Clinical Trials Updated in 2026

NCT05359822 | NOT_YET_RECRUITING | NA

7000 participants

Investigating the Impact of a Patient-directed Coronary Artery Calcium Score Report

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2027-01-01
Completion:: 2027-05-31

Conditions

Cardiac Computed Tomography for Calicum Scoring

Interventions

OTHER

No Results Yet

NCT05347095 | ACTIVE_NOT_RECRUITING | PHASE3

288 participants

A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-09-27
Completion:: 2027-03-25

Conditions

Fistulizing Crohns Disease
Perianal Crohns Disease

Interventions

DRUG

No Results Yet

NCT05344833 | RECRUITING | PHASE2

50 participants

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-01-05
Completion:: 2030-12-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05338775 | ACTIVE_NOT_RECRUITING | PHASE1

74 participants

A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-05-25
Completion:: 2025-05-22

Conditions

Relapsed/ Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05328765 | COMPLETED

369 participants

A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-06-09
Completion:: 2025-02-07

Conditions

Anal Squamous Cell Carcinoma
HIV Infections

No Results Yet

NCT05327114 | RECRUITING | PHASE2/PHASE3

201 participants

Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-09-23
Completion:: 2027-05-14

Conditions

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Interventions

DRUG

No Results Yet

NCT05316155 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

235 participants

Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-04-11
Completion:: 2028-03-30

Conditions

Non-Muscle Invasive Bladder Neoplasms

Interventions

DRUG

No Results Yet

NCT05303519 | RECRUITING | PHASE3

365 participants

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-06-05
Completion:: 2028-12-01

Conditions

Glioma
Astrocytoma, Grade IV
IDH1-mutant Glioma
Astrocytoma, IDH-Mutant, Grade 3
Astrocytoma, IDH-Mutant, Grade 4
Astrocytoma, IDH-Mutant, Grade 2
Oligodendroglioma
Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted

Interventions

DRUG

No Results Yet

NCT05299125 | COMPLETED | PHASE2

54 participants

Amivantamab, Lazertinib, and Pemetrexed for First-line Treatment of Recurrent/Metastatic Non-small Cell Lung Cancers With Epidermal Growth Factor Receptor Mutations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-05-24
Completion:: 2024-08-19

Conditions

Metastatic Non-small Cell Lung Cancers

Interventions

DRUG

No Results Yet

NCT05298423 | COMPLETED | PHASE3

610 participants

Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-05-03
Completion:: 2026-06-15

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

BIOLOGICAL
DRUG
RADIATION

No Results Yet

NCT05286333 | COMPLETED

51 participants

Identification of Risk Factors for Recurrence of Low Back Pain and Occupational Repercussions

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-05-30
Completion:: 2026-04-01

Conditions

Low Back Pain

No Results Yet

NCT05257681 | RECRUITING | NA

20 participants

Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-05-24
Completion:: 2026-12-24

Conditions

Emphysema or COPD

Interventions

PROCEDURE

No Results Yet

NCT05250973 | ACTIVE_NOT_RECRUITING | PHASE2

151 participants

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-03-01
Completion:: 2026-02-04

Conditions

Amyloidosis

Interventions

DRUG

No Results Yet

NCT05242484 | ACTIVE_NOT_RECRUITING | PHASE2

577 participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-09-19
Completion:: 2025-05-15

Conditions

Colitis, Ulcerative

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05242471 | ACTIVE_NOT_RECRUITING | PHASE2

703 participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-07-22
Completion:: 2025-05-23

Conditions

Crohn's Disease

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05220202 | COMPLETED | NA

214 participants

MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2023-09-20
Completion:: 2026-07-09

Conditions

Chronic Back Pain
Depression
Aging
Musculoskeletal Pain

Interventions

BEHAVIORAL

No Results Yet

NCT05211895 | ACTIVE_NOT_RECRUITING | PHASE3

791 participants

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-02-18
Completion:: 2026-08-10

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG
OTHER

No Results Yet

NCT05201781 | RECRUITING | PHASE4

295 participants

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-03-09
Completion:: 2037-07-29

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05196035 | ACTIVE_NOT_RECRUITING | PHASE3

219 participants

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-03-28
Completion:: 2027-04-10

Conditions

Chronic Kidney Disease
Proteinuria

Interventions

DRUG

No Results Yet

NCT05185180 | COMPLETED

11 participants

Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-10-11
Completion:: 2023-03-07

Conditions

Chronic Pelvic Pain

Results Available

NCT05179876 | RECRUITING | PHASE3

280 participants

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-05-04
Completion:: 2027-01-31

Conditions

Hypertension, Pulmonary

Interventions

DRUG

No Results Yet

NCT05171816 | ACTIVE_NOT_RECRUITING | PHASE3

110 participants

Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-06-24
Completion:: 2024-01-22

Conditions

Metastatic Castration-resistant Prostate Cancer

Interventions

DRUG

Results Available

NCT05168631 | COMPLETED

88 participants

Multicenter Retrospective Database on Prognostic and Predictive Factors in Patients With Neuroendocrine Tumors

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2020-05-16
Completion:: 2022-06-28

Conditions

Neuroendocrine Tumors
Carcinoma;Endocrine

No Results Yet

NCT05168280 | COMPLETED | NA

420 participants

Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium in Elderly Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-07-18
Completion:: 2026-05-30

Conditions

Dexmedetomidine
Postoperative Delirium

Interventions

DRUG

No Results Yet

NCT05160584 | RECRUITING

300 participants

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-11-18
Completion:: 2028-04-30

Conditions

Relapsed/Refractory Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT05126758 | ACTIVE_NOT_RECRUITING | PHASE3

106 participants

A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-06-22
Completion:: 2025-06-18

Conditions

Muscular Dystrophies
Muscular Dystrophy, Duchenne
Muscular Disorders, Atrophic
Muscular Diseases
Neuromuscular Diseases
Genetic Diseases, X-Linked
Genetic Diseases, Inborn
Nervous System Diseases

Interventions

BIOLOGICAL

No Results Yet

NCT05119231 | ACTIVE_NOT_RECRUITING | NA

262 participants

Pulmonary Vein Isolation vs SHAM-pulmonary Vein Isolation for Symptomatic Relief in Patients With AF

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-11-12
Completion:: 2026-06-01

Conditions

Atrial Fibrillation

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05104736 | RECRUITING | PHASE2

53 participants

PT-112 in Subjects With Thymoma and Thymic Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-04-06
Completion:: 2027-12-31

Conditions

Thymic Epithelial Tumor
Recurrent Thymoma
Thymic Cancer

Interventions

DRUG

No Results Yet

NCT05092269 | ACTIVE_NOT_RECRUITING | PHASE3

159 participants

A Long-term Extension Study of Ustekinumab in Pediatric Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-10-18
Completion:: 2027-09-29

Conditions

Crohn Disease
Colitis, Ulcerative
Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT05083169 | ACTIVE_NOT_RECRUITING | PHASE3

587 participants

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-10-14
Completion:: 2025-09-15

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05058638 | RECRUITING | PHASE2

25 participants

Effectiveness of Aquamin® in Mitigating Halitosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-08-15
Completion:: 2027-12-31

Conditions

Healthy
Halitosis

Interventions

DRUG

No Results Yet

NCT05050097 | ACTIVE_NOT_RECRUITING | PHASE1

166 participants

A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-09-22
Completion:: 2025-03-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05049798 | ACTIVE_NOT_RECRUITING

1314 participants

A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-08-25
Completion:: 2027-08-01

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT04989803 | RECRUITING | PHASE1/PHASE2

247 participants

Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-10-27
Completion:: 2030-02-28

Conditions

Relapsed and/or Refractory B-cell Lymphoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04971226 | ACTIVE_NOT_RECRUITING | PHASE3

405 participants

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-10-06
Completion:: 2023-11-28

Conditions

Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive

Interventions

DRUG

Results Available

NCT04959253 | COMPLETED | PHASE2

60 participants

Psilocybin in Depression Resistant to Standard Treatments

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-06-21
Completion:: 2024-12-18

Conditions

Treatment Resistant Depression

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT04957550 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

To Evaluate the Efficacy and Safety of SHR0302 Tablet in Subjects of Active Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-08-30
Completion:: 2026-12-13

Conditions

Psoriatic Arthritis

Interventions

DRUG

No Results Yet

NCT04936685 | ACTIVE_NOT_RECRUITING | PHASE3

209 participants

Study on an Investigational Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Administered as a 5- and/or 10-year Booster Doses in Children and Adolescents Vaccinated 5 or 10 Years Earlier as Toddlers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2022-08-23
Completion:: 2023-03-09

Conditions

Meningococcal Immunisation
Healthy Volunteers

Interventions

BIOLOGICAL

Results Available

NCT04929210 | ACTIVE_NOT_RECRUITING | PHASE4

411 participants

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-08-30
Completion:: 2027-04-01

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT04923893 | ACTIVE_NOT_RECRUITING | PHASE3

743 participants

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2021-08-19
Completion:: 2029-02-14

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet