Clinical Trials

NCT07646444 | RECRUITING

300 participants

OPN Balloon for SAFE Recanalization of Calcified Coronary Lesions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-31

Completion:

2027-01-31

Conditions

• Coronary Arterial Disease (CAD)
• In Stent Restenosis
• Calcified Coronary Lesions

Interventions

• DEVICE

No Results Yet

NCT07641816 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2026-08-10

No Results Yet

NCT07637240 | NOT_YET_RECRUITING

60 participants

CRUISE System in Flight

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2026-09-30

Completion:

2027-07-31

Conditions

• Shock

Interventions

• DEVICE

No Results Yet

NCT07634692 | COMPLETED

257 participants

An Observational Study to Assess Nirsevimab Immunization Rates in Eligible Infants During Their First RSV Season in the Czechia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-15

Completion:

2026-06-26

Conditions

• RSV Immunization

Interventions

• BIOLOGICAL

No Results Yet

NCT07633392 | NOT_YET_RECRUITING | NA

240 participants

Effectiveness of NeoMayor in Improving Cardiovascular Health in Chilean Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-09-01

Completion:

2027-04-30

Conditions

• Cardiovascular Health Status
• Smoking Status
• Physical Activity
• Diet Quality
• Sleep Duration
• Body Mass Index
• Blood Pressure
• LDL Cholesterol
• Fasting Glucose
• Urinary Albumin-to-Creatinine Ratio

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT07630974 | RECRUITING | PHASE1/PHASE2

134 participants

A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-07-02

Completion:

2031-08-17

Conditions

• Malignant Neoplasm

Interventions

• BIOLOGICAL

No Results Yet

NCT07630870 | ACTIVE_NOT_RECRUITING | NA

14 participants

The Effects of Astaxanthin on Physiological Anti-fatigue and Sports Performance: an Integrated Study From the Application of Laboratory Human Sports Platform to Simulated Competitions

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-08-01

Completion:

2026-04-01

Conditions

• Healthy

Interventions

• OTHER

No Results Yet

NCT07630571 | COMPLETED | NA

30 participants

Efficacy of Oral HA35 for Rapid Relief of Oral Pain and Pungent Sensation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-05

Completion:

2026-06-30

Conditions

• Oral Pain
• Oral Pungent Sensation
• Capsaicin-Induced Pain
• AITC-Induced Irritation
• Oral Mucosa Discomfort

Interventions

• OTHER

No Results Yet

NCT07629960 | RECRUITING | PHASE1/PHASE2

265 participants

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-04

Completion:

2029-09-30

Conditions

• Advanced Solid Tumor
• Non-Small Cell Lung Cancer
• Colorectal Neoplasms
• Pancreatic Ductal Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT07629024 | NOT_YET_RECRUITING

200 participants

Rehabilitation Assessment of Motor Function In Cerebral Palsy Using Explainable AI

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-30

Completion:

2027-06-30

Conditions

• Cerebral Palsy Children

Interventions

• OTHER

No Results Yet

NCT07626515 | RECRUITING | PHASE1

36 participants

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Enicepatide in Generally Healthy Adult Chinese Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-07-02

Completion:

2027-05-14

Conditions

• Healthy Participants

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT07619287 | RECRUITING | PHASE1

118 participants

An Investigational Study of BG-75202 Alone and in Combination With Other Agents in Patients With Myeloid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-23

Completion:

2028-09-30

Conditions

• Myeloid Malignancy

Interventions

• DRUG

No Results Yet

NCT07616128 | RECRUITING | PHASE2

330 participants

Study of EVO756 in Adults With Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-07-29

Completion:

2027-10-31

Conditions

• Migraine

Interventions

• DRUG

No Results Yet

NCT07614984 | RECRUITING | PHASE2

750 participants

A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-30

Completion:

2027-10-12

Conditions

• Lipoprotein(a)

Interventions

• DRUG

No Results Yet

NCT07605416 | RECRUITING | PHASE2

74 participants

Testing an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2027-04-20

Completion:

2032-11-06

Conditions

• Plasma Cell Leukemia

Interventions

• PROCEDURE
• DRUG
• OTHER
• BIOLOGICAL

No Results Yet

NCT07598123 | COMPLETED | NA

80 participants

Effects of Multi-component Exercise on Physical Performance and Sleep Quality in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-05-29

Completion:

2024-12-19

Conditions

• Aging
• Sleep Quality
• Physical Performance

Interventions

• BEHAVIORAL

Results Available

NCT07597993 | RECRUITING

109 participants

BEYOND Study: A Multicentre, Prospective, Observational Study of Real-world Treatment Patterns and Outcomes of Trastuzumab Deruxtecan in Patients With HR Positive, HER2-low or Ultra-low Metastatic Breast Cancer Previously Treated With Endocrine Therapy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2026-07-12

Completion:

2029-03-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT07594236 | RECRUITING | PHASE1

15 participants

Phase 1 Study of C.001 in Retinal Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-04-07

Completion:

2028-12-31

Conditions

• Geographic Atrophy
• Stargardt Disease
• RPE-mediated Maculopathy
• Age Related Macular Degeneration

Interventions

• BIOLOGICAL

No Results Yet

NCT07594145 | NOT_YET_RECRUITING | PHASE2

57 participants

Precision T1D Platform - New Therapies for Cardio-Renal Complications

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-11-01

Completion:

2029-12-31

Conditions

• Type 1 Diabetes
• T1D Heart Failure
• Cardio-renal Vascular Function and Failure
• Diabetic Chronic Kidney Disease

Interventions

• DRUG

No Results Yet

NCT07592689 | RECRUITING | PHASE3

165 participants

A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-05-10

Completion:

2027-09-30

Conditions

• Major Depressive Disorder

Interventions

• DRUG
• OTHER

No Results Yet

NCT07592611 | NOT_YET_RECRUITING | NA

15 participants

Deep Brain Stimulation for Treatment-Resistant Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-09-01

Completion:

2029-05-30

Conditions

• Treatment Resistant Disorders

Interventions

• DEVICE

No Results Yet

NCT07590531 | RECRUITING | PHASE1/PHASE2

118 participants

AMT-116 in Combination With AK112 in Patients With Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-29

Completion:

2027-05-30

Conditions

• Advanced Non-small Cell Lung Cancer (NSCLC)

Interventions

• DRUG

No Results Yet

NCT07586397 | RECRUITING | NA

50 participants

HIPS Feasibility Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-07-20

Completion:

2027-12-01

Conditions

• Hip Pain Chronic
• Hip Pain
• Physical Medicine and Rehabilitation

Interventions

• BEHAVIORAL

No Results Yet

NCT07583641 | NOT_YET_RECRUITING | PHASE2

170 participants

A Study to Learn About How Well the Medicine Efgartigimod Works to Treat Autoimmune Encephalitis In Children 12 Years or Older and Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-07-13

Completion:

2029-01-20

Conditions

• Autoimmune Encephalitis (AE)

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT07581171 | RECRUITING | NA

80 participants

Creating Encounters Between Generations - Together Instead of Alone (GemsE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-09-01

Completion:

2026-12-01

Conditions

• Loneliness
• Mental Well-being
• Health-related Quality of Life

Interventions

• BEHAVIORAL

No Results Yet

NCT07575373 | RECRUITING | NA

75 participants

Feasibility of an Interdisciplinary Intervention to Improve Care Transitions for Hospitalized Patients With Substance Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-21

Completion:

2027-09-15

Conditions

• Substance Use Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT07574593 | RECRUITING | NA

800 participants

NORM-HF Pivotal Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-05-29

Completion:

2029-08-31

Conditions

• Heart Failure
• NYHA Class III Heart Failure
• NYHA Class II Heart Failure

Interventions

• DEVICE

No Results Yet

NCT07573462 | RECRUITING | PHASE3

2400 participants

A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-05-04

Completion:

2028-12-30

Conditions

• Pneumococcal Disease

Interventions

• BIOLOGICAL

No Results Yet

NCT07573215 | AVAILABLE

Expanded Access Program for Daraxonrasib (RMC-6236) in Previously Treated Metastatic Pancreatic Adenocarcinoma

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-08-10

Conditions

• PDAC
• PDAC - Pancreatic Ductal Adenocarcinoma
• Metastatic Pancreas Adenocarcinoma
• Pancreatic Cancer
• Pancreatic Cancer Metastatic
• Pancreatic Adenocarcinoma Metastatic
• Pancreatic Adenocarcinoma
• Pancreatic Adenosquamous Carcinoma

Interventions

• DRUG

No Results Yet

NCT07572266 | NOT_YET_RECRUITING | NA

226 participants

Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-11-30

Completion:

2031-05-31

Conditions

• Aging
• Aging Well
• Healthy Aging

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT07571486 | RECRUITING | PHASE1/PHASE2

23 participants

Therapeutic Approach of Repeated Transient Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-07-15

Completion:

2030-07-15

Conditions

• Amyotrophic Lateral Sclerosis
• Charcot Disease

Interventions

• DEVICE

No Results Yet

NCT07569640 | NOT_YET_RECRUITING | PHASE3

1672 participants

HFrEF Polypill in Sri Lanka RCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-31

Completion:

2029-04-30

Conditions

• Heart Failure With Reduced Ejection Fraction

Interventions

• OTHER
• DRUG

No Results Yet

NCT07567846 | RECRUITING | PHASE1/PHASE2

260 participants

A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-04-29

Completion:

2027-11-30

Conditions

• Advanced Prostate Cancer
• Metastatic Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT07561905 | RECRUITING | NA

60 participants

Tampon Safety-in-Use Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-05-12

Completion:

2026-08-31

Conditions

• Menstruation

Interventions

• DEVICE

No Results Yet

NCT07556549 | ACTIVE_NOT_RECRUITING

50 participants

A Study to Learn About Study Medicine Lorlatinib, as a First-line Treatment in Chinese Adults With ALK-positive a/mNSCLC

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2026-05-18

Completion:

2026-08-30

Conditions

• Non-Small Cell Lung Cancer ALK-positive

Interventions

• DRUG

No Results Yet

NCT07554352 | RECRUITING

30 participants

Early Detection of COPD Exacerbations Using Home Monitoring Device

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-05

Completion:

2027-05-31

Conditions

• COPD Exacerbation

Interventions

• DEVICE

No Results Yet

NCT07553182 | RECRUITING | PHASE3

80 participants

OLE Study With Filgotinib in JIA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-04-20

Completion:

2027-12-31

Conditions

• Juvenile Idiopathic Arthritis (JIA)

Interventions

• DRUG

No Results Yet

NCT07550088 | RECRUITING | PHASE2

17 participants

BAL/BOT/agenT-797 in pMMR CRC With Liver Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-10

Completion:

2028-09-30

Conditions

• Colorectal Cancer Metastatic

Interventions

• DRUG

No Results Yet

NCT07547540 | NOT_YET_RECRUITING | PHASE1

90 participants

A Study of LY3971297 in Participants With Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-31

Completion:

2027-11-30

Conditions

• Heart Failure
• Heart Failure, Diastolic
• Heart Failure, Systolic

Interventions

• DRUG

No Results Yet

NCT07545811 | RECRUITING | PHASE1

43 participants

Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-04-15

Completion:

2028-05-31

Conditions

• Prostate Cancer
• Metastatic Castration-resistant Prostate Cancer
• Castration-resistant Prostate Cancer

Interventions

• BIOLOGICAL

No Results Yet