Clinical Trials

NCT06664502 | COMPLETED | PHASE1/PHASE2

38 participants

A 2-part Study Consisting of a Multiple Ascending Dose Safety Study in Participants With Macular Edema Following Branch Retinal Vein Occlusion and a Dose-finding Safety and Preliminary Efficacy Study in Participants With Either Diabetic Macular Edema or Neovascular Age-related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-12

Completion:

2026-03-25

Conditions

• Diabetic Macular Edema (DME)
• Neovascular Age-related Macular Degeneration (NVAMD)
• BRVO - Branch Retinal Vein Occlusion

Interventions

• DRUG

No Results Yet

NCT06658574 | COMPLETED | PHASE2

65 participants

Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-13

Completion:

2026-05-02

Conditions

• Post Operative Analgesia
• Bariatric Surgery
• Bariatric Surgery (Gastric Bypass)
• Bariatric Surgery Patients
• Perioperative Analgesia

Interventions

• DRUG

Results Available

NCT06655025 | COMPLETED | NA

32 participants

The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-10-08

Completion:

2024-09-08

Conditions

• Cardiac Surgery
• Postoperative Cognitive Dysfunction
• Neurologic Manifestations

Interventions

• DRUG

No Results Yet

NCT06637020 | COMPLETED | PHASE1

80 participants

Phase Ib Clinical Study of HDM1005 Injection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-06-21

Completion:

2025-03-28

Conditions

• Overweight and Obesity

Interventions

• DRUG

No Results Yet

NCT06633978 | ACTIVE_NOT_RECRUITING | NA

90 participants

Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-09-10

Completion:

2026-08-31

Conditions

• MCI
• Aging

Interventions

• DEVICE

No Results Yet

NCT06633952 | ACTIVE_NOT_RECRUITING | NA

90 participants

Accelerating Cognitive Gains From Digital Inverventions With Noninvasive Brain Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-08-31

Completion:

2026-08-31

Conditions

• Aging
• MCI

Interventions

• DEVICE

No Results Yet

NCT06629779 | RECRUITING | PHASE3

900 participants

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-10-22

Completion:

2026-12-02

Conditions

• Metastatic Castration-Resistant Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT06627569 | NOT_YET_RECRUITING | NA

132 participants

Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-09-01

Completion:

2030-08-30

Conditions

• Overweight/Obesity
• Stress

Interventions

• BEHAVIORAL

No Results Yet

NCT06626334 | TERMINATED | NA

27 participants

Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-10-23

Completion:

2026-04-25

Conditions

• Rib Fractures
• Pain, Acute

Interventions

• DEVICE

No Results Yet

NCT06622174 | RECRUITING | PHASE1

32 participants

Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-08-20

Completion:

2028-07-31

Conditions

• Non Small Cell Lung Cancer
• Metastatic Lung Cancer

Interventions

• RADIATION

No Results Yet

NCT06621316 | COMPLETED | PHASE1/PHASE2

74 participants

A Study of Safety and Tolerability of Multiple Doses of HRS-7535 in Obese Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-10-30

Completion:

2025-07-14

Conditions

• Overweight or Obesity

Interventions

• DRUG

No Results Yet

NCT06620302 | SUSPENDED | PHASE1/PHASE2

81 participants

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-06-12

Completion:

2031-12-30

Conditions

• Childhood Fibrolamellar Carcinoma
• Recurrent Childhood Fibrolamellar Carcinoma
• Recurrent Childhood Malignant Solid Neoplasm
• Recurrent Fibrolamellar Carcinoma
• Recurrent Malignant Solid Neoplasm
• Refractory Childhood Fibrolamellar Carcinoma
• Refractory Childhood Malignant Solid Neoplasm
• Refractory Fibrolamellar Carcinoma
• Refractory Malignant Solid Neoplasm

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT06590857 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

16 participants

Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-07-19

Completion:

2028-10-31

Conditions

• Metastatic Breast Cancer
• HER2-negative Breast Cancer
• ER+ Breast Cancer
• Advanced Breast Cancer
• Metastatic Breast Cancer With Bone Involvement
• Bone Metastases in Subjects With Advanced Breast Cancer
• ER-Positive HER2-Negative Breast Cancer
• Estrogen Receptor-positive Breast Cancer
• Hormone-sensitive Metastatic Breast Cancer
• Hormone-Sensitive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06586515 | RECRUITING | PHASE1

630 participants

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-09-12

Completion:

2029-03-31

Conditions

• Pancreatic Ductal Adenocarcinoma
• Non-small Cell Lung Cancer
• Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT06581861 | RECRUITING

600 participants

PREVENT ALL ALS Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2024-07-25

Completion:

2029-01-31

Conditions

• Amyotrophic Lateral Sclerosis

No Results Yet

NCT06578195 | RECRUITING

2000 participants

ASSESS ALL ALS Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2024-07-25

Completion:

2029-01-31

Conditions

• Amyotrophic Lateral Sclerosis

No Results Yet

NCT06568627 | RECRUITING | PHASE3

216 participants

A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-06-01

Completion:

2026-12-31

Conditions

• Venous Leg Ulcer (VLU)

Interventions

• DRUG

No Results Yet

NCT06552741 | RECRUITING

10000 participants

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2024-09-04

Completion:

2045-01-01

Conditions

• Substance Use Disorder
• Alcohol Use Disorder

No Results Yet

NCT06520085 | RECRUITING | NA

170 participants

Optimizing Recovery After Reverse Shoulder Arthroplasty With a Personalized Mobile Health Application

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-09-01

Completion:

2027-07-01

Conditions

• Shoulder Osteoarthritis

Interventions

• OTHER

No Results Yet

NCT06512883 | RECRUITING | PHASE3

14 participants

A Trial to Investigate Benralizumab in Children With Eosinophilic Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-04-17

Completion:

2028-02-20

Conditions

• Eosinophilic Granulomatosis With Polyangiitis (EGPA)
• Hypereosinophilia Syndrome (HES)

Interventions

• DRUG

No Results Yet

NCT06509789 | RECRUITING | NA

100 participants

Priming Theta Burst Stimulation for Stroke: A Study of Intensity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-07-02

Completion:

2026-12-31

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT06506877 | ENROLLING_BY_INVITATION | NA

50 participants

A Cognitive Risk Calculator and Screening Tool for Primary Care Settings

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-04-03

Completion:

2027-09-01

Conditions

• Cognitive Risk Assessment

Interventions

• BEHAVIORAL

No Results Yet

NCT06502171 | RECRUITING | PHASE1

30 participants

Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-09

Completion:

2033-08-01

Conditions

• Neurofibromatosis 1
• Plexiform Neurofibroma

Interventions

• DRUG

No Results Yet

NCT06501118 | RECRUITING | NA

3600 participants

Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-09-01

Completion:

2026-09-01

Conditions

• Respiratory Failure
• Acute Hypoxemic Respiratory Failure
• Acute Hypoxic Respiratory Failure
• Hypoxemia
• Hypoxia
• Hypoxic Respiratory Failure

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT06493175 | COMPLETED | NA

1189 participants

The Application of Large Language Model in Emergency Chest Pain Triage

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2023-12-20

Completion:

2026-08-20

Conditions

• Chest Pain

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06479668 | COMPLETED | NA

30 participants

Characterize the Links Between Sleep, Emotional Dysregulation and Learning in Neurodevelopmental Disorders.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-10-03

Completion:

2026-05-13

Conditions

• Attention Deficit Disorder With or Without Hyperactivity (ADHD)
• Autism Spectrum Disorder (ASD)

Interventions

• BEHAVIORAL

No Results Yet

NCT06478979 | COMPLETED | NA

20 participants

The Pilot Study of Medical Device-Neuclare for Patients With Idiopathic Normal Pressure Hydrocephalus (iNPH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-07-22

Completion:

2025-11-21

Conditions

• Idiopathic Normal Pressure Hydrocephalus (iNPH)

Interventions

• DEVICE

No Results Yet

NCT06474026 | RECRUITING | NA

15 participants

Bilateral Nucleus Accumbens Focused Ultrasound Neuromodulation for Stimulant Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-07-01

Completion:

2027-07-31

Conditions

• Psychostimulant Use Disorder(PUD)

Interventions

• DEVICE

No Results Yet

NCT06465329 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-11-18

Completion:

2027-05-20

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT06459271 | RECRUITING | NA

50 participants

Feasibility of CALM in Patients With Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-06-10

Completion:

2027-02-28

Conditions

• Patient Satisfaction
• Ovarian Cancer

Interventions

• OTHER

No Results Yet

NCT06450925 | RECRUITING | PHASE2

190 participants

Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-03-25

Completion:

2027-08-31

Conditions

• Graft Vs Host Disease
• Vitamin A Deficiency
• Vitamin D Deficiency

Interventions

• DRUG
• OTHER

No Results Yet

NCT06441214 | ACTIVE_NOT_RECRUITING

212 participants

Retrospective-prospective Study to Evaluate Treatment Management and Outcomes of Patients With Waldenström's Macroglobulinemia (WM) Treated in Italy According to the Zanubrutinib (Brukinsa®) Compassionate Use Program (CUP) and in Common Practice Following Commercial Approval.

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2024-12-13

Completion:

2026-12-31

Conditions

• Waldenström's Macroglobulinemia (WM)

Interventions

• DRUG

No Results Yet

NCT06432166 | NOT_YET_RECRUITING | PHASE1/PHASE2

48 participants

2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-09-01

Completion:

2028-12-30

Conditions

• Alzheimer Disease
• Mild Cognitive Impairment

Interventions

• DRUG
• OTHER

No Results Yet

NCT06427486 | COMPLETED | NA

26 participants

Telecoaching Intervention for Children With Autism and Their Parents in Palestine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-02-15

Completion:

2025-06-21

Conditions

• Autism Spectrum Disorder

Interventions

• OTHER

No Results Yet

NCT06424184 | RECRUITING | NA

40 participants

Accelerated rTMS for Substance Use Disorder and Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-06-25

Completion:

2027-06-30

Conditions

• Stimulant Use
• Depression

Interventions

• DEVICE

No Results Yet

NCT06417554 | RECRUITING | PHASE1/PHASE2

80 participants

A Trial of SHR-A2102 With or Without Antitumor Therapy in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-05-27

Completion:

2031-12-31

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06397469 | RECRUITING | NA

4000 participants

Enhancing Attention and Wellbeing Using Digital Therapeutics

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-04-01

Completion:

2029-01-01

Conditions

• Aging
• MCI
• Cognitive Decline

Interventions

• DEVICE

No Results Yet

NCT06395753 | COMPLETED | PHASE2

55 participants

A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2024-05-23

Completion:

2026-06-24

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT06386107 | RECRUITING | NA

212 participants

Thrombin Generation Parameters and Bleeding in Patients Treated With Anticoagulants for Cancer Associated Thrombosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-09-02

Completion:

2027-07-31

Conditions

• Cancer
• Pulmonary Embolism
• Thrombosis

Interventions

• BIOLOGICAL

No Results Yet

NCT06385262 | SUSPENDED | PHASE2

63 participants

TOP 2301: Neoadjuvant Chemo for NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-03-17

Completion:

2028-10-30

Conditions

• Non Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet