Clinical Trials

NCT04448977 | COMPLETED

24 participants

Examining Effects of Ocrevus on Cognitive Fatigue Using fMRI

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-05-06
Completion:: 2025-10-15

Conditions

Multiple Sclerosis, Relapsing-Remitting

Interventions

DRUG

No Results Yet

NCT04443829 | ACTIVE_NOT_RECRUITING | PHASE1

12 participants

Immunotherapy Using CAR T-cells to Target CD19 for Relapsed/Refractory CD19+ Primary CNS Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-23
Completion:: 2024-12-30

Conditions

Primary CNS Lymphoma

Interventions

BIOLOGICAL

No Results Yet

NCT04422652 | ACTIVE_NOT_RECRUITING | PHASE2

201 participants

Combination of Novel Therapies for CKD Comorbid Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-09-24
Completion:: 2026-09-01

Conditions

Chronic Kidney Diseases
Major Depressive Disorder
End Stage Kidney Disease (ESRD)

Interventions

DRUG
BEHAVIORAL
OTHER

No Results Yet

NCT04417660 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-12-26
Completion:: 2026-12-31

Conditions

Thymic Epithelial Tumor
Recurrent Thymoma
Thymic Cancer

Interventions

DRUG

No Results Yet

NCT04368663 | RECRUITING | NA

100 participants

The Beneficial Effect of TJ-134 for Patients With Symptomatic Pneumatosis Cystoides Intestinalis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-05-01
Completion:: 2026-12-31

Conditions

Pneumatosis Cystoides Intestinalis

Interventions

DRUG

No Results Yet

NCT04367077 | TERMINATED | PHASE2/PHASE3

206 participants

MultiStem Administration for COVID-19 Induced ARDS (MACoVIA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-04-28
Completion:: 2024-10-01

Conditions

ARDS

Interventions

BIOLOGICAL

No Results Yet

NCT04354662 | COMPLETED | PHASE2

51 participants

Toripalimab Combined With FLOT Neoadjuvant Chemotherapy in Patients With Resectable Gastric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-05-25
Completion:: 2022-08-31

Conditions

Gastric Cancer

Interventions

DRUG

No Results Yet

NCT04336085 | COMPLETED | NA

60 participants

Comparison of Ultrasound Guided Caudal Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-04-15
Completion:: 2024-04-15

Conditions

Post Operative Pain After Pediatric Hip Surgery

Interventions

PROCEDURE

No Results Yet

NCT04302025 | RECRUITING | PHASE2

99 participants

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-11-06
Completion:: 2026-11-30

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG
PROCEDURE

No Results Yet

NCT04276883 | COMPLETED | PHASE3

380 participants

Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-02-24
Completion:: 2020-05-21

Conditions

Agitation Associated With Bipolar Disorder
Agitation,Psychomotor
Bipolar Disorder

Interventions

DRUG

Results Available

NCT04268303 | COMPLETED | PHASE3

380 participants

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-01-24
Completion:: 2020-05-06

Conditions

Agitation
Schizophrenia
Schizo Affective Disorder
Schizoaffective Disorder
Schizophreniform Disorders

Interventions

DRUG

Results Available

NCT04251910 | COMPLETED | PHASE1/PHASE2

100 participants

Sub-Lingual Dexmedetomidine in Agitation Associated With Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-12-27
Completion:: 2022-01-24

Conditions

Agitation,Psychomotor
Dementia

Interventions

DRUG

Results Available

NCT04250857 | RECRUITING

1400 participants

HeartStart FRx Defibrillator Event Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-11-04
Completion:: 2030-12-31

Conditions

Sudden Cardiac Arrest

Interventions

DEVICE

No Results Yet

NCT04243499 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

293 participants

First-in-Human Study of ICT01 in Patients With Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-03-05
Completion:: 2027-10-31

Conditions

Solid Tumor, Adult
Hematopoietic/Lymphoid Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT04236349 | COMPLETED

30 participants

Tuberculosis Cohort in the North of Paris

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2018-05-01
Completion:: 2021-02-17

Conditions

Pulmonary Tuberculosis
Extra Pulmonary Tuberculosis

Interventions

GENETIC

No Results Yet

NCT04232553 | ACTIVE_NOT_RECRUITING | PHASE3

996 participants

A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-06-22
Completion:: 2024-11-28

Conditions

Crohn's Disease

Interventions

DRUG

Results Available

NCT04222413 | RECRUITING | PHASE1

116 participants

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-10-27
Completion:: 2027-12-31

Conditions

Advanced Solid Tumors
Metastatic Pancreatic Cancer
Pediatric Solid Tumor
Advanced Breast Cancer
Malignant Peripheral Nerve Sheath Tumor
Colorectal Neoplasms

Interventions

DRUG

No Results Yet

NCT04208529 | ENROLLING_BY_INVITATION | PHASE3

160 participants

A Long-term Follow-up Study in Participants Who Received CTX001

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-01-20
Completion:: 2039-09-30

Conditions

Beta-Thalassemia
Thalassemia
Sickle Cell Disease
Hematologic Diseases
Hemoglobinopathies
Genetic Diseases, Inborn
Sickle Cell Anemia

Interventions

BIOLOGICAL

No Results Yet

NCT04199026 | RECRUITING | NA

20 participants

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2025-02-25
Completion:: 2028-12-31

Conditions

Metastatic Sarcoma
Recurrent Sarcoma
Resectable Sarcoma

Interventions

DRUG
DEVICE
BIOLOGICAL
PROCEDURE

No Results Yet

NCT04188418 | ACTIVE_NOT_RECRUITING | PHASE3

150 participants

Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-10-23
Completion:: 2027-08-31

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

DRUG
OTHER

No Results Yet

NCT04186832 | ACTIVE_NOT_RECRUITING | NA

50 participants

Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-09-28
Completion:: 2027-12-31

Conditions

Glioma
Radiation Therapy Patient

Interventions

DEVICE
OTHER

No Results Yet

NCT04179162 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

54 participants

Bacillus Calmette-Guérin (BCG) and Gemcitabine in People With High-Grade Non-Muscle Invasive Bladder Cancer That Came Back After BCG Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-11-22
Completion:: 2027-11-30

Conditions

Non-Muscle Invasive Bladder Cancer (NMIBC)

Interventions

DRUG

No Results Yet

NCT04164082 | ACTIVE_NOT_RECRUITING | PHASE2

161 participants

Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-03-18
Completion:: 2026-12-09

Conditions

Bladder Flat Urothelial Carcinoma In Situ
Non-Muscle Invasive Bladder Urothelial Carcinoma
Stage 0a Bladder Cancer AJCC v8
Stage 0is Bladder Cancer AJCC v8
Stage I Bladder Cancer AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT04123574 | WITHDRAWN | EARLY_PHASE1

0 participants

A Pilot Study of BXCL701 in Patients With Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-10-15
Completion:: 2021-12-06

Conditions

Cancer of Pancreas
Cancer of the Pancreas
Neoplasms, Pancreatic
Pancreas Cancer
Pancreatic Cancer

Interventions

DRUG

No Results Yet

NCT04117100 | RECRUITING

500 participants

Advanced Endo-therapeutic Procedure : Registry-based Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2018-06-13
Completion:: 2025-12-31

Conditions

Zenker Diverticulum
Polyp of Colon
Colo-rectal Cancer

Interventions

PROCEDURE

No Results Yet

NCT04113109 | COMPLETED | PHASE4

46 participants

Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 2

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-11-01
Completion:: 2025-04-01

Conditions

Heart Failure

Interventions

DRUG

Results Available

NCT04098666 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

326 participants

Metformin in Alzheimer's Dementia Prevention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-03-22
Completion:: 2026-04-23

Conditions

Mild Cognitive Impairment

Interventions

DRUG

No Results Yet

NCT04092283 | ACTIVE_NOT_RECRUITING | PHASE3

660 participants

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-04-29
Completion:: 2028-12-31

Conditions

Recurrent Lung Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Unresectable Lung Non-Small Cell Carcinoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT04088396 | ACTIVE_NOT_RECRUITING | PHASE3

58 participants

A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2020-02-12
Completion:: 2026-10-31

Conditions

Systemic Juvenile Idiopathic Arthritis

Interventions

DRUG

No Results Yet

NCT04087291 | COMPLETED | NA

766 participants

Veterans Response to Dosage in Chiropractic Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-02-22
Completion:: 2025-05-20

Conditions

Low Back Pain
Patient Acceptance of Health Care
Veterans Health

Interventions

OTHER

Results Available

NCT04085315 | COMPLETED | PHASE1

23 participants

Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-11-12
Completion:: 2025-10-20

Conditions

Lung Cancer Metastatic
EGFR Gene Mutation

Interventions

DRUG

No Results Yet

NCT04069897 | COMPLETED | PHASE3

170 participants

Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-10-01
Completion:: 2025-06-13

Conditions

Migraine Disorders

Interventions

DRUG

No Results Yet

NCT04068610 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

61 participants

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-09-13
Completion:: 2022-10-10

Conditions

Metastatic Microsatellite-stable Colorectal Cancer

Interventions

DRUG

Results Available

NCT04065477 | ACTIVE_NOT_RECRUITING | NA

9 participants

Improving Time-Based Prospective Memory in TBI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-10-01
Completion:: 2023-03-31

Conditions

Traumatic Brain Injury

Interventions

BEHAVIORAL

No Results Yet

NCT04010305 | COMPLETED | PHASE1

135 participants

Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-05-22
Completion:: 2019-07-31

Conditions

Agitation
Schizophrenia

Interventions

DRUG

No Results Yet

NCT03967223 | ACTIVE_NOT_RECRUITING | PHASE2

103 participants

Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-12-31
Completion:: 2024-03-01

Conditions

Neoplasms

Interventions

DRUG

No Results Yet

NCT03927885 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

100 participants

Open Labeled Placebo in Reducing Cancer Related Fatigue in Patients With Advanced Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-03-30
Completion:: 2026-12-31

Conditions

Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm
Recurrent Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT03866382 | RECRUITING | PHASE2

314 participants

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-05-13
Completion:: 2027-02-28

Conditions

Bladder Adenocarcinoma
Bladder Clear Cell Adenocarcinoma
Bladder Mixed Adenocarcinoma
Bladder Neuroendocrine Carcinoma
Bladder Small Cell Neuroendocrine Carcinoma
Bladder Squamous Cell Carcinoma
Chromophobe Renal Cell Carcinoma
Collecting Duct Carcinoma
Invasive Bladder Giant Cell Urothelial Carcinoma
Invasive Bladder Lymphoepithelioma-Like Carcinoma
Invasive Bladder Nested Urothelial Carcinoma
Invasive Bladder Plasmacytoid Urothelial Carcinoma
Invasive Bladder Sarcomatoid Urothelial Carcinoma
Invasive Bladder Urothelial Carcinoma
Kidney Medullary Carcinoma
Large Cell Neuroendocrine Carcinoma
Malignant Testicular Leydig Cell Tumor
Malignant Testicular Sertoli Cell Tumor
Metastatic Bladder Carcinoma
Metastatic Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma
Metastatic Bladder Giant Cell Urothelial Carcinoma
Metastatic Bladder Large Cell Neuroendocrine Carcinoma
Metastatic Bladder Lipid-Rich Urothelial Carcinoma
Metastatic Bladder Micropapillary Urothelial Carcinoma
Metastatic Bladder Plasmacytoid Urothelial Carcinoma
Metastatic Bladder Sarcomatoid Urothelial Carcinoma
Metastatic Bladder Small Cell Neuroendocrine Carcinoma
Metastatic Bladder Squamous Cell Carcinoma
Metastatic Chromophobe Renal Cell Carcinoma
Metastatic Kidney Medullary Carcinoma
Metastatic Malignant Genitourinary System Neoplasm
Metastatic Papillary Renal Cell Carcinoma
Metastatic Penile Carcinoma
Metastatic Prostate Small Cell Neuroendocrine Carcinoma
Metastatic Sarcomatoid Renal Cell Carcinoma
Metastatic Urethral Carcinoma
Papillary Renal Cell Carcinoma
Sarcomatoid Renal Cell Carcinoma
Stage IV Bladder Cancer AJCC v8
Stage IV Penile Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8
Stage IV Urethral Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8
Urachal Adenocarcinoma
Urethral Clear Cell Adenocarcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT03830229 | RECRUITING

1000 participants

Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-03-13
Completion:: 2032-12-31

Conditions

Mesothelioma
Families

No Results Yet

NCT03813615 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

60 participants

Study of the Effects of Pre-surgical Aerobic Exercise on Patients With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2019-01-21
Completion:: 2027-01-31

Conditions

Preoperative Aerobic Training
Solid Tumors

Interventions

BEHAVIORAL

No Results Yet