Clinical Trials

NCT04225871 | COMPLETED | PHASE3

200 participants

Open-Label Extension of Zilucoplan in Subjects With Generalized Myasthenia Gravis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-12-23
Completion:: 2026-07-31

Conditions

Generalized Myasthenia Gravis

Interventions

DRUG

No Results Yet

NCT04208685 | COMPLETED

202 participants

Evaluating Cognitive Outcomes in Down Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-06-18
Completion:: 2024-06-14

Conditions

Down Syndrome

No Results Yet

NCT04204252 | TERMINATED | PHASE3

98 participants

Phase III, Efficacy and Safety of "Kamada-AAT for Inhalation"

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-11-25
Completion:: 2026-02-19

Conditions

Alpha 1-Antitrypsin Deficiency

Interventions

DRUG

No Results Yet

NCT04200937 | ENROLLING_BY_INVITATION

450 participants

IT Matters: The Erectile Restoration Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-08-05
Completion:: 2031-01-31

Conditions

Erectile Dysfunction

Interventions

DEVICE

No Results Yet

NCT04199741 | RECRUITING | PHASE1/PHASE2

105 participants

PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-12-11
Completion:: 2027-06-11

Conditions

Small Cell Lung Cancer
Small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT04171856 | RECRUITING | NA

245 participants

Exploring Motor Learning in Acute Stroke Through Robotics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2020-01-01
Completion:: 2030-05-01

Conditions

Stroke, Acute

Interventions

DEVICE

No Results Yet

NCT04168970 | COMPLETED

62 participants

Percutaneous Left Stellate Ganglion Block In Out-of-hospital Cardiac Arrest Due to Refractory VEntricular Arrhythmias (LIVE Study)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-06-12
Completion:: 2025-12-31

Conditions

Out-Of-Hospital Cardiac Arrest
Ventricular Fibrillation Sustained
Shockable Rhythm
Medical Etiology
Refractory Ventricular Arrhythmias

Interventions

PROCEDURE

No Results Yet

NCT04157348 | ACTIVE_NOT_RECRUITING | PHASE3

140 participants

Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-10-29
Completion:: 2023-08-10

Conditions

Eosinophilic Granulomatous Vasculitis

Interventions

BIOLOGICAL

Results Available

NCT04153682 | COMPLETED | NA

116 participants

Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients With Hospital-acquired Pneumonia.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2020-02-21
Completion:: 2023-08-31

Conditions

Hospital-acquired Pneumonia

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04126070 | ACTIVE_NOT_RECRUITING | PHASE2

47 participants

Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2020-05-11
Completion:: 2025-07-29

Conditions

Hormone Sensitive Prostate Cancer
Prostate Adenocarcinoma
Metastasis Prostate Adenocarcinoma

Interventions

DRUG

Results Available

NCT04115163 | ACTIVE_NOT_RECRUITING | PHASE2

67 participants

Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2020-06-24
Completion:: 2026-12-31

Conditions

Metastatic Pancreatic Adenocarcinoma
Stage IV Pancreatic Cancer AJCC v8

Interventions

DRUG

No Results Yet

NCT04044859 | ACTIVE_NOT_RECRUITING | PHASE1

120 participants

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-08-20
Completion:: 2026-12-23

Conditions

Endometrial Cancer
Esophageal Cancer
Esophagogastric Junction (EGJ)
Gastric (Stomach) Cancer
Head and Neck Cancer
Melanoma
Ovarian Cancer
Non-small Cell Lung (NSCLC)
Urothelial Cancer

Interventions

GENETIC

No Results Yet

NCT04040452 | RECRUITING | PHASE4

166 participants

Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-03-01
Completion:: 2027-10-01

Conditions

Congenital Heart Disease in Children

Interventions

DRUG

No Results Yet

NCT04030273 | COMPLETED

62 participants

Prevalence of Intrauterine Adhesions After Myomectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2020-01-21
Completion:: 2021-03-29

Conditions

Myoma;Uterus

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04017819 | SUSPENDED | PHASE1

20 participants

Biodistribution & Pharmacokinetic of Position Emission Tomography (PET) Radiopharmaceutical 18F C SNAT4

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-03-07
Completion:: 2026-12-31

Conditions

Cancer
Lung Cancer

Interventions

DRUG
DEVICE

No Results Yet

NCT04007770 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Acupuncture Pilot Study for Cancer-related Cognitive Function

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-07-01
Completion:: 2027-07-31

Conditions

Stage I Breast Cancer
Stage II Breast Cancer
Stage III Breast Cancer
Stage I Colorectal Cancer
Stage II Colorectal Cancer
Stage III Colorectal Cancer
Gynecologic Cancer
Stage I Gynecologic Cancer
Stage II Gynecologic Cancer
Stage III Gynecologic Cancer
Stage I Prostate Cancer
Stage II Prostate Cancer
Stage III Prostate Cancer

Interventions

OTHER

No Results Yet

NCT04007640 | TERMINATED | NA

41 participants

Early Screening of Pancreatic Lesions : Development of New Imaging Tools

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-06-18
Completion:: 2023-05-31

Conditions

Pancreatic Cancer

Interventions

RADIATION
PROCEDURE

No Results Yet

NCT03995043 | NOT_YET_RECRUITING | NA

198 participants

Project for Reproductive Equity Through Volunteers and Entrepreneurship, Networks and Technology

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2027-12-31
Completion:: 2028-12-01

Conditions

Contraception
Pregnancy Related
Reproductive Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT03986034 | RECRUITING | PHASE2

75 participants

Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-06-26
Completion:: 2026-11-17

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG

No Results Yet

NCT03943173 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

15 participants

Olaparib in Treating Patients With Newly Diagnosed BRCA-Mutant Ovarian, Primary Peritoneal, or Fallopian Cancer Before Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-06-07
Completion:: 2027-06-27

Conditions

BRCA-Mutated Ovarian Carcinoma
BRCA1 Gene Mutation
BRCA2 Gene Mutation
High Grade Fallopian Tube Serous Adenocarcinoma
High Grade Ovarian Serous Adenocarcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Stage III Fallopian Tube Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage III Primary Peritoneal Cancer AJCC v8
Stage IIIA Fallopian Tube Cancer AJCC v8
Stage IIIA Ovarian Cancer AJCC v8
Stage IIIA Primary Peritoneal Cancer AJCC v8
Stage IIIA1 Fallopian Tube Cancer AJCC v8
Stage IIIA1 Ovarian Cancer AJCC v8
Stage IIIA2 Fallopian Tube Cancer AJCC v8
Stage IIIA2 Ovarian Cancer AJCC v8
Stage IIIB Fallopian Tube Cancer AJCC v8
Stage IIIB Ovarian Cancer AJCC v8
Stage IIIB Primary Peritoneal Cancer AJCC v8
Stage IIIC Fallopian Tube Cancer AJCC v8
Stage IIIC Ovarian Cancer AJCC v8
Stage IIIC Primary Peritoneal Cancer AJCC v8
Stage IV Fallopian Tube Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8
Stage IV Primary Peritoneal Cancer AJCC v8
Stage IVA Fallopian Tube Cancer AJCC v8
Stage IVA Ovarian Cancer AJCC v8
Stage IVA Primary Peritoneal Cancer AJCC v8
Stage IVB Fallopian Tube Cancer AJCC v8
Stage IVB Ovarian Cancer AJCC v8
Stage IVB Primary Peritoneal Cancer AJCC v8

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03941925 | COMPLETED | NA

100 participants

Prebiotic Fructans Effect on 1-3 Years Constipated Children's Bowel Habits

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-08-19
Completion:: 2021-10-26

Conditions

Constipation

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT03917927 | COMPLETED | NA

82 participants

A Clinical Study of the Eztetic Dental Implant System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-01-08
Completion:: 2023-05-30

Conditions

Edentulous Jaw

Interventions

DEVICE

Results Available

NCT03892824 | ACTIVE_NOT_RECRUITING | NA

100 participants

Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-04-15
Completion:: 2024-10-24

Conditions

Atrial Fibrillation
Stroke

Interventions

DEVICE

No Results Yet

NCT03883412 | RECRUITING | PHASE4

60 participants

Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-02-28
Completion:: 2027-06-30

Conditions

Type2 Diabetes

Interventions

OTHER
DRUG

No Results Yet

NCT03854318 | RECRUITING

1000 participants

Longitudinal Studies of Patient With FPDMM

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-03-28
Completion:: 2028-12-31

Conditions

Inherited Hematological Diseases
Rare Diseases
FPDMM

No Results Yet

NCT03847285 | ACTIVE_NOT_RECRUITING

188 participants

Immune Function as Predictor of Infectious Complications and Clinical Outcome in Patients Undergoing Solid Organ Transplantation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-04-01
Completion:: 2022-01-31

Conditions

Transplant

Interventions

OTHER

No Results Yet

NCT03809351 | RECRUITING | PHASE1

160 participants

UAB Alzheimer's Disease Center Core Cohort - Tau Imaging Substudy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2020-07-08
Completion:: 2028-07-31

Conditions

Alzheimer Disease

Interventions

DRUG

No Results Yet

NCT03807531 | ACTIVE_NOT_RECRUITING | NA

100 participants

A Study of the Temporary Spur Stent for the Treatment of Narrowing and Blockages in the Arteries Below the Knee

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-07-11
Completion:: 2023-04-30

Conditions

Peripheral Arterial Disease

Interventions

DEVICE

No Results Yet

NCT03696030 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-11-27
Completion:: 2027-01-24

Conditions

Malignant Neoplasm
Metastatic Malignant Neoplasm in the Brain
Metastatic Malignant Neoplasm in the Leptomeninges
Breast Cancer
HER2-positive Breast Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT03680677 | RECRUITING

20 participants

Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-09-21
Completion:: 2027-09-30

Conditions

Leukemia, Acute
MDS

Interventions

PROCEDURE
OTHER
DIAGNOSTIC_TEST

No Results Yet

NCT03678480 | WITHDRAWN | PHASE2

0 participants

A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2021-03-01
Completion:: 2021-10-04

Conditions

Primary Sclerosing Cholangitis
Cholangitis
Cholangitis, Sclerosing
Bile Duct Diseases
Biliary Tract Diseases
Digestive System Diseases
Adolescent

Interventions

DRUG

No Results Yet

NCT03649659 | TERMINATED | PHASE3

830 participants

Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-10-08
Completion:: 2023-04-11

Conditions

Cavities of Teeth

Interventions

DRUG

Results Available

NCT03584802 | TERMINATED | NA

5 participants

Therapeutic Plasma Exchange, Rituximab and IV Ig for Severe Acute Exacerbation of IPF Admitted in ICU

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-05-16
Completion:: 2019-11-15

Conditions

Exacerbation of Idiopathic Pulmonary Fibrosis

Interventions

OTHER

No Results Yet

NCT03578185 | RECRUITING

2000 participants

Genomic Analysis to Identify a Predictive Biomarker for Immunotherapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-04-11
Completion:: 2030-12-31

Conditions

Lung Cancer

No Results Yet

NCT03566667 | COMPLETED | PHASE4

1713 participants

Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-06-12
Completion:: 2025-12-29

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

DRUG

No Results Yet

NCT03545386 | COMPLETED | PHASE2

47 participants

Fecal Microbiota Transplantation for Pouchitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2019-04-17
Completion:: 2026-03-31

Conditions

Pouchitis

Interventions

OTHER

No Results Yet

NCT03503331 | RECRUITING | PHASE2

160 participants

UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-04-20
Completion:: 2028-10-31

Conditions

Alzheimer Disease

Interventions

DRUG

No Results Yet

NCT03457493 | RECRUITING | PHASE1/PHASE2

205 participants

The University of Alabama at Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-03-22
Completion:: 2028-06-30

Conditions

Parkinson Disease

Interventions

DRUG

No Results Yet

NCT03440567 | COMPLETED | PHASE1

16 participants

Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-04-02
Completion:: 2024-06-24

Conditions

Recurrent Diffuse Large B-Cell Lymphoma
Recurrent Mantle Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma
Refractory Mantle Cell Lymphoma
Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma

Interventions

PROCEDURE
DRUG
OTHER
BIOLOGICAL

No Results Yet

NCT03429036 | RECRUITING

1000 participants

Biospecimen Procurement for Head and Neck Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2018-05-23
Completion:: 2029-06-03

Conditions

Hearing Disorder
Oral Mucosal Disease
Pharyngeal Neoplasm
Head and Neck Neoplasms
Laryngeal Disease

No Results Yet