Clinical Trials

NCT05303519 | RECRUITING | PHASE3

365 participants

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-06-05

Completion:

2028-12-01

Conditions

• Glioma
• Astrocytoma, Grade IV
• IDH1-mutant Glioma
• Astrocytoma, IDH-Mutant, Grade 3
• Astrocytoma, IDH-Mutant, Grade 4
• Astrocytoma, IDH-Mutant, Grade 2
• Oligodendroglioma
• Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted

Interventions

• DRUG

No Results Yet

NCT05299125 | COMPLETED | PHASE2

54 participants

Amivantamab, Lazertinib, and Pemetrexed for First-line Treatment of Recurrent/Metastatic Non-small Cell Lung Cancers With Epidermal Growth Factor Receptor Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-05-24

Completion:

2024-08-19

Conditions

• Metastatic Non-small Cell Lung Cancers

Interventions

• DRUG

No Results Yet

NCT05298423 | COMPLETED | PHASE3

610 participants

Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-03

Completion:

2026-06-15

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• BIOLOGICAL
• DRUG
• RADIATION

No Results Yet

NCT05286333 | COMPLETED

51 participants

Identification of Risk Factors for Recurrence of Low Back Pain and Occupational Repercussions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-30

Completion:

2026-04-01

Conditions

• Low Back Pain

No Results Yet

NCT05257681 | RECRUITING | NA

20 participants

Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-24

Completion:

2026-12-24

Conditions

• Emphysema or COPD

Interventions

• PROCEDURE

No Results Yet

NCT05250973 | ACTIVE_NOT_RECRUITING | PHASE2

151 participants

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-03-01

Completion:

2026-02-04

Conditions

• Amyloidosis

Interventions

• DRUG

No Results Yet

NCT05242484 | ACTIVE_NOT_RECRUITING | PHASE2

577 participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-19

Completion:

2025-05-15

Conditions

• Colitis, Ulcerative

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05242471 | ACTIVE_NOT_RECRUITING | PHASE2

703 participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-07-22

Completion:

2025-05-23

Conditions

• Crohn's Disease

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05220202 | COMPLETED | NA

214 participants

MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-09-20

Completion:

2026-07-09

Conditions

• Chronic Back Pain
• Depression
• Aging
• Musculoskeletal Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT05211895 | ACTIVE_NOT_RECRUITING | PHASE3

791 participants

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-02-18

Completion:

2026-08-10

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT05201781 | RECRUITING | PHASE4

295 participants

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-03-09

Completion:

2037-07-29

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05196035 | ACTIVE_NOT_RECRUITING | PHASE3

219 participants

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-03-28

Completion:

2027-04-10

Conditions

• Chronic Kidney Disease
• Proteinuria

Interventions

• DRUG

No Results Yet

NCT05185180 | COMPLETED

11 participants

Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-10-11

Completion:

2023-03-07

Conditions

• Chronic Pelvic Pain

Results Available

NCT05179876 | RECRUITING | PHASE3

280 participants

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-04

Completion:

2027-01-31

Conditions

• Hypertension, Pulmonary

Interventions

• DRUG

No Results Yet

NCT05171816 | ACTIVE_NOT_RECRUITING | PHASE3

110 participants

Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-06-24

Completion:

2024-01-22

Conditions

• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

Results Available

NCT05168631 | COMPLETED

88 participants

Multicenter Retrospective Database on Prognostic and Predictive Factors in Patients With Neuroendocrine Tumors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2020-05-16

Completion:

2022-06-28

Conditions

• Neuroendocrine Tumors
• Carcinoma;Endocrine

No Results Yet

NCT05168280 | COMPLETED | NA

420 participants

Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium in Elderly Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-07-18

Completion:

2026-05-30

Conditions

• Dexmedetomidine
• Postoperative Delirium

Interventions

• DRUG

No Results Yet

NCT05160584 | RECRUITING

300 participants

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-11-18

Completion:

2028-04-30

Conditions

• Relapsed/Refractory Multiple Myeloma

Interventions

• OTHER

No Results Yet

NCT05126758 | ACTIVE_NOT_RECRUITING | PHASE3

106 participants

A Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-06-22

Completion:

2025-06-18

Conditions

• Muscular Dystrophies
• Muscular Dystrophy, Duchenne
• Muscular Disorders, Atrophic
• Muscular Diseases
• Neuromuscular Diseases
• Genetic Diseases, X-Linked
• Genetic Diseases, Inborn
• Nervous System Diseases

Interventions

• BIOLOGICAL

No Results Yet

NCT05119231 | ACTIVE_NOT_RECRUITING | NA

262 participants

Pulmonary Vein Isolation vs SHAM-pulmonary Vein Isolation for Symptomatic Relief in Patients With AF

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-11-12

Completion:

2026-06-01

Conditions

• Atrial Fibrillation

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05108298 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

500 participants

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-11-10

Completion:

2027-05-01

Conditions

• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT05104736 | RECRUITING | PHASE2

53 participants

PT-112 in Subjects With Thymoma and Thymic Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-04-06

Completion:

2027-12-31

Conditions

• Thymic Epithelial Tumor
• Recurrent Thymoma
• Thymic Cancer

Interventions

• DRUG

No Results Yet

NCT05092269 | ACTIVE_NOT_RECRUITING | PHASE3

159 participants

A Long-term Extension Study of Ustekinumab in Pediatric Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-10-18

Completion:

2027-09-29

Conditions

• Crohn Disease
• Colitis, Ulcerative
• Arthritis, Psoriatic

Interventions

• DRUG

No Results Yet

NCT05083169 | ACTIVE_NOT_RECRUITING | PHASE3

587 participants

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-10-14

Completion:

2025-09-15

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05058638 | RECRUITING | PHASE2

25 participants

Effectiveness of Aquamin® in Mitigating Halitosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-15

Completion:

2027-12-31

Conditions

• Healthy
• Halitosis

Interventions

• DRUG

No Results Yet

NCT05050097 | ACTIVE_NOT_RECRUITING | PHASE1

166 participants

A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-09-22

Completion:

2025-03-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05049798 | ACTIVE_NOT_RECRUITING

1314 participants

A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-08-25

Completion:

2027-08-01

Conditions

• Arthritis, Psoriatic

Interventions

• DRUG

No Results Yet

NCT04989803 | RECRUITING | PHASE1/PHASE2

247 participants

Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-10-27

Completion:

2030-02-28

Conditions

• Relapsed and/or Refractory B-cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04971226 | ACTIVE_NOT_RECRUITING | PHASE3

405 participants

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-10-06

Completion:

2023-11-28

Conditions

• Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive

Interventions

• DRUG

Results Available

NCT04959253 | COMPLETED | PHASE2

60 participants

Psilocybin in Depression Resistant to Standard Treatments

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-06-21

Completion:

2024-12-18

Conditions

• Treatment Resistant Depression

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04957550 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

To Evaluate the Efficacy and Safety of SHR0302 Tablet in Subjects of Active Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-08-30

Completion:

2026-12-13

Conditions

• Psoriatic Arthritis

Interventions

• DRUG

No Results Yet

NCT04936685 | ACTIVE_NOT_RECRUITING | PHASE3

209 participants

Study on an Investigational Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Administered as a 5- and/or 10-year Booster Doses in Children and Adolescents Vaccinated 5 or 10 Years Earlier as Toddlers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-23

Completion:

2023-03-09

Conditions

• Meningococcal Immunisation
• Healthy Volunteers

Interventions

• BIOLOGICAL

Results Available

NCT04929210 | ACTIVE_NOT_RECRUITING | PHASE4

411 participants

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-08-30

Completion:

2027-04-01

Conditions

• Arthritis, Psoriatic

Interventions

• DRUG

No Results Yet

NCT04923893 | ACTIVE_NOT_RECRUITING | PHASE3

743 participants

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-08-19

Completion:

2029-02-14

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT04896060 | COMPLETED

5056 participants

The Impact of the COVID-19 Pandemic on Eating Behavior and Weight Change

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-01

Completion:

2025-02-13

Conditions

• COVID-19
• Obesity

No Results Yet

NCT04892173 | RECRUITING | PHASE3

500 participants

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-12-10

Completion:

2028-06-30

Conditions

• Carcinoma, Squamous Cell

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04882098 | ACTIVE_NOT_RECRUITING | PHASE3

1054 participants

A Study of Guselkumab in Participants With Active Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-06-17

Completion:

2024-12-30

Conditions

• Arthritis, Psoriatic

Interventions

• DRUG

Results Available

NCT04863573 | ACTIVE_NOT_RECRUITING

1000 participants

COVID-19 Antibody Responses In Cystic Fibrosis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-11-19

Completion:

2027-08-31

Conditions

• Covid19
• Cystic Fibrosis

No Results Yet

NCT04816591 | COMPLETED | NA

376 participants

Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL® n-BCA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-05-27

Completion:

2024-08-15

Conditions

• Chronic Subdural Hematoma

Interventions

• DEVICE
• OTHER

Results Available

NCT04811560 | RECRUITING | PHASE1/PHASE2

420 participants

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-05-19

Completion:

2027-02-26

Conditions

• Acute Leukemia

Interventions

• DRUG

No Results Yet