Clinical Trials

NCT04220073 | COMPLETED | PHASE1

40 participants

Phase I Study of Comparing Single Dose JS005 (Recombinant Humanized Monoclonal Antibody Against IL-17A) With Placebo in Tolerability, Safety, Immunogenicity and Pharmacokinetic in Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-05-17

Completion:

2020-11-20

Conditions

• Tolerability, Safety, Immunogenicity and Pharmacokinetic of JS005

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04202393 | COMPLETED | NA

178 participants

Intervention for Comorbid Substance Use and Bipolar Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-10-21

Completion:

2025-08-31

Conditions

• Bipolar Disorder
• Substance Use Disorders

Interventions

• BEHAVIORAL

Results Available

NCT04190563 | COMPLETED | NA

83 participants

Pain, Inflammation and Opioid Craving

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2021-05-04

Completion:

2025-07-31

Conditions

• Opioid-use Disorder

Interventions

• BEHAVIORAL

Results Available

NCT04181060 | RECRUITING | PHASE3

300 participants

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-12-28

Completion:

2026-12-31

Conditions

• Advanced Lung Non-Squamous Non-Small Cell Carcinoma
• Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
• Recurrent Lung Non-Squamous Non-Small Cell Carcinoma
• Stage IIIB Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT04170153 | ACTIVE_NOT_RECRUITING | PHASE1

161 participants

Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-12-20

Completion:

2026-11-30

Conditions

• Metastatic or Locally Advanced Unresectable Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04166409 | RECRUITING | PHASE3

170 participants

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-01-31

Completion:

2030-12-31

Conditions

• Low Grade Astrocytoma
• Low Grade Glioma
• Metastatic Low Grade Astrocytoma
• Metastatic Low Grade Glioma
• WHO Grade 1 Glioma
• WHO Grade 2 Glioma

Interventions

• PROCEDURE
• DRUG
• OTHER

No Results Yet

NCT04113018 | ACTIVE_NOT_RECRUITING | PHASE2

39 participants

Study of Daratumumab Combined With Carfilzomib, Lenalidomide and Dexamethasone for Newly Diagnosed Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-01-10

Completion:

2023-06-28

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT04094701 | RECRUITING | NA

170 participants

Hip Arthroscopy Postoperative Opioid Demands

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-10-21

Completion:

2027-11-30

Conditions

• Opioid Use
• Pain
• Femoral Acetabular Impingement
• Labral Tear, Glenoid

Interventions

• OTHER

No Results Yet

NCT04086485 | RECRUITING | PHASE1/PHASE2

56 participants

Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2022-10-03

Completion:

2027-07-01

Conditions

• Gastroenteropancreatico Tumors
• Neuroendocrine Tumors
• Neuroendocrine Neoplasms

Interventions

• DRUG
• DIAGNOSTIC_TEST

No Results Yet

NCT04083456 | COMPLETED | NA

35 participants

Dysvascular Amputation Self-Management of Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-11-01

Completion:

2025-05-31

Conditions

• Amputation
• Diabetes Mellitus
• Peripheral Artery Disease

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT04082429 | ACTIVE_NOT_RECRUITING | PHASE3

156 participants

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-11-13

Completion:

2022-07-12

Conditions

• Haemophilia A Without Inhibitors
• Haemophilia B Without Inhibitors

Interventions

• DRUG

Results Available

NCT04036409 | COMPLETED | NA

4368 participants

Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Stroke Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-08-05

Completion:

2026-07-08

Conditions

• Ischemic Stroke
• Blood Pressure
• Cognitive Impairment
• Vascular Diseases

Interventions

• DRUG

No Results Yet

NCT04014348 | RECRUITING

250 participants

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2021-10-20

Completion:

2026-12-10

Conditions

• Cardiovascular (CV) Risk

No Results Yet

NCT04002947 | RECRUITING | PHASE2

132 participants

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-08-05

Completion:

2027-05-31

Conditions

• Non-Hodgkin's Lymphoma
• Diffuse Large B-Cell Lymphoma
• DLBCL
• NHL

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03987555 | SUSPENDED

55 participants

Paclitaxel Therapeutic Drug Monitoring in Cancer Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2019-11-11

Completion:

2027-05-31

Conditions

• Solid Tumor, Adult
• Metastatic Nonsmall Cell Lung Cancer
• Anatomic Stage IV Breast Cancer AJCC v8
• Metastatic Cervical Carcinoma
• Metastatic Ovarian Carcinoma
• Malignant Uterine Neoplasm
• Vulvar Cancer
• Invasive Breast Cancer
• Metastatic Breast Carcinoma
• Prognostic Stage IV Breast Cancer AJCC v8
• Recurrent Breast Carcinoma
• Recurrent Cervical Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Recurrent Ovarian Carcinoma
• Recurrent Vulvar Carcinoma
• Stage IV Cervical Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IV Vulvar Cancer AJCC v8
• Stage IV Ovarian Cancer AJCC v8
• Stage IVA Cervical Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVA Ovarian Cancer AJCC v8
• Stage IVA Vulvar Cancer AJCC v8
• Stage IVB Cervical Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8
• Stage IVB Ovarian Cancer AJCC v8
• Stage IVB Vulvar Cancer AJCC v8
• Vulva Squamous Cell Carcinoma

Interventions

• OTHER

No Results Yet

NCT03962127 | ACTIVE_NOT_RECRUITING

800 participants

MIDNOR-STROKE- a Long Term Follow-up Study of Patients With First Ever Ischemic Stroke in Central Norway

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2015-05-01

Completion:

2026-08-31

Conditions

• Stroke
• Cardiovascular Diseases
• Cardiovascular Risk Factor
• Brain Ischemia
• Cerebrovascular Disorders
• Nervous System Diseases
• Central Nervous System Lymphoma
• Pathologic Processes
• Vascular Diseases

Interventions

• OTHER

No Results Yet

NCT03952598 | SUSPENDED | PHASE2

42 participants

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-10-16

Completion:

2027-12-31

Conditions

• Glioma
• Gliomas
• High Grade Glioma
• Malignant Glioma
• Low Grade Glioma

Interventions

• DRUG
• DEVICE

No Results Yet

NCT03924817 | ACTIVE_NOT_RECRUITING

500 participants

Registry Study on Prescription, Patient Pathways, Therapy Efficacy and Usage of Mandibular Advancement Devices in Obstructive Sleep Apnea - PATT-OSA Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2024-02-01

Completion:

2026-10-31

Conditions

• Obstructive Sleep Apnea

No Results Yet

NCT03921944 | RECRUITING | NA

30 participants

Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2024-05-02

Completion:

2028-09-30

Conditions

• Osteoarthritis of Shoulder

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03911128 | RECRUITING

500 participants

A Treatment Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2019-08-29

Completion:

2033-06-30

Conditions

• Leukemia, Acute Lymphoblastic

Interventions

• OTHER

No Results Yet

NCT03878446 | ACTIVE_NOT_RECRUITING | PHASE2

62 participants

A Research Study in Children Born Small and Who Stayed Small. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-07-04

Completion:

2021-05-05

Conditions

• Short Stature Children Born Small for Gestational Age (SGA)

Interventions

• DRUG

Results Available

NCT03871257 | ACTIVE_NOT_RECRUITING | PHASE3

165 participants

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2020-01-15

Completion:

2027-12-31

Conditions

• Low Grade Glioma
• Neurofibromatosis Type 1
• Visual Pathway Glioma

Interventions

• DRUG
• PROCEDURE
• OTHER

No Results Yet

NCT03858322 | ACTIVE_NOT_RECRUITING | PHASE1

41 participants

'ADVANCE' (A Pilot Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-03-21

Completion:

2020-11-10

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT03841617 | RECRUITING | PHASE2

30 participants

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-07-29

Completion:

2035-11-01

Conditions

• Thyroid Cancer

Interventions

• DRUG
• RADIATION
• OTHER

No Results Yet

NCT03831958 | RECRUITING

600 participants

Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2019-03-04

Completion:

2040-01-03

Conditions

• Cushing Disease

No Results Yet

NCT03827343 | ACTIVE_NOT_RECRUITING

500 participants

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2019-01-23

Completion:

2026-12-31

Conditions

• Macrophage Activation Syndrome
• Primary Hemophagocytic Lymphohistiocytosis

No Results Yet

NCT03814746 | ACTIVE_NOT_RECRUITING | PHASE3

254 participants

Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-07-26

Completion:

2022-08-31

Conditions

• Sickle Cell Disease (SCD)

Interventions

• DRUG

Results Available

NCT03813407 | RECRUITING | PHASE3

140 participants

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-04-02

Completion:

2030-02-21

Conditions

• Hyperkalaemia

Interventions

• DRUG

No Results Yet

NCT03805919 | RECRUITING

500 participants

Men at High Genetic Risk for Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2019-03-27

Completion:

2029-01-01

Conditions

• Prostatic Neoplasms

No Results Yet

NCT03790098 | COMPLETED | NA

38 participants

Flow-Restorative Yoga to Decrease Pain and Inflammation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-11-19

Completion:

2019-04-27

Conditions

• Pain
• Inflammation

Interventions

• BEHAVIORAL

No Results Yet

NCT03782207 | COMPLETED

2756 participants

A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2019-02-07

Completion:

2026-07-31

Conditions

• Urothelial Carcinoma
• Non-Small Cell Lung Cancer
• Small Cell Lung Cancer
• Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT03737955 | RECRUITING | PHASE2

36 participants

Fractionated Gemtuzumab Ozogamicin in Treating Measurable Residual Disease in Patients With Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-11-30

Completion:

2026-12-31

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG
• OTHER
• PROCEDURE

No Results Yet

NCT03678389 | RECRUITING | NA

70 participants

Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-05-09

Completion:

2028-03-01

Conditions

• Pituitary Neoplasm

Interventions

• OTHER

No Results Yet

NCT03660826 | ACTIVE_NOT_RECRUITING | PHASE2

288 participants

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-09-27

Completion:

2024-12-06

Conditions

• Endometrial Adenocarcinoma
• Endometrial Mixed Cell Adenocarcinoma
• Endometrial Serous Adenocarcinoma
• Endometrial Undifferentiated Carcinoma
• Endometrioid Adenocarcinoma
• Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT03653338 | RECRUITING | PHASE1/PHASE2

5 participants

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-08-02

Completion:

2028-08-01

Conditions

• Sickle Cell Anemia
• Beta-thalassemia Major
• Diamond-blackfan Anemia

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT03649555 | COMPLETED | PHASE1

5 participants

Reliability of [18F]-FTC-146 Brain Uptake in Healthy Controls

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-02-01

Completion:

2020-03-03

Conditions

• Healthy Controls

Interventions

• DRUG

No Results Yet

NCT03632239 | ENROLLING_BY_INVITATION

1000 participants

Reverse Phenotyping Core

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-13

Start Date:

2020-01-23

Completion:

2028-06-01

Conditions

• Harboring of Unexpected Genetic Variant

No Results Yet

NCT03624660 | ACTIVE_NOT_RECRUITING | PHASE2

100 participants

Dose-Escalated Proton Radiation Therapy for High-Risk Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-09-24

Completion:

2029-09-30

Conditions

• Adenocarcinoma of the Prostate

Interventions

• RADIATION

No Results Yet

NCT03604991 | SUSPENDED | PHASE2/PHASE3

278 participants

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2019-05-03

Completion:

2026-12-31

Conditions

• Clinical Stage II Esophageal Adenocarcinoma AJCC v8
• Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Esophageal Adenocarcinoma
• Gastroesophageal Junction Adenocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT03604198 | ACTIVE_NOT_RECRUITING | PHASE2

125 participants

Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-13

Start Date:

2018-05-07

Completion:

2026-12-31

Conditions

• Cushing Syndrome

Interventions

• DRUG

No Results Yet