgery, a IMPACT-Scope Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-16

Completion:

2026-09-30

Conditions

• Patients Undergoing Major Laparoscopic Abdominal Surgery

Interventions

• DRUG

No Results Yet

NCT06664788 | RECRUITING | NA

108 participants

A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-04-16

Completion:

2026-09-28

Conditions

• Hemostasis
• Hemostatic Techniques

Interventions

• DEVICE

No Results Yet

NCT06663332 | RECRUITING | PHASE3

196 participants

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-29

Completion:

2031-12-12

Conditions

• Crohns Disease
• Colitis, Ulcerative
• Arthritis, Psoriatic
• Arthritis, Juvenile

Interventions

• DRUG

No Results Yet

NCT06663319 | RECRUITING | PHASE1

260 participants

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-15

Completion:

2028-02-25

Conditions

• Colorectal Neoplasms
• Gastrointestinal Neoplasms

Interventions

• DRUG

No Results Yet

NCT06662786 | RECRUITING | PHASE3

1000 participants

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-18

Completion:

2028-12-15

Conditions

• Colorectal Neoplasms

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06660563 | ACTIVE_NOT_RECRUITING | PHASE1

19 participants

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-22

Completion:

2026-01-19

Conditions

• Lymphoma, Non-Hodgkin

Interventions

• DRUG

No Results Yet

NCT06659536 | RECRUITING | NA

53 participants

Cefar URO - Symptomatic Treatment of Overactive Bladder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-01-19

Completion:

2026-10-31

Conditions

• Overactive Bladder (OAB)
• Refractory Overactive Bladder
• Urinary Urgency and Frequency

Interventions

• DEVICE

No Results Yet

NCT06656884 | ACTIVE_NOT_RECRUITING

524 participants

FARAPULSE Workflow Assessment Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2025-05-06

Completion:

2027-02-15

Conditions

• Atrial Fibrillation (AF)

No Results Yet

NCT06655883 | RECRUITING | PHASE3

300 participants

A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-10-09

Completion:

2027-06-24

Conditions

• Insomnia

Interventions

• DRUG

No Results Yet

NCT06651229 | RECRUITING | PHASE1

155 participants

A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-03-21

Completion:

2027-08-05

Conditions

• Leukemia, Myeloid, Acute
• Myelodysplastic Neoplasms

Interventions

• DRUG

No Results Yet

NCT06648889 | RECRUITING | PHASE2

28 participants

Isatuximab in Adult Patients With Cytologic or Molecular Relapsed/Refractory CD38 Positive T-cell Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-22

Completion:

2029-06-30

Conditions

• T-ALL

Interventions

• DRUG

No Results Yet

NCT06646289 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-10

Completion:

2030-10-24

Conditions

• X-Linked Retinitis Pigmentosa

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06642246 | RECRUITING | NA

10 participants

Sleep Promotion and Pediatric Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-02-16

Completion:

2026-11-30

Conditions

• Insufficient Sleep
• Hypertension

Interventions

• BEHAVIORAL

No Results Yet

NCT06638892 | RECRUITING | NA

1000 participants

Using PrEP, Doing It for Ourselves

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-02-13

Completion:

2029-06-30

Conditions

• HIV Prevention
• PrEP

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06637423 | RECRUITING | PHASE1/PHASE2

32 participants

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-20

Completion:

2029-03-14

Conditions

• Non-Muscle Invasive Bladder Cancer

Interventions

• DRUG

No Results Yet

NCT06636721 | NOT_YET_RECRUITING | NA

16 participants

Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-10-01

Completion:

2027-05-01

Conditions

• Lung Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT06634576 | COMPLETED | NA

40 participants

Assessing the Reliability of Smooth Pursuit Across Various Neck Postures Using a Custom Ocular Motor Detection System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-04-03

Completion:

2025-12-31

Conditions

• Ocular Motor Detectation
• Vestibular
• Cervicogenic Dizziness
• Oculomotor System

Interventions

• DEVICE
• OTHER

No Results Yet

NCT06631638 | RECRUITING | NA

118 participants

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-10-24

Completion:

2027-12-31

Conditions

• Osteoarthritis
• Traumatic Arthritis
• Rheumatoid Arthritis
• Congential Hip Dysplasia
• Avascular Necrosis of the Femoral Head
• Certain Cases of Ankylosis

Interventions

• DEVICE

No Results Yet

NCT06630676 | COMPLETED | NA

288 participants

The Ability of Chronic Pain Patients to Self-diagnose Their Chief Source of Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-16

Completion:

2026-05-08

Conditions

• Chronic Low Back Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT06618001 | ACTIVE_NOT_RECRUITING | PHASE1

64 participants

A Study of JNJ-89853413 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-01-14

Completion:

2026-11-16

Conditions

• Leukemia, Myeloid, Acute
• Myelodysplastic Neoplasms

Interventions

• DRUG

No Results Yet

NCT06604715 | ACTIVE_NOT_RECRUITING | PHASE1

17 participants

A Study of JNJ-87562761 in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-19

Completion:

2027-11-03

Conditions

• Relapsed or Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06600191 | RECRUITING | NA

10 participants

Capstan Medical TMVR Study: FIH

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-02-24

Completion:

2026-12-31

Conditions

• Mitral Regurgitation

Interventions

• DEVICE

No Results Yet

NCT06598735 | RECRUITING | PHASE1

290 participants

A Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Initial Efficacy of HRS-4508 Monotherapy in Patients With Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-11-05

Completion:

2027-12-30

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06596694 | RECRUITING | PHASE1/PHASE2

180 participants

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-11-03

Completion:

2028-12-07

Conditions

• Gastrointestinal Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT06596252 | ACTIVE_NOT_RECRUITING | PHASE3

308 participants

Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-05-21

Completion:

2026-12-31

Conditions

• Eosinophilic Esophagitis

Interventions

• DRUG

No Results Yet

NCT06589804 | RECRUITING | PHASE3

158 participants

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-03-27

Completion:

2029-11-30

Conditions

• Metastatic Head and Neck Squamous Cell Carcinoma
• Metastatic Hypopharyngeal Squamous Cell Carcinoma
• Metastatic Laryngeal Squamous Cell Carcinoma
• Metastatic Oral Cavity Squamous Cell Carcinoma
• Metastatic Oropharyngeal Squamous Cell Carcinoma
• Recurrent Head and Neck Squamous Cell Carcinoma
• Recurrent Hypopharyngeal Squamous Cell Carcinoma
• Recurrent Laryngeal Squamous Cell Carcinoma
• Recurrent Neck Squamous Cell Carcinoma of Unknown Primary
• Recurrent Oral Cavity Squamous Cell Carcinoma
• Recurrent Oropharyngeal Squamous Cell Carcinoma
• Refractory Head and Neck Squamous Cell Carcinoma
• Refractory Hypopharyngeal Squamous Cell Carcinoma
• Refractory Laryngeal Squamous Cell Carcinoma
• Refractory Oral Cavity Squamous Cell Carcinoma
• Refractory Oropharyngeal Squamous Cell Carcinoma
• Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8
• Stage IV Hypopharyngeal Carcinoma AJCC v8
• Stage IV Laryngeal Cancer AJCC v8
• Stage IV Lip and Oral Cavity Cancer AJCC v8
• Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8

Interventions

• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT06585306 | COMPLETED | NA

864 participants

High-flow Nasal Oxygen Therapy in Obese Patients Undergoing Sedativegastrointestinal Endoscopy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-10-23

Completion:

2026-04-20

Conditions

• Hypoxia
• Obesity
• Gastrostomy

Interventions

• BEHAVIORAL

No Results Yet

NCT06582381 | COMPLETED | NA

30 participants

Evaluation of Biomarkers for Predicting Macronutrient Intake

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-12-06

Completion:

2026-04-28

Conditions

• Glucose Metabolism
• Amino Acid Metabolism

Interventions

• OTHER

No Results Yet

NCT06580405 | NOT_YET_RECRUITING | NA

13 participants

A Feasibility Study to Evaluate the Safety of the KNP-1000 Apheresis System in Severe Preeclampsia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2026-10-01

Completion:

2027-08-31

Conditions

• Pre-Eclampsia, Severe

Interventions

• DEVICE

No Results Yet

NCT06579794 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2026-08-28

No Results Yet

NCT06578624 | RECRUITING | PHASE1/PHASE2

70 participants

Safety and Preliminary Efficacy of SA53-OS in Patients With Locally Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-03-10

Completion:

2026-12-31

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06577025 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-08-20

Completion:

2030-09-02

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06566885 | ACTIVE_NOT_RECRUITING

125 participants

Real-world Study Assessing Efficacy of TezepeLumaB in Patients With Severe Asthma Regardless of Phenotype in Russia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2024-09-10

Completion:

2026-09-30

Conditions

• Severe Asthma

No Results Yet

NCT06566664 | ENROLLING_BY_INVITATION | NA

150 participants

Peripheral Neurostimulation for Nerve Block Placement

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2025-07-23

Completion:

2027-07-30

Conditions

• Pain Syndrome
• Pain Management

Interventions

• DEVICE

No Results Yet