Clinical Trials

NCT04790474 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

Ixazomib-pomalidomide-dexamethasone as Second or Third-line Combination Treatment for Patients With Relapsed and Refractory Multiple Myeloma Previously Treated With Daratumumab, Lenalidomide and Bortezomib

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-25
Completion:: 2027-09-01

Conditions

Multiple Myeloma in Relapse
Refractory Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT04769193 | COMPLETED | NA

35 participants

A Clinical Trial Evaluating the Efficacy of a Skin Cream in Improving Facial Appearance and Skin Elasticity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-01-27
Completion:: 2022-04-15

Conditions

Atrophy, Hemifacial
Elastosis
Photoaging

Interventions

OTHER

No Results Yet

NCT04760626 | COMPLETED | PHASE3

1085 participants

A Research Study to Compare a New Weekly Insulin, Insulin Icodec Used With DoseGuide App, and Daily Insulins in People With Type 2 Diabetes Who Have Not Used Insulin Before

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-01
Completion:: 2022-08-12

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Results Available

NCT04756453 | COMPLETED | NA

280 participants

The Effect of Clip-traction on ESD Resection Time.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-02-15
Completion:: 2026-04-30

Conditions

Adenoma Colon

Interventions

DEVICE

No Results Yet

NCT04739761 | ACTIVE_NOT_RECRUITING | PHASE3

506 participants

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-06-22
Completion:: 2024-02-08

Conditions

Breast Cancer

Interventions

DRUG

Results Available

NCT04729907 | COMPLETED | PHASE3

115 participants

A Study to Learn About the Long-Term Safety of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Took Part in an Earlier Nusinersen Trial (ONWARD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-04-19
Completion:: 2026-07-30

Conditions

Muscular Atrophy, Spinal

Interventions

DRUG

No Results Yet

NCT04708054 | RECRUITING | PHASE2/PHASE3

324 participants

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-10-21
Completion:: 2027-12-31

Conditions

Acute Myeloid Leukemia
Chronic Myelomonocytic Leukemia
Myelodysplastic Syndrome

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04706923 | COMPLETED | PHASE2

53 participants

A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-08-16
Completion:: 2025-05-15

Conditions

Adenovirus Infections
Cytomegalovirus Infection

Interventions

DRUG

No Results Yet

NCT04685135 | ACTIVE_NOT_RECRUITING | PHASE3

453 participants

Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-02-23
Completion:: 2023-12-30

Conditions

Metastatic Non Small Cell Lung Cancer
Advanced Non Small Cell Lung Cancer

Interventions

DRUG

Results Available

NCT04684108 | ACTIVE_NOT_RECRUITING | PHASE1

61 participants

SG301 Safety Study in Subjects With Relapsed or Refractory Multiple Myeloma and Other Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-11-04
Completion:: 2024-06-30

Conditions

Relapsed or Refractory Multiple Myeloma
Hematological Malignancy

Interventions

DRUG

No Results Yet

NCT04675710 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Pembrolizumab, Dabrafenib, and Trametinib Before Surgery for the Treatment of BRAF-Mutated Anaplastic Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-06-24
Completion:: 2026-10-30

Conditions

Thyroid Gland Anaplastic Carcinoma
Thyroid Gland Squamous Cell Carcinoma

Interventions

PROCEDURE
DRUG
RADIATION
BIOLOGICAL
OTHER

No Results Yet

NCT04627922 | COMPLETED | PHASE4

41 participants

N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-08-25
Completion:: 2025-06-30

Conditions

Cannabis Use
Tobacco Use Disorder
Drug Use Disorder

Interventions

DRUG
OTHER
BEHAVIORAL

Results Available

NCT04611087 | RECRUITING

39 participants

Self-monitoring Focus Groups With Vibrant Lives Pasadena Participants

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2018-07-03
Completion:: 2027-04-30

Conditions

Obesity-Related Malignant Neoplasm

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT04594772 | ACTIVE_NOT_RECRUITING | PHASE2

32 participants

Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-17
Completion:: 2025-06-13

Conditions

Pancreas Cancer

Interventions

DRUG
RADIATION
PROCEDURE

No Results Yet

NCT04588662 | ACTIVE_NOT_RECRUITING

122 participants

A Prospective Natural History Study in Uveal Melanoma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-05-06
Completion:: 2027-03-31

Conditions

Uveal Melanoma

No Results Yet

NCT04565431 | COMPLETED

7 participants

Examining Effects of Tysabri on Cognitive Fatigue Using fMRI

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-19
Completion:: 2025-12-15

Conditions

Multiple Sclerosis, Relapsing-Remitting

Interventions

DRUG

No Results Yet

NCT04565041 | ACTIVE_NOT_RECRUITING | NA

100 participants

Social Support and Enhanced Fear Extinction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-02-01
Completion:: 2026-09-01

Conditions

Fear
Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT04564976 | ACTIVE_NOT_RECRUITING | NA

100 participants

Social Support and Reduced Fear Acquisition

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-02-09
Completion:: 2026-09-01

Conditions

Fear
Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT04560660 | COMPLETED | PHASE2

73 participants

Ketamine-enhanced Prolonged Exposure Therapy in PTSD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-09
Completion:: 2025-07-01

Conditions

PTSD

Interventions

DRUG

Results Available

NCT04556890 | RECRUITING | NA

54 participants

Pain and Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-03-01
Completion:: 2027-12-31

Conditions

Major Depressive Disorder
Chronic Pain

Interventions

DEVICE

No Results Yet

NCT04550494 | ACTIVE_NOT_RECRUITING | PHASE2

29 participants

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-04-26
Completion:: 2026-07-10

Conditions

Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Castration-Resistant Prostate Carcinoma
Clinical Stage III Gastric Cancer AJCC v8
Clinical Stage IV Gastric Cancer AJCC v8
HER2-Positive Breast Carcinoma
Locally Advanced Breast Carcinoma
Locally Advanced Gastric Carcinoma
Locally Advanced Malignant Solid Neoplasm
Locally Advanced Ovarian Carcinoma
Locally Advanced Pancreatic Carcinoma
Locally Advanced Prostate Carcinoma
Metastatic Breast Carcinoma
Metastatic Gastric Carcinoma
Metastatic Malignant Solid Neoplasm
Metastatic Ovarian Carcinoma
Metastatic Pancreatic Carcinoma
Metastatic Prostate Carcinoma
Platinum-Sensitive Ovarian Carcinoma
Recurrent Breast Carcinoma
Recurrent Gastric Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Pancreatic Carcinoma
Recurrent Prostate Carcinoma
Stage II Pancreatic Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage III Pancreatic Cancer AJCC v8
Stage III Prostate Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8
Stage IV Prostate Cancer AJCC v8

Interventions

PROCEDURE
DRUG

No Results Yet

NCT04537741 | ACTIVE_NOT_RECRUITING | NA

300 participants

Coronary CT Angiography in Non ST-elevation Myocardial Infarction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-10-24
Completion:: 2024-05-31

Conditions

Non-ST Elevated Myocardial Infarction

Interventions

PROCEDURE

No Results Yet

NCT04526938 | SUSPENDED | NA

200 participants

Physician-modified Endovascular Graft for Repair of Complex Thoracoabdominal and Abdominal Aortic Aneurysms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-09-20
Completion:: 2028-09-30

Conditions

Juxtarenal Aortic Aneurysm
Suprarenal Aortic Aneurysm
Thoracoabdominal Aortic Aneurysm

Interventions

DEVICE

No Results Yet

NCT04526782 | ACTIVE_NOT_RECRUITING | PHASE2

119 participants

ENCOrafenib With Binimetinib in bRAF NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-01-19
Completion:: 2025-07-16

Conditions

Non Small Cell Lung Cancer
BRAF V600E

Interventions

DRUG

No Results Yet

NCT04526678 | COMPLETED | NA

23 participants

Oslo Footballplayers Iron Supplementation and Training (FIT) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-08-19
Completion:: 2020-12-03

Conditions

Athletes
Iron
Endurance Performance
Hemoglobin
Intestinal Health
Microbiota

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04517266 | RECRUITING | NA

214 participants

Evaluating Omitting of Internal Mammary Irradiation Among Early Stage Intermediate Risk (N1) Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-01
Completion:: 2027-10-30

Conditions

Breast Cancer

Interventions

RADIATION

No Results Yet

NCT04470050 | COMPLETED | PHASE1/PHASE2

225 participants

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-06-09
Completion:: 2021-02-18

Conditions

Opioid Withdrawal

Interventions

DRUG

Results Available

NCT04462302 | ACTIVE_NOT_RECRUITING | NA

456 participants

An Internet-based Program to Help Cancer Survivors Manage Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-05-13
Completion:: 2027-05-31

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT04448977 | COMPLETED

24 participants

Examining Effects of Ocrevus on Cognitive Fatigue Using fMRI

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-05-06
Completion:: 2025-10-15

Conditions

Multiple Sclerosis, Relapsing-Remitting

Interventions

DRUG

No Results Yet

NCT04443829 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Immunotherapy Using CAR T-cells to Target CD19 for Relapsed/Refractory CD19+ Primary CNS Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-23
Completion:: 2024-12-30

Conditions

Primary CNS Lymphoma

Interventions

BIOLOGICAL

No Results Yet

NCT04422652 | ACTIVE_NOT_RECRUITING | PHASE2

201 participants

Combination of Novel Therapies for CKD Comorbid Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-09-24
Completion:: 2026-09-01

Conditions

Chronic Kidney Diseases
Major Depressive Disorder
End Stage Kidney Disease (ESRD)

Interventions

DRUG
BEHAVIORAL
OTHER

No Results Yet

NCT04417660 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-12-26
Completion:: 2026-12-31

Conditions

Thymic Epithelial Tumor
Recurrent Thymoma
Thymic Cancer

Interventions

DRUG

No Results Yet

NCT04368663 | RECRUITING | NA

100 participants

The Beneficial Effect of TJ-134 for Patients With Symptomatic Pneumatosis Cystoides Intestinalis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-05-01
Completion:: 2026-12-31

Conditions

Pneumatosis Cystoides Intestinalis

Interventions

DRUG

No Results Yet

NCT04367077 | TERMINATED | PHASE2/PHASE3

206 participants

MultiStem Administration for COVID-19 Induced ARDS (MACoVIA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-04-28
Completion:: 2024-10-01

Conditions

ARDS

Interventions

BIOLOGICAL

No Results Yet

NCT04354662 | COMPLETED | PHASE2

51 participants

Toripalimab Combined With FLOT Neoadjuvant Chemotherapy in Patients With Resectable Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-05-25
Completion:: 2022-08-31

Conditions

Gastric Cancer

Interventions

DRUG

No Results Yet

NCT04336085 | COMPLETED | NA

60 participants

Comparison of Ultrasound Guided Caudal Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-04-15
Completion:: 2024-04-15

Conditions

Post Operative Pain After Pediatric Hip Surgery

Interventions

PROCEDURE

No Results Yet

NCT04302025 | RECRUITING | PHASE2

99 participants

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-11-06
Completion:: 2026-11-30

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04276883 | COMPLETED | PHASE3

380 participants

Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-02-24
Completion:: 2020-05-21

Conditions

Agitation Associated With Bipolar Disorder
Agitation,Psychomotor
Bipolar Disorder

Interventions

DRUG

Results Available

NCT04268303 | COMPLETED | PHASE3

380 participants

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-01-24
Completion:: 2020-05-06

Conditions

Agitation
Schizophrenia
Schizo Affective Disorder
Schizoaffective Disorder
Schizophreniform Disorders

Interventions

DRUG

Results Available

NCT04267848 | RECRUITING | PHASE3

1210 participants

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-06-16
Completion:: 2027-01-31

Conditions

Lung Non-Small Cell Carcinoma
Lung Non-Small Cell Squamous Carcinoma
Lung Non-Squamous Non-Small Cell Carcinoma
Stage II Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8

Interventions

PROCEDURE
DRUG
OTHER
BIOLOGICAL

No Results Yet