Clinical Trials Updated in 2026

NCT04803084 | SUSPENDED

10 participants

Multiparametric MRI as a Non-Invasive Biomarker of the Tumor Microenviroment

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-08-09
Completion:: 2026-08-31

Conditions

Breast Cancer
Triple-negative Breast Cancer

Interventions

OTHER

No Results Yet

NCT04788095 | ACTIVE_NOT_RECRUITING | NA

21 participants

App-Based Mindfulness Intervention for the Improvement of Quality of Life in Patients With Metastatic Renal Cell Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-08-23
Completion:: 2026-10-01

Conditions

Metastatic Renal Cell Carcinoma
Stage IV Renal Cell Cancer AJCC v8

Interventions

DEVICE
OTHER

No Results Yet

NCT04775355 | RECRUITING

30 participants

Study to Detect Changes in Urinary and Gut Microbiome During Androgen Deprivation Therapy and Radiation Therapy in Patients With Prostate Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-04-14
Completion:: 2026-12-01

Conditions

Stage I Prostate Cancer AJCC v7
Stage II Prostate Cancer AJCC v7
Stage IIA Prostate Cancer AJCC v7
Stage IIB Prostate Cancer AJCC v7
Stage III Prostate Cancer AJCC v7
Stage IV Prostate Cancer AJCC v7

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04757883 | TERMINATED

37 participants

Immunological Follow-up After SARS CoV2 Vaccination in Kidney Transplant Recipients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-02-02
Completion:: 2024-11-01

Conditions

Kidney Transplant Recipients

Interventions

OTHER

No Results Yet

NCT04757220 | RECRUITING | NA

144 participants

Multidimensional Apathy in Psychiatric Pathologies.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2022-01-05
Completion:: 2027-03-01

Conditions

Apathy

Interventions

OTHER

No Results Yet

NCT04746859 | COMPLETED | NA

268 participants

Evaluation of the Effectiveness and Implementation of the BETTER Women Peer Health Coaching Program

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-06-14
Completion:: 2024-10-23

Conditions

Chronic Disease
Cancer

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT04725474 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

199 participants

First-in-Human Study of the GDF-15 Neutralizing Antibody Visugromab (CTL-002) in Patients With Advanced Cancer (GDFATHER)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-12-09
Completion:: 2028-04-30

Conditions

Solid Tumor, Adult

Interventions

BIOLOGICAL

No Results Yet

NCT04715568 | RECRUITING | PHASE4

100 participants

Secondhand Tobacco Smoke and Cardiovascular Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-03-30
Completion:: 2026-12-31

Conditions

Cardiovascular Diseases
Hypertension

Interventions

DRUG

No Results Yet

NCT04711369 | ACTIVE_NOT_RECRUITING | NA

92 participants

Lasertherapy for Vulvodynia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-01-15
Completion:: 2026-09-15

Conditions

Vulvodynia

Interventions

DEVICE

No Results Yet

NCT04707066 | COMPLETED | NA

253 participants

Comprehensive Adaptive Multisite Prevention of University Student Suicide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2022-10-25
Completion:: 2024-11-19

Conditions

Suicide

Interventions

BEHAVIORAL

Results Available

NCT04683250 | RECRUITING | PHASE1/PHASE2

244 participants

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-12-16
Completion:: 2030-03-31

Conditions

RET-altered Non Small Cell Lung Cancer
RET-altered Solid Tumors

Interventions

DRUG

No Results Yet

NCT04674969 | RECRUITING

5000 participants

Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-03-29
Completion:: 2028-01-31

Conditions

Peripheral Vascular Diseases

Interventions

DEVICE

No Results Yet

NCT04644068 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

702 participants

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-11-12
Completion:: 2027-05-28

Conditions

Ovarian Cancer
Breast Cancer
Pancreatic Cancer
Prostate Cancer
Additional Indications Below for Module 4 and 5
Non-small Cell Lung Cancer
Colorectal Cancer
Bladder Cancer
Gastric Cancer
Biliary Cancer
Cervical Cancer
Endometrial Cancer
Small Cell Lung Cancer Only in Module 5

Interventions

DRUG

No Results Yet

NCT04637282 | WITHDRAWN | PHASE3

0 participants

Safety, Tolerability, and Efficacy of PLX-200 in Patients With CLN3

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2026-11-01
Completion:: 2026-12-31

Conditions

Juvenile Neuronal Ceroid Lipofuscinosis

Interventions

DRUG

No Results Yet

NCT04597385 | ACTIVE_NOT_RECRUITING

27 participants

Long-term Follow-Up for RGX-121

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-03-14
Completion:: 2028-10-31

Conditions

Mucopolysaccharidosis II

Interventions

OTHER

No Results Yet

NCT04567771 | RECRUITING | NA

121 participants

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-12-04
Completion:: 2029-04-01

Conditions

Cervical Carcinoma
Endometrial Carcinoma
Endometriosis
Pelvic Inflammatory Disease

Interventions

OTHER
RADIATION

No Results Yet

NCT04567550 | ACTIVE_NOT_RECRUITING | PHASE2

139 participants

RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Diabetic Retinopathy (DR) With and Without Center Involved-Diabetic Macular Edema (CI-DME)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-11-20
Completion:: 2026-06-18

Conditions

Diabetic Retinopathy (DR)
Center-Involved Diabetic Macular Edema (CI-DME)

Interventions

GENETIC
DRUG
BIOLOGICAL

No Results Yet

NCT04566328 | RECRUITING | PHASE3

1450 participants

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-02-24
Completion:: 2027-12-31

Conditions

Plasma Cell Myeloma
RISS Stage I Plasma Cell Myeloma
RISS Stage II Plasma Cell Myeloma

Interventions

DRUG
BIOLOGICAL
OTHER

No Results Yet

NCT04550494 | ACTIVE_NOT_RECRUITING | PHASE2

29 participants

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-04-26
Completion:: 2026-07-10

Conditions

Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Castration-Resistant Prostate Carcinoma
Clinical Stage III Gastric Cancer AJCC v8
Clinical Stage IV Gastric Cancer AJCC v8
HER2-Positive Breast Carcinoma
Locally Advanced Breast Carcinoma
Locally Advanced Gastric Carcinoma
Locally Advanced Malignant Solid Neoplasm
Locally Advanced Ovarian Carcinoma
Locally Advanced Pancreatic Carcinoma
Locally Advanced Prostate Carcinoma
Metastatic Breast Carcinoma
Metastatic Gastric Carcinoma
Metastatic Malignant Solid Neoplasm
Metastatic Ovarian Carcinoma
Metastatic Pancreatic Carcinoma
Metastatic Prostate Carcinoma
Platinum-Sensitive Ovarian Carcinoma
Recurrent Breast Carcinoma
Recurrent Gastric Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Pancreatic Carcinoma
Recurrent Prostate Carcinoma
Stage II Pancreatic Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage III Pancreatic Cancer AJCC v8
Stage III Prostate Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8
Stage IV Prostate Cancer AJCC v8

Interventions

PROCEDURE
DRUG

No Results Yet

NCT04545736 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

55 participants

Oral Metformin for Treatment of ABCA4 Retinopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-11-23
Completion:: 2028-02-02

Conditions

ABCA4 Retinopathy
Stargardt Disease
Retinal Dystrophy
Retinal Degeneration

Interventions

DRUG

No Results Yet

NCT04517565 | ACTIVE_NOT_RECRUITING | NA

80 participants

Longitudinal Neuroimaging in Sturge-Weber Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-03-01
Completion:: 2026-02-28

Conditions

Sturge-Weber Syndrome

Interventions

DIAGNOSTIC_TEST
BEHAVIORAL

No Results Yet

NCT04506567 | ACTIVE_NOT_RECRUITING | PHASE1

60 participants

Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-08-18
Completion:: 2025-06-01

Conditions

Prostate Cancer

Interventions

DRUG
DIAGNOSTIC_TEST

Results Available

NCT04505436 | COMPLETED | PHASE2

215 participants

Study to Evaluate Efficacy, Safety and Tolerability of HM15211(Efocipegtrutide) in Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-07-31
Completion:: 2026-06-26

Conditions

NASH - Nonalcoholic Steatohepatitis

Interventions

DRUG

No Results Yet

NCT04505267 | ACTIVE_NOT_RECRUITING | PHASE1

34 participants

NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-02-10
Completion:: 2028-03-31

Conditions

Recurrent Lung Non-Small Cell Carcinoma
Stage I Lung Cancer AJCC v8
Stage IA1 Lung Cancer AJCC v8
Stage IA2 Lung Cancer AJCC v8
Stage IA3 Lung Cancer AJCC v8
Stage IB Lung Cancer AJCC v8
Stage II Lung Cancer AJCC v8
Stage IIA Lung Cancer AJCC v8
Stage IIB Lung Cancer AJCC v8
Stage III Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Unresectable Lung Non-Small Cell Carcinoma

Interventions

OTHER
RADIATION

No Results Yet

NCT04495244 | RECRUITING

10000 participants

A Study to Identify Breast Cancer (IDBC)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2019-01-24
Completion:: 2032-12-31

Conditions

Breast Cancer Female

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04482244 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

RCT of CBD for Anxiety in Advanced Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2022-01-19
Completion:: 2023-03-01

Conditions

Advanced Breast Cancer
Anxiety
CBD

Interventions

DRUG
OTHER

Results Available

NCT04433676 | RECRUITING

1500000 participants

Early PONV - a Registry Based Study in Sweden.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2016-01-01
Completion:: 2029-12-31

Conditions

Postoperative Nausea and Vomiting
Postoperative Complications

Interventions

OTHER

No Results Yet

NCT04430075 | ACTIVE_NOT_RECRUITING

1000 participants

MiCLASP Post Market Clinical Follow-Up (PMCF) Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2019-08-23
Completion:: 2025-09-04

Conditions

Mitral Regurgitation
Mitral Insufficiency

Interventions

DEVICE

No Results Yet

NCT04427566 | TERMINATED | PHASE2

2 participants

Low Dose Whole Lung Radiation Therapy for Patients With COVID-19 and Respiratory Compromise

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-07-23
Completion:: 2021-04-26

Conditions

COVID-19

Interventions

RADIATION

Results Available

NCT04423211 | RECRUITING | PHASE3

804 participants

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-10-08
Completion:: 2032-12-31

Conditions

Biochemically Recurrent Prostate Carcinoma
Metastatic Prostate Carcinoma
Prostate Adenocarcinoma
Stage IVB Prostate Cancer AJCC v8

Interventions

RADIATION
DRUG
PROCEDURE
OTHER

No Results Yet

NCT04411654 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

7 participants

Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-06-29
Completion:: 2027-02-28

Conditions

Gaucher Disease, Type 2

Interventions

GENETIC
DRUG

No Results Yet

NCT04406818 | ACTIVE_NOT_RECRUITING | NA

120 participants

Metabolic and Hemodynamic Reserve in Pediatric SCA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2021-06-30
Completion:: 2027-03-31

Conditions

Child, Only
Brain Diseases
Sickle Cell Disease
Anemia, Sickle Cell

Interventions

DRUG

No Results Yet

NCT04383275 | ACTIVE_NOT_RECRUITING | PHASE2

367 participants

Stage I HER2 Positive Invasive Breast Cancer De-escalation Study(IRIS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-05-20
Completion:: 2031-07-06

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT04375332 | ACTIVE_NOT_RECRUITING | NA

25 participants

Beating Heart Mitral Valve Repair With the HARPOON™ System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-12-16
Completion:: 2027-12-20

Conditions

Mitral Regurgitation

Interventions

DEVICE

No Results Yet

NCT04373317 | RECRUITING | PHASE4

358 participants

Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2022-10-24
Completion:: 2027-10-24

Conditions

Parkinson's Disease Psychosis

Interventions

DRUG

No Results Yet

NCT04370054 | ACTIVE_NOT_RECRUITING | PHASE3

77 participants

Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-08-18
Completion:: 2024-06-17

Conditions

Hemophilia A

Interventions

BIOLOGICAL

Results Available

NCT04339777 | RECRUITING | PHASE2

66 participants

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2020-09-22
Completion:: 2026-10-01

Conditions

Lymphoproliferative Disorders
Autoimmune Lymphoproliferative
Immune System Diseases
Common Variable Immunodeficiency
Primary T-cell Immunodeficiency Disorders

Interventions

DRUG
RADIATION
PROCEDURE

No Results Yet

NCT04179032 | ACTIVE_NOT_RECRUITING | PHASE2

25 participants

Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2019-11-28
Completion:: 2023-01-16

Conditions

Systemic Lupus Erythematosus

Interventions

COMBINATION_PRODUCT

Results Available

NCT04157049 | RECRUITING

5000 participants

Alpha-1 Research Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-19
Start Date:: 2019-06-20
Completion:: 2029-06-20

Conditions

Alpha 1-Antitrypsin Deficiency

No Results Yet

NCT04136054 | COMPLETED | NA

131 participants

Better Sleep in Psychiatric Care - Depression, Anxiety and PTSD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-19
Start Date:: 2019-09-25
Completion:: 2024-02-06

Conditions

Sleep Problem
Anxiety Disorders
Affective Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet