Clinical Trials Updated in 2026

NCT03053141 | RECRUITING

100 participants

RHythmia mAPping and Signal acquisitiOn for Data analYsis (RHAPSODY)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-05-31
Completion:: 2027-12-31

Conditions

Cardiac Arrythmias

Interventions

DEVICE

No Results Yet

NCT02997228 | ACTIVE_NOT_RECRUITING | PHASE3

120 participants

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-01-19
Completion:: 2027-06-01

Conditions

Metastatic Colorectal Adenocarcinoma
Stage IV Colorectal Cancer AJCC v7

Interventions

DRUG
BIOLOGICAL
PROCEDURE
OTHER

No Results Yet

NCT02941263 | COMPLETED

20 participants

Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-03-08
Completion:: 2024-05-22

Conditions

Age-Related Macular Degeneration

No Results Yet

NCT02919592 | ACTIVE_NOT_RECRUITING | NA

3603 participants

Memory Gel and Shape Combined Cohort

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-09-01
Completion:: 2031-09-16

Conditions

Primary Breast Augmentation
Primary Breast Reconstruction
Revision Breast Augmentation
Revision Breast Reconstruction

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT02911103 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

5 participants

Deep Brain Stimulation Surgery for Focal Hand Dystonia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-01-17
Completion:: 2029-02-02

Conditions

Dystonia
Focal Dystonia
Musician's Dystonia

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT02867592 | ACTIVE_NOT_RECRUITING | PHASE2

109 participants

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-05-18
Completion:: 2021-06-30

Conditions

Adrenal Cortical Carcinoma
Alveolar Soft Part Sarcoma
Central Nervous System Neoplasm
Childhood Clear Cell Sarcoma of Soft Tissue
Clear Cell Sarcoma of Soft Tissue
Ewing Sarcoma
Hepatoblastoma
Hepatocellular Carcinoma
Osteosarcoma
Recurrent Adrenal Cortical Carcinoma
Recurrent Alveolar Soft Part Sarcoma
Recurrent Clear Cell Sarcoma of Soft Tissue
Recurrent Ewing Sarcoma
Recurrent Hepatoblastoma
Recurrent Hepatocellular Carcinoma
Recurrent Kidney Wilms Tumor
Recurrent Malignant Solid Neoplasm
Recurrent Osteosarcoma
Recurrent Primary Malignant Central Nervous System Neoplasm
Recurrent Renal Cell Carcinoma
Recurrent Rhabdomyosarcoma
Recurrent Soft Tissue Sarcoma
Recurrent Thyroid Gland Medullary Carcinoma
Refractory Adrenal Cortical Carcinoma
Refractory Alveolar Soft Part Sarcoma
Refractory Clear Cell Sarcoma of Soft Tissue
Refractory Ewing Sarcoma
Refractory Hepatoblastoma
Refractory Hepatocellular Carcinoma
Refractory Malignant Solid Neoplasm
Refractory Osteosarcoma
Refractory Primary Central Nervous System Neoplasm
Refractory Primary Malignant Central Nervous System Neoplasm
Refractory Renal Cell Carcinoma
Refractory Rhabdomyosarcoma
Refractory Soft Tissue Sarcoma
Refractory Thyroid Gland Medullary Carcinoma
Refractory Wilms Tumor
Renal Cell Carcinoma
Rhabdomyosarcoma
Soft Tissue Sarcoma
Solid Neoplasm
Thyroid Gland Medullary Carcinoma
Wilms Tumor

Interventions

DRUG
OTHER

Results Available

NCT02858336 | COMPLETED | NA

38 participants

CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-01-12
Completion:: 2019-06-29

Conditions

Hormones

Interventions

BEHAVIORAL

No Results Yet

NCT02851706 | COMPLETED

1214 participants

Natural History of and Specimen Banking for People With Tumors of the Central Nervous System

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-09-01
Completion:: 2025-05-29

Conditions

Brain Cancer
Brain Tumor
Spine Cancer
Spine Tumor
Neoplasm

Interventions

OTHER

No Results Yet

NCT02849496 | ACTIVE_NOT_RECRUITING | PHASE2

89 participants

Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-03-30
Completion:: 2026-06-10

Conditions

Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Locally Advanced Unresectable Breast Carcinoma
Metastatic Breast Carcinoma

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT02840448 | COMPLETED

159 participants

Impact of Elastin Mediated Vascular Stiffness on End Organs

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-12-02
Completion:: 2024-04-06

Conditions

Williams Syndrome
Supravalvular Aortic Stenosis
Cardiovascular Disease

No Results Yet

NCT02839850 | ACTIVE_NOT_RECRUITING | NA

540 participants

14022 ATTUNE Cementless RP Clinical Performance Evaluation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-09-01
Completion:: 2027-09-01

Conditions

Osteoarthritis

Interventions

DEVICE

No Results Yet

NCT02839707 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

444 participants

Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2017-06-23
Completion:: 2023-05-09

Conditions

Fallopian Tube High Grade Serous Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Ovarian Seromucinous Carcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Fallopian Tube Clear Cell Adenocarcinoma
Recurrent Fallopian Tube Endometrioid Adenocarcinoma
Recurrent Fallopian Tube Undifferentiated Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Ovarian Clear Cell Adenocarcinoma
Recurrent Ovarian Endometrioid Adenocarcinoma
Recurrent Ovarian Undifferentiated Carcinoma
Recurrent Platinum-Resistant Fallopian Tube Carcinoma
Recurrent Platinum-Resistant Ovarian Carcinoma
Recurrent Platinum-Resistant Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Clear Cell Adenocarcinoma
Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
Recurrent Primary Peritoneal Undifferentiated Carcinoma

Interventions

DRUG
BIOLOGICAL
PROCEDURE
OTHER

Results Available

NCT02808780 | ACTIVE_NOT_RECRUITING

535 participants

An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-12-16
Completion:: 2026-12-10

Conditions

Ulcerative Colitis

No Results Yet

NCT02741440 | ACTIVE_NOT_RECRUITING

22 participants

Natural History of Spinocerebellar Ataxia Type 7 (SCA7)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-07-11
Completion:: 2028-12-31

Conditions

Spinocerebellar Ataxia

No Results Yet

NCT02724371 | ACTIVE_NOT_RECRUITING | NA

400 participants

A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-04-01
Completion:: 2029-01-31

Conditions

Breast Reconstruction
Revision Breast Reconstruction

Interventions

DEVICE

No Results Yet

NCT02706639 | COMPLETED

305 participants

Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-05-11
Completion:: 2025-03-07

Conditions

Williams Syndrome
Supravalvular Aortic Stenosis
Cardiovascular Disease

No Results Yet

NCT02659930 | ACTIVE_NOT_RECRUITING | PHASE1

62 participants

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-01-13
Completion:: 2028-01-01

Conditions

Kaposi Sarcoma

Interventions

DRUG

No Results Yet

NCT02639325 | RECRUITING

100 participants

Tumor Related Epilepsy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-01-26
Completion:: 2032-07-01

Conditions

Epilepsy
Cancer
Brain Neoplasm

No Results Yet

NCT02639312 | RECRUITING

2400 participants

Natural History of Craniofacial Anomalies and Developmental Growth Variants

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-04-18
Completion:: 2046-12-31

Conditions

Prognathism
Retrognathism
Dentofacial Deformities

No Results Yet

NCT02639299 | RECRUITING

1500 participants

Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-12-08
Completion:: 2030-09-30

Conditions

Malaria

No Results Yet

NCT02629107 | RECRUITING

2378 participants

Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-01-14
Completion:: 2044-12-31

Conditions

Normal Physiology

No Results Yet

NCT02609776 | ACTIVE_NOT_RECRUITING | PHASE1

751 participants

Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-05-24
Completion:: 2026-12-31

Conditions

Non-Small-Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT02595944 | ACTIVE_NOT_RECRUITING | PHASE3

903 participants

Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-07-22
Completion:: 2026-12-31

Conditions

Stage IB Lung Non-Small Cell Carcinoma AJCC v7
Stage II Lung Non-Small Cell Cancer AJCC v7
Stage IIIA Lung Non-Small Cell Cancer AJCC v7

Interventions

PROCEDURE
BIOLOGICAL
OTHER

No Results Yet

NCT02592317 | ACTIVE_NOT_RECRUITING | PHASE1

23 participants

A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-02-12
Completion:: 2016-11-07

Conditions

Prostatic Neoplasms, Castration-Resistant

Interventions

DRUG

No Results Yet

NCT02583646 | RECRUITING

150 participants

Investigating the Impact of Obesity on Pubertal Development in Girls

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-12-15
Completion:: 2026-09-30

Conditions

Obesity
Puberty
Normal Physiology

No Results Yet

NCT02567435 | ACTIVE_NOT_RECRUITING | PHASE3

325 participants

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2016-06-01
Completion:: 2023-06-30

Conditions

Alveolar Rhabdomyosarcoma
Botryoid-Type Embryonal Rhabdomyosarcoma
Embryonal Rhabdomyosarcoma
Rhabdomyosarcoma
Sclerosing Rhabdomyosarcoma
Spindle Cell Rhabdomyosarcoma

Interventions

DRUG
BIOLOGICAL
OTHER
RADIATION

Results Available

NCT02531516 | ACTIVE_NOT_RECRUITING | PHASE3

1503 participants

An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-11-19
Completion:: 2027-03-01

Conditions

Prostatic Neoplasms

Interventions

DRUG
RADIATION

No Results Yet

NCT02520609 | COMPLETED

53 participants

Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-10-28
Completion:: 2020-05-14

Conditions

Liver Disease
Fatty Liver

No Results Yet

NCT02506153 | ACTIVE_NOT_RECRUITING | PHASE3

1301 participants

Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-11-10
Completion:: 2023-09-15

Conditions

Clinical Stage III Cutaneous Melanoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Metastatic Cutaneous Melanoma
Metastatic Mucosal Melanoma
Metastatic Non-Cutaneous Melanoma
Non-Cutaneous Melanoma
Recurrent Cutaneous Melanoma
Recurrent Mucosal Melanoma
Recurrent Non-Cutaneous Melanoma

Interventions

PROCEDURE
BIOLOGICAL
OTHER

Results Available

NCT02504853 | RECRUITING

1800 participants

Natural History and Genetics of Food Allergy and Related Conditions

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-07-29
Completion:: 2027-06-15

Conditions

Food Allergy
Loeys-Dietz Syndrome
Atopic Dermatitis
Eosinophilic Esophagitis

No Results Yet

NCT02494986 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

A Roll-over Study With Rilpivirine for Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Who Participated in Rilpivirine Pediatric Studies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-07-06
Completion:: 2026-08-18

Conditions

Human Immunodeficiency Virus Type 1

Interventions

DRUG

No Results Yet

NCT02471365 | COMPLETED

11 participants

Study of Exposure to Chemicals in Consumer Products

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2018-08-07
Completion:: 2020-08-12

Conditions

Product Use

No Results Yet

NCT02471352 | RECRUITING

700 participants

Studies of Dermatologic Diseases Biospecimen Acquisition Protocol

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-06-19
Completion:: 2035-01-31

Conditions

Dermatologic Conditions
Healthy Volunteers
Normal Volunteers
Carcinoma, Merkel Cell

No Results Yet

NCT02465060 | ACTIVE_NOT_RECRUITING | PHASE2

6452 participants

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-08-17
Completion:: 2026-12-31

Conditions

Advanced Lymphoma
Advanced Malignant Solid Neoplasm
Bladder Carcinoma
Breast Carcinoma
Cervical Carcinoma
Colon Carcinoma
Colorectal Carcinoma
Endometrial Carcinoma
Esophageal Carcinoma
Exocrine Pancreas Carcinoma
Gastric Carcinoma
Glioma
Head and Neck Carcinoma
Hematopoietic and Lymphoid Cell Neoplasm
Kidney Carcinoma
Liver Carcinoma
Lung Carcinoma
Lymphoma
Malignant Uterine Corpus Neoplasm
Malignant Uterine Neoplasm
Melanoma
Multiple Myeloma
Ovarian Carcinoma
Prostate Carcinoma
Rectal Carcinoma
Recurrent Bladder Carcinoma
Recurrent Breast Carcinoma
Recurrent Cervical Carcinoma
Recurrent Colon Carcinoma
Recurrent Colorectal Carcinoma
Recurrent Esophageal Carcinoma
Recurrent Gastric Carcinoma
Recurrent Glioma
Recurrent Head and Neck Carcinoma
Recurrent Liver Carcinoma
Recurrent Lung Carcinoma
Recurrent Lymphoma
Recurrent Malignant Solid Neoplasm
Recurrent Malignant Uterine Corpus Neoplasm
Recurrent Melanoma
Recurrent Multiple Myeloma
Recurrent Ovarian Carcinoma
Recurrent Pancreatic Carcinoma
Recurrent Prostate Carcinoma
Recurrent Rectal Carcinoma
Recurrent Skin Carcinoma
Recurrent Thyroid Gland Carcinoma
Refractory Lymphoma
Refractory Malignant Solid Neoplasm
Refractory Multiple Myeloma
Skin Carcinoma
Thyroid Gland Carcinoma

Interventions

DRUG
PROCEDURE
OTHER
BIOLOGICAL

No Results Yet

NCT02450851 | RECRUITING

20000 participants

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-09-16
Completion:: 2028-12-31

Conditions

Genetic Disease

No Results Yet

NCT02446262 | RECRUITING | NA

550 participants

Neural and Psychological Mechanisms of Pain Perception

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-06-11
Completion:: 2027-02-20

Conditions

Pain
Normal Physiology
Healthy Volunteers

Interventions

BEHAVIORAL

No Results Yet

NCT02417740 | RECRUITING

400 participants

Natural History of Noncirrhotic Portal Hypertension

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-07-27
Completion:: 2029-09-04

Conditions

Cystic Fibrosis
Immunologic Deficiency Syndrome
Turner Syndrome
Congenital Hepatic Fibrosis
Idiopathic Non-Cirrhotic Portal Hypertension

No Results Yet

NCT02400216 | COMPLETED

30 participants

Deciphering the Mechanisms Involved in Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-05-29
Completion:: 2017-02-24

Conditions

Cirrhosis

Interventions

DRUG

No Results Yet

NCT02379429 | RECRUITING

500 participants

Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-11-10
Completion:: 2027-01-01

Conditions

Bladder Cancer
Urinary Tract Cancer
Urothelial Cancer
Healthy Volunteers

No Results Yet

NCT02365597 | ACTIVE_NOT_RECRUITING | PHASE2

239 participants

An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-28
Start Date:: 2015-04-22
Completion:: 2022-09-15

Conditions

Urothelial Cancer

Interventions

DRUG

Results Available