Clinical Trials Updated in 2026

NCT06559306 | RECRUITING | PHASE3

752 participants

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-25
Completion:: 2026-12-30

Conditions

Depressive Disorder, Major

Interventions

DRUG

No Results Yet

NCT06555952 | RECRUITING | NA

80 participants

MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-08
Completion:: 2027-07-22

Conditions

Hypertension
Pre Diabetes

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT06552754 | RECRUITING | NA

150 participants

Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-09-26
Completion:: 2027-02-01

Conditions

Healthy Volunteers
Virtual Reality

Interventions

BEHAVIORAL

No Results Yet

NCT06550895 | ACTIVE_NOT_RECRUITING | PHASE2

11 participants

A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-16
Completion:: 2027-08-26

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06548490 | RECRUITING | PHASE2

200 participants

GLP-1R Agonist Treatment for Opioid Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-01-27
Completion:: 2027-04-30

Conditions

Opioid Use Disorder
Opioid Abuse and Addiction
Narcotic-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorder
Opioid

Interventions

DRUG

No Results Yet

NCT06544616 | ACTIVE_NOT_RECRUITING | PHASE2

55 participants

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-22
Completion:: 2026-12-22

Conditions

Alzheimer Disease

Interventions

DRUG

No Results Yet

NCT06533098 | RECRUITING | PHASE3

50 participants

A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-10
Completion:: 2027-12-15

Conditions

Thrombocytopenia, Neonatal Alloimmune

Interventions

DRUG

No Results Yet

NCT06529718 | RECRUITING | PHASE2

72 participants

Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-10-09
Completion:: 2027-08-03

Conditions

Biliary Tract Cancer

Interventions

DRUG

No Results Yet

NCT06528496 | RECRUITING | PHASE2

45 participants

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-22
Completion:: 2029-07-22

Conditions

High-risk Neuroblastoma
Neuroblastoma
Childhood Neuroblastoma

Interventions

BIOLOGICAL
DRUG
RADIATION

No Results Yet

NCT06524544 | RECRUITING | PHASE3

320 participants

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-12-02
Completion:: 2030-12-31

Conditions

Locally Advanced Urothelial Carcinoma
Metastatic Urothelial Carcinoma
Unresectable Urothelial Carcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT06510556 | RECRUITING | NA

250 participants

Feasibility Study of the FARAFLEX Mapping and PFA System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-17
Completion:: 2027-02-15

Conditions

Atrial Fibrillation
Persistent Atrial Fibrillation
Paroxysmal AF

Interventions

DEVICE

No Results Yet

NCT06510205 | RECRUITING

6111 participants

The Study is an Observational Post-market Follow-up Program to Evaluate Long Term (5 Years) Safety of Mentor Breast Implants in Chinese Population

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-14
Completion:: 2034-06-30

Conditions

Breast Augmentation
Mammaplasty

Interventions

DEVICE

No Results Yet

NCT06507436 | COMPLETED | PHASE3

127 participants

The Phase III Clinical Study of Herombopag for the Treatment of Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-31
Completion:: 2026-08-14

Conditions

Thrombocytopenia in Chronic Liver Disease Patients Undergoing Elective Invasive Surgery

Interventions

DRUG

No Results Yet

NCT06500884 | RECRUITING | PHASE2

210 participants

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-26
Completion:: 2030-05-30

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06487000 | NOT_YET_RECRUITING | PHASE2

150 participants

Determine the Dose-dependent Efficacy and Safety of EC-18 in Patients With Moderate to Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2027-05-31
Completion:: 2027-10-31

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06479824 | SUSPENDED | NA

60 participants

NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-08-19
Completion:: 2026-10-01

Conditions

Tricuspid Valve Insufficiency

Interventions

DEVICE

No Results Yet

NCT06475937 | ACTIVE_NOT_RECRUITING | PHASE1

128 participants

A Study of DM001 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-10-24
Completion:: 2027-01-31

Conditions

Breast Neoplasms
Carcinoma, Non-Small-Cell Lung
Solid Carcinoma

Interventions

DRUG

No Results Yet

NCT06473701 | ACTIVE_NOT_RECRUITING | PHASE3

30 participants

Reducing Breathlessness With Dronabinol in COPD Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-02-26
Completion:: 2026-09-30

Conditions

COPD
Breathlessness
Cannabis

Interventions

DRUG

No Results Yet

NCT06472310 | RECRUITING

5000 participants

Clinical and demOgRaphic Features of Patients With Uncontrolled Severe Asthma in Russia (CORSAR)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-06
Completion:: 2027-06-30

Conditions

Severe Asthma

No Results Yet

NCT06470438 | ACTIVE_NOT_RECRUITING | PHASE1

58 participants

A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-05-28
Completion:: 2027-10-29

Conditions

Lymphoma, Non-Hodgkin
Refractory B-Cell NHL
Relapsed B-cell NHL

Interventions

DRUG

No Results Yet

NCT06463158 | RECRUITING | NA

100 participants

The Impact of the Family Room App on Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-01
Completion:: 2026-10-31

Conditions

Well-Being, Psychological
Engagement
Satisfaction, Consumer

Interventions

DEVICE

No Results Yet

NCT06462794 | RECRUITING | PHASE1

121 participants

First In Human Study of CX-801 in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-28
Completion:: 2028-02-28

Conditions

Solid Tumor, Adult

Interventions

DRUG

No Results Yet

NCT06462547 | ACTIVE_NOT_RECRUITING | PHASE2

22 participants

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-19
Completion:: 2026-10-31

Conditions

Gene Mutations
Pseudoxanthoma Elasticum
Arterial Calcification
Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency
Autosomal Recessive Hypophosphatemic Rickets Type 2

Interventions

DRUG

No Results Yet

NCT06460961 | COMPLETED | PHASE1

40 participants

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-14
Completion:: 2026-07-29

Conditions

Neoplasm Metastasis

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06459180 | ACTIVE_NOT_RECRUITING | PHASE3

686 participants

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-24
Completion:: 2028-06-15

Conditions

Cervical Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06455930 | COMPLETED | NA

10 participants

Stand-on Ride-on Power Mobility Devices for Children With Cerebral Palsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-01
Completion:: 2025-12-31

Conditions

Cerebral Palsy

Interventions

DEVICE

Results Available

NCT06449651 | RECRUITING | PHASE3

39 participants

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-11-11
Completion:: 2029-12-05

Conditions

Thrombocytopenia, Neonatal Alloimmune

Interventions

DRUG

No Results Yet

NCT06431815 | ACTIVE_NOT_RECRUITING

228 participants

ADVENT Post Approval Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-25
Completion:: 2028-10-31

Conditions

Paroxysmal Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT06428396 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-11-27
Completion:: 2027-05-05

Conditions

Metastatic Breast Cancer

Interventions

DRUG

No Results Yet

NCT06425991 | ACTIVE_NOT_RECRUITING | PHASE1

108 participants

A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-07
Completion:: 2025-06-03

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06423950 | RECRUITING

35 participants

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-05-01
Completion:: 2027-04-30

Conditions

Pediatric Cancer

Interventions

OTHER

No Results Yet

NCT06423430 | RECRUITING | NA

100 participants

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-09-11
Completion:: 2027-04-30

Conditions

Treatment Resistant Depression

Interventions

DEVICE

No Results Yet

NCT06422078 | RECRUITING

300 participants

A Non-interventional, Prospective Study With Benralizumab

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-07-25
Completion:: 2027-12-31

Conditions

Asthma, Bronchial

No Results Yet

NCT06420245 | ACTIVE_NOT_RECRUITING | NA

240 participants

Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2025-12-30
Completion:: 2026-11-30

Conditions

Diabetic Foot Ulcer

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT06408935 | ACTIVE_NOT_RECRUITING | PHASE3

120 participants

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-17
Completion:: 2027-06-08

Conditions

Crohn's Disease

Interventions

DRUG

No Results Yet

NCT06395103 | RECRUITING | PHASE1/PHASE2

90 participants

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-16
Completion:: 2029-03-31

Conditions

B-cell Acute Lymphoblastic Leukemia
Diffuse Large B-cell Lymphoma
Burkitt Lymphoma
Neuroblastoma
Ewing Sarcoma

Interventions

BIOLOGICAL

No Results Yet

NCT06393374 | RECRUITING | PHASE3

1530 participants

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-06-24
Completion:: 2030-12-16

Conditions

Triple-Negative Breast Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06385080 | RECRUITING | PHASE1/PHASE2

287 participants

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-04-22
Completion:: 2032-12-27

Conditions

Squamous Cell Carcinoma of Head and Neck

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06375044 | RECRUITING | PHASE1

130 participants

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-05-24
Completion:: 2027-09-30

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06373978 | RECRUITING | PHASE4

92 participants

NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2024-08-12
Completion:: 2027-06-30

Conditions

Elbow Pain
Chronic Pain

Interventions

DRUG
OTHER

No Results Yet