Clinical Trials

NCT04367077 | TERMINATED | PHASE2/PHASE3

206 participants

MultiStem Administration for COVID-19 Induced ARDS (MACoVIA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-04-28

Completion:

2024-10-01

Conditions

• ARDS

Interventions

• BIOLOGICAL

No Results Yet

NCT04354662 | COMPLETED | PHASE2

51 participants

Toripalimab Combined With FLOT Neoadjuvant Chemotherapy in Patients With Resectable Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-05-25

Completion:

2022-08-31

Conditions

• Gastric Cancer

Interventions

• DRUG

No Results Yet

NCT04336085 | COMPLETED | NA

60 participants

Comparison of Ultrasound Guided Caudal Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-04-15

Completion:

2024-04-15

Conditions

• Post Operative Pain After Pediatric Hip Surgery

Interventions

• PROCEDURE

No Results Yet

NCT04302025 | RECRUITING | PHASE2

99 participants

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-11-06

Completion:

2026-11-30

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04276883 | COMPLETED | PHASE3

380 participants

Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-02-24

Completion:

2020-05-21

Conditions

• Agitation Associated With Bipolar Disorder
• Agitation,Psychomotor
• Bipolar Disorder

Interventions

• DRUG

Results Available

NCT04268303 | COMPLETED | PHASE3

380 participants

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-01-24

Completion:

2020-05-06

Conditions

• Agitation
• Schizophrenia
• Schizo Affective Disorder
• Schizoaffective Disorder
• Schizophreniform Disorders

Interventions

• DRUG

Results Available

NCT04251910 | COMPLETED | PHASE1/PHASE2

100 participants

Sub-Lingual Dexmedetomidine in Agitation Associated With Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-12-27

Completion:

2022-01-24

Conditions

• Agitation,Psychomotor
• Dementia

Interventions

• DRUG

Results Available

NCT04250857 | RECRUITING

1400 participants

HeartStart FRx Defibrillator Event Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2019-11-04

Completion:

2030-12-31

Conditions

• Sudden Cardiac Arrest

Interventions

• DEVICE

No Results Yet

NCT04243499 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

293 participants

First-in-Human Study of ICT01 in Patients With Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-03-05

Completion:

2027-10-31

Conditions

• Solid Tumor, Adult
• Hematopoietic/Lymphoid Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04236349 | COMPLETED

30 participants

Tuberculosis Cohort in the North of Paris

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2018-05-01

Completion:

2021-02-17

Conditions

• Pulmonary Tuberculosis
• Extra Pulmonary Tuberculosis

Interventions

• GENETIC

No Results Yet

NCT04232553 | ACTIVE_NOT_RECRUITING | PHASE3

996 participants

A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-06-22

Completion:

2024-11-28

Conditions

• Crohn's Disease

Interventions

• DRUG

Results Available

NCT04222413 | RECRUITING | PHASE1

116 participants

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-10-27

Completion:

2027-12-31

Conditions

• Advanced Solid Tumors
• Metastatic Pancreatic Cancer
• Pediatric Solid Tumor
• Advanced Breast Cancer
• Malignant Peripheral Nerve Sheath Tumor
• Colorectal Neoplasms

Interventions

• DRUG

No Results Yet

NCT04208529 | ENROLLING_BY_INVITATION | PHASE3

160 participants

A Long-term Follow-up Study in Participants Who Received CTX001

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-01-20

Completion:

2039-09-30

Conditions

• Beta-Thalassemia
• Thalassemia
• Sickle Cell Disease
• Hematologic Diseases
• Hemoglobinopathies
• Genetic Diseases, Inborn
• Sickle Cell Anemia

Interventions

• BIOLOGICAL

No Results Yet

NCT04199026 | RECRUITING | NA

20 participants

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2025-02-25

Completion:

2028-12-31

Conditions

• Metastatic Sarcoma
• Recurrent Sarcoma
• Resectable Sarcoma

Interventions

• DRUG
• DEVICE
• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT04188418 | ACTIVE_NOT_RECRUITING | PHASE3

150 participants

Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-10-23

Completion:

2027-08-31

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

• DRUG
• OTHER

No Results Yet

NCT04186832 | ACTIVE_NOT_RECRUITING | NA

50 participants

Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-09-28

Completion:

2027-12-31

Conditions

• Glioma
• Radiation Therapy Patient

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04179162 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

54 participants

Bacillus Calmette-Guérin (BCG) and Gemcitabine in People With High-Grade Non-Muscle Invasive Bladder Cancer That Came Back After BCG Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-11-22

Completion:

2027-11-30

Conditions

• Non-Muscle Invasive Bladder Cancer (NMIBC)

Interventions

• DRUG

No Results Yet

NCT04164082 | ACTIVE_NOT_RECRUITING | PHASE2

161 participants

Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-03-18

Completion:

2026-12-09

Conditions

• Bladder Flat Urothelial Carcinoma In Situ
• Non-Muscle Invasive Bladder Urothelial Carcinoma
• Stage 0a Bladder Cancer AJCC v8
• Stage 0is Bladder Cancer AJCC v8
• Stage I Bladder Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT04123574 | WITHDRAWN | EARLY_PHASE1

0 participants

A Pilot Study of BXCL701 in Patients With Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-10-15

Completion:

2021-12-06

Conditions

• Cancer of Pancreas
• Cancer of the Pancreas
• Neoplasms, Pancreatic
• Pancreas Cancer
• Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT04117100 | RECRUITING

500 participants

Advanced Endo-therapeutic Procedure : Registry-based Observational Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2018-06-13

Completion:

2025-12-31

Conditions

• Zenker Diverticulum
• Polyp of Colon
• Colo-rectal Cancer

Interventions

• PROCEDURE

No Results Yet

NCT04113109 | COMPLETED | PHASE4

46 participants

Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-11-01

Completion:

2025-04-01

Conditions

• Heart Failure

Interventions

• DRUG

Results Available

NCT04098666 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

326 participants

Metformin in Alzheimer's Dementia Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-03-22

Completion:

2026-04-23

Conditions

• Mild Cognitive Impairment

Interventions

• DRUG

No Results Yet

NCT04092283 | ACTIVE_NOT_RECRUITING | PHASE3

660 participants

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-04-29

Completion:

2028-12-31

Conditions

• Recurrent Lung Non-Small Cell Carcinoma
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Unresectable Lung Non-Small Cell Carcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04088396 | ACTIVE_NOT_RECRUITING | PHASE3

58 participants

A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2020-02-12

Completion:

2026-10-31

Conditions

• Systemic Juvenile Idiopathic Arthritis

Interventions

• DRUG

No Results Yet

NCT04087291 | COMPLETED | NA

766 participants

Veterans Response to Dosage in Chiropractic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-02-22

Completion:

2025-05-20

Conditions

• Low Back Pain
• Patient Acceptance of Health Care
• Veterans Health

Interventions

• OTHER

Results Available

NCT04085315 | COMPLETED | PHASE1

23 participants

Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-11-12

Completion:

2025-10-20

Conditions

• Lung Cancer Metastatic
• EGFR Gene Mutation

Interventions

• DRUG

No Results Yet

NCT04069897 | COMPLETED | PHASE3

170 participants

Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-10-01

Completion:

2025-06-13

Conditions

• Migraine Disorders

Interventions

• DRUG

No Results Yet

NCT04068610 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

61 participants

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-09-13

Completion:

2022-10-10

Conditions

• Metastatic Microsatellite-stable Colorectal Cancer

Interventions

• DRUG

Results Available

NCT04065477 | ACTIVE_NOT_RECRUITING | NA

9 participants

Improving Time-Based Prospective Memory in TBI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-10-01

Completion:

2023-03-31

Conditions

• Traumatic Brain Injury

Interventions

• BEHAVIORAL

No Results Yet

NCT04010305 | COMPLETED | PHASE1

135 participants

Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-05-22

Completion:

2019-07-31

Conditions

• Agitation
• Schizophrenia

Interventions

• DRUG

No Results Yet

NCT03967223 | ACTIVE_NOT_RECRUITING | PHASE2

103 participants

Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-12-31

Completion:

2024-03-01

Conditions

• Neoplasms

Interventions

• DRUG

No Results Yet

NCT03927885 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

100 participants

Open Labeled Placebo in Reducing Cancer Related Fatigue in Patients With Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-03-30

Completion:

2026-12-31

Conditions

• Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm
• Recurrent Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT03866382 | RECRUITING | PHASE2

314 participants

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-05-13

Completion:

2027-02-28

Conditions

• Bladder Adenocarcinoma
• Bladder Clear Cell Adenocarcinoma
• Bladder Mixed Adenocarcinoma
• Bladder Neuroendocrine Carcinoma
• Bladder Small Cell Neuroendocrine Carcinoma
• Bladder Squamous Cell Carcinoma
• Chromophobe Renal Cell Carcinoma
• Collecting Duct Carcinoma
• Invasive Bladder Giant Cell Urothelial Carcinoma
• Invasive Bladder Lymphoepithelioma-Like Carcinoma
• Invasive Bladder Nested Urothelial Carcinoma
• Invasive Bladder Plasmacytoid Urothelial Carcinoma
• Invasive Bladder Sarcomatoid Urothelial Carcinoma
• Invasive Bladder Urothelial Carcinoma
• Kidney Medullary Carcinoma
• Large Cell Neuroendocrine Carcinoma
• Malignant Testicular Leydig Cell Tumor
• Malignant Testicular Sertoli Cell Tumor
• Metastatic Bladder Carcinoma
• Metastatic Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma
• Metastatic Bladder Giant Cell Urothelial Carcinoma
• Metastatic Bladder Large Cell Neuroendocrine Carcinoma
• Metastatic Bladder Lipid-Rich Urothelial Carcinoma
• Metastatic Bladder Micropapillary Urothelial Carcinoma
• Metastatic Bladder Plasmacytoid Urothelial Carcinoma
• Metastatic Bladder Sarcomatoid Urothelial Carcinoma
• Metastatic Bladder Small Cell Neuroendocrine Carcinoma
• Metastatic Bladder Squamous Cell Carcinoma
• Metastatic Chromophobe Renal Cell Carcinoma
• Metastatic Kidney Medullary Carcinoma
• Metastatic Malignant Genitourinary System Neoplasm
• Metastatic Papillary Renal Cell Carcinoma
• Metastatic Penile Carcinoma
• Metastatic Prostate Small Cell Neuroendocrine Carcinoma
• Metastatic Sarcomatoid Renal Cell Carcinoma
• Metastatic Urethral Carcinoma
• Papillary Renal Cell Carcinoma
• Sarcomatoid Renal Cell Carcinoma
• Stage IV Bladder Cancer AJCC v8
• Stage IV Penile Cancer AJCC v8
• Stage IV Renal Cell Cancer AJCC v8
• Stage IV Urethral Cancer AJCC v8
• Stage IVB Prostate Cancer AJCC v8
• Urachal Adenocarcinoma
• Urethral Clear Cell Adenocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT03830229 | RECRUITING

1000 participants

Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2019-03-13

Completion:

2032-12-31

Conditions

• Mesothelioma
• Families

No Results Yet

NCT03813615 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

60 participants

Study of the Effects of Pre-surgical Aerobic Exercise on Patients With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-01-21

Completion:

2027-01-31

Conditions

• Preoperative Aerobic Training
• Solid Tumors

Interventions

• BEHAVIORAL

No Results Yet

NCT03771430 | COMPLETED | NA

282 participants

A Multidisciplinary Intervention in Total Knee Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-08-28

Completion:

2025-04-30

Conditions

• Osteoarthritis; Primary
• Degenerative Joint Disease of Knee

Interventions

• BEHAVIORAL
• PROCEDURE

No Results Yet

NCT03739372 | COMPLETED | NA

44 participants

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-11-28

Completion:

2023-12-31

Conditions

• Glioma
• Glioma of Brain
• Cancer
• Pediatric Cancer
• Pediatric Brain Tumor
• Astrocytoma
• Glioblastoma
• Hemispheric

Interventions

• OTHER

No Results Yet

NCT03708224 | ACTIVE_NOT_RECRUITING | PHASE2

55 participants

Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-03-08

Completion:

2027-07-31

Conditions

• Cancer
• Carcinoma
• Squamous Cell Carcinoma
• Head and Neck Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03656536 | TERMINATED | PHASE3

167 participants

A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2019-06-03

Completion:

2025-07-07

Conditions

• Unresectable Cholangiocarcinoma
• Metastatic Cholangiocarcinoma

Interventions

• DRUG

Results Available

NCT03654404 | COMPLETED | NA

29 participants

A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2018-09-11

Completion:

2021-03-31

Conditions

• Hematologic Malignancy
• Hematopoietic/Lymphoid Cancer
• Blood Cancer

Interventions

• BEHAVIORAL

Results Available