Clinical Trials

NCT06898086 | ENROLLING_BY_INVITATION | NA

620 participants

Transfemoral TAVI With or Without Coronary Angiogram in Patients With Severe Aortic Stenosis (PURE TAVI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-08-08

Completion:

2028-05-31

Conditions

• Severe Aortic Stenosis

Interventions

• DEVICE

No Results Yet

NCT06884865 | RECRUITING | PHASE2

135 participants

A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-02-26

Completion:

2026-11-30

Conditions

• Osteoarthritis (OA) of the Knee

Interventions

• BIOLOGICAL

No Results Yet

NCT06871878 | RECRUITING | NA

60 participants

Feasibility of a Physiotherapy Programme, With Integrated telerehabIlitation to Increase Rehabilitation Time and Improve Motor Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-12-01

Completion:

2027-07-10

Conditions

• Stroke Patients
• Stroke

Interventions

• OTHER

No Results Yet

NCT06861881 | NOT_YET_RECRUITING | NA

100 participants

Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary Bypass

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-09-30

Completion:

2026-10-31

Conditions

• Glucose Metabolism Disorders (Including Diabetes Mellitus)

Interventions

• DEVICE

No Results Yet

NCT06860022 | RECRUITING | NA

30 participants

Sentence Shaping - DHH

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-08-28

Completion:

2026-11-30

Conditions

• Hearing Loss, Bilateral

Interventions

• BEHAVIORAL

No Results Yet

NCT06859060 | RECRUITING | NA

300 participants

Improving Health and Wellness for People With Serious Mental Illness in Puerto Rico

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-09-01

Completion:

2029-02-28

Conditions

• Chronic Disease
• Serious Mental Illness

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06856343 | RECRUITING

126 participants

REBECCA Real-world Early BrEast CanCer mAnagement

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2024-12-30

Completion:

2028-01-31

Conditions

• Breast Cancer

No Results Yet

NCT06848244 | ACTIVE_NOT_RECRUITING | NA

100 participants

Preventing Type 2 Diabetes in Black Emergent Adult

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-06-30

Completion:

2030-12-31

Conditions

• Type 2 Diabetes Mellitus
• Binge-Eating Disorder
• Binge Eating
• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT06843070 | ACTIVE_NOT_RECRUITING

50 participants

Comparison of the Effects of Sacral Erector Spinae Plane Block and Dorsal Penile Block on Postoperative Pain in Circumcision Procedures

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2025-02-25

Completion:

2026-08-15

Conditions

• Postoperative Analgesia

Interventions

• PROCEDURE

No Results Yet

NCT06836440 | RECRUITING | NA

964 participants

Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-11-10

Completion:

2028-12-31

Conditions

• Cognition Disorders

Interventions

• DEVICE

No Results Yet

NCT06834594 | RECRUITING | PHASE4

40 participants

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-07-31

Completion:

2028-07-30

Conditions

• Turner Syndrome
• Primary Ovarian Insufficiency (Poi)

Interventions

• DRUG

No Results Yet

NCT06829017 | COMPLETED | NA

90 participants

Pilot Implementation of the Postoperative Hypothermia Management Care Bundle

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2026-01-01

Completion:

2026-06-20

Conditions

• Postoperative Hypothermia

Interventions

• OTHER

No Results Yet

NCT06823635 | RECRUITING

2000 participants

An International Multicenter Study on Transcatheter Device Closure of Perimembranous Ventricular Septal Defects

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2025-01-01

Completion:

2026-12-31

Conditions

• Perimembranous Ventricular Septal Defect

Interventions

• DEVICE

No Results Yet

NCT06821542 | ACTIVE_NOT_RECRUITING | PHASE3

9 participants

A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-06-04

Completion:

2028-05-31

Conditions

• Chronic Graft-versus-host-disease

Interventions

• DRUG

No Results Yet

NCT06820476 | COMPLETED | PHASE1

29 participants

A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants After 10 Days of Oral Dosing

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-02-09

Completion:

2025-05-14

Conditions

• Overweight
• Obesity

Interventions

• DRUG

No Results Yet

NCT06818812 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

A Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-03-27

Completion:

2027-03-27

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06811233 | RECRUITING | PHASE2

140 participants

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-05-08

Completion:

2029-08-31

Conditions

• Acute Myeloid Leukemia (AML)

Interventions

• DRUG

No Results Yet

NCT06807385 | COMPLETED | NA

26 participants

The Effect of the Reaction Training in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-02-17

Completion:

2025-11-05

Conditions

• Parkinson' Disease

Interventions

• OTHER

No Results Yet

NCT06804499 | RECRUITING

4000 participants

Tampere Coronary Artery Disease and Sudden Cardiac Arrest Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2025-01-13

Completion:

2027-12-31

Conditions

• Sudden Cardiac Arrest
• Sudden Cardiac Death
• Sudden Cardiac Death Due to Cardiac Arrhythmia
• Coronary Arterial Disease (CAD)
• Acute Coronary Event

No Results Yet

NCT06804122 | RECRUITING | NA

20 participants

Exercise-based Rehabilitation in Patients With Pulmonary Arterial Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-01-27

Completion:

2026-12-31

Conditions

• Pulmonary Arterial Hypertension

Interventions

• BEHAVIORAL

No Results Yet

NCT06799507 | RECRUITING | NA

92 participants

The Effect of Mindfulness-Based Lifestyle Support Program on Infertile Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-01-31

Completion:

2026-10-31

Conditions

• Fertility Disorders
• Infertility (IVF Patients)

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06797362 | AVAILABLE

Expanded Access Program of Zidesamtinib (NVL-520) for Patients With Advanced ROS1+ NSCLC or Other ROS1+ Solid Tumors

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-25

Conditions

• Non Small Cell Lung Cancer
• ROS1-positive Non-Small Cell Lung Cancer (NSCLC)

Interventions

• DRUG

No Results Yet

NCT06789913 | RECRUITING | PHASE2

277 participants

A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-06-13

Completion:

2031-07-31

Conditions

• PIK3CA-Related Overgrowth Spectrum (PROS)
• Lymphatic Malformations
• Vascular Malformations
• PIK3CA Mutation
• CLOVES Syndrome
• Klippel Trenaunay Syndrome
• Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)
• Vascular Anomalies

Interventions

• DRUG

No Results Yet

NCT06780098 | RECRUITING | PHASE2

144 participants

Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-05-28

Completion:

2032-03-02

Conditions

• Lung Neoplasm

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06780085 | RECRUITING | PHASE2

96 participants

A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-05-13

Completion:

2032-03-12

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06766175 | TERMINATED

60 participants

Impact of Refractory Chronic Cough on Activities of Daily Living and Response to Acute High-intensity Exercise

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2024-12-01

Completion:

2025-12-31

Conditions

• Chronic Cough (CC)
• Healthy Adult Participants

No Results Yet

NCT06765109 | RECRUITING | PHASE3

450 participants

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-07-17

Completion:

2029-12-31

Conditions

• Non-small Cell Lung Cancer
• Anaplastic Lymphoma Kinase-positive

Interventions

• DRUG

No Results Yet

NCT06748625 | ACTIVE_NOT_RECRUITING | PHASE3

370 participants

Efficacy of a Multidomain Intervention on Lifestyle Risk Factors for Dementia Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-03-13

Completion:

2026-03-23

Conditions

• Risk Behavior
• Cognitive Decline

Interventions

• BEHAVIORAL

No Results Yet

NCT06746285 | COMPLETED | NA

110 participants

Evaluating the Impact of Synbiotic Supplementation on Infants and Toddlers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-01-01

Completion:

2025-09-30

Conditions

• Gastrointestinal Tolerance of Probiotics in Infants

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT06741566 | COMPLETED | EARLY_PHASE1

150 participants

Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2024-12-27

Completion:

2026-05-14

Conditions

• Post Operative Cognitive Dysfunction

Interventions

• DRUG

No Results Yet

NCT06737029 | COMPLETED

311 participants

Alternative Diagnoses in Patients About to Start Empiric Tuberculosis Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2024-12-01

Completion:

2026-08-10

Conditions

• Tuberculosis
• Lung Diseases

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06727604 | RECRUITING | PHASE2

240 participants

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2024-12-17

Completion:

2028-06-30

Conditions

• Graves' Disease

Interventions

• DRUG

No Results Yet

NCT06723795 | ACTIVE_NOT_RECRUITING | NA

150 participants

Cardiovascular Assessment and Treatment During COPD Exacerbation to Improve Diagnosis and Outcomes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-03-01

Completion:

2026-07-25

Conditions

• COPD (Chronic Obstructive Pulmonary Disease)
• Cardiovascular Diseases

Interventions

• OTHER

No Results Yet

NCT06722118 | RECRUITING | PHASE3

348 participants

Corticosteroids Before Extubation in Pediatric Intensive Care Unit

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-10-28

Completion:

2028-10-31

Conditions

• Intensive Care Pediatric

Interventions

• DRUG
• OTHER

No Results Yet

NCT06719011 | COMPLETED | PHASE1

178 participants

A Study on How NNC0174-1213 Works in People With Overweight or Obesity.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2024-12-03

Completion:

2026-07-20

Conditions

• Obesity
• Overweight

Interventions

• DRUG

No Results Yet

NCT06716918 | COMPLETED

188 participants

Effect of Antenatal Corticosteroids on Neonatal Hypoglycemia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2025-01-14

Completion:

2025-12-10

Conditions

• Antenatal Corticosteroids

Interventions

• DRUG

No Results Yet

NCT06716671 | COMPLETED

87 participants

Influence of Continuous Glucose Monitoring on Quality of Life in People With Type 2 Diabetes Mellitus

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-25

Start Date:

2024-09-04

Completion:

2026-05-31

Conditions

• Continuous Glucose Monitoring
• Quality of Life
• Type 2 Diabetes Mellitus (T2DM)

No Results Yet

NCT06705491 | ACTIVE_NOT_RECRUITING | NA

100 participants

Trauma-Informed Procedural Pain Intervention: Refinement of an Evidence-Based Protocol

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-02-07

Completion:

2026-06-30

Conditions

• Procedural Pain
• Cancer-related Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT06698796 | RECRUITING | PHASE3

211 participants

A Study to Understand How the Study Medicine Dazukibart Works in People With Idiopathic Inflammatory Myopathies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-01-22

Completion:

2031-07-29

Conditions

• Dermatomyositis
• Polymyositis

Interventions

• DRUG

No Results Yet

NCT06698549 | COMPLETED | PHASE1

12 participants

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ALG-097558 in Subjects With Renal Impairment and in Healthy Subjects With Normal Renal Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-25

Start Date:

2025-02-20

Completion:

2025-07-23

Conditions

• COVID 19

Interventions

• DRUG

Results Available