Clinical Trials

NCT04859335 | RECRUITING | NA

50 participants

Evolution of Balance and Vestibular Function in Patients Treated With Gammaknife Radiosurgery for Vestibular Schwannoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-05-21

Completion:

2028-12-01

Conditions

• Vestibular Schwannoma

Interventions

• RADIATION

No Results Yet

NCT04858334 | RECRUITING | PHASE2

152 participants

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-06-22

Completion:

2027-10-31

Conditions

• Pancreatic Acinar Cell Carcinoma
• Pancreatic Adenosquamous Carcinoma
• Pancreatic Squamous Cell Carcinoma
• Resectable Pancreatic Acinar Cell Carcinoma
• Resectable Pancreatic Adenocarcinoma
• Resectable Pancreatic Adenosquamous Carcinoma
• Resectable Pancreatic Carcinoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04845347 | COMPLETED | NA

95 participants

A Wearable Morning Light Treatment for Postpartum Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-06-23

Completion:

2025-07-23

Conditions

• Post Partum Depression

Interventions

• DEVICE

Results Available

NCT04840797 | RECRUITING

1400 participants

HeartStart HS1 Defibrillator* Event Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2021-02-25

Completion:

2030-12-31

Conditions

• Sudden Cardiac Arrest

Interventions

• DEVICE

No Results Yet

NCT04837716 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Ensartinib, Carboplatin, Pemetrexed and Bevacizumab for the Treatment of Stage IIIC or IV or Recurrent ALK-Positive Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-18

Completion:

2027-09-23

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04827719 | COMPLETED | PHASE2

38 participants

BST-236 as a Single Agent in Adults With Relapsed or Refractory AML or HR-MDS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-05-01

Completion:

2025-01-13

Conditions

• Myelodysplastic Syndromes
• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT04822636 | COMPLETED | NA

33 participants

Family Mental Health Family Navigator Project (FMHN)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-06-06

Completion:

2025-11-01

Conditions

• Mental Health

Interventions

• BEHAVIORAL

No Results Yet

NCT04790474 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

Ixazomib-pomalidomide-dexamethasone as Second or Third-line Combination Treatment for Patients With Relapsed and Refractory Multiple Myeloma Previously Treated With Daratumumab, Lenalidomide and Bortezomib

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-25

Completion:

2027-09-01

Conditions

• Multiple Myeloma in Relapse
• Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT04769193 | COMPLETED | NA

35 participants

A Clinical Trial Evaluating the Efficacy of a Skin Cream in Improving Facial Appearance and Skin Elasticity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-01-27

Completion:

2022-04-15

Conditions

• Atrophy, Hemifacial
• Elastosis
• Photoaging

Interventions

• OTHER

No Results Yet

NCT04760626 | COMPLETED | PHASE3

1085 participants

A Research Study to Compare a New Weekly Insulin, Insulin Icodec Used With DoseGuide App, and Daily Insulins in People With Type 2 Diabetes Who Have Not Used Insulin Before

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-01

Completion:

2022-08-12

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

Results Available

NCT04756453 | COMPLETED | NA

280 participants

The Effect of Clip-traction on ESD Resection Time.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-02-15

Completion:

2026-04-30

Conditions

• Adenoma Colon

Interventions

• DEVICE

No Results Yet

NCT04739761 | ACTIVE_NOT_RECRUITING | PHASE3

506 participants

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-06-22

Completion:

2024-02-08

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT04729907 | COMPLETED | PHASE3

115 participants

A Study to Learn About the Long-Term Safety of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Took Part in an Earlier Nusinersen Trial (ONWARD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-04-19

Completion:

2026-07-30

Conditions

• Muscular Atrophy, Spinal

Interventions

• DRUG

No Results Yet

NCT04708054 | RECRUITING | PHASE2/PHASE3

324 participants

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-10-21

Completion:

2027-12-31

Conditions

• Acute Myeloid Leukemia
• Chronic Myelomonocytic Leukemia
• Myelodysplastic Syndrome

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04706923 | COMPLETED | PHASE2

53 participants

A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-08-16

Completion:

2025-05-15

Conditions

• Adenovirus Infections
• Cytomegalovirus Infection

Interventions

• DRUG

No Results Yet

NCT04685135 | ACTIVE_NOT_RECRUITING | PHASE3

453 participants

Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-02-23

Completion:

2023-12-30

Conditions

• Metastatic Non Small Cell Lung Cancer
• Advanced Non Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT04684108 | ACTIVE_NOT_RECRUITING | PHASE1

61 participants

SG301 Safety Study in Subjects With Relapsed or Refractory Multiple Myeloma and Other Hematological Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-11-04

Completion:

2024-06-30

Conditions

• Relapsed or Refractory Multiple Myeloma
• Hematological Malignancy

Interventions

• DRUG

No Results Yet

NCT04675710 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Pembrolizumab, Dabrafenib, and Trametinib Before Surgery for the Treatment of BRAF-Mutated Anaplastic Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-06-24

Completion:

2026-10-30

Conditions

• Thyroid Gland Anaplastic Carcinoma
• Thyroid Gland Squamous Cell Carcinoma

Interventions

• PROCEDURE
• DRUG
• RADIATION
• BIOLOGICAL
• OTHER

No Results Yet

NCT04627922 | COMPLETED | PHASE4

41 participants

N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-08-25

Completion:

2025-06-30

Conditions

• Cannabis Use
• Tobacco Use Disorder
• Drug Use Disorder

Interventions

• DRUG
• OTHER
• BEHAVIORAL

Results Available

NCT04611087 | RECRUITING

39 participants

Self-monitoring Focus Groups With Vibrant Lives Pasadena Participants

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2018-07-03

Completion:

2027-04-30

Conditions

• Obesity-Related Malignant Neoplasm

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT04594772 | ACTIVE_NOT_RECRUITING | PHASE2

32 participants

Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-17

Completion:

2025-06-13

Conditions

• Pancreas Cancer

Interventions

• DRUG
• RADIATION
• PROCEDURE

No Results Yet

NCT04588662 | ACTIVE_NOT_RECRUITING

122 participants

A Prospective Natural History Study in Uveal Melanoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2021-05-06

Completion:

2027-03-31

Conditions

• Uveal Melanoma

No Results Yet

NCT04565431 | COMPLETED

7 participants

Examining Effects of Tysabri on Cognitive Fatigue Using fMRI

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-19

Completion:

2025-12-15

Conditions

• Multiple Sclerosis, Relapsing-Remitting

Interventions

• DRUG

No Results Yet

NCT04565041 | ACTIVE_NOT_RECRUITING | NA

100 participants

Social Support and Enhanced Fear Extinction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-02-01

Completion:

2026-09-01

Conditions

• Fear
• Anxiety

Interventions

• BEHAVIORAL

No Results Yet

NCT04564976 | ACTIVE_NOT_RECRUITING | NA

100 participants

Social Support and Reduced Fear Acquisition

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-02-09

Completion:

2026-09-01

Conditions

• Fear
• Anxiety

Interventions

• BEHAVIORAL

No Results Yet

NCT04560660 | COMPLETED | PHASE2

73 participants

Ketamine-enhanced Prolonged Exposure Therapy in PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-09

Completion:

2025-07-01

Conditions

• PTSD

Interventions

• DRUG

Results Available

NCT04556890 | RECRUITING | NA

54 participants

Pain and Major Depressive Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-03-01

Completion:

2027-12-31

Conditions

• Major Depressive Disorder
• Chronic Pain

Interventions

• DEVICE

No Results Yet

NCT04550494 | ACTIVE_NOT_RECRUITING | PHASE2

29 participants

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-04-26

Completion:

2026-07-10

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Castration-Resistant Prostate Carcinoma
• Clinical Stage III Gastric Cancer AJCC v8
• Clinical Stage IV Gastric Cancer AJCC v8
• HER2-Positive Breast Carcinoma
• Locally Advanced Breast Carcinoma
• Locally Advanced Gastric Carcinoma
• Locally Advanced Malignant Solid Neoplasm
• Locally Advanced Ovarian Carcinoma
• Locally Advanced Pancreatic Carcinoma
• Locally Advanced Prostate Carcinoma
• Metastatic Breast Carcinoma
• Metastatic Gastric Carcinoma
• Metastatic Malignant Solid Neoplasm
• Metastatic Ovarian Carcinoma
• Metastatic Pancreatic Carcinoma
• Metastatic Prostate Carcinoma
• Platinum-Sensitive Ovarian Carcinoma
• Recurrent Breast Carcinoma
• Recurrent Gastric Carcinoma
• Recurrent Ovarian Carcinoma
• Recurrent Pancreatic Carcinoma
• Recurrent Prostate Carcinoma
• Stage II Pancreatic Cancer AJCC v8
• Stage III Ovarian Cancer AJCC v8
• Stage III Pancreatic Cancer AJCC v8
• Stage III Prostate Cancer AJCC v8
• Stage IV Ovarian Cancer AJCC v8
• Stage IV Pancreatic Cancer AJCC v8
• Stage IV Prostate Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04537741 | ACTIVE_NOT_RECRUITING | NA

300 participants

Coronary CT Angiography in Non ST-elevation Myocardial Infarction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-10-24

Completion:

2024-05-31

Conditions

• Non-ST Elevated Myocardial Infarction

Interventions

• PROCEDURE

No Results Yet

NCT04526938 | SUSPENDED | NA

200 participants

Physician-modified Endovascular Graft for Repair of Complex Thoracoabdominal and Abdominal Aortic Aneurysms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-09-20

Completion:

2028-09-30

Conditions

• Juxtarenal Aortic Aneurysm
• Suprarenal Aortic Aneurysm
• Thoracoabdominal Aortic Aneurysm

Interventions

• DEVICE

No Results Yet

NCT04526782 | ACTIVE_NOT_RECRUITING | PHASE2

119 participants

ENCOrafenib With Binimetinib in bRAF NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-01-19

Completion:

2025-07-16

Conditions

• Non Small Cell Lung Cancer
• BRAF V600E

Interventions

• DRUG

No Results Yet

NCT04526678 | COMPLETED | NA

23 participants

Oslo Footballplayers Iron Supplementation and Training (FIT) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-08-19

Completion:

2020-12-03

Conditions

• Athletes
• Iron
• Endurance Performance
• Hemoglobin
• Intestinal Health
• Microbiota

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04517266 | RECRUITING | NA

214 participants

Evaluating Omitting of Internal Mammary Irradiation Among Early Stage Intermediate Risk (N1) Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-01

Completion:

2027-10-30

Conditions

• Breast Cancer

Interventions

• RADIATION

No Results Yet

NCT04470050 | COMPLETED | PHASE1/PHASE2

225 participants

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-06-09

Completion:

2021-02-18

Conditions

• Opioid Withdrawal

Interventions

• DRUG

Results Available

NCT04462302 | ACTIVE_NOT_RECRUITING | NA

456 participants

An Internet-based Program to Help Cancer Survivors Manage Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-05-13

Completion:

2027-05-31

Conditions

• Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04448977 | COMPLETED

24 participants

Examining Effects of Ocrevus on Cognitive Fatigue Using fMRI

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2021-05-06

Completion:

2025-10-15

Conditions

• Multiple Sclerosis, Relapsing-Remitting

Interventions

• DRUG

No Results Yet

NCT04443829 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Immunotherapy Using CAR T-cells to Target CD19 for Relapsed/Refractory CD19+ Primary CNS Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-23

Completion:

2024-12-30

Conditions

• Primary CNS Lymphoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04422652 | ACTIVE_NOT_RECRUITING | PHASE2

201 participants

Combination of Novel Therapies for CKD Comorbid Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-09-24

Completion:

2026-09-01

Conditions

• Chronic Kidney Diseases
• Major Depressive Disorder
• End Stage Kidney Disease (ESRD)

Interventions

• DRUG
• BEHAVIORAL
• OTHER

No Results Yet

NCT04417660 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-12-26

Completion:

2026-12-31

Conditions

• Thymic Epithelial Tumor
• Recurrent Thymoma
• Thymic Cancer

Interventions

• DRUG

No Results Yet

NCT04368663 | RECRUITING | NA

100 participants

The Beneficial Effect of TJ-134 for Patients With Symptomatic Pneumatosis Cystoides Intestinalis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-05-01

Completion:

2026-12-31

Conditions

• Pneumatosis Cystoides Intestinalis

Interventions

• DRUG

No Results Yet