Clinical Trials

NCT04940507 | ACTIVE_NOT_RECRUITING | NA

50 participants

BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-06-10

Completion:

2026-12-31

Conditions

• Brain Neoplasms
• Liquid Biopsy

Interventions

• PROCEDURE

No Results Yet

NCT04924101 | COMPLETED | PHASE2

122 participants

Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-07-15

Completion:

2025-06-23

Conditions

• Small Cell Lung Cancer

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04912739 | RECRUITING

18000 participants

Targeted Health Dialogues in Primary Care

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2020-10-01

Completion:

2030-12-31

Conditions

• Health Behaviors
• Risk Factors
• Cardiovascular Diseases
• Cancer
• Serious Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT04910269 | TERMINATED | PHASE3

741 participants

Outpatient Treatment With Anti-Coronavirus Immunoglobulin

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-08-06

Completion:

2026-05-24

Conditions

• COVID
• SARS-CoV2 Infection
• Covid19

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04853342 | RECRUITING | PHASE3

318 participants

To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-06-07

Completion:

2026-12-31

Conditions

• Non-small Cell Lung Carcinoma

Interventions

• DRUG

No Results Yet

NCT04828096 | ACTIVE_NOT_RECRUITING | NA

324 participants

Retention With Three Different Bonded Retainers a Multicenter, Randomized Controlled Trial With 5-year Follow-up

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-25

Completion:

2030-09-30

Conditions

• Dental Malocclusion
• Stability

Interventions

• OTHER

No Results Yet

NCT04820400 | COMPLETED | NA

82 participants

Reducing Pain and Anxiety During Dressing Changes After Burn Surgery Using Virtual Reality

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-24

Completion:

2025-02-12

Conditions

• Pain, Postoperative
• Trauma
• Burns

Interventions

• OTHER

No Results Yet

NCT04802395 | RECRUITING

10000 participants

Real World Evidence Clinical Utility Study of KidneyIntelX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-02

Completion:

2026-12-01

Conditions

• Chronic Kidney Diseases
• Diabetic Kidney Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04796493 | ACTIVE_NOT_RECRUITING

98 participants

Objective Grading of MTS With LSCI and Thermography

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-16

Completion:

2023-06-30

Conditions

• Mesenteric Traction Syndrome

No Results Yet

NCT04791358 | ACTIVE_NOT_RECRUITING

1500 participants

Decision Impact Trial of KidneyIntelX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-01

Completion:

2026-11-01

Conditions

• Diabetic Kidney Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04780568 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-01-18

Completion:

2026-12-31

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04772131 | ACTIVE_NOT_RECRUITING | NA

300 participants

Desara ® One Single Incision Sling 522 Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-01

Completion:

2026-08-07

Conditions

• Stress Urinary Incontinence

Interventions

• DEVICE

No Results Yet

NCT04746703 | COMPLETED | NA

25 participants

New Imaging Tools to Explore Impact of Bariatric Surgery on Pancreatic Lesions: PACHIBA- Bariatric Surg

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-02-10

Completion:

2023-09-16

Conditions

• Bariatric Surgery

Interventions

• RADIATION

No Results Yet

NCT04725019 | WITHDRAWN | NA

0 participants

Enhancing Motor Learning in Children With Cerebral Palsy Using Transcranial Direct-current Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2023-03-01

Completion:

2026-07-31

Conditions

• Cerebral Palsy

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04708431 | RECRUITING

650 participants

Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-04-29

Completion:

2040-02-01

Conditions

• Androgen Insensitivity Syndrome
• Metabolic Parameters in AIS, CAIS, PAIS and MAIS
• Tumor Formation in AIS, CAIS, PAIS and MAIS
• Sexual Function AIS, CAIS, PAIS and MAIS

No Results Yet

NCT04664192 | ACTIVE_NOT_RECRUITING

100 participants

Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-06-04

Completion:

2026-12-01

Conditions

• Respiratory Failure
• Interstitial Lung Disease
• Lung Diseases

Interventions

• OTHER

No Results Yet

NCT04646473 | COMPLETED | NA

300 participants

Sweetgoals for Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-07-25

Completion:

2025-04-30

Conditions

• Type 1 Diabetes

Interventions

• BEHAVIORAL

Results Available

NCT04645147 | COMPLETED | PHASE1

83 participants

Safety and Immunogenicity of an Epstein-Barr Virus (EBV) gp350-Ferritin Nanoparticle Vaccine in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-03-29

Completion:

2025-07-01

Conditions

• EBV
• Epstein-Barr Virus Infection
• Infectious Mononucleosis

Interventions

• BIOLOGICAL

Results Available

NCT04640896 | COMPLETED | PHASE4

60 participants

Trigger Point Injections in Anterior Cervical Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-05

Completion:

2023-10-31

Conditions

• Myofacial Pain
• Pain, Neck
• Pain, Back
• Cervical Fusion

Interventions

• DRUG

Results Available

NCT04628871 | TERMINATED

13 participants

Long Term Follow-up (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-03

Completion:

2026-06-17

Conditions

• Hemophilia B
• Mucopolysaccharidosis I
• Mucopolysaccharidosis II

Interventions

• BIOLOGICAL

No Results Yet

NCT04617639 | ENROLLING_BY_INVITATION | NA

9700 participants

The Norwegian Trial of Physical Exercise After Myocardial Infarction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-09-29

Completion:

2028-07-31

Conditions

• Myocardial Infarction

Interventions

• BEHAVIORAL

No Results Yet

NCT04603807 | ACTIVE_NOT_RECRUITING | PHASE3

217 participants

A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-09-30

Completion:

2026-09-30

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT04586010 | ACTIVE_NOT_RECRUITING | PHASE3

746 participants

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-17

Completion:

2026-01-27

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT04569032 | COMPLETED | PHASE2

82 participants

A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-12

Completion:

2024-05-09

Conditions

• Peripheral T-cell Lymphoma

Interventions

• DRUG

Results Available

NCT04522336 | COMPLETED | PHASE1

16 participants

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-09-16

Completion:

2026-08-07

Conditions

• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Localized Gastroesophageal Junction Adenocarcinoma
• Locally Advanced Gastroesophageal Junction Adenocarcinoma
• Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Unresectable Gastroesophageal Junction Adenocarcinoma

Interventions

• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT04499079 | COMPLETED | NA

7316 participants

Alliances to Disseminate Addiction Prevention and Treatment (ADAPT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-06-01

Completion:

2025-11-30

Conditions

• Substance-Related Disorders
• Recidivism
• Opioid-Related Disorders
• Substance Use
• Criminal Behavior

Interventions

• OTHER

No Results Yet

NCT04462770 | RECRUITING | PHASE3

150 participants

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-09-15

Completion:

2027-04-30

Conditions

• Dravet Syndrome

Interventions

• DRUG

No Results Yet

NCT04451590 | COMPLETED | NA

40 participants

Virtual Reality: a Teaching-learning Strategy for Cognitive Mastery in Airway Trauma Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-08-01

Completion:

2022-12-15

Conditions

• Education, Medical
• Airway Management
• Students, Medical
• Virtual Reality
• Trauma Centers
• Manikins

Interventions

• OTHER

No Results Yet

NCT04448327 | COMPLETED | NA

62 participants

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-01-29

Completion:

2025-06-13

Conditions

• Major Depressive Disorder

Interventions

• DEVICE

Results Available

NCT04447027 | COMPLETED | PHASE1

26 participants

Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-12-17

Completion:

2024-07-01

Conditions

• Cutaneous T-Cell Lymphoma
• Mature T-cell Malignancies
• Peripheral T-Cell Lymphoma
• Relapsed/ Refractory T-cell Malignancies

Interventions

• DRUG
• DIAGNOSTIC_TEST
• PROCEDURE

Results Available

NCT04367649 | COMPLETED | NA

155 participants

Evaluation of Hall Technique and Atraumatic Restorative Treatment for Management of Caries in the Primary Dentition

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-11-20

Completion:

2019-11-29

Conditions

• Primary Dental Caries

Interventions

• OTHER

No Results Yet

NCT04343716 | COMPLETED | NA

19 participants

Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-10-01

Completion:

2023-09-18

Conditions

• Knee Osteoarthritis

Interventions

• BEHAVIORAL

Results Available

NCT04291196 | COMPLETED | NA

66 participants

Virtual Reality to Reduce Pre-procedure Anxiety Prior ECT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-27

Completion:

2024-09-03

Conditions

• ECT
• Electroconvulsive Therapy
• Virtual Reality
• Anxiety
• Education
• Hemodynamics
• Depression
• Cognition
• Mental Health

Interventions

• OTHER

No Results Yet

NCT04220073 | COMPLETED | PHASE1

40 participants

Phase I Study of Comparing Single Dose JS005 (Recombinant Humanized Monoclonal Antibody Against IL-17A) With Placebo in Tolerability, Safety, Immunogenicity and Pharmacokinetic in Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-05-17

Completion:

2020-11-20

Conditions

• Tolerability, Safety, Immunogenicity and Pharmacokinetic of JS005

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04190563 | COMPLETED | NA

83 participants

Pain, Inflammation and Opioid Craving

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-05-04

Completion:

2025-07-31

Conditions

• Opioid-use Disorder

Interventions

• BEHAVIORAL

Results Available

NCT04170153 | ACTIVE_NOT_RECRUITING | PHASE1

161 participants

Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-12-20

Completion:

2026-11-30

Conditions

• Metastatic or Locally Advanced Unresectable Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04113018 | ACTIVE_NOT_RECRUITING | PHASE2

39 participants

Study of Daratumumab Combined With Carfilzomib, Lenalidomide and Dexamethasone for Newly Diagnosed Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-01-10

Completion:

2023-06-28

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT04094701 | RECRUITING | NA

170 participants

Hip Arthroscopy Postoperative Opioid Demands

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-10-21

Completion:

2027-11-30

Conditions

• Opioid Use
• Pain
• Femoral Acetabular Impingement
• Labral Tear, Glenoid

Interventions

• OTHER

No Results Yet

NCT04083456 | COMPLETED | NA

35 participants

Dysvascular Amputation Self-Management of Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-11-01

Completion:

2025-05-31

Conditions

• Amputation
• Diabetes Mellitus
• Peripheral Artery Disease

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT04082429 | ACTIVE_NOT_RECRUITING | PHASE3

156 participants

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-11-13

Completion:

2022-07-12

Conditions

• Haemophilia A Without Inhibitors
• Haemophilia B Without Inhibitors

Interventions

• DRUG

Results Available