Clinical Trials

NCT07249034 | NOT_YET_RECRUITING | NA

50 participants

Impact of Epilepsy on the Brainstem Adenosine Pathway and Its Relation With Arousal and Respiratory Reactivity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-08-07
Completion:: 2028-08-07

Conditions

Epilepsy
Drug-resistant Focal Epilepsy
Healthy Controls

Interventions

PROCEDURE

No Results Yet

NCT07246226 | COMPLETED | NA

22 participants

Communication in the Surgical Environment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-12-20
Completion:: 2026-01-30

Conditions

Communication in the Surgical Environment

Interventions

BEHAVIORAL

No Results Yet

NCT07245992 | RECRUITING | PHASE1

42 participants

A Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-03-04
Completion:: 2028-09-30

Conditions

Rheumatoid Arthritis (RA)

Interventions

DRUG

No Results Yet

NCT07239596 | RECRUITING | PHASE1/PHASE2

92 participants

Phase Ib/II Clinical Study of SHR-8068 Combined Anti-tumor Drugs in the Treatment of Advanced Renal Cell Carcinom

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-01-06
Completion:: 2030-12-31

Conditions

Advanced Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07238699 | COMPLETED | NA

124 participants

An Evaluation of the Safety and Tolerability of Ocular Lubricants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-03-04
Completion:: 2026-07-22

Conditions

Dry Eye Disease

Interventions

OTHER

No Results Yet

NCT07234500 | COMPLETED | NA

50 participants

Evaluation of a Mobile Application Designed to Support Type 1 Diabetic Patients in Adjusting Their Insulin Doses.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-09-01
Completion:: 2026-06-30

Conditions

Type One Diabetes Mellitus

Interventions

DEVICE
OTHER

No Results Yet

NCT07234058 | RECRUITING | PHASE2

126 participants

Trial Assessing Fianlimab Plus Cemiplimab Plus Chemotherapy or Cemiplimab Plus Chemotherapy in Patients With Pleural Mesothelioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-04-02
Completion:: 2028-05-31

Conditions

Pleural Mesotheliomas

Interventions

DRUG

No Results Yet

NCT07233239 | RECRUITING | PHASE1

100 participants

A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-11-26
Completion:: 2027-11-29

Conditions

Focal Seizures

Interventions

DRUG

No Results Yet

NCT07232069 | RECRUITING | PHASE3

1500 participants

PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-07-21
Completion:: 2031-07-31

Conditions

Coronary Artery Disease Risk Factors Multiple
Coronary Artery Disease Progression
Prevention & Control
Premature Atherosclerosis

Interventions

DRUG

No Results Yet

NCT07232030 | ENROLLING_BY_INVITATION | NA

2500 participants

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-04-24
Completion:: 2033-01-31

Conditions

Heart Failure
Heart Failure NYHA Class II
Heart Failure NYHA Class III

Interventions

DEVICE
OTHER

No Results Yet

NCT07231536 | COMPLETED | NA

367 participants

Boosting Executive Function With Real-class Exercise

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-11-24
Completion:: 2025-12-26

Conditions

Executive Functions (EF)

Interventions

BEHAVIORAL

No Results Yet

NCT07228117 | RECRUITING | NA

400 participants

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-02-02
Completion:: 2027-01-31

Conditions

Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus

Interventions

DEVICE

No Results Yet

NCT07228065 | ENROLLING_BY_INVITATION | NA

720 participants

Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-08-07
Completion:: 2027-04-30

Conditions

Hypertension
Primary Care

Interventions

BEHAVIORAL

No Results Yet

NCT07227857 | RECRUITING | PHASE1/PHASE2

20 participants

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-11-24
Completion:: 2028-04-15

Conditions

Epileptic Encephalopathy

Interventions

DRUG

No Results Yet

NCT07224711 | NOT_YET_RECRUITING | PHASE4

2290 participants

The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-10-31
Completion:: 2028-10-31

Conditions

Pain
Post Operative Analgesia
Opioid Consumption, Postoperative

Interventions

DRUG

No Results Yet

NCT07224698 | NOT_YET_RECRUITING | PHASE2

320 participants

Inhaled Cannabis for Treatment of PTSD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2027-02-28
Completion:: 2028-10-31

Conditions

Post Traumatic Stress Disorder PTSD

Interventions

DRUG

No Results Yet

NCT07224009 | NOT_YET_RECRUITING | PHASE2

60 participants

Low Dose Naltrexone (LDN) for Management of Fatigue in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-08-31
Completion:: 2029-01-31

Conditions

Metastatic Prostate Cancer

Interventions

DRUG

No Results Yet

NCT07221851 | RECRUITING | PHASE3

186 participants

Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-12-12
Completion:: 2028-02-29

Conditions

Turner Syndrome
Short Stature Homeobox Gene Mutation
Idiopathic Short Stature
Small for Gestational Age at Delivery

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07221669 | RECRUITING | PHASE3

30 participants

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-04-28
Completion:: 2028-11-28

Conditions

Muscular Atrophy, Spinal

Interventions

DRUG

No Results Yet

NCT07219342 | COMPLETED | NA

109 participants

The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains) Over 8 Weeks of Unsupervised Use.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-09-11
Completion:: 2025-11-06

Conditions

Teeth Staining

Interventions

OTHER

No Results Yet

NCT07218094 | ENROLLING_BY_INVITATION | NA

22 participants

Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-09-11
Completion:: 2027-02-28

Conditions

Stroke

Interventions

DEVICE

No Results Yet

NCT07214571 | RECRUITING | PHASE2

192 participants

A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-12-11
Completion:: 2026-12-30

Conditions

Respiratory Syncytial Virus Infections

Interventions

DRUG

No Results Yet

NCT07214428 | ACTIVE_NOT_RECRUITING | NA

50 participants

Effects of Grape Powder on Psychological Distress and Gut Microbiota in College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-10-20
Completion:: 2025-12-24

Conditions

Gut Microbiota
Psychological Distress

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07214038 | COMPLETED | NA

120 participants

A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-09-01
Completion:: 2025-10-01

Conditions

Teeth Color
Teeth Staining

Interventions

OTHER

No Results Yet

NCT07204977 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-02-02
Completion:: 2027-09-30

Conditions

Amyotrophic Lateral Sclerosis
Motor Neuron Disease

Interventions

DRUG

No Results Yet

NCT07199036 | COMPLETED | NA

300 participants

Clinical Application of the Effect of Respiratory Muscles Electrical Stimulation on Weaning in Patients With Difficult Weaning of the Mechanical Ventilation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-09-29
Completion:: 2025-11-01

Conditions

Mechanical Ventilation

Interventions

DEVICE

No Results Yet

NCT07195734 | RECRUITING | PHASE2

180 participants

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-04-24
Completion:: 2033-02-01

Conditions

Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Locally Recurrent Head and Neck Squamous Cell Carcinoma
Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma
Locally Recurrent Laryngeal Squamous Cell Carcinoma
Locally Recurrent Oral Cavity Squamous Cell Carcinoma
Locally Recurrent Oropharyngeal Squamous Cell Carcinoma
Stage II Laryngeal Cancer AJCC v8
Stage II Lip and Oral Cavity Cancer AJCC v8
Stage II Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage III Laryngeal Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVA Laryngeal Cancer AJCC v8
Stage IVA Lip and Oral Cavity Cancer AJCC v8
Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Stage IVB Laryngeal Cancer AJCC v8
Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL
RADIATION

No Results Yet

NCT07195682 | RECRUITING | PHASE1

281 participants

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-01-15
Completion:: 2030-05-03

Conditions

Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07191249 | RECRUITING | PHASE2

40 participants

Trial to Evaluate Efficacy and Safety of Subcutaneous Mosunetuzumab in Previously Untreated Low Tumor Burden Follicular Lymphoma .

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-01-05
Completion:: 2028-04-01

Conditions

Follicular Lymphoma

Interventions

DRUG

No Results Yet

NCT07190807 | RECRUITING | NA

70 participants

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-11-07
Completion:: 2027-11-30

Conditions

Chronic Pain
Intractable Pain
Low Back Pain
Chronic Low-back Pain
Chronic Leg Pain
Leg Pain

Interventions

DEVICE

No Results Yet

NCT07188844 | TERMINATED | PHASE2

26 participants

An Open-Label Extension Study of Batoclimab in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-08-28
Completion:: 2026-07-16

Conditions

Chronic Inflammatory Demyelinating Polyneuropathy

Interventions

DRUG

No Results Yet

NCT07187869 | RECRUITING | PHASE1

16 participants

Modulation of the Bone Immune Microenvironment Following Cabozantinib Treatment of Bone Metastatic Clear Cell Renal Cell Carcinoma: Proof of Concept Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-02-12
Completion:: 2027-04-07

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07187687 | RECRUITING | NA

750 participants

TrIal of Early Minimally Invasive Catheter Evacuation With Thrombolysis in IntraCerebral Hemorrhage

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-10-24
Completion:: 2027-09-01

Conditions

Intracerebral Hemorrhage

Interventions

PROCEDURE

No Results Yet

NCT07178145 | RECRUITING | PHASE4

192 participants

Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-11-20
Completion:: 2029-09-30

Conditions

Heart Failure Preserved Ejection Fraction
Epicardial Adipose Tissue

Interventions

DRUG

No Results Yet

NCT07177261 | RECRUITING | NA

100 participants

Inter-Brain Synchrony in Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-11-11
Completion:: 2027-08-01

Conditions

Schizophrenia Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07174869 | COMPLETED

32 participants

A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-09-19
Completion:: 2026-07-09

Conditions

Mild Cognitive Impairment (MCI)
Mild Alzheimer Disease

No Results Yet

NCT07174557 | RECRUITING | NA

320 participants

Remote Evaluation and Alerting for Collaborative Health (REACH) in Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-05-20
Completion:: 2028-04-01

Conditions

Depression
Major Depressive Disorder

Interventions

OTHER

No Results Yet

NCT07166601 | RECRUITING | PHASE1

77 participants

M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-10-10
Completion:: 2029-02-23

Conditions

Advanced Solid Tumor

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT07161258 | RECRUITING | PHASE2

12 participants

A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-10-06
Completion:: 2027-06-08

Conditions

Relapsing Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT07161037 | ACTIVE_NOT_RECRUITING | PHASE2

26 participants

Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-11-19
Completion:: 2027-07-22

Conditions

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Interventions

DRUG

No Results Yet