Clinical Trials

NCT07067151 | ENROLLING_BY_INVITATION

30 participants

Using Smartwatches to Monitor Smoking in Real-life Situations

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2027-04-30

Conditions

Smoking

No Results Yet

NCT07062536 | RECRUITING | PHASE2

130 participants

mFOLFOX/mFOLFIRI vs. mFOLFOX in Advanced or Recurrent Biliary Tract Cancer Second-line

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-08-27
Completion:: 2027-04-01

Conditions

Biliary Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT07061977 | RECRUITING | PHASE3

336 participants

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-11-05
Completion:: 2030-12-31

Conditions

Locally Advanced Cervical Adenocarcinoma
Locally Advanced Cervical Adenosquamous Carcinoma
Locally Advanced Cervical Squamous Cell Carcinoma
Stage IIIA Cervical Cancer FIGO 2018
Stage IIIB Cervical Cancer FIGO 2018
Stage IIIC1 Cervical Cancer FIGO 2018
Stage IIIC2 Cervical Cancer FIGO 2018
Stage IVA Cervical Cancer FIGO 2018

Interventions

PROCEDURE
RADIATION
DRUG
BIOLOGICAL

No Results Yet

NCT07060807 | RECRUITING | PHASE3

1000 participants

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-21
Completion:: 2033-07-14

Conditions

Breast Neoplasms

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07056946 | COMPLETED | NA

70 participants

Supra Inguinal Fascia Iliaca Block Versus Ultrasound-guided Caudal Analgesia for Pediatrics Undergoing Anterior and Lateral Thigh Surgeries: A Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-08-01
Completion:: 2026-08-01

Conditions

Cancer Bone

Interventions

OTHER

No Results Yet

NCT07054515 | RECRUITING | PHASE3

147 participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-06-30
Completion:: 2028-05-14

Conditions

Niemann-Pick Type C Disease
GM1 Gangliosidosis
GM2 Gangliosidosis

Interventions

DRUG

No Results Yet

NCT07053020 | NOT_YET_RECRUITING | PHASE1/PHASE2

58 participants

A Phase 1b/2 Open-label, Dose-ranging Safety and Efficacy Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2027-12-01
Completion:: 2028-06-30

Conditions

Acute Myeloid Leukemia (AML)

Interventions

DRUG

No Results Yet

NCT07052903 | RECRUITING | PHASE3

1750 participants

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-02
Completion:: 2030-05-28

Conditions

Transthyretin Amyloidosis With Cardiomyopathy

Interventions

DRUG

No Results Yet

NCT07044687 | RECRUITING | PHASE4

100 participants

Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-24
Completion:: 2027-11-30

Conditions

Acute Myeloid Leukemia

Interventions

DRUG

No Results Yet

NCT07044297 | RECRUITING | PHASE3

4390 participants

A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-31
Completion:: 2027-07-22

Conditions

Human Immunodeficiency Virus (HIV)
HIV Pre-Exposure Prophylaxis

Interventions

DRUG

No Results Yet

NCT07040319 | RECRUITING | PHASE1/PHASE2

30 participants

Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-06-25
Completion:: 2028-03-03

Conditions

Hepatitis C

Interventions

DRUG

No Results Yet

NCT07036835 | ACTIVE_NOT_RECRUITING | NA

128 participants

Clinical Investigation of a Femtosecond Laser for Corneal Flap Creation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-08-27
Completion:: 2026-08-31

Conditions

Refractive Errors

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT07036536 | RECRUITING

1000 participants

Non-Euploid Embryo Transfer (NEET) Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-09-23
Completion:: 2030-12-31

Conditions

Infertility
Mosaicism
Aneuploidy

No Results Yet

NCT07034287 | ACTIVE_NOT_RECRUITING | NA

40 participants

Modifying the Geriatric Acute & Post-acute Care Coordination Program for Fall Prevention in the Emergency Department for Telehealth

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-01-13
Completion:: 2026-08-31

Conditions

Older Adults (65 Years and Older)
Fall Prevention
Telehealth
Emergency Department

Interventions

OTHER

No Results Yet

NCT07033494 | RECRUITING | PHASE2

340 participants

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-16
Completion:: 2029-04-30

Conditions

Early Alzheimer's Disease

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07028853 | RECRUITING | PHASE3

1000 participants

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-09-28
Completion:: 2028-09-12

Conditions

Metastatic Castration Sensitive Prostate Cancer (mCSPC)
Hormone Sensitive Prostate Cancer
Prostate Cancer
Cancer of the Prostate

Interventions

DRUG

No Results Yet

NCT07027826 | RECRUITING | NA

70 participants

The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2027-08-31

Conditions

Dysphagia
Eosinophilic Esophagitis

Interventions

DEVICE

No Results Yet

NCT07013474 | RECRUITING | PHASE3

300 participants

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-14
Completion:: 2027-09-27

Conditions

COVID-19 Infection

Interventions

DRUG

No Results Yet

NCT07007559 | RECRUITING | PHASE2

120 participants

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-12-10
Completion:: 2027-12-31

Conditions

Breast Cancer, Metastatic

Interventions

DRUG

No Results Yet

NCT07007065 | RECRUITING | PHASE3

561 participants

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-11-05
Completion:: 2033-03-31

Conditions

Neovascular Age-related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT07005297 | NOT_YET_RECRUITING

1000 participants

Clinical Genetics Branch Eligibility Screening Survey

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2035-01-01

Conditions

Melanoma
Li-Fraumeni Syndrome
Pulmonary Blastoma
Chordoma
Congenital Bone Marrow Failure Syndromes
Costello Syndrome
Fanconi Anemia
CFC Syndrome (CFCS)
Legius Syndrome
RASopathies

No Results Yet

NCT06995898 | RECRUITING | NA

24000 participants

The Vanguard Study: Testing a New Way to Screen for Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-06-18
Completion:: 2029-01-31

Conditions

Bladder Carcinoma
Breast Carcinoma
Colorectal Carcinoma
Esophageal Carcinoma
Gastric Carcinoma
Liver Carcinoma
Lung Carcinoma
Malignant Solid Neoplasm
Ovarian Carcinoma
Pancreatic Carcinoma
Prostate Carcinoma

Interventions

PROCEDURE
DEVICE
OTHER

No Results Yet

NCT06995885 | ENROLLING_BY_INVITATION

30 participants

Development of an Interview-Informed Timeline Follow-Back (TLFB) for Opioid Use in the Era of Fentanyl

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2027-05-31

Conditions

Substance Use Disorders (SUDs)

No Results Yet

NCT06991751 | NOT_YET_RECRUITING

50 participants

A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2026-08-31

Conditions

Cardiometabolic Risk Factors
Mental Health

No Results Yet

NCT06991738 | NOT_YET_RECRUITING | PHASE1/PHASE2

18 participants

177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2032-07-01

Conditions

Thyroid Cancer

Interventions

DIAGNOSTIC_TEST
OTHER
DRUG

No Results Yet

NCT06990997 | RECRUITING | NA

160 participants

Effects of Aphasia Identification Cards on Service Workers' Comprehension of People With Aphasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-09-22
Completion:: 2027-02-28

Conditions

Aphasia

Interventions

BEHAVIORAL

No Results Yet

NCT06984354 | RECRUITING | NA

720 participants

Digitally Delivered Treatments to Reduce Chronic Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-06-02
Completion:: 2027-05-26

Conditions

Low Back Pain
Chronic Pain (Back / Neck)
General Practice (GP), Primary Care Settings
Digital Health
Hypnosis, Chronic Pain Management
Patient Education

Interventions

BEHAVIORAL

No Results Yet

NCT06982209 | COMPLETED | NA

125 participants

ANI-Guided Anesthetic Desflurane Consumption

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-07-02
Completion:: 2026-07-12

Conditions

Postoperative Pain
General Anesthesia
Laparoscopic Cholecystectomy

Interventions

DEVICE

No Results Yet

NCT06981221 | COMPLETED

50 participants

PVI Predictors in Laparoscopic Hysterectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-07-01
Completion:: 2026-07-10

Conditions

Hysterectomy
PVI
Fluid Responsiveness

Interventions

DEVICE

No Results Yet

NCT06976697 | RECRUITING | NA

200 participants

Home-Based tDCS Treatment Of Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-06-27
Completion:: 2026-10-10

Conditions

Major Depressive Disorder (MDD)

Interventions

DEVICE

No Results Yet

NCT06976086 | ACTIVE_NOT_RECRUITING | NA

50 participants

Pediatric Expansion Study of the Sentio System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-04-30
Completion:: 2026-10-01

Conditions

Hearing Loss, Conductive
Hearing Loss, Mixed
Single Sided Deafness

Interventions

DEVICE

No Results Yet

NCT06975306 | RECRUITING | NA

75 participants

Radiographic Findings and Clinical Outcomes After Bone Grafting Patellar Defect in ACL Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-02-11
Completion:: 2027-04-30

Conditions

Bone Graft; Complications
ACL Injuries

Interventions

PROCEDURE
OTHER

No Results Yet

NCT06970496 | NOT_YET_RECRUITING | PHASE1

48 participants

A Clinical Trial of B019 Injection in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-31
Completion:: 2026-12-31

Conditions

Relapsed or Refractory B Cell Non Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT06966700 | RECRUITING | PHASE3

2400 participants

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-06-30
Completion:: 2033-03-23

Conditions

Breast Neoplasms
Triple Negative Breast Neoplasms
HR Low-Positive/HER2-Negative Breast Neoplasms

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06963827 | RECRUITING | PHASE3

347 participants

A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-15
Completion:: 2028-09-07

Conditions

Kidney Disease

Interventions

DRUG

No Results Yet

NCT06963671 | ENROLLING_BY_INVITATION | NA

90 participants

Blood Flow Restriction for Ulnar Sided Wrist Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-08-11
Completion:: 2028-12-31

Conditions

Ulnar Wrist Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06948318 | RECRUITING | PHASE3

150 participants

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-08-14
Completion:: 2029-07-29

Conditions

Immune Thrombocytopenic Purpura (ITP)

Interventions

DRUG

No Results Yet

NCT06948110 | RECRUITING

300 participants

Deciphering the Genetic Architecture of Autoimmune Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2030-04-22

Conditions

Autoimmune Diseases

No Results Yet

NCT06948097 | RECRUITING | PHASE1

30 participants

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2028-07-14

Conditions

Lung Transplantation

Interventions

DRUG

No Results Yet

NCT06940752 | ENROLLING_BY_INVITATION | NA

30 participants

VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) Catheters

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2026-12-01

Conditions

Ventricular Arrhythmia

Interventions

DEVICE

No Results Yet