Clinical Trials

NCT07020026 | RECRUITING | PHASE2

60 participants

Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-05-12

Completion:

2027-04-30

Conditions

• Parkinson's Disease

Interventions

• DRUG

No Results Yet

NCT07009899 | NOT_YET_RECRUITING | PHASE2

34 participants

BCMA Bispecific Antibody Therapy for Post-BCMA CAR T-Cell Therapy Relapse (RECLAIM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-10-01

Completion:

2028-02-01

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT07009548 | ENROLLING_BY_INVITATION | PHASE4

45 participants

CytoGam for CMV Infection or Disease in Solid Organ Transplant Recipients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-26

Completion:

2027-12-31

Conditions

• Cytomegalovirus (CMV) Infection

Interventions

• DRUG

No Results Yet

NCT07005180 | RECRUITING | PHASE2

36 participants

Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-30

Completion:

2026-12-31

Conditions

• Parkinson Disease

Interventions

• DRUG

No Results Yet

NCT07001930 | RECRUITING | PHASE1

90 participants

Effects of Cannabidiol on Stress and Nicotine Withdrawal

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-08-25

Completion:

2029-09-01

Conditions

• CBD
• Stress
• Nicotine Dependence
• Tobacco Smoking

Interventions

• DRUG

No Results Yet

NCT07001475 | COMPLETED | PHASE1

78 participants

A Study to Test How BI 3031185 is Tolerated by People With Borderline Personality Disorder or Attention-deficit/Hyperactivity Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-08-12

Completion:

2026-08-06

Conditions

• Borderline Personality Disorder
• Attention Deficit Hyperactivity Disorder

Interventions

• DRUG

No Results Yet

NCT06999902 | COMPLETED | PHASE2/PHASE3

255 participants

Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-12-11

Completion:

2026-05-14

Conditions

• Focal Seizure

Interventions

• DRUG

No Results Yet

NCT06998407 | RECRUITING | PHASE1/PHASE2

380 participants

ORION-1: Study of AVZO-023 as a Single Agent and in Combination With AVZO-021, and/or Endocrine Therapy in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-08-20

Completion:

2028-08-31

Conditions

• HR+/HER2- Breast Cancer
• HR+, HER2-, Advanced Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06993597 | RECRUITING

60 participants

Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-01

Completion:

2027-03-31

Conditions

• Glaucoma

Interventions

• DRUG
• DEVICE

No Results Yet

NCT06993480 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-07-15

Completion:

2027-07-27

Conditions

• Chronic Hepatitis B

Interventions

• DRUG

No Results Yet

NCT06990256 | ACTIVE_NOT_RECRUITING | NA

83 participants

Evaluation of Urolithin A and Fisetin on Improving Sleep and Aging Biomarkers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-16

Completion:

2026-09-30

Conditions

• Sleep Disorder
• Aging

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT06977724 | RECRUITING | PHASE1

36 participants

A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-08-26

Completion:

2029-03-31

Conditions

• Dry Eye Syndrome
• Systemic Lupus Erythematosus

Interventions

• DRUG

No Results Yet

NCT06976528 | RECRUITING | NA

160 participants

Understanding the Associations Between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse Among Emerging Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-26

Completion:

2028-07-31

Conditions

• Heavy Episodic Drinking

Interventions

• OTHER

No Results Yet

NCT06967805 | RECRUITING | PHASE2

164 participants

WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-05-05

Completion:

2027-08-31

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06963021 | RECRUITING | PHASE3

200 participants

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-05-30

Completion:

2027-07-31

Conditions

• Major Depressive Disorder

Interventions

• DRUG

No Results Yet

NCT06961370 | TERMINATED | PHASE1

27 participants

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-07-16

Completion:

2026-02-03

Conditions

• Geographic Atrophy
• Age-related Macular Degeneration

Interventions

• DRUG

No Results Yet

NCT06951906 | RECRUITING | PHASE4

54 participants

Imaging Biomarkers of FOG Response to DBS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-11-11

Completion:

2029-11-30

Conditions

• Freezing of Gait Symptoms in Parkinson's Disease
• Deep Brain Stimulation

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06934356 | RECRUITING | NA

202 participants

Subcortical Arousal in Perceptual Awareness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-13

Completion:

2030-12-31

Conditions

• Epilepsy

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT06930859 | RECRUITING

2766 participants

Non-interventional Study to Assess the Effectiveness and Safety of Ribociclib in the Adjuvant Therapy of Hormone Receptor Positive (HR+) HER2-negative Stage II and III Breast Cancer in Real Clinical Practice in Russia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-12-03

Completion:

2032-12-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06926868 | RECRUITING | PHASE2/PHASE3

600 participants

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-11

Completion:

2028-03-13

Conditions

• Breast Neoplasms

Interventions

• DRUG

No Results Yet

NCT06926621 | ENROLLING_BY_INVITATION | PHASE2

44 participants

A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-28

Completion:

2029-01-30

Conditions

• Myotonic Dystrophy Type 1 (DM1)

Interventions

• DRUG

No Results Yet

NCT06920771 | COMPLETED | PHASE3

691 participants

A Randomized, Double-Blind, Placebo-Controlled, Multi-Centre Study to Assess the Efficacy of PURETHAL Mites Mixture 50,000 AUeq/mL Subcutaneous Immunotherapy in Adult Subjects With Moderate to Severe Allergic Rhinitis/Rhinoconjunctivitis With or Without Asthma Induced by House Dust Mite (HDM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-09-09

Completion:

2026-03-30

Conditions

• House Dust Mite Allergy
• House Dust Mite Rhinitis

Interventions

• BIOLOGICAL

No Results Yet

NCT06919354 | RECRUITING | PHASE1

16 participants

A Study of GNTI-122 in Adults Recently Diagnosed With T1D

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-03

Completion:

2028-02-29

Conditions

• Type 1 Diabetes (T1D)
• Type 1 Diabetes Mellitus

Interventions

• BIOLOGICAL

No Results Yet

NCT06918990 | RECRUITING | PHASE1

25 participants

Treatment of Antibody-Mediated Rejection (ABMR) With CarBel

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-05-27

Completion:

2027-06-30

Conditions

• Kidney Transplant Rejection

Interventions

• BIOLOGICAL

No Results Yet

NCT06918925 | ACTIVE_NOT_RECRUITING | PHASE1

72 participants

First-In-Human Study to Evaluate Single and Multiple Ascending Doses of JUV-161 in Healthy Adult Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-05-14

Completion:

2026-05-30

Conditions

• Healthy Volunteer

Interventions

• DRUG

No Results Yet

NCT06895213 | ACTIVE_NOT_RECRUITING

100 participants

Evaluation of Plasma Renin Concentrations in Cardiac Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-14

Completion:

2026-12-31

Conditions

• Cardiac Surgery With Cardiopulmonary Bypass

No Results Yet

NCT06883240 | ACTIVE_NOT_RECRUITING

44 participants

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-29

Completion:

2026-11-01

Conditions

• Von Willebrand Disease, Type 3

Interventions

• DRUG

No Results Yet

NCT06880549 | RECRUITING | PHASE1

42 participants

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-25

Completion:

2027-08-03

Conditions

• Advanced Solid Tumors

Interventions

• BIOLOGICAL

No Results Yet

NCT06876051 | COMPLETED | NA

162 participants

Breastfeeding, Early Prenatal Stress Intervention, and Infant Neurodevelopment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2018-02-01

Completion:

2023-12-15

Conditions

• Stress
• Relaxation
• Breastfeeding
• Infant Behavior
• Prenatal Stress

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06869785 | ACTIVE_NOT_RECRUITING | PHASE3

196 participants

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-13

Completion:

2026-01-28

Conditions

• Relapsing Multiple Sclerosis (RMS)

Interventions

• BIOLOGICAL

No Results Yet

NCT06863961 | ACTIVE_NOT_RECRUITING | PHASE2

162 participants

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-01

Completion:

2026-07-22

Conditions

• Atopic Dermatitis

Interventions

• DRUG

No Results Yet

NCT06856720 | ENROLLING_BY_INVITATION | NA

75 participants

NMES, Exercise, and Glycemic Control in Older Adults With Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-27

Completion:

2026-10-30

Conditions

• Type 2 Diabetes Mellitus
• Hyperglycemia Due to Type 2 Diabetes Mellitus
• Aging

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT06854952 | COMPLETED | PHASE2

167 participants

A Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of TERN-601 in Adults With Overweight or Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-07

Completion:

2025-08-19

Conditions

• Overweight or Obesity

Interventions

• DRUG
• OTHER

Results Available

NCT06850649 | COMPLETED | NA

33 participants

Clinical Performance of 3D-Printed vs. Milled Endocrowns

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-05-15

Completion:

2025-05-15

Conditions

• Gross Material Loss in Endodontically Treated Upper and Lower Molars
• No Systemic Infection
• Gingival Steps Should be at Gum Level

Interventions

• OTHER

No Results Yet

NCT06845735 | RECRUITING | NA

100 participants

Absorbable vs Non-Absorbable Sutures for Hip Capsular Closure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-03-22

Completion:

2028-01-01

Conditions

• Labrum Injury of the Hip Joint
• Hip Arthroscopy
• Femoroacetabular Impingement Syndrome

Interventions

• DEVICE

No Results Yet

NCT06844006 | ENROLLING_BY_INVITATION | NA

1320 participants

Investigating the Impact of Nudging Cardiologists to Prescribe Guideline-directed Medical Therapy in Heart Failure Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-06-13

Completion:

2028-03-30

Conditions

• Heart Failure

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06843408 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

32 participants

A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-25

Completion:

2027-01-06

Conditions

• Chronic Graft-versus-host-disease

Interventions

• DRUG

No Results Yet

NCT06840834 | RECRUITING | PHASE2

38 participants

Evaluating Ivonescimab as a Potential Treatment for Pleural Mesothelioma Patients Whose Cancer Has Returned After Previous Immunotherapy and Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-30

Completion:

2026-09-30

Conditions

• Pleural Mesotheliomas

Interventions

• DRUG

No Results Yet

NCT06840015 | RECRUITING | NA

24 participants

Use of Airpod Pros as Assistive Technology

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-07-01

Completion:

2026-12-18

Conditions

• Hearing Loss, Adult-Onset
• Hearing Aids

Interventions

• DEVICE

No Results Yet

NCT06833060 | COMPLETED | NA

15 participants

Transscleral Selective Laser Trabeculoplasty Project

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-19

Completion:

2026-07-30

Conditions

• Glaucoma,Open-Angle
• Ocular Hypertension (OH)

Interventions

• DEVICE

No Results Yet