Clinical Trials

NCT04398628 | RECRUITING

3000 participants

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2020-09-30

Completion:

2035-06-30

Conditions

• Hematologic Disorder
• Bleeding Disorder
• Connective Tissue Disorder
• Hemophilia
• Thrombosis
• Von Willebrand Diseases
• Thrombophilia
• Rare Bleeding Disorder
• Platelet Disorder
• Factor IX Deficiency
• Factor VIII Deficiency
• Thalassemia
• Sickle Cell Disease

No Results Yet

NCT04396873 | RECRUITING | PHASE1

184 participants

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2021-08-17

Completion:

2029-04-11

Conditions

• Parkinson's Disease
• Dementia
• Alzheimer's Disease
• ALS
• Mild Cognitive Impairment

Interventions

• DRUG

No Results Yet

NCT04370704 | COMPLETED | PHASE1/PHASE2

61 participants

Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2020-07-27

Completion:

2025-08-25

Conditions

• Melanoma

Interventions

• DRUG

Results Available

NCT04364373 | RECRUITING | NA

1381 participants

D2 vs D3 Lymph Node Dissection for Left Colon Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2020-03-31

Completion:

2028-12-31

Conditions

• Colon Cancer

Interventions

• PROCEDURE

No Results Yet

NCT04333537 | RECRUITING | PHASE2/PHASE3

686 participants

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2020-09-23

Completion:

2031-04-27

Conditions

• Buccal Mucosa Squamous Cell Carcinoma
• Floor of Mouth Squamous Cell Carcinoma
• Gingival Squamous Cell Carcinoma
• Hard Palate Squamous Cell Carcinoma
• Lip Squamous Cell Carcinoma
• Lower Alveolar Ridge Squamous Cell Carcinoma
• Oral Cavity Squamous Cell Carcinoma
• Retromolar Trigone Squamous Cell Carcinoma
• Stage I Lip and Oral Cavity Cancer AJCC v8
• Stage II Lip and Oral Cavity Cancer AJCC v8
• Tongue Squamous Cell Carcinoma
• Upper Alveolar Ridge Squamous Cell Carcinoma

Interventions

• PROCEDURE
• OTHER
• DRUG

No Results Yet

NCT04332588 | RECRUITING | PHASE1

25 participants

Monitoring HER2+ Breast Cancer Neoadjuvant Treatment With Advanced PET/MRI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2022-03-25

Completion:

2027-08-31

Conditions

• HER2-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04321512 | RECRUITING

300 participants

Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2013-12-01

Completion:

2027-12-01

Conditions

• Myocardial Infarction
• Stroke, Ischemic
• Ischemia

Interventions

• OTHER

No Results Yet

NCT04318821 | COMPLETED | NA

30 participants

Effect of Laser Acupuncture on Adhesive Small Bowel Obstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2020-03-01

Completion:

2023-02-01

Conditions

• Adhesive Small Bowel Obstruction

Interventions

• PROCEDURE

No Results Yet

NCT04275726 | RECRUITING | NA

988 participants

LANDMARK Trial: a Randomised Controlled Trial of Myval THV

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2020-11-04

Completion:

2024-03-07

Conditions

• Aortic Valve Stenosis

Interventions

• DEVICE

No Results Yet

NCT04246684 | ACTIVE_NOT_RECRUITING | PHASE3

702 participants

Short RT Versus RCT,Followed by Chemo and Organ Preservation for Interm and High-risk Rectal Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2020-11-05

Completion:

2026-09-15

Conditions

• Rectal Cancer Stage III

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04220086 | COMPLETED | NA

78 participants

Pediatric Massage for Children With Autism Spectrum Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2021-05-30

Completion:

2022-06-30

Conditions

• Autism Spectrum Disorder

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04195568 | ACTIVE_NOT_RECRUITING | NA

248 participants

Evaluation of Safety and Effectiveness of Stryker Surpass Evolve™ Flow Diverter System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2020-07-07

Completion:

2025-07-14

Conditions

• Aneurysm, Intracranial

Interventions

• DEVICE

No Results Yet

NCT04158258 | COMPLETED

2907 participants

A Study to Describe the Diagnosis, Anti-Cancer Treatment and Clinical Outcome in Patients With Newly Diagnosed Breast Cancer in Latin America

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2020-02-21

Completion:

2026-07-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04154423 | COMPLETED | NA

678 participants

Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2019-11-07

Completion:

2024-12-23

Conditions

• Premature Birth
• Pregnancy Preterm
• Prenatal Stress
• Depression, Anxiety
• Depression, Postpartum
• Satisfaction, Patient
• Health Problems in Pregnancy

Interventions

• OTHER

Results Available

NCT04134260 | ACTIVE_NOT_RECRUITING | PHASE3

586 participants

Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2020-04-16

Completion:

2026-11-01

Conditions

• Prostate Adenocarcinoma
• Stage I Prostate Cancer AJCC v8
• Stage II Prostate Cancer AJCC v8
• Stage III Prostate Cancer AJCC v8
• Stage IVA Prostate Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• OTHER
• RADIATION

No Results Yet

NCT04039633 | ACTIVE_NOT_RECRUITING | NA

6 participants

Spinal Cord Stimulation for Refractory Pain in Erythromelalgia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2019-08-26

Completion:

2024-04-23

Conditions

• Erythromelalgia

Interventions

• PROCEDURE

No Results Yet

NCT04030273 | COMPLETED

62 participants

Prevalence of Intrauterine Adhesions After Myomectomy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2020-01-21

Completion:

2021-03-29

Conditions

• Myoma;Uterus

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04009226 | COMPLETED

430 participants

International GNE Myopathy Patient Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2014-03-31

Completion:

2021-12-31

Conditions

• GNE Myopathy
• Hereditary Inclusion Body Myopathy

Interventions

• OTHER

No Results Yet

NCT03980054 | ACTIVE_NOT_RECRUITING | PHASE3

2135 participants

A Study of Evaluating The Effects Of Pyrotinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2019-07-12

Completion:

2027-06-30

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT03965468 | ACTIVE_NOT_RECRUITING | PHASE2

96 participants

Immunotherapy, Chemotherapy, Radiotherapy and Surgery for Synchronous Oligo-metastatic NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2019-11-19

Completion:

2026-08-31

Conditions

• Non-small Cell Lung Cancer
• Stage IV
• Oligometastasis

Interventions

• DRUG
• RADIATION
• PROCEDURE

No Results Yet

NCT03950778 | COMPLETED | EARLY_PHASE1

40 participants

The Effect of Albumin Supplementation on the Inflammatory and Oxidative Stress Markers in Septic Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2023-03-04

Completion:

2024-03-11

Conditions

• Albumin Supplementation
• Albumin Therapy
• Sepsis

Interventions

• DRUG

No Results Yet

NCT03943901 | ACTIVE_NOT_RECRUITING | PHASE2

27 participants

Split-Dose R-CHOP for Older Adults With DLBCL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2021-02-17

Completion:

2025-01-13

Conditions

• Diffuse Large B Cell Lymphoma
• DLBCL
• Cancer

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT03825250 | TERMINATED | PHASE1/PHASE2

45 participants

The Val-CARD Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2018-11-06

Completion:

2023-11-03

Conditions

• Cardiac Valve Disease
• Coronary Artery Disease
• Organ Failure, Multiple

Interventions

• DRUG

No Results Yet

NCT03784924 | RECRUITING

950 participants

EDRN Prostate MRI Biomarker Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2019-02-04

Completion:

2028-06-30

Conditions

• PSA
• Prostate Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03740126 | COMPLETED | NA

750 participants

Surveillance With PET/CT and Liquid Biopsies of Stage I-III Lung Cancer Patients After Completion of Definitive Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2018-10-25

Completion:

2023-09-01

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03698071 | COMPLETED | NA

48 participants

Soluble CD95 Ligand Role in the Pathophysiology of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2018-12-14

Completion:

2024-09-18

Conditions

• ANCA Associated Vasculitis

Interventions

• BIOLOGICAL

No Results Yet

NCT03685721 | RECRUITING

800 participants

Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2018-10-11

Completion:

2027-07-01

Conditions

• Sickle Cell
• PKLR Variants
• Adenosine Triphosphate Activities

No Results Yet

NCT03681678 | COMPLETED

100 participants

Laser Therapy for Treatment of Urogenital Symptoms in Women

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2018-10-08

Completion:

2022-12-15

Conditions

• Genitourinary System; Disorder, Female
• Burning Vagina
• Dyspareunia
• Irritation; Vagina
• Menopause Related Conditions
• Urinary Incontinence
• Urinary Bladder, Overactive
• Urinary Tract Infections
• Stress Urinary Incontinence

Interventions

• DEVICE

Results Available

NCT03656172 | COMPLETED

51 participants

Interest of Reticulocyte Haemoglobin Content (RET-he) in Management of Functional Anemia for Patient With Solid Tumor

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2017-05-04

Completion:

2020-05-11

Conditions

• Solid Tumor, Adult
• Anemia Deficiency

Interventions

• BIOLOGICAL

Results Available

NCT03654833 | COMPLETED | PHASE2

186 participants

Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2019-01-28

Completion:

2023-02-21

Conditions

• Mesothelioma, Malignant

Interventions

• DRUG

Results Available

NCT03650764 | COMPLETED | PHASE1/PHASE2

43 participants

Ramucirumab + Pembrolizumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2019-05-29

Completion:

2026-05-11

Conditions

• Head and Neck Squamous Cell Carcinoma

Interventions

• DRUG

Results Available

NCT03646617 | ACTIVE_NOT_RECRUITING | PHASE2

62 participants

Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2018-11-27

Completion:

2026-03-21

Conditions

• Metastatic Melanoma

Interventions

• RADIATION
• DRUG

No Results Yet

NCT03626844 | RECRUITING | NA

100 participants

Maternal Outcomes Following Manual Lysis of the Placenta.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2026-07-20

Completion:

2027-07-31

Conditions

• Third Stage of Delivery

Interventions

• PROCEDURE

No Results Yet

NCT03519464 | ACTIVE_NOT_RECRUITING | PHASE2

54 participants

Immunogenicity of the 9-Valent Human Papillomavirus Recombinant Vaccine in People With Idiopathic CD4 T Cell Lymphocytopenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2019-02-04

Completion:

2026-12-31

Conditions

• Idiopathic CD4 T Cell Lymphocytopenia

Interventions

• BIOLOGICAL

No Results Yet

NCT03469609 | RECRUITING | NA

120 participants

Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds ("MUC-FIRE" Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2018-06-18

Completion:

2027-12-31

Conditions

• Enterostomy

Interventions

• OTHER

No Results Yet

NCT03463408 | COMPLETED | EARLY_PHASE1

14 participants

Immunotherapy + Radiation in Resectable Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2018-07-17

Completion:

2024-08-19

Conditions

• Sarcoma

Interventions

• DRUG

No Results Yet

NCT03392324 | COMPLETED | NA

5 participants

PRIMA US-Feasibility Study in Atrophic Dry AMD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2018-04-26

Completion:

2026-05-20

Conditions

• Dry Age-related Macular Degeneration

Interventions

• DEVICE

No Results Yet

NCT03331380 | RECRUITING | NA

2950 participants

Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2018-01-05

Completion:

2028-05-31

Conditions

• CAD

Interventions

• DEVICE

No Results Yet

NCT03314324 | COMPLETED | PHASE2

250 participants

A Study of Patient Preference Between ODM-201 and Enzalutamide in Men With Metastatic Castrate-resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-17

Start Date:

2017-11-29

Completion:

2022-01-31

Conditions

• Metastatic Castrate-resistant Prostate (CRPC) Cancer

Interventions

• DRUG

No Results Yet

NCT03253692 | COMPLETED

66 participants

Prospective Multicenter Registry On Radiation Dose Estimates Of Cardiac CT Angiography in Daily Practice in 2017 (PROTECTION VI)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-17

Start Date:

2017-10-03

Completion:

2018-06-30

Conditions

• Coronary Artery Disease
• Coronary Disease
• Myocardial Ischemia
• Arterial Occlusive Diseases
• Arteriosclerosis

No Results Yet