Clinical Trials

NCT05453903 | ACTIVE_NOT_RECRUITING | PHASE1

196 participants

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-10-04

Completion:

2026-10-30

Conditions

• Leukemia, Myeloid, Acute

Interventions

• DRUG

No Results Yet

NCT05445908 | COMPLETED | PHASE2

184 participants

SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-17

Completion:

2026-07-31

Conditions

• Triple-negative Breast Cancer and HR+/HER2- BC

Interventions

• DRUG

No Results Yet

NCT05438043 | ACTIVE_NOT_RECRUITING | PHASE3

213 participants

A Study of Daratumumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-12-15

Completion:

2029-01-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05424822 | ACTIVE_NOT_RECRUITING | PHASE1

167 participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-18

Completion:

2025-10-31

Conditions

• Lymphoma, Non-Hodgkin
• Leukemia, Lymphocytic, Chronic, B-Cell

Interventions

• DRUG

No Results Yet

NCT05423756 | COMPLETED | NA

118562 participants

INSPIRE Trial for Skin and Soft Tissue Infections

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-01-01

Completion:

2024-05-09

Conditions

• Skin and Soft Tissue (SST) Infection

Interventions

• OTHER

Results Available

NCT05421858 | RECRUITING | PHASE3

450 participants

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2024-12-11

Completion:

2028-01-30

Conditions

• Candidemia
• Candidiasis, Invasive

Interventions

• DRUG

No Results Yet

NCT05421663 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

166 participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-12

Completion:

2041-07-30

Conditions

• Lymphoma, Non-Hodgkin
• Lymphoma, B-Cell
• Lymphoma, Large B-Cell, Diffuse

Interventions

• BIOLOGICAL

No Results Yet

NCT05416255 | COMPLETED | NA

80 participants

Measuring Synovial Fluid Components

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-04-19

Completion:

2026-04-20

Conditions

• Knee Osteoarthritis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05403476 | TERMINATED | PHASE2

4 participants

A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-08-16

Completion:

2024-10-05

Conditions

• Male Idiopathic Infertility

Interventions

• DRUG

Results Available

NCT05384158 | RECRUITING | NA

252 participants

Valuation in Depressed Mood, Anhedonia, and Anxiety

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-08-01

Completion:

2027-07-31

Conditions

• Neurobehavioral Components of Reward and Loss Valuation

Interventions

• BEHAVIORAL

No Results Yet

NCT05379595 | RECRUITING | PHASE1/PHASE2

225 participants

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-07-29

Completion:

2027-04-27

Conditions

• Advanced or Metastatic Colorectal Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT05361798 | RECRUITING | PHASE2

65 participants

A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine PDS01ADC in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-06-12

Completion:

2027-08-01

Conditions

• Cancer Of Prostate

Interventions

• DRUG
• RADIATION

No Results Yet

NCT05359822 | NOT_YET_RECRUITING | NA

7000 participants

Investigating the Impact of a Patient-directed Coronary Artery Calcium Score Report

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2027-01-01

Completion:

2027-05-31

Conditions

• Cardiac Computed Tomography for Calicum Scoring

Interventions

• OTHER

No Results Yet

NCT05352919 | ENROLLING_BY_INVITATION | PHASE3

864 participants

An Extension Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-06-10

Completion:

2030-03-29

Conditions

• Systemic Lupus Erythematosus (SLE)

Interventions

• DRUG

No Results Yet

NCT05347095 | ACTIVE_NOT_RECRUITING | PHASE3

288 participants

A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-27

Completion:

2027-03-25

Conditions

• Fistulizing Crohns Disease
• Perianal Crohns Disease

Interventions

• DRUG

No Results Yet

NCT05344833 | RECRUITING | PHASE2

50 participants

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-01-05

Completion:

2030-12-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05338775 | ACTIVE_NOT_RECRUITING | PHASE1

74 participants

A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-25

Completion:

2025-05-22

Conditions

• Relapsed/ Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05328765 | COMPLETED

369 participants

A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2023-06-09

Completion:

2025-02-07

Conditions

• Anal Squamous Cell Carcinoma
• HIV Infections

No Results Yet

NCT05327114 | RECRUITING | PHASE2/PHASE3

201 participants

Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-23

Completion:

2027-05-14

Conditions

• Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Interventions

• DRUG

No Results Yet

NCT05316155 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

235 participants

Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-04-11

Completion:

2028-03-30

Conditions

• Non-Muscle Invasive Bladder Neoplasms

Interventions

• DRUG

No Results Yet

NCT05303519 | RECRUITING | PHASE3

365 participants

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-06-05

Completion:

2028-12-01

Conditions

• Glioma
• Astrocytoma, Grade IV
• IDH1-mutant Glioma
• Astrocytoma, IDH-Mutant, Grade 3
• Astrocytoma, IDH-Mutant, Grade 4
• Astrocytoma, IDH-Mutant, Grade 2
• Oligodendroglioma
• Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted

Interventions

• DRUG

No Results Yet

NCT05299125 | COMPLETED | PHASE2

54 participants

Amivantamab, Lazertinib, and Pemetrexed for First-line Treatment of Recurrent/Metastatic Non-small Cell Lung Cancers With Epidermal Growth Factor Receptor Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-05-24

Completion:

2024-08-19

Conditions

• Metastatic Non-small Cell Lung Cancers

Interventions

• DRUG

No Results Yet

NCT05298423 | COMPLETED | PHASE3

610 participants

Study of Pembrolizumab/Vibostolimab (MK-7684A) in Combination With Concurrent Chemoradiotherapy Followed by Pembrolizumab/Vibostolimab Versus Concurrent Chemoradiotherapy Followed by Durvalumab in Participants With Stage III Non-small Cell Lung Cancer (MK-7684A-006)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-03

Completion:

2026-06-15

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• BIOLOGICAL
• DRUG
• RADIATION

No Results Yet

NCT05286333 | COMPLETED

51 participants

Identification of Risk Factors for Recurrence of Low Back Pain and Occupational Repercussions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-30

Completion:

2026-04-01

Conditions

• Low Back Pain

No Results Yet

NCT05257681 | RECRUITING | NA

20 participants

Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-24

Completion:

2026-12-24

Conditions

• Emphysema or COPD

Interventions

• PROCEDURE

No Results Yet

NCT05250973 | ACTIVE_NOT_RECRUITING | PHASE2

151 participants

A Study of Daratumumab-Based Therapies in Participants With Amyloid Light Chain (AL) Amyloidosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-03-01

Completion:

2026-02-04

Conditions

• Amyloidosis

Interventions

• DRUG

No Results Yet

NCT05242484 | ACTIVE_NOT_RECRUITING | PHASE2

577 participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-09-19

Completion:

2025-05-15

Conditions

• Colitis, Ulcerative

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05242471 | ACTIVE_NOT_RECRUITING | PHASE2

703 participants

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-07-22

Completion:

2025-05-23

Conditions

• Crohn's Disease

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05220202 | COMPLETED | NA

214 participants

MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2023-09-20

Completion:

2026-07-09

Conditions

• Chronic Back Pain
• Depression
• Aging
• Musculoskeletal Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT05211895 | ACTIVE_NOT_RECRUITING | PHASE3

791 participants

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-02-18

Completion:

2026-08-10

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT05201781 | RECRUITING | PHASE4

295 participants

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-03-09

Completion:

2037-07-29

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT05196035 | ACTIVE_NOT_RECRUITING | PHASE3

219 participants

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-03-28

Completion:

2027-04-10

Conditions

• Chronic Kidney Disease
• Proteinuria

Interventions

• DRUG

No Results Yet

NCT05185180 | COMPLETED

11 participants

Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-10-11

Completion:

2023-03-07

Conditions

• Chronic Pelvic Pain

Results Available

NCT05179876 | RECRUITING | PHASE3

280 participants

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-05-04

Completion:

2027-01-31

Conditions

• Hypertension, Pulmonary

Interventions

• DRUG

No Results Yet

NCT05171816 | ACTIVE_NOT_RECRUITING | PHASE3

110 participants

Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2021-06-24

Completion:

2024-01-22

Conditions

• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

Results Available

NCT05168631 | COMPLETED

88 participants

Multicenter Retrospective Database on Prognostic and Predictive Factors in Patients With Neuroendocrine Tumors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2020-05-16

Completion:

2022-06-28

Conditions

• Neuroendocrine Tumors
• Carcinoma;Endocrine

No Results Yet

NCT05168280 | COMPLETED | NA

420 participants

Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium in Elderly Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-07-18

Completion:

2026-05-30

Conditions

• Dexmedetomidine
• Postoperative Delirium

Interventions

• DRUG

No Results Yet

NCT05160584 | RECRUITING

300 participants

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-28

Start Date:

2021-11-18

Completion:

2028-04-30

Conditions

• Relapsed/Refractory Multiple Myeloma

Interventions

• OTHER

No Results Yet

NCT05139017 | RECRUITING | PHASE2/PHASE3

290 participants

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-01-14

Completion:

2027-09-24

Conditions

• DLBCL
• Diffuse Large B-Cell Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05136196 | RECRUITING | PHASE2

150 participants

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-28

Start Date:

2022-12-06

Completion:

2027-01-01

Conditions

• Clinical Stage III Cutaneous Melanoma AJCC v8
• Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Clinical Stage IV Cutaneous Melanoma AJCC v8
• Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
• Locally Recurrent Head and Neck Squamous Cell Carcinoma
• Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma
• Locally Recurrent Laryngeal Squamous Cell Carcinoma
• Locally Recurrent Oral Cavity Squamous Cell Carcinoma
• Locally Recurrent Oropharyngeal Squamous Cell Carcinoma
• Metastatic Head and Neck Squamous Cell Carcinoma
• Metastatic Hypopharyngeal Squamous Cell Carcinoma
• Metastatic Laryngeal Squamous Cell Carcinoma
• Metastatic Melanoma
• Metastatic Oral Cavity Squamous Cell Carcinoma
• Metastatic Oropharyngeal Squamous Cell Carcinoma
• Recurrent Melanoma
• Stage III Hypopharyngeal Carcinoma AJCC v8
• Stage III Laryngeal Cancer AJCC v8
• Stage III Lip and Oral Cavity Cancer AJCC v8
• Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
• Stage IV Hypopharyngeal Carcinoma AJCC v8
• Stage IV Laryngeal Cancer AJCC v8
• Stage IV Lip and Oral Cavity Cancer AJCC v8
• Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
• Unresectable Melanoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet