Clinical Trials

NCT06806033 | RECRUITING | PHASE2

100 participants

A Study to Evaluate the Optimization of the Cytokine Release Syndrome Profile for Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed/Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-03-05
Completion:: 2027-01-31

Conditions

B-Cell Non-Hodgkins Lymphoma

Interventions

DRUG

No Results Yet

NCT06800248 | NOT_YET_RECRUITING | PHASE3

315 participants

Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-11-06
Completion:: 2027-06-30

Conditions

Trichuris Trichiura; Infection
Hookworm Infection
Ascaris Lumbricoides Infection

Interventions

DRUG

No Results Yet

NCT06797193 | RECRUITING | NA

60 participants

Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-03-13
Completion:: 2027-03-31

Conditions

Portal Hypertension

Interventions

OTHER
PROCEDURE
DRUG

No Results Yet

NCT06796075 | ACTIVE_NOT_RECRUITING | NA

8 participants

Identifying Strategies to Reduce Cardiovascular Risk Among Mothers of Young Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-28
Completion:: 2026-12-31

Conditions

Cardiovascular Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT06772623 | RECRUITING | PHASE1/PHASE2

252 participants

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-03-06
Completion:: 2027-11-30

Conditions

Non Small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT06750978 | COMPLETED | NA

47 participants

Interventions for PSU Among College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-12-18
Completion:: 2026-07-30

Conditions

Problematic Smartphone Use

Interventions

BEHAVIORAL

No Results Yet

NCT06749457 | RECRUITING | PHASE1/PHASE2

231 participants

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-12-30
Completion:: 2027-04-02

Conditions

Staphylococcus Aureus

Interventions

DRUG
OTHER

No Results Yet

NCT06745921 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-02-24
Completion:: 2026-10-01

Conditions

West Nile Viral Infection

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT06744283 | RECRUITING

20 participants

Experience and Management of Cancer Screening-Related Anxiety in Fanconi Anemia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2026-09-01

Conditions

Fanconi Anemia

No Results Yet

NCT06743555 | NOT_YET_RECRUITING | PHASE1

14 participants

Surgery After Verifying Existing Disease in Locally Advanced Operable Lung Cancer: A Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-10-01
Completion:: 2027-02-28

Conditions

Non-Small Cell Lung Cancer
Immunotherapy
Neoadjuvant Therapy
Thoracic Surgery
Complete Response

Interventions

OTHER
PROCEDURE

No Results Yet

NCT06738303 | RECRUITING | PHASE2

44 participants

Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-14
Completion:: 2026-12-31

Conditions

Metastatic Prostate Cancer
Metastatic Castration-resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06736691 | ACTIVE_NOT_RECRUITING | PHASE3

315 participants

Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-11-25
Completion:: 2026-07-01

Conditions

Trichuris Trichiura; Infection
Hookworm Infection
Ascaris Lumbricoides Infection

Interventions

DRUG

No Results Yet

NCT06731166 | COMPLETED | NA

140 participants

Effectiveness of Video Monitoring and Care Transition for Heart Failure Patients (EVIT-HF): Randomized Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-12-01
Completion:: 2026-03-01

Conditions

Heart Failure With Reduced Ejection Fraction (HFrEF)

Interventions

BEHAVIORAL

No Results Yet

NCT06719609 | SUSPENDED | NA

30 participants

Enovis High Ankle Sprain Brace Testing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-10-31
Completion:: 2027-05-31

Conditions

Athletes in Cutting Sports

Interventions

OTHER

No Results Yet

NCT06719310 | COMPLETED | PHASE1/PHASE2

36 participants

Phase Ib/IIa Clinical Study of ACC017 Tablets

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-08-28
Completion:: 2025-04-28

Conditions

Infection, Human Immunodeficiency Virus

Interventions

DRUG

No Results Yet

NCT06718101 | ACTIVE_NOT_RECRUITING | PHASE2

83 participants

A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-12-19
Completion:: 2027-05-31

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06717711 | RECRUITING | PHASE3

158 participants

Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Robot-assisted Surgical Treatment of Genitourinary Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-09-15
Completion:: 2027-02-28

Conditions

Prostate Carcinoma
Erectile Function
Genito Urinary Cancer

Interventions

DEVICE
DRUG

No Results Yet

NCT06717347 | RECRUITING | PHASE3

1046 participants

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-01-27
Completion:: 2029-07-02

Conditions

Diffuse Large B-Cell Lymphoma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06713837 | RECRUITING | PHASE3

339 participants

IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-02-27
Completion:: 2028-01-31

Conditions

Acute Myeloid Leukemia
Relapse/Recurrence

Interventions

DRUG

No Results Yet

NCT06708182 | COMPLETED | NA

53 participants

SAGE LEAF 2: An Online Program to Reduce Dementia Caregiver Burden

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-07-02
Completion:: 2026-07-01

Conditions

Caregiving Stress
Caregiver Burden

Interventions

BEHAVIORAL

No Results Yet

NCT06705348 | RECRUITING

100 participants

Social Disconnection Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-05-08
Completion:: 2028-02-29

Conditions

Social Disconnection

No Results Yet

NCT06701617 | RECRUITING | NA

200 participants

In-person and Telehealth Visual Rehabilitation for Children With Low Vision

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-11-25
Completion:: 2027-05-31

Conditions

Visual Rehabilitation
Oddball Design
Cerebral Visual Impairment
Passive Visual Stimulation
Perceptual Learning

Interventions

BEHAVIORAL

No Results Yet

NCT06699849 | RECRUITING | PHASE2

70 participants

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-08-07
Completion:: 2027-10-22

Conditions

Sickle Cell Disease Vaso-occlusive Crisis

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06696755 | RECRUITING | PHASE2

195 participants

A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-02-03
Completion:: 2027-11-30

Conditions

Bipolar I Disorder
Bipolar II Disorder

Interventions

DRUG

No Results Yet

NCT06694454 | SUSPENDED | PHASE1/PHASE2

60 participants

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2031-12-31

Conditions

Non-small Cell Lung Cancer (NSCLC)
Carcinoma, Non-Small Cell Lung
Non-Small Cell Lung Carcinoma
Non Small Cell Lung Cancer
Non Small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT06693778 | ACTIVE_NOT_RECRUITING

3000 participants

Utilizing Electronic Clinical Decision Support to Enhance mTBI Care at the Primary Care Point of Entry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2023-04-01
Completion:: 2027-03-31

Conditions

Brain Concussion
Mild Traumatic Brain Injury

Interventions

OTHER

No Results Yet

NCT06690294 | NOT_YET_RECRUITING

110 participants

Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2027-01-30

Conditions

Healthy Volunteer
Obestity

No Results Yet

NCT06685848 | ACTIVE_NOT_RECRUITING | NA

24 participants

Comparison of Hemanext ONE® System and Conventional Red Blood Cell Transfusion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-11-29
Completion:: 2028-05-31

Conditions

Hematologic Neoplasms

Interventions

DEVICE

No Results Yet

NCT06681896 | RECRUITING | NA

40 participants

Microvascular Coronary Rehabilitation For Improving Treatment - Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-11-12
Completion:: 2027-04-01

Conditions

Microvascular Coronary Dysfunction
Microvascular Angina
Coronary Microvascular Dysfunction (CMD)

Interventions

OTHER

No Results Yet

NCT06680232 | RECRUITING | PHASE1

45 participants

Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-11-14
Completion:: 2026-12-31

Conditions

HEPATITIS B CHRONIC

Interventions

BIOLOGICAL

No Results Yet

NCT06679621 | RECRUITING | NA

357 participants

A Telehealth Intervention to Increase Patient Preparedness for Surgery in Latinas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-11-01
Completion:: 2027-06-01

Conditions

Incontinence
Prolapse

Interventions

BEHAVIORAL

No Results Yet

NCT06679140 | RECRUITING | PHASE3

2330 participants

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-12-08
Completion:: 2027-10-03

Conditions

COVID-19 SARS-CoV-2 Infection

Interventions

DRUG

No Results Yet

NCT06676059 | RECRUITING

10000 participants

SMART-r: Substance Monitoring and Active Relapse Tracking Repository

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2044-12-31

Conditions

Alcoholism
Substance-Related Disorders

No Results Yet

NCT06671847 | COMPLETED | NA

11 participants

Feasibility of At-Home Chair-Based Resistance Band Training to Improve Balance, Strength, and Bone Density in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-03-05
Completion:: 2026-01-07

Conditions

Sarcopenic Obesity

Interventions

DEVICE

No Results Yet

NCT06669156 | COMPLETED

21 participants

Insufficient Regional Anesthesia and Conversion to General Anesthesia for Cesarean Section A Qualitative Multicenter Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-02-01
Completion:: 2025-08-31

Conditions

Cesarean Section Complications
Cesarean Section Pain
Regional Anesthesia

No Results Yet

NCT06668584 | RECRUITING | PHASE2

31 participants

A Phase II Open-label Study of Olutasidenib Post-transplant Maintenance Therapy for Patients With IDH1-mutated Myeloid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-12-31
Completion:: 2027-12-31

Conditions

Myeloid Malignancies

Interventions

DRUG

No Results Yet

NCT06667700 | RECRUITING | PHASE3

3082 participants

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2024-12-02
Completion:: 2031-01-26

Conditions

Coronavirus Disease (COVID-19)

Interventions

DRUG

No Results Yet

NCT06667687 | ACTIVE_NOT_RECRUITING | PHASE1

21 participants

Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-01-16
Completion:: 2027-04-30

Conditions

Non-Hodgkin's Lymphoma

Interventions

DRUG

No Results Yet

NCT06664814 | RECRUITING | PHASE2

30 participants

An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Primary Focal Segmental Glomerulosclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2026-08-19
Completion:: 2027-11-30

Conditions

Focal Segmental Glomerulosclerosis

Interventions

DRUG

No Results Yet

NCT06659549 | RECRUITING | PHASE2

110 participants

A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-14
Start Date:: 2025-01-10
Completion:: 2027-03-30

Conditions

Geographic Atrophy of the Macula

Interventions

DRUG

No Results Yet