Clinical Trials

NCT07041099 | RECRUITING | PHASE1

36 participants

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-10-01
Completion:: 2028-03-15

Conditions

Sjögren
Sjogren Disease
Sjogren's Syndrome

Interventions

DRUG

No Results Yet

NCT07038356 | RECRUITING | PHASE3

536 participants

Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-12-08
Completion:: 2027-04-30

Conditions

Acute Decompensated Heart Failure (ADHF)

Interventions

DRUG

No Results Yet

NCT07037940 | COMPLETED | NA

41 participants

Physician Response Evaluation With Contextual Insights vs. Standard Engines - Artificial Intelligence RAG vs LLM Clinical Decision Support

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-07-03
Completion:: 2025-12-30

Conditions

Large Language Models

Interventions

OTHER

No Results Yet

NCT07032038 | NOT_YET_RECRUITING | PHASE1/PHASE2

20 participants

First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-11-30
Completion:: 2028-07-31

Conditions

Sensorineural Hearing Loss
Presbyacusis
Auditory Neuropathy

Interventions

DRUG
DEVICE

No Results Yet

NCT07030972 | COMPLETED | NA

42 participants

Effect of Deep Friction Massage on Pain, Function, Kinesiophobia, and Quality of Life in Bicipital Tendinitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2024-12-20
Completion:: 2026-05-20

Conditions

Bicipital Tendonitis

Interventions

OTHER

No Results Yet

NCT07021313 | ACTIVE_NOT_RECRUITING | NA

378 participants

Deliver mOre aPplications for More Durable Pulmonary Vein IsOlation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-06-30
Completion:: 2027-06-30

Conditions

Atrial Fibrillation

Interventions

DEVICE

No Results Yet

NCT07014293 | RECRUITING | NA

254 participants

Increasing Resiliency Among Early Post-Treatment Lymphoma Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-08-31
Completion:: 2030-07-01

Conditions

Lymphoma

Interventions

OTHER

No Results Yet

NCT07013435 | NOT_YET_RECRUITING | NA

254 participants

A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-08-31
Completion:: 2029-09-30

Conditions

Lymphoma

Interventions

OTHER

No Results Yet

NCT07011732 | RECRUITING | PHASE3

426 participants

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-07-10
Completion:: 2028-11-24

Conditions

Alzheimer Disease

Interventions

DRUG

No Results Yet

NCT07010627 | COMPLETED | NA

60 participants

Chronic Pain Treatment Whith Auricular Laserpuncture

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-05-20
Completion:: 2025-12-18

Conditions

Chronic Knee Pain
Chronic Shoulder Pain
Chronic Low Back Pain

Interventions

PROCEDURE

No Results Yet

NCT07010159 | RECRUITING | PHASE2/PHASE3

325 participants

Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-07-25
Completion:: 2027-12-31

Conditions

Pericarditis
Pericarditis Acute
Recurrent Pericarditis

Interventions

DRUG

No Results Yet

NCT07000123 | ACTIVE_NOT_RECRUITING | PHASE3

3103 participants

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-05-28
Completion:: 2027-01-11

Conditions

Cardiovascular Disease

Interventions

DRUG

No Results Yet

NCT06999928 | RECRUITING | NA

200 participants

Enhanced Mentor Mother Strategy for Pregnant and Postpartum Women Living With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-07-10
Completion:: 2026-10-12

Conditions

Hiv
Transmission Vertical
Viremia
Adherence, Treatment
Stigmatization
Socioeconomic Adversity
Health Care Utilization
Health Care Acceptability
Peer Group
Mothers

Interventions

BEHAVIORAL

No Results Yet

NCT06990490 | COMPLETED

40 participants

Application of Lateral Position Digestive Endoscopy-Guided Endotracheal Intubation in Anesthesia for Endoscopic Diagnosis and Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-02-01
Completion:: 2025-03-31

Conditions

Endotracheal Intubation
Gastrointestinal Endoscopy
Airway Management
Lateral Position

No Results Yet

NCT06989112 | RECRUITING | PHASE3

600 participants

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-03-27
Completion:: 2029-01-19

Conditions

Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT06986070 | RECRUITING | PHASE1

18 participants

Investigation of Small Mobile Stem Cells (SMS Cells) in Participants With Chronic Obstructive Pulmonary Disease (COPD).

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-06-13
Completion:: 2026-12-31

Conditions

Chronic Obstructive Lung Disease

Interventions

BIOLOGICAL

No Results Yet

NCT06979453 | RECRUITING | PHASE3

366 participants

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-12-03
Completion:: 2029-10-12

Conditions

Plaque Psoriasis

Interventions

DRUG
OTHER

No Results Yet

NCT06965413 | ACTIVE_NOT_RECRUITING | PHASE2

285 participants

A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-05-05
Completion:: 2026-08-22

Conditions

Obesity
Overweight
Overweight With One Weight Related Comorbidity

Interventions

DRUG

No Results Yet

NCT06961591 | RECRUITING | NA

114 participants

Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual Disabilities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-05-19
Completion:: 2028-12-31

Conditions

Intellectual Disability
Overweight and Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06960603 | ACTIVE_NOT_RECRUITING | NA

60 participants

Pulp Inflammatory Markers and Outcome of Pulpotomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2024-10-07
Completion:: 2025-12-31

Conditions

Pulpitis in Permanent Teeth
Dental Caries Extending to Pulp

Interventions

OTHER

No Results Yet

NCT06960590 | COMPLETED | NA

300 participants

Determining the Minimal Effective Dose of Static Stretching for Increasing Range of Motion in Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-03-25
Completion:: 2025-08-05

Conditions

Static Stretching

Interventions

OTHER

No Results Yet

NCT06952647 | COMPLETED

197 participants

Hematological Markers in Idiopathic Carpal Tunnel Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-04-01
Completion:: 2026-04-01

Conditions

Carpal Tunnel Syndrome (CTS)
Biomarkers / Blood

No Results Yet

NCT06940323 | RECRUITING

250 participants

Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2017-03-21
Completion:: 2030-06-30

Conditions

Multiple Sclerosis
Clinically Isolated Syndrome
NMOSD
Myasthenia Gravis

No Results Yet

NCT06939751 | RECRUITING

250 participants

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-10-28
Completion:: 2031-01-01

Conditions

Cardiac Failure
Graft Rejection

No Results Yet

NCT06930131 | RECRUITING | NA

18 participants

Effect of Anomia Rehabilitation Combined With Metacognitive Training in Patients With Chronic Vascular Aphasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-02-21
Completion:: 2026-08-31

Conditions

Aphasia
Stroke

Interventions

BEHAVIORAL

No Results Yet

NCT06921213 | RECRUITING | PHASE2

90 participants

Comprehensive Ambulatory Antibiotics for the Treatment of Congenital Syphilis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-05-04
Completion:: 2027-03-31

Conditions

Syphilis, Congenital

Interventions

DRUG

No Results Yet

NCT06920030 | RECRUITING | NA

22 participants

Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular Lead

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-04-09
Completion:: 2027-04-30

Conditions

Idiopathic Cardiomyopathy
Left Ventricular (LV) Systolic Dysfunction
Non-ischemic Cardiomyopathy

Interventions

DEVICE

No Results Yet

NCT06918002 | RECRUITING | PHASE3

824 participants

Elranatamab/Lenalidomide Consolidation and/or Elranatamab Maintenance Versus Standard of Care After D-VRd Induction in Transplant-eligible NDMM Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-07-09
Completion:: 2036-05-31

Conditions

Multiple Myeloma, Newly Diagnosed

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06915038 | RECRUITING | NA

120 participants

ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-06-11
Completion:: 2028-12-31

Conditions

Squamous Cell Carcinoma of Oropharynx
HPV Positive Cancer
Throat Cancer
Tonsil Cancer

Interventions

DIAGNOSTIC_TEST
RADIATION

No Results Yet

NCT06911112 | RECRUITING | PHASE3

200 participants

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-03-31
Completion:: 2027-07-31

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT06908096 | RECRUITING | PHASE1

750 participants

Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-05-29
Completion:: 2027-10-01

Conditions

EBV
Epstein-Barr Virus Infection
Infectious Mononucleosis
Mono

Interventions

BIOLOGICAL

No Results Yet

NCT06904183 | RECRUITING | PHASE2

320 participants

Lenvatinib, Sintilimab, and DEB-TACE With/Without HAIC for HCC >7 cm With PVTT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-04-01
Completion:: 2029-03-31

Conditions

Hepatocellular Carcinoma Non-resectable

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06899152 | RECRUITING | NA

40 participants

HepQuant: Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-07-16
Completion:: 2031-07-31

Conditions

Liver Cancer
Hepatocellular Carcinoma
Hepatocellular Cancer
Cholangiocarcinoma
Liver Metastases

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT06898138 | NOT_YET_RECRUITING | NA

8 participants

Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-11-01
Completion:: 2029-02-15

Conditions

Epilepsy

Interventions

DEVICE

No Results Yet

NCT06897098 | COMPLETED | PHASE1

11 participants

Regeneration of Knee and Ankle Cartilage From Autologous Cartilage Mini-grafts (From the Patient's Own Cells)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-06-10
Completion:: 2025-04-02

Conditions

Cartilage Repair

Interventions

BIOLOGICAL

No Results Yet

NCT06891209 | RECRUITING

300 participants

Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-01-15
Completion:: 2027-01-31

Conditions

Bladder Carcinoma

Interventions

OTHER

No Results Yet

NCT06887582 | COMPLETED | NA

44 participants

Crestal Sinus Lifting in Periodontally-Compromised Patients Utilizing Autologous Dentin Graft

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-03-21
Completion:: 2026-06-30

Conditions

Maxillary Sinus Disease
Alveolar Bone Loss

Interventions

PROCEDURE

No Results Yet

NCT06885697 | RECRUITING | PHASE1

100 participants

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-07-08
Completion:: 2034-06-01

Conditions

Mesothelioma
Neoplasms
Stomach Neoplasms
Pancreatic Neoplasms
Ovarian Neoplasms
Lung Neoplasms
Thymus Neoplasms
Colonic Neoplasms

Interventions

DEVICE
BIOLOGICAL
DRUG

No Results Yet

NCT06880523 | RECRUITING | PHASE2

140 participants

STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-10-21
Completion:: 2028-01-31

Conditions

Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT06878976 | ENROLLING_BY_INVITATION | PHASE3

236 participants

A Study to Assess the Long-term Safety and Efficacy of Solriamfetol in Subjects With Binge Eating Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-02-20
Completion:: 2027-12-31

Conditions

Binge-Eating Disorder

Interventions

DRUG

No Results Yet