Clinical Trials

NCT07372625 | RECRUITING | PHASE1

14 participants

A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-02-04

Completion:

2027-03-31

Conditions

• TP53 Y220C Mutation
• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT07370311 | RECRUITING | NA

60 participants

A Culturally Adapted Decision Aid Intervention to Support Chinese American Dementia Caregivers in Feeding-Related Decisions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-03-24

Completion:

2027-06-30

Conditions

• Dementia Caregivers
• End of Life Decision Making
• Advanced Dementia

Interventions

• OTHER

No Results Yet

NCT07365865 | COMPLETED | NA

36 participants

Dimensional Changes of the Keratinized Mucosa in Edentulous Ridges Following Accordian Technique Versus Conventional Free Gingival Grafts

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2024-08-14

Completion:

2026-03-01

Conditions

• Deficient Keratinized Mucosa
• Healthy

Interventions

• PROCEDURE

No Results Yet

NCT07359157 | RECRUITING | NA

40 participants

Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-02-05

Completion:

2027-05-01

Conditions

• Serious Mental Illness
• Psychotic Disorder
• Depression
• Bipolar

Interventions

• BEHAVIORAL

No Results Yet

NCT07348666 | RECRUITING | NA

100 participants

A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-06-18

Completion:

2027-12-01

Conditions

• Suicide
• Mental Health Disorder
• Anhedonia

Interventions

• BEHAVIORAL

No Results Yet

NCT07347548 | COMPLETED | PHASE1

24 participants

A Trial to Investigate the Safety and Pharmacokinetics of GRT6019 in Healthy Male Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-01-06

Completion:

2026-06-09

Conditions

• Duchenne Muscular Dystrophy (DMD)

Interventions

• DRUG

No Results Yet

NCT07347379 | ENROLLING_BY_INVITATION

108 participants

Long-Term Clinical Outcomes Of Subjects Enrolled In The RxSight Light Adjustable Lens (LAL) And Light Delivery Device (LDD) New Enrollment Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2025-11-13

Completion:

2026-09-30

Conditions

• Aphakia Cataract

Interventions

• DEVICE

No Results Yet

NCT07346326 | ACTIVE_NOT_RECRUITING | NA

64 participants

Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-01-01

Completion:

2026-07-28

Conditions

• Anterior Cruciate Ligament Injuries

Interventions

• PROCEDURE

No Results Yet

NCT07340697 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

24 participants

Evaluate RLS-1496 Topical Cream for Actinic Keratosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-02-03

Completion:

2026-05-27

Conditions

• Actinic Keratosis (AK)

Interventions

• DRUG

No Results Yet

NCT07336992 | NOT_YET_RECRUITING | PHASE3

580 participants

Efficacy of Prophylactic Levetiracetam for Improving Functional Outcome in the Acute Phase of Intracerebral Haemorrhage: a Randomised, Double-blind, Placebo-controlled, Phase 3 Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-10-02

Completion:

2030-04-02

Conditions

• Spontaneous Intracerebral Hemorrhage

Interventions

• DRUG
• RADIATION
• DIAGNOSTIC_TEST
• BEHAVIORAL

No Results Yet

NCT07335484 | RECRUITING | NA

75 participants

Aquarius Pilot Study to Evaluate the New Axonics Trial System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-04-30

Completion:

2026-09-30

Conditions

• Urinary Urge Incontinence (UUI)
• Urinary Frequency (UF)
• Fecal Incontinence (FI)
• Overactive Bladder (OAB)

Interventions

• DEVICE

No Results Yet

NCT07324629 | RECRUITING | PHASE2

30 participants

Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-03-13

Completion:

2028-04-30

Conditions

• Thymic Carcinoma

Interventions

• DRUG

No Results Yet

NCT07324499 | RECRUITING | NA

40 participants

Effect of Dexamethasone on Plasma Levels of Bupivacaine and Dexamethasone After a Single-injection Interscalene Nerve Block.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-05-19

Completion:

2026-12-01

Conditions

• Pain
• Interscalene Blocks
• Dexamethasone
• Bupivacaine

Interventions

• DRUG

No Results Yet

NCT07324200 | COMPLETED

71 participants

Objective Assessment of Intraocular Lens Tilt and Decentration

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2026-03-03

Completion:

2026-06-26

Conditions

• Tilt and Decentration

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT07322198 | ENROLLING_BY_INVITATION | NA

42 participants

Effects of Gong's Mobilization With and Without Scapular High Lift on Shoulder Range of Motion and Functional Recovery in Adhesive Capsulitis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-03-01

Completion:

2026-03-30

Conditions

• Adhesive Capsulitis

Interventions

• OTHER

No Results Yet

NCT07322185 | ENROLLING_BY_INVITATION | NA

42 participants

Comparative Effects of Stecco-fascial Manipulation and Rolfing Structural Integration in Patients With Piriformis Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-03-01

Completion:

2026-03-30

Conditions

• Piriformis Syndrome

Interventions

• OTHER

No Results Yet

NCT07316062 | RECRUITING

3000 participants

A Multi-centre Chart Review Study of Stage I-III Non-Small Cell Lung Cancer in China

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2026-04-29

Completion:

2029-04-30

Conditions

• Non-Small-Cell Lung

No Results Yet

NCT07312877 | COMPLETED

138 participants

Comparison of the Effectiveness of Intraoperative Intravenous Lidocaine and Intravenous Remifentanil in Postoperative Pain Management in Laparoscopic Cholecystectomy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2025-04-01

Completion:

2025-11-25

Conditions

• Colicystitis

Interventions

• DRUG

No Results Yet

NCT07311746 | RECRUITING | PHASE1/PHASE2

36 participants

Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-04-28

Completion:

2029-01-31

Conditions

• T-cell Prolymphocytic Leukemia
• Refractory T-Cell Prolymphocytic Leukemia

Interventions

• DRUG

No Results Yet

NCT07310368 | COMPLETED | NA

47 participants

Mobilization Versus Myofascial Release in Sacroiliac Joint Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-01-19

Completion:

2026-03-20

Conditions

• Sacroiliac Joint Dysfunction

Interventions

• OTHER

No Results Yet

NCT07310082 | NOT_YET_RECRUITING | NA

156 participants

Allograft vs. Autograft Nonunion

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-08-31

Completion:

2030-12-31

Conditions

• Nonunion Fracture

Interventions

• PROCEDURE

No Results Yet

NCT07301424 | NOT_YET_RECRUITING | PHASE2

80 participants

Subcutaneous Blinatumomab Plus Ponatinib for BCR-ABL+ B-ALL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2027-01-02

Completion:

2027-12-31

Conditions

• Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)
• BCR-ABL Positive Acute Lymphoblastic Leukemia

Interventions

• DRUG

No Results Yet

NCT07300995 | RECRUITING | NA

168 participants

Behavioral Pain Intervention for Older Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-06-17

Completion:

2027-04-30

Conditions

• Breast Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT07299006 | RECRUITING | NA

120 participants

Evaluation of Paro, a Therapeutic Assistance Robot in Analgesic Management During the Placement of a Peripheral Intravenous Line in Infants and Children.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-03-03

Completion:

2027-03-30

Conditions

• Pain Management

Interventions

• DEVICE
• OTHER

No Results Yet

NCT07297667 | RECRUITING | PHASE1

30 participants

GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-07-30

Completion:

2028-12-01

Conditions

• Alveolar Soft Part Sarcoma
• Renal Cell Carcinoma
• Triple Negative Breast Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT07295990 | RECRUITING | NA

20 participants

Tongue-strengthening Exercises in People With ALS.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-05-01

Completion:

2028-12-31

Conditions

• ALS (Amyotrophic Lateral Sclerosis)
• ALS - Amyotrophic Lateral Sclerosis

Interventions

• PROCEDURE

No Results Yet

NCT07295717 | RECRUITING | PHASE1

76 participants

A Study to Evaluate ALN-4285 in Adult Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-12-12

Completion:

2026-12-29

Conditions

• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT07291895 | NOT_YET_RECRUITING | NA

21 participants

High Dose Radiotherapy for Palliation (Hi-D)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2027-03-01

Completion:

2030-07-01

Conditions

• Metastases
• Palliative Radiotherapy

Interventions

• RADIATION

No Results Yet

NCT07288112 | RECRUITING | PHASE1/PHASE2

35 participants

DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-04-06

Completion:

2031-01-31

Conditions

• Refractory Melanoma

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT07285213 | RECRUITING | PHASE2

230 participants

Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-12-10

Completion:

2027-04-20

Conditions

• Clostridioides Difficile Infection

Interventions

• DRUG
• OTHER

No Results Yet

NCT07285122 | RECRUITING | PHASE1

105 participants

Inhaled RB042 in Healthy Adult Volunteers, Healthy Adult Smokers and Patients With Chronic Obstructive Pulmonary Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-02-16

Completion:

2027-10-31

Conditions

• COPD
• Healthy
• Healthy Smoker
• COPD (Chronic Obstructive Pulmonary Disease)

Interventions

• DRUG

No Results Yet

NCT07283640 | NOT_YET_RECRUITING | PHASE1

20 participants

A Phase IB Trial of Subcutaneous Blinatumomab in Combination With Revumenib for Patients With KMT2A-rearranged Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-11-18

Completion:

2029-08-31

Conditions

• Blinatumomab
• Revumenib
• Lymphoblastic Leukemia
• KMT2A-rearranged

Interventions

• DRUG

No Results Yet

NCT07281079 | RECRUITING | PHASE3

160 participants

A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-11-12

Completion:

2027-10-31

Conditions

• Phelan-McDermid Syndrome

Interventions

• DRUG

No Results Yet

NCT07280780 | NOT_YET_RECRUITING

36 participants

CGM-Based Glycemic Analysis After ESI

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2026-08-05

Completion:

2026-12-20

Conditions

• Type 2 Diabetes (T2DM)
• Hyperglycemia
• Radicular Pain
• Spinal Stenosis
• Intervertebral Disc Herniation

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT07280013 | RECRUITING | PHASE1

60 participants

A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-02-06

Completion:

2028-12-31

Conditions

• Multiple Myeloma (MM)

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT07279753 | COMPLETED | NA

13 participants

Critical Thinking Tactical Training in University Futsal Players

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-10-09

Completion:

2025-11-03

Conditions

• Athletic Performance
• Decision Making

Interventions

• OTHER

No Results Yet

NCT07277322 | RECRUITING | PHASE1/PHASE2

24 participants

Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-09-01

Completion:

2028-12-31

Conditions

• Metastatic Colorectal Cancer
• Liver Metastases

Interventions

• DRUG

No Results Yet

NCT07272642 | NOT_YET_RECRUITING | PHASE1

16 participants

A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-10-30

Completion:

2027-08-30

Conditions

• Imaging
• Colorectal Cancer
• Head and Neck Squamous Cell Carcinoma
• Non-Small Cell Lung Cancer
• Triple Negative Breast Cancer (TNBC)

Interventions

• DRUG

No Results Yet

NCT07265479 | ACTIVE_NOT_RECRUITING | PHASE3

187 participants

A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2025-12-29

Completion:

2027-08-31

Conditions

• Atopic Dermatitis

Interventions

• DRUG

No Results Yet

NCT07264283 | ENROLLING_BY_INVITATION | PHASE2

147 participants

The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen B: LM11A-31

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2026-07-29

Completion:

2030-09-28

Conditions

• PSP - Progressive Supranuclear Palsy

Interventions

• DRUG

No Results Yet