Clinical Trials

NCT05218421 | COMPLETED

70 participants

Carotid Artery Plaque Vulnerability Assessment Using Ultrafast Ultrasound Techniques

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2022-05-01

Completion:

2025-12-31

Conditions

• Carotid Artery Plaque

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT05215340 | ACTIVE_NOT_RECRUITING | PHASE3

740 participants

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-03-04

Completion:

2030-03-04

Conditions

• Metastatic Non Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05203627 | ACTIVE_NOT_RECRUITING | NA

53 participants

Telehealth for the Self-Management of Dietary Quality of Life in Patients After Stomach Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2020-01-21

Completion:

2026-10-01

Conditions

• Gastric Carcinoma
• Gastroesophageal Junction Adenocarcinoma

Interventions

• OTHER

No Results Yet

NCT05201131 | RECRUITING

50 participants

Canadian Cohort of Convective Thermal Therapy Using Rezūm System in Benign Prostatic Hyperplasia (BPH).

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2019-10-07

Completion:

2028-12-31

Conditions

• Urologic Diseases

Interventions

• PROCEDURE

No Results Yet

NCT05173961 | ACTIVE_NOT_RECRUITING | NA

20 participants

A Mobile Application, Oncpatient, to Assist Patients Undergoing Radiation Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-06-29

Completion:

2026-10-01

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT05169892 | RECRUITING

25 participants

Aquablation in Benign Prostatic Hyperplasia in Canada

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2019-10-09

Completion:

2029-12-31

Conditions

• Urologic Diseases

Interventions

• PROCEDURE

No Results Yet

NCT05155332 | SUSPENDED | PHASE1

190 participants

A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-03-28

Completion:

2027-12-13

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT05147792 | SUSPENDED | NA

1600 participants

The CONFORM Pivotal Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-05-26

Completion:

2028-06-30

Conditions

• Atrial Fibrillation
• Stroke

Interventions

• DEVICE

No Results Yet

NCT05145816 | RECRUITING | PHASE1/PHASE2

37 participants

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2024-02-15

Completion:

2027-03-01

Conditions

• AL Amyloidosis
• Amyloidosis

Interventions

• DRUG

No Results Yet

NCT05142696 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

55 participants

A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-07-13

Completion:

2028-03-07

Conditions

• Extensive Stage Small Cell Lung Cancer

Interventions

• DRUG
• OTHER

No Results Yet

NCT05123729 | RECRUITING

546 participants

Leveraging Social Innovation and Community-Engagement to Reduce Disparities in Outbreak Control Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2025-04-05

Completion:

2026-09-30

Conditions

• Outbreak Investigation

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05119569 | ACTIVE_NOT_RECRUITING | PHASE2

109 participants

A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-03-01

Completion:

2023-03-29

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

Results Available

NCT05111262 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

60 participants

Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily Maintenance Inhalers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-12-16

Completion:

2027-09-30

Conditions

• Asthma
• Nonadherence, Medication

Interventions

• DRUG

No Results Yet

NCT05110937 | RECRUITING

450 participants

Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2022-01-04

Completion:

2028-07-01

Conditions

• Sepsis
• Trauma Injury

Interventions

• OTHER

No Results Yet

NCT05100992 | RECRUITING

4000 participants

Progress Bifurcation Global Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2020-04-23

Completion:

2030-01-31

Conditions

• Coronary Artery Disease
• Coronary Bifurcation Lesions

Interventions

• PROCEDURE

No Results Yet

NCT05100940 | RECRUITING

4000 participants

Progress Complication

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2020-11-24

Completion:

2030-12-31

Conditions

• Coronary Artery Disease

Interventions

• PROCEDURE

No Results Yet

NCT05100862 | ACTIVE_NOT_RECRUITING | PHASE3

799 participants

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-03-10

Completion:

2028-07-31

Conditions

• Relapsed/Refractory Follicular Lymphoma
• Marginal Zone Lymphoma

Interventions

• DRUG

No Results Yet

NCT05082519 | RECRUITING | PHASE2

240 participants

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-03-12

Completion:

2027-08-15

Conditions

• B-cell Acute Lymphoblastic Leukemia
• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT05070390 | COMPLETED | PHASE1

18 participants

A Study of Enlicitide Chloride (MK-0616 Oral PCSK9 Inhibitor) in Participants With Moderate Renal Impairment (MK-0616-007)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-11-16

Completion:

2023-05-03

Conditions

• Moderate Renal Impairment

Interventions

• DRUG

Results Available

NCT05069038 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

Clinical Trial Assessing the Safety of Neoadjuvant Palbociclib in Combination With Endocrine Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-03-02

Completion:

2026-09-30

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05065073 | COMPLETED | PHASE4

62 participants

Iso-Osmolar vs. Low-Osmolar Contrast Agents for Optical Coherence Tomography

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-09-30

Completion:

2023-03-31

Conditions

• Coronary Artery Disease
• Contrast Media Reaction

Interventions

• DRUG

No Results Yet

NCT05046171 | COMPLETED | PHASE1/PHASE2

50 participants

Decreasing Polypharmacy in Older Adults With Curable Cancers Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-06-14

Completion:

2025-12-31

Conditions

• Cancer

Interventions

• OTHER

No Results Yet

NCT05036577 | COMPLETED | PHASE1

13 participants

A Dose-escalating Pilot Study of Orelabrutinib for Newly-diagnosed PCNSL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-10-10

Completion:

2023-12-31

Conditions

• Primary Central Nervous System Lymphoma

Interventions

• DRUG

No Results Yet

NCT05011422 | RECRUITING | PHASE1

50 participants

Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-11-03

Completion:

2029-05-31

Conditions

• Pediatric Hematologic Malignancies

Interventions

• DEVICE

No Results Yet

NCT04999969 | ACTIVE_NOT_RECRUITING | PHASE2

126 participants

Safety, Pharmacokinetics and Clinical Activity of AZD0171 in Combination With Durvalumab and Chemotherapy in Locally Advanced or Metastatic Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-12-10

Completion:

2024-10-07

Conditions

• Locally Advanced or Metastatic Solid Tumours

Interventions

• DRUG

Results Available

NCT04969471 | ACTIVE_NOT_RECRUITING | NA

148 participants

NATURE (EnVast as an Adjunct PPCI in Subjects Presenting With STEMI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-12-09

Completion:

2026-06-01

Conditions

• Segment Elevation Myocardial Infarction (STEMI)

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT04958239 | ACTIVE_NOT_RECRUITING | PHASE1

151 participants

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-10-18

Completion:

2026-04-27

Conditions

• Neoplasms

Interventions

• DRUG

No Results Yet

NCT04949464 | RECRUITING | NA

100 participants

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2023-03-22

Completion:

2026-12-31

Conditions

• HIV Infection
• Tobacco-Related Carcinoma

Interventions

• PROCEDURE
• BEHAVIORAL

No Results Yet

NCT04917328 | RECRUITING | NA

700 participants

Compression Ultrasonography in Non-high Probability of Deep Vein Thrombosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-02-21

Completion:

2027-02-28

Conditions

• Deep Vein Thrombosis

Interventions

• OTHER

No Results Yet

NCT04898790 | RECRUITING | NA

114 participants

Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-11-18

Completion:

2027-07-31

Conditions

• Leukemia
• Lymphoma
• Multiple Myeloma
• Myelodysplastic Syndromes (MDS)
• Myeloproliferative Neoplasm

Interventions

• BEHAVIORAL

No Results Yet

NCT04893109 | RECRUITING | PHASE2

500 participants

ATEMPT 2.0: Adjuvant T-DM1 vs TH

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-06-16

Completion:

2028-11-01

Conditions

• Breast Cancer
• HER2-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04874428 | RECRUITING | PHASE1

24 participants

Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-05-19

Completion:

2026-12-31

Conditions

• Liver Cirrhosis

Interventions

• DRUG

No Results Yet

NCT04873258 | RECRUITING

2000 participants

Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2019-09-27

Completion:

2027-12-31

Conditions

• Healthy
• Fatty Liver
• MASLD
• MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
• Obesity and Obesity-related Medical Conditions

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04847271 | COMPLETED | NA

42 participants

Physical Activity on Prescription for Children With Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2022-02-07

Completion:

2025-05-31

Conditions

• Obesity, Childhood

Interventions

• BEHAVIORAL

No Results Yet

NCT04832477 | COMPLETED | NA

500 participants

Assessing the PrEP Care Cascade Among Black Men and Transwomen in the Southeastern US

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-09-15

Completion:

2026-02-04

Conditions

• HIV Seropositivity
• Substance Use
• STI
• Stigma, Social

Interventions

• BEHAVIORAL

No Results Yet

NCT04827147 | COMPLETED | NA

64 participants

Clinical Trial of Multi-Periscopic Prism Glasses for Hemianopia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2023-04-03

Completion:

2025-04-30

Conditions

• Homonymous Hemianopia

Interventions

• DEVICE

Results Available

NCT04824989 | ACTIVE_NOT_RECRUITING | NA

305 participants

Parents Advancing Toddler Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-03-22

Completion:

2027-02-28

Conditions

• Sleep Problem
• Behavior, Child

Interventions

• BEHAVIORAL

No Results Yet

NCT04819997 | ACTIVE_NOT_RECRUITING | NA

42 participants

A Nurse-Led Intervention for Fear of Progression in Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-03-08

Completion:

2026-10-01

Conditions

• Advanced Lung Carcinoma
• Metastatic Malignant Female Reproductive System Neoplasm
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• OTHER

No Results Yet

NCT04803084 | SUSPENDED

10 participants

Multiparametric MRI as a Non-Invasive Biomarker of the Tumor Microenviroment

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-19

Start Date:

2021-08-09

Completion:

2026-08-31

Conditions

• Breast Cancer
• Triple-negative Breast Cancer

Interventions

• OTHER

No Results Yet

NCT04788095 | ACTIVE_NOT_RECRUITING | NA

21 participants

App-Based Mindfulness Intervention for the Improvement of Quality of Life in Patients With Metastatic Renal Cell Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-19

Start Date:

2021-08-23

Completion:

2026-10-01

Conditions

• Metastatic Renal Cell Carcinoma
• Stage IV Renal Cell Cancer AJCC v8

Interventions

• DEVICE
• OTHER

No Results Yet