Clinical Trials

NCT07743463 | RECRUITING | PHASE3

3003 participants

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-31
Completion:: 2028-07-31

Conditions

Obesity
Overweight
Chronic Weight Management

Interventions

DRUG

No Results Yet

NCT07743450 | RECRUITING | PHASE3

1560 participants

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-31
Completion:: 2028-07-31

Conditions

Obesity
Overweight
Chronic Weight Management
Type 2 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT07743099 | COMPLETED

46 participants

Renal and Cerebral NIRS and Early Acute Kidney Injury in Cooled Neonates With Birth Asphyxia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2021-01-01
Completion:: 2021-06-30

Conditions

Hypoxic-Ischemic Encephalopathy
Acute Kidney Injury
Hypoxic-Ischemic Encephalopathy, Neonatal
Asphyxia Neonatorum

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07742189 | RECRUITING | NA

30 participants

Medication Collaboration Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-03
Completion:: 2026-12-31

Conditions

Dementia Family Caregiver
Dementia
Medication Adherence

Interventions

BEHAVIORAL

No Results Yet

NCT07737951 | RECRUITING | NA

40 participants

Tai Chi for Reducing Aromatase Inhibitor-Induced Arthralgia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-07-27
Completion:: 2027-06-30

Conditions

Hormone Receptor Positive Breast Carcinoma
Postmenopausal
Breast Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT07737925 | NOT_YET_RECRUITING | PHASE2

30 participants

LuX: Xaluritamig in Participants With Metastatic Castrate Resistant Prostate Cancer and Suboptimal Response to Lutetium 177 Vipivotide Tetraxetan

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-10-31
Completion:: 2030-10-31

Conditions

Prostate Cancer
Metastatic Castrate Resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT07735728 | NOT_YET_RECRUITING | PHASE1

32 participants

A First-in-Human Study of ZE66-0205 in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-15
Completion:: 2027-08-15

Conditions

Healthy Volunteers (HV)

Interventions

DRUG

No Results Yet

NCT07733908 | NOT_YET_RECRUITING | PHASE2

22 participants

Effectiveness of Posluma PET Scan for Post-Treatment Monitoring of Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-31
Completion:: 2030-07-31

Conditions

Prostate Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07726602 | RECRUITING

100 participants

Tumor-informed ctDNA in Muscle-invasive Bladder Cancer for Evaluation of Residual/Recurrent Disease - the TiMBER Trial

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-06-29
Completion:: 2027-01-31

Conditions

Muscle Invasive Bladder Urothelial Carcinoma
Stage II Bladder Cancer AJCC v8
Stage IIIA Bladder Cancer AJCC v8

Interventions

OTHER

No Results Yet

NCT07722741 | NOT_YET_RECRUITING | PHASE2

90 participants

Personalized Neoantigen Vaccine Plus IL-12 (INO-9012) Versus Active Surveillance in Subjects With High-Risk HCC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-09-30
Completion:: 2029-09-30

Conditions

HCC

Interventions

BIOLOGICAL
DEVICE

No Results Yet

NCT07721558 | NOT_YET_RECRUITING | NA

100 participants

Effect of Inspired Oxygen Concentration on Postoperative Atelectasis After VATS Lobectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-09-01
Completion:: 2027-12-01

Conditions

Atelectasis
Postoperative Pulmonary Complications

Interventions

PROCEDURE

No Results Yet

NCT07715903 | NOT_YET_RECRUITING | PHASE1

20 participants

Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2029-12-31

Conditions

Colorectal Neoplasms
Neoplasms
Intrahepatic Cholangiocarcinoma
Adrenocortical Carcinoma
Metastasis, Neoplasm

Interventions

DRUG

No Results Yet

NCT07715890 | NOT_YET_RECRUITING | NA

48 participants

Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic Hyperlipidemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2028-11-30

Conditions

Lipid Metabolism Disorders

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07714954 | NOT_YET_RECRUITING | NA

140 participants

Replication: Meaning-centered Intervention for Internalizing Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-10-31
Completion:: 2028-02-29

Conditions

Depression and/or Anxiety Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT07714278 | ENROLLING_BY_INVITATION | NA

150 participants

Effectiveness of Video-Based Movement Analysis-Guided Personalized Rehabilitation in Patients With Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-06-30
Completion:: 2028-05-31

Conditions

Chemotherapy-induced Peripheral Neuropathy (CIPN)

Interventions

BEHAVIORAL

No Results Yet

NCT07712874 | NOT_YET_RECRUITING

10000 participants

Screening Protocol

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2050-07-02

Conditions

Pain

No Results Yet

NCT07712107 | RECRUITING | NA

10000 participants

A Study on Gastrointestinal Cancer Screening Using a Multi-Targeted Combined Detection Model

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-06-15
Completion:: 2035-12-31

Conditions

Gastrointestinal Tumors

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07708727 | RECRUITING | PHASE2/PHASE3

700 participants

Study of an Injectable Regimen of GS-3242 With Lenacapavir Compared to Biktarvy in People New to HIV-1 Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-07-29
Completion:: 2030-10-31

Conditions

HIV-1-infection

Interventions

DRUG

No Results Yet

NCT07706374 | RECRUITING | PHASE1

40 participants

E.N.D.E.A.V.O.R.: An Exemestane Needed Dose Efficacy and Verification as an Ovulation Induction Regimen Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-31
Completion:: 2028-12-31

Conditions

Poly Cystic Ovary Syndrome

Interventions

DRUG

No Results Yet

NCT07703475 | NOT_YET_RECRUITING | PHASE1

80 participants

A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-15
Completion:: 2027-11-15

Conditions

COVID -19

Interventions

BIOLOGICAL

No Results Yet

NCT07702032 | RECRUITING | PHASE3

960 participants

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer (LiGeR-CRC1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-11
Completion:: 2029-07-31

Conditions

Left-sided Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT07701733 | RECRUITING

500 participants

A Study of Lung Cancer Risk

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-06-30
Completion:: 2029-06-30

Conditions

Lung Cancer

Interventions

OTHER

No Results Yet

NCT07700212 | NOT_YET_RECRUITING | PHASE1

10 participants

A Phase 1 Trial Of Safety And Initial Efficacy Of Vagal Nerve Blockade For Cancer-Induced Cachexia In Patients With Metastatic Pancreatic Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-09-30
Completion:: 2026-12-30

Conditions

Metastatic Pancreatic Adenocarcinoma

Interventions

DEVICE

No Results Yet

NCT07699991 | RECRUITING | NA

330 participants

A Navigation Program to Improve Survivorship Support Service Participation Among Non-metastatic Breast Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-09-01
Completion:: 2027-12-31

Conditions

Anatomic Stage 0 Breast Cancer AJCC v8
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Localized Breast Carcinoma

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT07696052 | ACTIVE_NOT_RECRUITING | NA

62 participants

Phosphatidylserine, Taurine, and Caffeine for Cognitive Fatigue in Professional Football Players

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-06
Completion:: 2026-08-10

Conditions

Mental Fatigue
Cognitive Performance
Athletic Performance
Soccer Performance
Decision Making

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07693751 | NOT_YET_RECRUITING | PHASE1/PHASE2

100 participants

A Study Testing SOT109 for the First Time in Patients, to Assess How Safe SOT109 is, How Well it Works, and How the Body Handles it in Patients With Advanced Colorectal Cancer That Can Not be Removed by Surgery or is Metastatic

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-29
Completion:: 2027-11-29

Conditions

Colorectal Cancer (Locally Advanced or Metastatic)

Interventions

BIOLOGICAL

No Results Yet

NCT07692594 | NOT_YET_RECRUITING

32 participants

Heart and Blood Vessels Health in People With Cystic Fibrosis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-09-01
Completion:: 2028-08-30

Conditions

Cystic Fibrosis (CF)
Cardiovascular (CV) Risk
Flow-mediated Dilation Evaluation of the Brachial Artery
Pulse Wave Analysis

No Results Yet

NCT07686393 | RECRUITING | PHASE1

40 participants

PET Imaging of Noradrenergic Transmission in the Brain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2029-02-05

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT07686380 | NOT_YET_RECRUITING | PHASE2

65 participants

IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2029-01-30

Conditions

Recurrent Prostate Cancer
Prostate Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT07683104 | RECRUITING

750 participants

Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2056-05-01

Conditions

Trisomy 8 Mosaicism
Trisomy 8 Associated Autoinflammatory Disease
Mucosal Ulcerations

No Results Yet

NCT07683065 | RECRUITING

150 participants

A Study to Estimate Secukinumab Retention Rate in Psoriasis Patients With MASLD

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-07-08
Completion:: 2027-01-15

Conditions

Plaque Psoriasis
Metabolic Dysfunction-Associated Steatotic Liver Disease

No Results Yet

NCT07682961 | RECRUITING | PHASE3

590 participants

Study of Lenacapavir, Teropavimab, and Zinlirvimab Versus Cabotegravir and Rilpivirine in Virologically Suppressed Adults With HIV-1 on Oral Daily Antiretroviral Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-07-14
Completion:: 2029-03-31

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT07682909 | NOT_YET_RECRUITING

1020 participants

oneKNEE - Prospective, Non-interventional, Multicenter PMCF-Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2027-04-30
Completion:: 2030-04-30

Conditions

Arthroplasty
Arthroplasty Replacement, Knee
Prosthetic Joint Infections of Knee
TKA Outcomes

Interventions

DEVICE

No Results Yet

NCT07681713 | NOT_YET_RECRUITING | PHASE3

120 participants

Long-Term Efficacy Study of Vatiquinone for the Treatment of Friedreich's Ataxia (FA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-15
Completion:: 2029-03-15

Conditions

Friedreich's Ataxia

Interventions

DRUG

No Results Yet

NCT07678242 | NOT_YET_RECRUITING | NA

1500 participants

The Lucida Project

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-10-31
Completion:: 2028-10-31

Conditions

Depression Disorder

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT07673341 | NOT_YET_RECRUITING | PHASE2

22 participants

[18F]FTT Positron Emission Tomography/Computed Tomography to Predict Treatment Response in Patients Scheduled to Receive Gemcitabine, Cisplatin, and Durvalumab for Newly Diagnosed Cholangiocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-11-01
Completion:: 2028-07-01

Conditions

Cholangiocarcinoma

Interventions

PROCEDURE
RADIATION

No Results Yet

NCT07672483 | NOT_YET_RECRUITING | PHASE1

95 participants

IL-12 Genetically Engineered Myeloid Cells in Participants With Relapsed, Refractory Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2028-01-15

Conditions

Relapsed Solid Tumor Malignancies
Refractory Solid Tumor Malignancies

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07668817 | RECRUITING | NA

92 participants

Tract Closure in PCNL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-31
Completion:: 2028-05-31

Conditions

Nephrolithiasis

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT07667400 | NOT_YET_RECRUITING | PHASE1/PHASE2

120 participants

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2036-10-01

Conditions

Head and Neck Cancer
Head and Neck Squamous Cell Carcinoma
Paranasal Sinus Neoplasms
Nasopharyngeal Carcinoma
Oropharyngeal Squamous Cell Carcinoma
Hypopharyngeal Cancer
Carcinoma of Larynx
Oral Squamous Cell Carcinoma
Salivary Gland Cancer
Adenoid Cystic Carcinoma
Prostate Cancer
Metastatic Castration Resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT07662928 | NOT_YET_RECRUITING | PHASE2

43 participants

Epcoritamab in Combination With Dose Adjusted EPOCH-R for High-risk Burkitt Lymphoma (BL), The BEDROCK Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-09-17
Completion:: 2031-05-30

Conditions

Adult Burkitt Lymphoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet