Clinical Trials

NCT04888936 | RECRUITING

500 participants

Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2022-04-25

Completion:

2031-01-31

Conditions

• Costello Syndrome
• Noonan Syndrome
• Cardiofaciocutaneous Syndrome
• Legius Syndrome
• Capillary Arteriovenous Malformation Syndrome
• RASopathy

No Results Yet

NCT04853342 | RECRUITING | PHASE3

318 participants

To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-06-07

Completion:

2026-12-31

Conditions

• Non-small Cell Lung Carcinoma

Interventions

• DRUG

No Results Yet

NCT04828096 | ACTIVE_NOT_RECRUITING | NA

324 participants

Retention With Three Different Bonded Retainers a Multicenter, Randomized Controlled Trial With 5-year Follow-up

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-25

Completion:

2030-09-30

Conditions

• Dental Malocclusion
• Stability

Interventions

• OTHER

No Results Yet

NCT04820400 | COMPLETED | NA

82 participants

Reducing Pain and Anxiety During Dressing Changes After Burn Surgery Using Virtual Reality

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-24

Completion:

2025-02-12

Conditions

• Pain, Postoperative
• Trauma
• Burns

Interventions

• OTHER

No Results Yet

NCT04802395 | RECRUITING

10000 participants

Real World Evidence Clinical Utility Study of KidneyIntelX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-02

Completion:

2026-12-01

Conditions

• Chronic Kidney Diseases
• Diabetic Kidney Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04796493 | ACTIVE_NOT_RECRUITING

98 participants

Objective Grading of MTS With LSCI and Thermography

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-16

Completion:

2023-06-30

Conditions

• Mesenteric Traction Syndrome

No Results Yet

NCT04791358 | ACTIVE_NOT_RECRUITING

1500 participants

Decision Impact Trial of KidneyIntelX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-01

Completion:

2026-11-01

Conditions

• Diabetic Kidney Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04780568 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-01-18

Completion:

2026-12-31

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04772131 | ACTIVE_NOT_RECRUITING | NA

300 participants

Desara ® One Single Incision Sling 522 Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-01

Completion:

2026-08-07

Conditions

• Stress Urinary Incontinence

Interventions

• DEVICE

No Results Yet

NCT04755205 | RECRUITING

525 participants

A Natural History Study of Children and Adults With Olfactory Neuroblastoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2022-06-02

Completion:

2029-12-31

Conditions

• Olfactory Neuroblastoma
• Esthesioneuroblastoma

No Results Yet

NCT04746703 | COMPLETED | NA

25 participants

New Imaging Tools to Explore Impact of Bariatric Surgery on Pancreatic Lesions: PACHIBA- Bariatric Surg

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-02-10

Completion:

2023-09-16

Conditions

• Bariatric Surgery

Interventions

• RADIATION

No Results Yet

NCT04725019 | WITHDRAWN | NA

0 participants

Enhancing Motor Learning in Children With Cerebral Palsy Using Transcranial Direct-current Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2023-03-01

Completion:

2026-07-31

Conditions

• Cerebral Palsy

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04708431 | RECRUITING

650 participants

Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-04-29

Completion:

2040-02-01

Conditions

• Androgen Insensitivity Syndrome
• Metabolic Parameters in AIS, CAIS, PAIS and MAIS
• Tumor Formation in AIS, CAIS, PAIS and MAIS
• Sexual Function AIS, CAIS, PAIS and MAIS

No Results Yet

NCT04692675 | RECRUITING | NA

508 participants

Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-11-18

Completion:

2029-09-01

Conditions

• Prostate Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04665739 | RECRUITING | PHASE2

70 participants

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2023-02-03

Completion:

2027-07-01

Conditions

• Advanced Lung Neuroendocrine Tumor
• Functioning Lung Neuroendocrine Tumor
• Locally Advanced Lung Neuroendocrine Neoplasm
• Lung Neuroendocrine Neoplasm
• Lung Neuroendocrine Tumor G1
• Lung Neuroendocrine Tumor G2
• Metastatic Lung Neuroendocrine Neoplasm
• Metastatic Lung Neuroendocrine Tumor
• Non-Functioning Lung Neuroendocrine Tumor
• Recurrent Lung Neuroendocrine Neoplasm
• Unresectable Lung Neuroendocrine Neoplasm
• Unresectable Lung Neuroendocrine Tumor

Interventions

• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT04664192 | ACTIVE_NOT_RECRUITING

100 participants

Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-06-04

Completion:

2026-12-01

Conditions

• Respiratory Failure
• Interstitial Lung Disease
• Lung Diseases

Interventions

• OTHER

No Results Yet

NCT04646473 | COMPLETED | NA

300 participants

Sweetgoals for Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-07-25

Completion:

2025-04-30

Conditions

• Type 1 Diabetes

Interventions

• BEHAVIORAL

Results Available

NCT04645160 | RECRUITING | PHASE1/PHASE2

31 participants

Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-03-04

Completion:

2028-12-31

Conditions

• Cholangiocarcinoma
• Bile Duct Neoplasm
• Biliary Tract Malignancy

Interventions

• DRUG

No Results Yet

NCT04645147 | COMPLETED | PHASE1

83 participants

Safety and Immunogenicity of an Epstein-Barr Virus (EBV) gp350-Ferritin Nanoparticle Vaccine in Healthy Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-03-29

Completion:

2025-07-01

Conditions

• EBV
• Epstein-Barr Virus Infection
• Infectious Mononucleosis

Interventions

• BIOLOGICAL

Results Available

NCT04640896 | COMPLETED | PHASE4

60 participants

Trigger Point Injections in Anterior Cervical Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-05

Completion:

2023-10-31

Conditions

• Myofacial Pain
• Pain, Neck
• Pain, Back
• Cervical Fusion

Interventions

• DRUG

Results Available

NCT04628871 | TERMINATED

13 participants

Long Term Follow-up (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-03

Completion:

2026-06-17

Conditions

• Hemophilia B
• Mucopolysaccharidosis I
• Mucopolysaccharidosis II

Interventions

• BIOLOGICAL

No Results Yet

NCT04617639 | ENROLLING_BY_INVITATION | NA

9700 participants

The Norwegian Trial of Physical Exercise After Myocardial Infarction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-09-29

Completion:

2028-07-31

Conditions

• Myocardial Infarction

Interventions

• BEHAVIORAL

No Results Yet

NCT04603807 | ACTIVE_NOT_RECRUITING | PHASE3

217 participants

A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-09-30

Completion:

2026-09-30

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT04586010 | ACTIVE_NOT_RECRUITING | PHASE3

746 participants

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-17

Completion:

2026-01-27

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT04569032 | COMPLETED | PHASE2

82 participants

A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-12

Completion:

2024-05-09

Conditions

• Peripheral T-cell Lymphoma

Interventions

• DRUG

Results Available

NCT04557969 | RECRUITING

400 participants

Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2020-12-18

Completion:

2040-12-30

Conditions

• Gastric Cancer
• Gastric Neoplasm
• Gastrointestinal Stromal Sarcoma
• Gastrointestinal Stromal Neoplasm
• Gastrointestinal Stromal Tumor (GIST)

No Results Yet

NCT04522336 | COMPLETED | PHASE1

16 participants

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-09-16

Completion:

2026-08-07

Conditions

• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Localized Gastroesophageal Junction Adenocarcinoma
• Locally Advanced Gastroesophageal Junction Adenocarcinoma
• Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Unresectable Gastroesophageal Junction Adenocarcinoma

Interventions

• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT04499079 | COMPLETED | NA

7316 participants

Alliances to Disseminate Addiction Prevention and Treatment (ADAPT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-06-01

Completion:

2025-11-30

Conditions

• Substance-Related Disorders
• Recidivism
• Opioid-Related Disorders
• Substance Use
• Criminal Behavior

Interventions

• OTHER

No Results Yet

NCT04465214 | COMPLETED

49 participants

Mobile Sensor Technologies to Assess General Symptomology of People With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-23

Completion:

2024-04-10

Conditions

• Neoplasms
• Solid Tumors
• Prostate Cancer
• Lung Cancer
• Colon Cancer

No Results Yet

NCT04462770 | RECRUITING | PHASE3

150 participants

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-09-15

Completion:

2027-04-30

Conditions

• Dravet Syndrome

Interventions

• DRUG

No Results Yet

NCT04451590 | COMPLETED | NA

40 participants

Virtual Reality: a Teaching-learning Strategy for Cognitive Mastery in Airway Trauma Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-08-01

Completion:

2022-12-15

Conditions

• Education, Medical
• Airway Management
• Students, Medical
• Virtual Reality
• Trauma Centers
• Manikins

Interventions

• OTHER

No Results Yet

NCT04448327 | COMPLETED | NA

62 participants

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-01-29

Completion:

2025-06-13

Conditions

• Major Depressive Disorder

Interventions

• DEVICE

Results Available

NCT04447027 | COMPLETED | PHASE1

26 participants

Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-12-17

Completion:

2024-07-01

Conditions

• Cutaneous T-Cell Lymphoma
• Mature T-cell Malignancies
• Peripheral T-Cell Lymphoma
• Relapsed/ Refractory T-cell Malignancies

Interventions

• DRUG
• DIAGNOSTIC_TEST
• PROCEDURE

Results Available

NCT04431024 | RECRUITING

300 participants

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-03-30

Completion:

2038-06-30

Conditions

• Familial Cancer
• BRCA1-Associated Protein-1 (BAP1) Mutations
• Tumor Predisposition Syndrome (TPDS)
• Mesothelioma

No Results Yet

NCT04411147 | ACTIVE_NOT_RECRUITING

583 participants

A Longitudinal Study of COVID-19 Sequelae and Immunity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2020-06-17

Completion:

2027-12-31

Conditions

• COVID-19

No Results Yet

NCT04367649 | COMPLETED | NA

155 participants

Evaluation of Hall Technique and Atraumatic Restorative Treatment for Management of Caries in the Primary Dentition

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-11-20

Completion:

2019-11-29

Conditions

• Primary Dental Caries

Interventions

• OTHER

No Results Yet

NCT04349475 | ACTIVE_NOT_RECRUITING | NA

40 participants

Therapeutic Omegas for Triglyceride Suppression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-11-29

Completion:

2026-04-30

Conditions

• Pregnancy

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04343716 | COMPLETED | NA

19 participants

Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-10-01

Completion:

2023-09-18

Conditions

• Knee Osteoarthritis

Interventions

• BEHAVIORAL

Results Available

NCT04305041 | COMPLETED | PHASE1/PHASE2

100 participants

Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-06-26

Completion:

2025-08-25

Conditions

• Melanoma

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04291196 | COMPLETED | NA

66 participants

Virtual Reality to Reduce Pre-procedure Anxiety Prior ECT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-11-27

Completion:

2024-09-03

Conditions

• ECT
• Electroconvulsive Therapy
• Virtual Reality
• Anxiety
• Education
• Hemodynamics
• Depression
• Cognition
• Mental Health

Interventions

• OTHER

No Results Yet