Clinical Trials Updated in 2026

NCT06662786 | RECRUITING | PHASE3

1000 participants

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-18
Completion:: 2028-12-15

Conditions

Colorectal Neoplasms

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06660563 | ACTIVE_NOT_RECRUITING | PHASE1

19 participants

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-22
Completion:: 2026-01-19

Conditions

Lymphoma, Non-Hodgkin

Interventions

DRUG

No Results Yet

NCT06659536 | RECRUITING | NA

53 participants

Cefar URO - Symptomatic Treatment of Overactive Bladder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-01-19
Completion:: 2026-10-31

Conditions

Overactive Bladder (OAB)
Refractory Overactive Bladder
Urinary Urgency and Frequency

Interventions

DEVICE

No Results Yet

NCT06656884 | ACTIVE_NOT_RECRUITING

524 participants

FARAPULSE Workflow Assessment Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-05-06
Completion:: 2027-02-15

Conditions

Atrial Fibrillation (AF)

No Results Yet

NCT06655883 | RECRUITING | PHASE3

300 participants

A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-10-09
Completion:: 2027-06-24

Conditions

Insomnia

Interventions

DRUG

No Results Yet

NCT06651229 | RECRUITING | PHASE1

155 participants

A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-21
Completion:: 2027-08-05

Conditions

Leukemia, Myeloid, Acute
Myelodysplastic Neoplasms

Interventions

DRUG

No Results Yet

NCT06648889 | RECRUITING | PHASE2

28 participants

Isatuximab in Adult Patients With Cytologic or Molecular Relapsed/Refractory CD38 Positive T-cell Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-22
Completion:: 2029-06-30

Conditions

T-ALL

Interventions

DRUG

No Results Yet

NCT06646289 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-10
Completion:: 2030-10-24

Conditions

X-Linked Retinitis Pigmentosa

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT06642246 | RECRUITING | NA

10 participants

Sleep Promotion and Pediatric Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-02-16
Completion:: 2026-11-30

Conditions

Insufficient Sleep
Hypertension

Interventions

BEHAVIORAL

No Results Yet

NCT06638892 | RECRUITING | NA

1000 participants

Using PrEP, Doing It for Ourselves

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-02-13
Completion:: 2029-06-30

Conditions

HIV Prevention
PrEP

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06637423 | RECRUITING | PHASE1/PHASE2

32 participants

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-12-20
Completion:: 2029-03-14

Conditions

Non-Muscle Invasive Bladder Cancer

Interventions

DRUG

No Results Yet

NCT06636721 | NOT_YET_RECRUITING | NA

16 participants

Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-10-01
Completion:: 2027-05-01

Conditions

Lung Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06634576 | COMPLETED | NA

40 participants

Assessing the Reliability of Smooth Pursuit Across Various Neck Postures Using a Custom Ocular Motor Detection System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-03
Completion:: 2025-12-31

Conditions

Ocular Motor Detectation
Vestibular
Cervicogenic Dizziness
Oculomotor System

Interventions

DEVICE
OTHER

No Results Yet

NCT06631638 | RECRUITING | NA

118 participants

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-10-24
Completion:: 2027-12-31

Conditions

Osteoarthritis
Traumatic Arthritis
Rheumatoid Arthritis
Congential Hip Dysplasia
Avascular Necrosis of the Femoral Head
Certain Cases of Ankylosis

Interventions

DEVICE

No Results Yet

NCT06630676 | COMPLETED | NA

288 participants

The Ability of Chronic Pain Patients to Self-diagnose Their Chief Source of Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-16
Completion:: 2026-05-08

Conditions

Chronic Low Back Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06618001 | ACTIVE_NOT_RECRUITING | PHASE1

64 participants

A Study of JNJ-89853413 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-01-14
Completion:: 2026-11-16

Conditions

Leukemia, Myeloid, Acute
Myelodysplastic Neoplasms

Interventions

DRUG

No Results Yet

NCT06604715 | ACTIVE_NOT_RECRUITING | PHASE1

17 participants

A Study of JNJ-87562761 in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-12-19
Completion:: 2027-11-03

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06600191 | RECRUITING | NA

10 participants

Capstan Medical TMVR Study: FIH

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-24
Completion:: 2026-12-31

Conditions

Mitral Regurgitation

Interventions

DEVICE

No Results Yet

NCT06598735 | RECRUITING | PHASE1

290 participants

A Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Initial Efficacy of HRS-4508 Monotherapy in Patients With Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-11-05
Completion:: 2027-12-30

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT06596694 | RECRUITING | PHASE1/PHASE2

180 participants

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-11-03
Completion:: 2028-12-07

Conditions

Gastrointestinal Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06596252 | ACTIVE_NOT_RECRUITING | PHASE3

308 participants

Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-05-21
Completion:: 2026-12-31

Conditions

Eosinophilic Esophagitis

Interventions

DRUG

No Results Yet

NCT06585306 | COMPLETED | NA

864 participants

High-flow Nasal Oxygen Therapy in Obese Patients Undergoing Sedativegastrointestinal Endoscopy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-23
Completion:: 2026-04-20

Conditions

Hypoxia
Obesity
Gastrostomy

Interventions

BEHAVIORAL

No Results Yet

NCT06582381 | COMPLETED | NA

30 participants

Evaluation of Biomarkers for Predicting Macronutrient Intake

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-12-06
Completion:: 2026-04-28

Conditions

Glucose Metabolism
Amino Acid Metabolism

Interventions

OTHER

No Results Yet

NCT06580405 | NOT_YET_RECRUITING | NA

13 participants

A Feasibility Study to Evaluate the Safety of the KNP-1000 Apheresis System in Severe Preeclampsia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2026-10-01
Completion:: 2027-08-31

Conditions

Pre-Eclampsia, Severe

Interventions

DEVICE

No Results Yet

NCT06579794 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2026-08-28

No Results Yet

NCT06578624 | RECRUITING | PHASE1/PHASE2

70 participants

Safety and Preliminary Efficacy of SA53-OS in Patients With Locally Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-03-10
Completion:: 2026-12-31

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06577025 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-20
Completion:: 2030-09-02

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06566885 | ACTIVE_NOT_RECRUITING

125 participants

Real-world Study Assessing Efficacy of TezepeLumaB in Patients With Severe Asthma Regardless of Phenotype in Russia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-10
Completion:: 2026-09-30

Conditions

Severe Asthma

No Results Yet

NCT06566664 | ENROLLING_BY_INVITATION | NA

150 participants

Peripheral Neurostimulation for Nerve Block Placement

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-07-23
Completion:: 2027-07-30

Conditions

Pain Syndrome
Pain Management

Interventions

DEVICE

No Results Yet

NCT06559306 | RECRUITING | PHASE3

752 participants

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-25
Completion:: 2026-12-30

Conditions

Depressive Disorder, Major

Interventions

DRUG

No Results Yet

NCT06555952 | RECRUITING | NA

80 participants

MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-08
Completion:: 2027-07-22

Conditions

Hypertension
Pre Diabetes

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06552754 | RECRUITING | NA

150 participants

Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-09-26
Completion:: 2027-02-01

Conditions

Healthy Volunteers
Virtual Reality

Interventions

BEHAVIORAL

No Results Yet

NCT06550895 | ACTIVE_NOT_RECRUITING | PHASE2

11 participants

A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-16
Completion:: 2027-08-26

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06548490 | RECRUITING | PHASE2

200 participants

GLP-1R Agonist Treatment for Opioid Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-01-27
Completion:: 2027-04-30

Conditions

Opioid Use Disorder
Opioid Abuse and Addiction
Narcotic-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorder
Opioid

Interventions

DRUG

No Results Yet

NCT06544616 | ACTIVE_NOT_RECRUITING | PHASE2

55 participants

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-22
Completion:: 2026-12-22

Conditions

Alzheimer Disease

Interventions

DRUG

No Results Yet

NCT06533098 | RECRUITING | PHASE3

50 participants

A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-10
Completion:: 2027-12-15

Conditions

Thrombocytopenia, Neonatal Alloimmune

Interventions

DRUG

No Results Yet

NCT06529718 | RECRUITING | PHASE2

72 participants

Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-10-09
Completion:: 2027-08-03

Conditions

Biliary Tract Cancer

Interventions

DRUG

No Results Yet

NCT06528496 | RECRUITING | PHASE2

45 participants

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-22
Completion:: 2029-07-22

Conditions

High-risk Neuroblastoma
Neuroblastoma
Childhood Neuroblastoma

Interventions

BIOLOGICAL
DRUG
RADIATION

No Results Yet

NCT06524544 | RECRUITING | PHASE3

320 participants

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-12-02
Completion:: 2030-12-31

Conditions

Locally Advanced Urothelial Carcinoma
Metastatic Urothelial Carcinoma
Unresectable Urothelial Carcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT06510556 | RECRUITING | NA

250 participants

Feasibility Study of the FARAFLEX Mapping and PFA System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-17
Completion:: 2027-02-15

Conditions

Atrial Fibrillation
Persistent Atrial Fibrillation
Paroxysmal AF

Interventions

DEVICE

No Results Yet