Clinical Trials

NCT04214392 | ACTIVE_NOT_RECRUITING | PHASE1

19 participants

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2020-02-26

Completion:

2027-08-20

Conditions

• Recurrent Glioblastoma
• Recurrent Malignant Glioma
• Recurrent WHO Grade II Glioma
• Recurrent WHO Grade III Glioma

Interventions

• BIOLOGICAL

No Results Yet

NCT04178174 | RECRUITING | PHASE3

360 participants

Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2020-02-23

Completion:

2028-12-31

Conditions

• Head and Neck Cancer
• Oropharynx Cancer
• Human Papilloma Virus

Interventions

• RADIATION

No Results Yet

NCT04158739 | ACTIVE_NOT_RECRUITING | PHASE1

16 participants

Flotetuzumab for the Treatment of Pediatric Recurrent or Refractory Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2020-01-22

Completion:

2022-09-30

Conditions

• Recurrent Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04147468 | SUSPENDED | NA

10 participants

Functional Strength Training and Virtual Reality in Children With CP

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-08-16

Completion:

2022-06-30

Conditions

• Cerebral Palsy

Interventions

• OTHER

No Results Yet

NCT04085159 | TERMINATED | PHASE1/PHASE2

100 participants

Immunotherapy Based on Antigen-specific Immune Effector Cells Targeting Neurofibromatosis or Schwannomatosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04073745 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

Single Fraction Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-12-04

Completion:

2025-08-11

Conditions

• Lung Non-Small Cell Carcinoma
• Positive Surgical Margin
• Resected Mass
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• OTHER
• RADIATION

No Results Yet

NCT04071769 | COMPLETED | PHASE2

34 participants

Genentech Xenon MRI Idiopathic Pulmonary Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2020-08-03

Completion:

2024-10-17

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

• DRUG

Results Available

NCT04019327 | TERMINATED | PHASE1/PHASE2

16 participants

A Study of the Drugs Talazoparib and Temozolomide in Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-07-11

Completion:

2025-12-04

Conditions

• Prostate Cancer
• Prostate Adenocarcinoma
• Prostate Neoplasm
• Prostate Cancer Metastatic
• Castration-resistant Prostate Cancer

Interventions

• DRUG

Results Available

NCT04010877 | TERMINATED | PHASE1/PHASE2

10 participants

Multiple CAR-T Cell Therapy Targeting AML

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-08-01

Completion:

2026-07-01

Conditions

• Acute Myeloid Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT03952624 | ACTIVE_NOT_RECRUITING

37 participants

Patient-Centered Assessment of Symptoms and Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2019-09-13

Completion:

2027-06-01

Conditions

• Fatigue
• Cancer
• CFS
• ME/CFS
• Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
• Lupus
• Systemic Lupus Erthematosus
• Sjogrens

No Results Yet

NCT03902600 | COMPLETED

103 participants

A Study of Photon and Proton Chemoradiotherapy as Definitive or Neoadjuvant Therapy in Non-Metastatic Pancreatic Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2018-05-10

Completion:

2021-11-11

Conditions

• Pancreatic Cancer

Interventions

• RADIATION

No Results Yet

NCT03886168 | COMPLETED | NA

47 participants

Pediatric Image-Guided Cochlear Implant Programming

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-06-30

Completion:

2025-03-31

Conditions

• Cochlear Implant

Interventions

• OTHER

Results Available

NCT03848312 | ACTIVE_NOT_RECRUITING | PHASE3

7600 participants

Preventing Alzheimer's With Cognitive Training

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-02-19

Completion:

2028-01-31

Conditions

• Age-related Cognitive Decline
• Alzheimer's Disease and Related Dementias

Interventions

• BEHAVIORAL

No Results Yet

NCT03801876 | ACTIVE_NOT_RECRUITING | PHASE3

300 participants

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-06-26

Completion:

2031-11-07

Conditions

• Clinical Stage I Esophageal Adenocarcinoma AJCC v8
• Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8
• Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage II Esophageal Adenocarcinoma AJCC v8
• Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8
• Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Thoracic Esophagus Squamous Cell Carcinoma

Interventions

• PROCEDURE
• DRUG
• RADIATION
• OTHER

No Results Yet

NCT03773965 | RECRUITING | PHASE3

190 participants

A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-04-05

Completion:

2031-07-31

Conditions

• Juvenile Idiopathic Arthritis

Interventions

• DRUG

No Results Yet

NCT03570632 | COMPLETED | PHASE4

24 participants

Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2019-07-08

Completion:

2025-10-30

Conditions

• Diabetes Mellitus, Type 1
• Pregnancy in Diabetes

Interventions

• DRUG

No Results Yet

NCT03552016 | WITHDRAWN | PHASE2

0 participants

Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2018-10-10

Completion:

2021-12-13

Conditions

• Axial Myopia
• Refractive Errors

Interventions

• DRUG

No Results Yet

NCT03535246 | TERMINATED | PHASE1/PHASE2

100 participants

Immunotherapy Based on Tumor Associated Antigen-specific Immune Effector Cells

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-07-01

Completion:

2026-07-01

Conditions

• Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03460977 | RECRUITING | PHASE1

453 participants

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2018-04-17

Completion:

2028-04-20

Conditions

• Metastatic Castration Resistant Prostate Cancer (mCRPC)
• Small Cell Lung Cancer (SCLC)
• Follicular Lymphoma (FL)

Interventions

• DRUG

No Results Yet

NCT03458962 | ACTIVE_NOT_RECRUITING

1000 participants

Diagnostic Odyssey: Whole Genome Sequencing (WGS)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-24

Start Date:

2018-02-20

Completion:

2070-02-20

Conditions

• Genetic Disease
• Genetic Syndrome

Interventions

• GENETIC

No Results Yet

NCT03412877 | RECRUITING | PHASE2

285 participants

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2018-09-06

Completion:

2028-03-23

Conditions

• Endocrine Tumors
• Non-Small Cell Lung Cancer
• Ovarian Cancer
• Breast Cancer
• Gastrointestinal/Genitourinary Cancers
• Neuroendocrine Tumors
• Multiple Myeloma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03410875 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

A Phase II Study of the BRAF Inhibitor, Vemurafenib, Plus Obinutuzumab in Patients With Previously Untreated Classical Hairy Cell Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2018-02-09

Completion:

2027-01-31

Conditions

• Hairy Cell Leukemia
• Leukemia
• Leukemia, Hairy Cell

Interventions

• DRUG

No Results Yet

NCT03399110 | COMPLETED | PHASE3

1024 participants

XELOX for 4 Months Versus 6 Months in Gastric Cancer (LOMAC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2018-01-14

Completion:

2026-08-15

Conditions

• Gastric Cancer

Interventions

• DRUG

No Results Yet

NCT03362619 | TERMINATED | PHASE1/PHASE2

20 participants

Engineered Immune Effectors Against Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Cervical Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03362606 | TERMINATED | PHASE1/PHASE2

20 participants

Engineered Immune Effectors Against Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Ovarian Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03356795 | TERMINATED | PHASE1/PHASE2

20 participants

Intervention of CAR-T Against Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Cervical Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03351868 | TERMINATED | NA

10 participants

FANCA Gene Transfer for Fanconi Anemia Using a High-safety, High-efficiency, Self-inactivating Lentiviral Vector

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Fanconi Anemia

Interventions

• GENETIC

No Results Yet

NCT03351855 | TERMINATED | PHASE1/PHASE2

100 participants

HPV Specific Immune Lymphocytes (HPV-CTLs) in the Treatment of HPV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Human Papilloma Virus

Interventions

• BIOLOGICAL

No Results Yet

NCT03286335 | RECRUITING | NA

100 participants

Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2018-09-26

Completion:

2027-09-30

Conditions

• Brain Tumor

Interventions

• RADIATION

No Results Yet

NCT03263247 | ACTIVE_NOT_RECRUITING | NA

60 participants

Cognitive Training in Patients With MCI Using fMRI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2017-01-02

Completion:

2026-12-31

Conditions

• Mild Cognitive Impairment

Interventions

• BEHAVIORAL

No Results Yet

NCT03257033 | RECRUITING | PHASE3

190 participants

Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2018-03-12

Completion:

2027-06-30

Conditions

• Locally Advanced Pancreatic Cancer

Interventions

• DRUG
• DEVICE

No Results Yet

NCT03207945 | COMPLETED | PHASE3

118 participants

Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2018-04-30

Completion:

2025-08-24

Conditions

• Dyslipidemias
• Cardiovascular Diseases
• HIV Infections

Interventions

• DRUG
• OTHER

No Results Yet

NCT03190941 | RECRUITING | PHASE1/PHASE2

110 participants

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2017-09-21

Completion:

2027-06-29

Conditions

• Pancreatic Cancer
• Gastric Cancer
• Gastrointestinal Cancer
• Colon Cancer
• Rectal Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03185468 | TERMINATED | PHASE1/PHASE2

20 participants

Intervention of Bladder Cancer by CAR-T

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-08-01

Completion:

2026-07-01

Conditions

• Bladder Cancer
• Urothelial Carcinoma Bladder

Interventions

• GENETIC

No Results Yet

NCT03184753 | TERMINATED | PHASE1/PHASE2

100 participants

Genetically Modified T Cells Against Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-05-01

Completion:

2026-07-01

Conditions

• Ovarian Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03170141 | TERMINATED | PHASE1

30 participants

Immunogene-modified T (IgT) Cells Against Glioblastoma Multiforme

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2017-05-31

Completion:

2026-07-01

Conditions

• Glioblastoma Multiforme of Brain
• Brain Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03159364 | TERMINATED | PHASE1/PHASE2

100 participants

Antigen-specific Cytotoxic T Cells in the Treatment of Opportunistic Infections

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2026-06-01

Completion:

2026-07-01

Conditions

• Pathogen Infection
• EBV Infection
• CMV Infection
• Adenovirus Infection
• BKV Infection
• Fungus Infection
• Tuberculosis

Interventions

• BIOLOGICAL

No Results Yet

NCT03141177 | COMPLETED | PHASE3

701 participants

A Study of Nivolumab Combined With Cabozantinib Compared to Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2017-07-23

Completion:

2020-02-12

Conditions

• Renal Cell Carcinoma

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03125577 | TERMINATED | PHASE1/PHASE2

100 participants

Combination CAR-T Cell Therapy Targeting Hematological Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2025-08-01

Completion:

2026-07-01

Conditions

• B-cell Malignancies

Interventions

• BIOLOGICAL

No Results Yet

NCT03054519 | COMPLETED | PHASE3

202 participants

Improve PAD PERformance With METformin

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-24

Start Date:

2017-05-23

Completion:

2025-08-20

Conditions

• Peripheral Artery Disease

Interventions

• DRUG

Results Available