Clinical Trials

NCT05560932 | COMPLETED | NA

50 participants

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 1

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-03-06

Completion:

2024-01-04

Conditions

• HIV
• Alcohol Use

Interventions

• BEHAVIORAL

Results Available

NCT05552222 | RECRUITING | PHASE3

1590 participants

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-10-25

Completion:

2031-04-30

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05545306 | RECRUITING | NA

120 participants

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-06-06

Completion:

2027-02-02

Conditions

• Obesity
• Normal Physiology
• Healthy Volunteers

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05543512 | COMPLETED | NA

68 participants

The Immune Directed Individualized Elimination Therapy (iDIET) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-10-24

Completion:

2025-12-18

Conditions

• Eosinophilic Esophagitis
• EoE

Interventions

• DEVICE
• OTHER

Results Available

NCT05531565 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

450 participants

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-13

Completion:

2026-10-20

Conditions

• Subacute Cutaneous Lupus Erythematosus
• Chronic Cutaneous Lupus Erythematosus

Interventions

• DRUG

No Results Yet

NCT05531396 | COMPLETED | NA

57 participants

Agility Training on Physical Performance, Cognitive Function and Brain Activities in Elderly

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-28

Completion:

2025-06-04

Conditions

• Elderly
• Healthy

Interventions

• OTHER

No Results Yet

NCT05529654 | COMPLETED | NA

100 participants

IMpella-Protected cArdiaC Surgery Trial (IMPACT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-09-21

Completion:

2025-11-04

Conditions

• Left Ventricular Dysfunction

Interventions

• DEVICE

No Results Yet

NCT05528510 | ACTIVE_NOT_RECRUITING | PHASE3

418 participants

A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-13

Completion:

2024-04-02

Conditions

• Colitis, Ulcerative

Interventions

• DRUG
• OTHER

Results Available

NCT05512390 | ACTIVE_NOT_RECRUITING | PHASE1

39 participants

A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-04-26

Completion:

2027-02-28

Conditions

• Diffuse Large B-Cell Lymphoma
• Chronic Lymphocytic Leukemia
• Follicular Lymphoma

Interventions

• DRUG

No Results Yet

NCT05498428 | RECRUITING | PHASE2

520 participants

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-11-11

Completion:

2027-08-17

Conditions

• Carcinoma, Non-small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT05493904 | ACTIVE_NOT_RECRUITING | NA

320 participants

PREcise Percutaneous Coronary Intervention for Stent OptimizatION in Treatment of COMPLEX Lesion (PRECISION-COMPLEX)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-11-01

Completion:

2024-12-05

Conditions

• Coronary Artery Disease
• Angina Pectoris

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT05488314 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

57 participants

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-12-13

Completion:

2027-04-28

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT05480995 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-01-17

Completion:

2026-08-31

Conditions

• Endometriosis

Interventions

• DRUG

No Results Yet

NCT05455320 | ACTIVE_NOT_RECRUITING | PHASE3

864 participants

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-10-13

Completion:

2027-07-30

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05454787 | RECRUITING

300 participants

Ondexxya for Intravenous Injection 200mg Drug Use Result Investigation (All Case Investigation)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2022-06-02

Completion:

2026-10-31

Conditions

• Life Threatening Bleeding
• Factor Xa Inhibitor

No Results Yet

NCT05453903 | ACTIVE_NOT_RECRUITING | PHASE1

196 participants

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-10-04

Completion:

2026-10-30

Conditions

• Leukemia, Myeloid, Acute

Interventions

• DRUG

No Results Yet

NCT05445908 | COMPLETED | PHASE2

184 participants

SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-17

Completion:

2026-07-31

Conditions

• Triple-negative Breast Cancer and HR+/HER2- BC

Interventions

• DRUG

No Results Yet

NCT05438043 | ACTIVE_NOT_RECRUITING | PHASE3

213 participants

A Study of Daratumumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-12-15

Completion:

2029-01-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05424822 | ACTIVE_NOT_RECRUITING | PHASE1

167 participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-18

Completion:

2025-10-31

Conditions

• Lymphoma, Non-Hodgkin
• Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

• DRUG

No Results Yet

NCT05423756 | COMPLETED | NA

118562 participants

INSPIRE Trial for Skin and Soft Tissue Infections

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-01-01

Completion:

2024-05-09

Conditions

• Skin and Soft Tissue (SST) Infection

Interventions

• OTHER

Results Available

NCT05421858 | RECRUITING | PHASE3

450 participants

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-11

Completion:

2028-01-30

Conditions

• Candidemia
• Candidiasis, Invasive

Interventions

• DRUG

No Results Yet

NCT05421663 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

166 participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-12

Completion:

2041-07-30

Conditions

• Lymphoma, Non-Hodgkin
• Lymphoma, B-Cell
• Lymphoma, Large B-Cell, Diffuse

Interventions

• BIOLOGICAL

No Results Yet

NCT05416255 | COMPLETED | NA

80 participants

Measuring Synovial Fluid Components

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-04-19

Completion:

2026-04-20

Conditions

• Knee Osteoarthritis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05403476 | TERMINATED | PHASE2

4 participants

A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-16

Completion:

2024-10-05

Conditions

• Male Idiopathic Infertility

Interventions

• DRUG

Results Available

NCT05384158 | RECRUITING | NA

252 participants

Valuation in Depressed Mood, Anhedonia, and Anxiety

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-08-01

Completion:

2027-07-31

Conditions

• Neurobehavioral Components of Reward and Loss Valuation

Interventions

• BEHAVIORAL

No Results Yet

NCT05379595 | RECRUITING | PHASE1/PHASE2

225 participants

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-07-29

Completion:

2027-04-27

Conditions

• Advanced or Metastatic Colorectal Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT05359822 | NOT_YET_RECRUITING | NA

7000 participants

Investigating the Impact of a Patient-directed Coronary Artery Calcium Score Report

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2027-01-01

Completion:

2027-05-31

Conditions

• Cardiac Computed Tomography for Calicum Scoring

Interventions

• OTHER

No Results Yet

NCT05352919 | ENROLLING_BY_INVITATION | PHASE3

864 participants

An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-06-10

Completion:

2030-03-29

Conditions

• Systemic Lupus Erythematosus (SLE)

Interventions

• DRUG

No Results Yet

NCT05347095 | ACTIVE_NOT_RECRUITING | PHASE3

288 participants

A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-27

Completion:

2027-03-25

Conditions

• Fistulizing Crohns Disease
• Perianal Crohns Disease

Interventions

• DRUG

No Results Yet

NCT05344833 | RECRUITING | PHASE2

50 participants

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-01-05

Completion:

2030-12-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05338775 | ACTIVE_NOT_RECRUITING | PHASE1

74 participants

A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-25

Completion:

2025-05-22

Conditions

• Relapsed/ Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05328765 | COMPLETED

369 participants

A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2023-06-09

Completion:

2025-02-07

Conditions

• Anal Squamous Cell Carcinoma
• HIV Infections

No Results Yet

NCT05327114 | RECRUITING | PHASE2/PHASE3

201 participants

Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-23

Completion:

2027-05-14

Conditions

• Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Interventions

• DRUG

No Results Yet

NCT05316155 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

235 participants

Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-04-11

Completion:

2028-03-30

Conditions

• Non-Muscle Invasive Bladder Neoplasms

Interventions

• DRUG

No Results Yet

NCT05303519 | RECRUITING | PHASE3

365 participants

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-06-05

Completion:

2028-12-01

Conditions

• Glioma
• Astrocytoma, Grade IV
• IDH1-mutant Glioma
• Astrocytoma, IDH-Mutant, Grade 3
• Astrocytoma, IDH-Mutant, Grade 4
• Astrocytoma, IDH-Mutant, Grade 2
• Oligodendroglioma
• Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted

Interventions

• DRUG

No Results Yet

NCT05299125 | COMPLETED | PHASE2

54 participants

Amivantamab, Lazertinib, and Pemetrexed for First-line Treatment of Recurrent/Metastatic Non-small Cell Lung Cancers With Epidermal Growth Factor Receptor Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-05-24

Completion:

2024-08-19

Conditions

• Metastatic Non-small Cell Lung Cancers

Interventions

• DRUG

No Results Yet

NCT05298423 | COMPLETED | PHASE3

610 participants

Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-03

Completion:

2026-06-15

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• BIOLOGICAL
• DRUG
• RADIATION

No Results Yet

NCT05286333 | COMPLETED

51 participants

Identification of Risk Factors for Recurrence of Low Back Pain and Occupational Repercussions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-30

Completion:

2026-04-01

Conditions

• Low Back Pain

No Results Yet

NCT05257681 | RECRUITING | NA

20 participants

Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-24

Completion:

2026-12-24

Conditions

• Emphysema or COPD

Interventions

• PROCEDURE

No Results Yet

NCT05250973 | ACTIVE_NOT_RECRUITING | PHASE2

151 participants

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-03-01

Completion:

2026-02-04

Conditions

• Amyloidosis

Interventions

• DRUG

No Results Yet