Clinical Trials Updated in 2026

NCT06233461 | RECRUITING | PHASE2

268 participants

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-03-05
Completion:: 2027-02-17

Conditions

Crohn's Disease

Interventions

DRUG

No Results Yet

NCT06229470 | ACTIVE_NOT_RECRUITING | NA

250 participants

Clinical Utility of Neurophysiological Measurements of ECAP-controlled Closed-loop SCS to Guide Treatment of Chronic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-03-08
Completion:: 2027-02-28

Conditions

Chronic Pain

Interventions

DEVICE

No Results Yet

NCT06225453 | RECRUITING | NA

1896 participants

Individualized Versus Conventional Perioperative Blood Pressure Management

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-01-29
Completion:: 2026-11-30

Conditions

Major Non-cardiac Surgery

Interventions

OTHER

No Results Yet

NCT06218485 | ACTIVE_NOT_RECRUITING | NA

1942 participants

FFR Versus IVUS With Angiography-Derived FFR for Clinical Outcomes in Patients With Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-03-13
Completion:: 2028-09-01

Conditions

Coronary Artery Disease

Interventions

PROCEDURE

No Results Yet

NCT06210555 | RECRUITING

96 participants

Multiparametric MRI in a Prospective Cohort of Living Kidney Donors, Recipients, and Healthy Controls: Correlations With Markers of Renal Function, Fibrosis and Ageing

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-10-29
Completion:: 2029-03-01

Conditions

Kidney Transplantation
Multiparametric Magnetic Resonance Imaging
Living Donors
Renal Fibrosis
Senescence

Interventions

PROCEDURE

No Results Yet

NCT06205511 | COMPLETED

300 participants

The Prevalence of Oral HPV Infection and Oral Lesions in People Living With HIV

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-04-01
Completion:: 2024-09-01

Conditions

Human Immunodeficiency Virus
Human Papilloma Virus

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06193252 | RECRUITING | NA

110 participants

Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-01-15
Completion:: 2028-12-01

Conditions

Parkinson Disease
Prodromal Stage
Neurodegenerative Diseases
Parkinsonian Disorders
REM Sleep Behavior Disorder
Basal Ganglia Diseases
Central Nervous System Diseases
Synucleinopathies
Nervous System Diseases
Cerebral Disorder
Brain Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT06192342 | RECRUITING

19 participants

Ventilatory Parameters in Acute Neurological Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-05-01
Completion:: 2027-05-30

Conditions

Neurologic Decompensation, Acute
Traumatic Brain Injury
Stroke
Subarachnoid Hemorrhage

No Results Yet

NCT06171178 | TERMINATED | PHASE1

15 participants

A Study of ASP1012 in Adults With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-05-15
Completion:: 2025-09-11

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06158841 | ACTIVE_NOT_RECRUITING | PHASE3

421 participants

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-05-19
Completion:: 2027-12-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06158815 | COMPLETED | NA

23 participants

Investigation of the Effects of Proprioceptive Neuromuscular Facilitation Exercises in Patients With Myasthenia Gravis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-11-23
Completion:: 2024-07-09

Conditions

Myasthenia Gravis

Interventions

OTHER

No Results Yet

NCT06143332 | RECRUITING | NA

105 participants

Domain-specific Aerobic Exercise Training in Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-11-01
Completion:: 2027-08-31

Conditions

Coronary Artery Disease

Interventions

OTHER

No Results Yet

NCT06136559 | RECRUITING | PHASE3

1200 participants

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-12-13
Completion:: 2032-09-07

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

DRUG

No Results Yet

NCT06136494 | ACTIVE_NOT_RECRUITING | NA

126 participants

iCBT for Cardiac Anxiety in Patients With NCCP

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-03-15
Completion:: 2026-06-01

Conditions

Non-cardiac Chest Pain
Cardiac Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT06130553 | RECRUITING | PHASE1/PHASE2

334 participants

A Study of AZD3470, a PRMT5 Inhibitor, Given as Monotherapy and in Combination in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-01-18
Completion:: 2028-12-04

Conditions

Advanced Solid Tumors That Are MTAP Deficient

Interventions

DRUG

No Results Yet

NCT06126601 | RECRUITING

150 participants

Incidence and Clinical Impact of Serum Hyperamylasemia (POH) After Pancreatectomy on Postoperative Outcome and Patient Safety

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-07-18
Completion:: 2026-12-31

Conditions

Pancreatectomy
Hyperamylasemia
Pancreatitis, Acute

Interventions

OTHER

No Results Yet

NCT06114511 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

78 participants

A Study of BL-M07D1 in Patients With HER2-mutated, Locally Advanced or Metastatic Non-small-cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-04-24
Completion:: 2026-12-31

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06100822 | TERMINATED | PHASE1

21 participants

Managing Chronic Tendon Pain by Metformin

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-05-24
Completion:: 2026-08-24

Conditions

Tendinopathy
Chronic Pain
Achilles Tendinopathy

Interventions

DRUG

No Results Yet

NCT06091930 | TERMINATED | PHASE1

21 participants

A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-02-16
Completion:: 2025-08-15

Conditions

Gastrointestinal Cancer
Lung Cancer
Pancreatic Cancer
Colorectal Cancer
Head and Neck Cancer
Liver Cancer

Interventions

DRUG

No Results Yet

NCT06082323 | COMPLETED | PHASE1

150 participants

A Single and Multiple Ascending Dose Trial of LT-002-158 Tablets in Healthy Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-06-13
Completion:: 2025-11-25

Conditions

Healthy Volunteer
Hidradenitis Suppurativa
Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06066203 | RECRUITING | PHASE1/PHASE2

40 participants

A Study of GNC-035 in Relapsed or Refractory Non-Hodgkin 's Lymphoma and Other Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-11-01
Completion:: 2026-12-31

Conditions

Non-hodgkin's Lymphoma

Interventions

DRUG

No Results Yet

NCT06053112 | COMPLETED | NA

326 participants

The Trial of a New Infant Formula in Healthy Term Chinese Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-11-12
Completion:: 2026-05-21

Conditions

Healthy Infants

Interventions

OTHER

No Results Yet

NCT06014580 | COMPLETED

276 participants

Molecular and Epidemiological Characteristics of Endometrial Cancer in Brazil

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-11-27
Completion:: 2024-10-31

Conditions

Endometrial Cancer

Interventions

OTHER

No Results Yet

NCT06003387 | RECRUITING | PHASE3

35 participants

Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-01-30
Completion:: 2028-10-04

Conditions

Hemophilia B

Interventions

GENETIC

No Results Yet

NCT06002399 | COMPLETED | NA

50 participants

Bilateral Monofocal Versus Monofocal-EDOF IOL Implantation: Quality of Vision Comparison

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-11-10
Completion:: 2025-12-31

Conditions

Cataract

Interventions

DEVICE

No Results Yet

NCT05995041 | NOT_YET_RECRUITING | PHASE1

30 participants

Universal CAR-T Cells Targeting AML

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2027-06-30
Completion:: 2029-12-31

Conditions

Acute Myeloid Leukemia

Interventions

BIOLOGICAL

No Results Yet

NCT05994443 | COMPLETED

120 participants

Fetal Brain Growth - Pilot Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-06-08
Completion:: 2025-12-01

Conditions

Preterm Labor
Maternal Psychological Distress

No Results Yet

NCT05985681 | RECRUITING | PHASE1

18 participants

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2026-01-27
Completion:: 2028-02-01

Conditions

Human Papillomavirus-Related Carcinoma

Interventions

PROCEDURE
BIOLOGICAL
OTHER

No Results Yet

NCT05965310 | RECRUITING | NA

60 participants

Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-09-01
Completion:: 2027-01-31

Conditions

Depression
Anterior Cruciate Ligament Injuries
Mental Health Issue

Interventions

BEHAVIORAL

No Results Yet

NCT05952258 | ENROLLING_BY_INVITATION | NA

220 participants

Magnetic Stimulation as a Treatment for Female Urinary Incontinence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-09-01
Completion:: 2027-07-31

Conditions

Stress Urinary Incontinence
Urgency Urinary Incontinence
Mixed Urinary Incontinence

Interventions

DEVICE

No Results Yet

NCT05947851 | RECRUITING | PHASE3

735 participants

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-08-08
Completion:: 2032-06-01

Conditions

Leukemia, Lymphocytic, Chronic, B-Cell
Leukemia, Chronic Lymphocytic
Small-Cell Lymphoma
Lymphoma, Small Lymphocytic
CLL
SLL

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05937269 | ACTIVE_NOT_RECRUITING | PHASE1

14 participants

Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-10-12
Completion:: 2026-08-31

Conditions

Lymphedema of Face
Head and Neck Cancer

Interventions

COMBINATION_PRODUCT
DEVICE

No Results Yet

NCT05924841 | RECRUITING | PHASE2

100 participants

A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Extensive Stage Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-11-10
Completion:: 2026-12-31

Conditions

Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05920356 | RECRUITING | PHASE3

750 participants

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-11-16
Completion:: 2027-06-30

Conditions

Non-Small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT05913713 | ACTIVE_NOT_RECRUITING | NA

158 participants

HIIT Following Breast Cancer Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-03-07
Completion:: 2026-12-31

Conditions

Breast Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05910567 | RECRUITING | NA

4650 participants

A Research Study of Abdominal Ultrasound (FAST) in Children With Blunt Torso Trauma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-04-17
Completion:: 2027-04-30

Conditions

Blunt Trauma to Abdomen
Wounds and Injuries
Abdomen Injury
Abdominal Injury
Abdomen, Acute

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT05904106 | RECRUITING | PHASE2

146 participants

Venetoclax Plus Azacitidine Versus Intensive Chemotherapy for Fit Patients With Newly Diagnosed NPM1 Mutated AML

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2024-04-07
Completion:: 2030-09-30

Conditions

Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT05902741 | RECRUITING | NA

300 participants

The Impact of a Race-Based Stress Reduction Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-10-18
Completion:: 2028-01-31

Conditions

Racism
Stress
Inflammation

Interventions

BEHAVIORAL

No Results Yet

NCT05898074 | RECRUITING | NA

30 participants

Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-10-09
Completion:: 2026-12-15

Conditions

Skull Base Neoplasms
Cerebrospinal Fluid Leakage
Nasal; Hypertrophy, Mucous Membrane (Septum)

Interventions

DEVICE

No Results Yet

NCT05895747 | RECRUITING | PHASE2

106 participants

5-HTP and Creatine for Depression R33 Phase

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-27
Start Date:: 2023-09-28
Completion:: 2027-07-01

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet