Clinical Trials Updated in 2026

NCT06619587 | RECRUITING | PHASE1

410 participants

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-11-14
Completion:: 2028-05-31

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06617858 | RECRUITING | PHASE2

15 participants

Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-12-04
Completion:: 2028-02-01

Conditions

Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT06601465 | RECRUITING | PHASE2

120 participants

COgnitioN With VERiciGuat Evaluation in Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-06-03
Completion:: 2028-07-16

Conditions

Heart Failure
Cognitive Impairment

Interventions

DRUG

No Results Yet

NCT06600139 | COMPLETED | NA

210 participants

Screening to Identify Parents in Need of Mental Health Support: A Feasibility Study in Child Welfare Services

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-10-09
Completion:: 2026-05-05

Conditions

Mental Disorder
Depression
Anxiety
Child Abuse
Child Neglect
Child Maltreatment

Interventions

BEHAVIORAL

No Results Yet

NCT06594939 | RECRUITING | PHASE2

31 participants

Mosunetuzumab and Polatuzumab Vedotin With Split-Dose CHP Chemotherapy for Elderly Patients With Diffuse Large B-Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2026-06-01
Completion:: 2028-06-30

Conditions

Diffuse Large B Cell Lymphoma (DLBCL)

Interventions

DRUG
OTHER

No Results Yet

NCT06592014 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

35 participants

Lithium for Parkinson's: an Extension Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-08-09
Completion:: 2026-10-01

Conditions

Parkinson Disease

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06590818 | COMPLETED | NA

50 participants

The Effect of Body Mass Index on Short-term Results of HTO

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-07-10
Completion:: 2025-07-01

Conditions

Osteo Arthritis Knee
Varus Knee

Interventions

PROCEDURE

No Results Yet

NCT06586190 | NOT_YET_RECRUITING | NA

20 participants

Outpatient Floor Pedal Bike Utilization

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2026-10-31
Completion:: 2028-12-31

Conditions

Femur Fracture
Tibia Fracture
Ankle Injuries

Interventions

OTHER

No Results Yet

NCT06580210 | RECRUITING

114 participants

Performance and Safety Assessment of the Mechanical Decongestant Seawater Spray Enriched With Essential Oils From Laboratoires Gilbert in Patient With Acute Rhinitis Associated With Nasal Obstruction

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-10-22
Completion:: 2026-11-30

Conditions

Acute Rhinitis
Nasal Obstruction
Rhinosinusitis
Rhinopharyngitis
Allergic Rhinitis

No Results Yet

NCT06572865 | COMPLETED

155 participants

Identifying Parents in Child Welfare Services Who Need Mental Health Support: Depression and Anxiety Symptoms

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-11-29
Completion:: 2026-05-05

Conditions

Mental Illness
Depression
Anxiety

Interventions

OTHER

No Results Yet

NCT06563258 | COMPLETED | NA

60 participants

Efficacy of Biodex Balance Training Versus Whole Body Vibration Training in Patients With Knee Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-09-01
Completion:: 2025-03-30

Conditions

Knee Osteoarthritis

Interventions

DEVICE
OTHER

No Results Yet

NCT06562439 | WITHDRAWN | NA

0 participants

Testing the Sickle Cell Caregiver Collaboration for Child Development (SCCCD) Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-07-01
Completion:: 2028-01-31

Conditions

Sickle Cell Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06557798 | RECRUITING

550 participants

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-12-12
Completion:: 2027-06-30

Conditions

Aortic Valve Stenosis

Interventions

DEVICE
PROCEDURE
OTHER

No Results Yet

NCT06548152 | RECRUITING

120 participants

AQUALIS:QoL of CLL Patients Treated With Acalabrutinib in France, Retrospective Study Based on Data From PLATON Database

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-04-28
Completion:: 2026-12-31

Conditions

Chronic Lymphocytic Leukemia

No Results Yet

NCT06545682 | RECRUITING | PHASE1

50 participants

Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-10-15
Completion:: 2027-08-03

Conditions

Melanoma (Skin Cancer)
Breast Cancer
Brain Metastasases

Interventions

DRUG

No Results Yet

NCT06541704 | RECRUITING | PHASE3

975 participants

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-10-30
Completion:: 2028-07-31

Conditions

Age-related Macular Degeneration (AMD)
Geographic Atrophy (GA)

Interventions

DRUG

No Results Yet

NCT06536049 | RECRUITING | PHASE1/PHASE2

38 participants

Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-04-02
Completion:: 2027-08-31

Conditions

Recurrent Diffuse Large B-Cell Lymphoma
Recurrent Grade 3b Follicular Lymphoma
Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified
Recurrent Primary Mediastinal Large B-Cell Lymphoma
Recurrent Transformed Non-Hodgkin Lymphoma
Refractory Diffuse Large B-Cell Lymphoma
Refractory Grade 3b Follicular Lymphoma
Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified
Refractory Primary Mediastinal Large B-Cell Lymphoma
Refractory Transformed Non-Hodgkin Lymphoma

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT06533761 | RECRUITING | PHASE1

125 participants

Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-04-28
Completion:: 2027-07-15

Conditions

AML, Adult
MDS

Interventions

DRUG

No Results Yet

NCT06532890 | RECRUITING

150 participants

Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-02-06
Completion:: 2029-10-01

Conditions

Cardiac Failure
Graft Rejection

No Results Yet

NCT06530485 | COMPLETED | NA

154 participants

Post Discharge Trial to Enhance Immunity in Severely Malnourished Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-09-01
Completion:: 2025-12-31

Conditions

Child Malnutrition

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06517693 | RECRUITING | PHASE1

48 participants

Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2026-01-05
Completion:: 2027-12-31

Conditions

HIV-1

Interventions

DRUG

No Results Yet

NCT06516575 | RECRUITING | NA

400 participants

Listening Effort in Cochlear Implant Users

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2023-09-01
Completion:: 2028-04-28

Conditions

Auditory Perception; Abnormal
Hearing Loss, Sensorineural
Hearing Loss

Interventions

BEHAVIORAL

No Results Yet

NCT06515743 | COMPLETED

42 participants

Rehabilitation With an Obturator in Maxillary Defects

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-06-01
Completion:: 2024-09-20

Conditions

Mucormycosis

Interventions

OTHER

No Results Yet

NCT06514261 | SUSPENDED | PHASE1

45 participants

Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-12-18
Completion:: 2027-09-16

Conditions

Acute Myeloid Leukemia

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06496867 | SUSPENDED | NA

48 participants

Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-11-12
Completion:: 2026-12-21

Conditions

Multiple Closed Pelvic Fractures With Disruption of Pelvic Ring
Fragility Fracture
Internal Fixation
Nonoperative Care

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06489015 | COMPLETED | EARLY_PHASE1

30 participants

Recombinant Human Serum Albumin in the Treatment of Mild-to-moderate AD (Alzheimer's Disease) Exploratory Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-08-27
Completion:: 2026-04-14

Conditions

Alzheimer's Disease (AD)

Interventions

DRUG

No Results Yet

NCT06470022 | ACTIVE_NOT_RECRUITING | NA

1370 participants

Comparison of Evolut FX Versus Sapien 3 Ultra Resilia.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-08-09
Completion:: 2027-07-14

Conditions

Aortic Stenosis

Interventions

DEVICE

No Results Yet

NCT06452355 | COMPLETED | NA

73 participants

Safety and Effectiveness of the KOKO Device to Treat Primary Abnormal Postpartum Uterine Bleeding or Hemorrhage

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-08-29
Completion:: 2026-07-29

Conditions

Postpartum Hemorrhage
Immediate Postpartum Hemorrhage
Hemorrhage, Postpartum

Interventions

DEVICE

No Results Yet

NCT06427876 | ACTIVE_NOT_RECRUITING

40 participants

Fasenra Pediatric Japan Post-Marketing Study(PMS)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-07-16
Completion:: 2028-12-31

Conditions

Bronchial Asthma

No Results Yet

NCT06416657 | RECRUITING | NA

188 participants

General Anesthesia vs Local Anesthesia for Endovascular Treatment in Patients With Unruptured Intracranial Aneurysm Using Flow Diverter

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-06-01
Completion:: 2026-11-12

Conditions

Intracranial Aneurysm

Interventions

OTHER

No Results Yet

NCT06414317 | ACTIVE_NOT_RECRUITING | NA

12 participants

An Education and Navigation Support Tool to Improve Participation in Care Coordination Among Patients With Locally Advanced, Metastatic and Unresectable Bladder Cancer and Their Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-01-12
Completion:: 2026-09-30

Conditions

Locally Advanced Bladder Carcinoma
Metastatic Bladder Carcinoma
Stage III Bladder Cancer AJCC v8
Stage IV Bladder Cancer AJCC v8
Unresectable Bladder Carcinoma

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06401330 | RECRUITING | PHASE3

1656 participants

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-04-15
Completion:: 2031-02-13

Conditions

Stage I Mixed Cell Type Kidney Wilms Tumor
Stage II Mixed Cell Type Kidney Wilms Tumor
Stage III Mixed Cell Type Kidney Wilms Tumor
Stage IV Mixed Cell Type Kidney Wilms Tumor

Interventions

PROCEDURE
DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT06396208 | COMPLETED | NA

40 participants

"Quick-starting" of a Quadriphasic Contraceptive Pills, 1 - 3 mg Estradiol Valerate/ 2 - 3 mg Dienogest VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-05-09
Completion:: 2024-10-20

Conditions

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities
Cervical Mucus
Serum Hormonal Profile

Interventions

DRUG

No Results Yet

NCT06387394 | COMPLETED | PHASE3

202 participants

A Study to Assess BOTOX Injections in Adult Participants for the Change of Masseter Muscle Prominence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-04-22
Completion:: 2025-11-25

Conditions

Masseter Muscle Prominence

Interventions

DRUG

No Results Yet

NCT06385028 | ACTIVE_NOT_RECRUITING | NA

150 participants

Physical Activity Promotion in Osteoarthritis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-02-13
Completion:: 2026-06-30

Conditions

Osteoarthritis

Interventions

BEHAVIORAL

No Results Yet

NCT06384872 | ACTIVE_NOT_RECRUITING | NA

1068 participants

Effect of Shoe Cushioning Position and Properties on Running-related Injury Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2025-04-01
Completion:: 2026-08-30

Conditions

Running-related Injury

Interventions

OTHER

No Results Yet

NCT06368817 | RECRUITING | PHASE2

240 participants

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-10-22
Completion:: 2033-11-04

Conditions

Basal Ganglia Germinoma
Diabetes Insipidus
Germinoma
Pineal Region Germinoma
Suprasellar Germinoma
Thalamic Germinoma

Interventions

RADIATION
PROCEDURE
DRUG
OTHER

No Results Yet

NCT06366464 | RECRUITING | PHASE3

134 participants

A Study of Pitolisant in Patients With Prader-Willi Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-05-28
Completion:: 2027-04-30

Conditions

Prader-Willi Syndrome

Interventions

DRUG
OTHER

No Results Yet

NCT06360406 | RECRUITING

200 participants

Real-World Treatment Study of Koselugo (Selumetinib)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-06-15
Completion:: 2031-09-30

Conditions

Neurofibromatosis 1
Neurofibroma, Plexiform

No Results Yet

NCT06350513 | COMPLETED | NA

40 participants

The Effect of Animated Movies and Storybooks on Fear and Anxiety Levels in Children With Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-25
Start Date:: 2024-02-25
Completion:: 2026-06-25

Conditions

Diabetes Mellitus, Type 1
Child, Only
Anxiety
Fear
Nurse

Interventions

OTHER

No Results Yet