Clinical Trials

NCT06993597 | RECRUITING

60 participants

Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-09-01
Completion:: 2027-03-31

Conditions

Glaucoma

Interventions

DRUG
DEVICE

No Results Yet

NCT06993480 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-07-15
Completion:: 2027-07-27

Conditions

Chronic Hepatitis B

Interventions

DRUG

No Results Yet

NCT06990256 | ACTIVE_NOT_RECRUITING | NA

83 participants

Evaluation of Urolithin A and Fisetin on Improving Sleep and Aging Biomarkers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-09-16
Completion:: 2026-09-30

Conditions

Sleep Disorder
Aging

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06977724 | RECRUITING | PHASE1

36 participants

A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-08-26
Completion:: 2029-03-31

Conditions

Dry Eye Syndrome
Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT06976528 | RECRUITING | NA

160 participants

Understanding the Associations Between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse Among Emerging Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-09-26
Completion:: 2028-07-31

Conditions

Heavy Episodic Drinking

Interventions

OTHER

No Results Yet

NCT06970743 | ACTIVE_NOT_RECRUITING | PHASE3

153 participants

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) Inhibitors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-05-29
Completion:: 2029-11-30

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

DRUG

No Results Yet

NCT06967805 | RECRUITING | PHASE2

164 participants

WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-05-05
Completion:: 2027-08-31

Conditions

Idiopathic Pulmonary Fibrosis

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT06963021 | RECRUITING | PHASE3

200 participants

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-05-30
Completion:: 2027-07-31

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT06962800 | RECRUITING | PHASE3

180 participants

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-05-22
Completion:: 2030-01-28

Conditions

Primary Membranous Nephropathy

Interventions

DRUG

No Results Yet

NCT06961370 | TERMINATED | PHASE1

27 participants

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-07-16
Completion:: 2026-02-03

Conditions

Geographic Atrophy
Age-related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT06951906 | RECRUITING | PHASE4

54 participants

Imaging Biomarkers of FOG Response to DBS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2024-11-11
Completion:: 2029-11-30

Conditions

Freezing of Gait Symptoms in Parkinson's Disease
Deep Brain Stimulation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06943872 | RECRUITING | PHASE3

630 participants

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-06-11
Completion:: 2029-09-30

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

DRUG

No Results Yet

NCT06941844 | ACTIVE_NOT_RECRUITING | PHASE3

149 participants

A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-04-14
Completion:: 2026-05-20

Conditions

Major Depressive Disorder

Interventions

OTHER
DRUG

No Results Yet

NCT06940297 | RECRUITING | PHASE2

44 participants

Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-09-18
Completion:: 2031-08-15

Conditions

Recurrent Multiple Myeloma
Refractory Multiple Myeloma

Interventions

DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT06934356 | RECRUITING | NA

202 participants

Subcortical Arousal in Perceptual Awareness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-10-13
Completion:: 2030-12-31

Conditions

Epilepsy

Interventions

DEVICE
DIAGNOSTIC_TEST

No Results Yet

NCT06930859 | RECRUITING

2766 participants

Non-interventional Study to Assess the Effectiveness and Safety of Ribociclib in the Adjuvant Therapy of Hormone Receptor Positive (HR+) HER2-negative Stage II and III Breast Cancer in Real Clinical Practice in Russia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-12-03
Completion:: 2032-12-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT06926868 | RECRUITING | PHASE2/PHASE3

600 participants

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-09-11
Completion:: 2028-03-13

Conditions

Breast Neoplasms

Interventions

DRUG

No Results Yet

NCT06926621 | ENROLLING_BY_INVITATION | PHASE2

44 participants

A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-04-28
Completion:: 2029-01-30

Conditions

Myotonic Dystrophy Type 1 (DM1)

Interventions

DRUG

No Results Yet

NCT06920771 | COMPLETED | PHASE3

691 participants

A Randomized, Double-Blind, Placebo-Controlled, Multi-Centre Study to Assess the Efficacy of PURETHAL Mites Mixture 50,000 AUeq/mL Subcutaneous Immunotherapy in Adult Subjects With Moderate to Severe Allergic Rhinitis/Rhinoconjunctivitis With or Without Asthma Induced by House Dust Mite (HDM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2024-09-09
Completion:: 2026-03-30

Conditions

House Dust Mite Allergy
House Dust Mite Rhinitis

Interventions

BIOLOGICAL

No Results Yet

NCT06919354 | RECRUITING | PHASE1

16 participants

A Study of GNTI-122 in Adults Recently Diagnosed With T1D

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-09-03
Completion:: 2028-02-29

Conditions

Type 1 Diabetes (T1D)
Type 1 Diabetes Mellitus

Interventions

BIOLOGICAL

No Results Yet

NCT06918990 | RECRUITING | PHASE1

25 participants

Treatment of Antibody-Mediated Rejection (ABMR) With CarBel

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2026-05-27
Completion:: 2027-06-30

Conditions

Kidney Transplant Rejection

Interventions

BIOLOGICAL

No Results Yet

NCT06918925 | ACTIVE_NOT_RECRUITING | PHASE1

72 participants

First-In-Human Study to Evaluate Single and Multiple Ascending Doses of JUV-161 in Healthy Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-05-14
Completion:: 2026-05-30

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT06902480 | NOT_YET_RECRUITING | NA

24 participants

Dairy Choline Bioavailability

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2026-08-31
Completion:: 2027-04-30

Conditions

Post-menopausal Women
Post-menopausal Status

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06895213 | ACTIVE_NOT_RECRUITING

100 participants

Evaluation of Plasma Renin Concentrations in Cardiac Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-04-14
Completion:: 2026-12-31

Conditions

Cardiac Surgery With Cardiopulmonary Bypass

No Results Yet

NCT06883240 | ACTIVE_NOT_RECRUITING

44 participants

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-04-29
Completion:: 2026-11-01

Conditions

Von Willebrand Disease, Type 3

Interventions

DRUG

No Results Yet

NCT06880549 | RECRUITING | PHASE1

42 participants

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-03-25
Completion:: 2027-08-03

Conditions

Advanced Solid Tumors

Interventions

BIOLOGICAL

No Results Yet

NCT06876051 | COMPLETED | NA

162 participants

Breastfeeding, Early Prenatal Stress Intervention, and Infant Neurodevelopment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2018-02-01
Completion:: 2023-12-15

Conditions

Stress
Relaxation
Breastfeeding
Infant Behavior
Prenatal Stress

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06869785 | ACTIVE_NOT_RECRUITING | PHASE3

196 participants

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-03-13
Completion:: 2026-01-28

Conditions

Relapsing Multiple Sclerosis (RMS)

Interventions

BIOLOGICAL

No Results Yet

NCT06863961 | ACTIVE_NOT_RECRUITING | PHASE2

162 participants

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-04-01
Completion:: 2026-07-22

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06856720 | ENROLLING_BY_INVITATION | NA

75 participants

NMES, Exercise, and Glycemic Control in Older Adults With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-10-27
Completion:: 2026-10-30

Conditions

Type 2 Diabetes Mellitus
Hyperglycemia Due to Type 2 Diabetes Mellitus
Aging

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT06854952 | COMPLETED | PHASE2

167 participants

A Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of TERN-601 in Adults With Overweight or Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-03-07
Completion:: 2025-08-19

Conditions

Overweight or Obesity

Interventions

DRUG
OTHER

Results Available

NCT06850649 | COMPLETED | NA

33 participants

Clinical Performance of 3D-Printed vs. Milled Endocrowns

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-05-15
Completion:: 2025-05-15

Conditions

Gross Material Loss in Endodontically Treated Upper and Lower Molars
No Systemic Infection
Gingival Steps Should be at Gum Level

Interventions

OTHER

No Results Yet

NCT06846281 | RECRUITING | PHASE3

360 participants

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-06-23
Completion:: 2029-07-24

Conditions

Relapsing Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT06845735 | RECRUITING | NA

100 participants

Absorbable vs Non-Absorbable Sutures for Hip Capsular Closure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2024-03-22
Completion:: 2028-01-01

Conditions

Labrum Injury of the Hip Joint
Hip Arthroscopy
Femoroacetabular Impingement Syndrome

Interventions

DEVICE

No Results Yet

NCT06844006 | ENROLLING_BY_INVITATION | NA

1320 participants

Investigating the Impact of Nudging Cardiologists to Prescribe Guideline-directed Medical Therapy in Heart Failure Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2024-06-13
Completion:: 2028-03-30

Conditions

Heart Failure

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06843408 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

32 participants

A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-06-25
Completion:: 2027-01-06

Conditions

Chronic Graft-versus-host-disease

Interventions

DRUG

No Results Yet

NCT06840834 | RECRUITING | PHASE2

38 participants

Evaluating Ivonescimab as a Potential Treatment for Pleural Mesothelioma Patients Whose Cancer Has Returned After Previous Immunotherapy and Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-06-30
Completion:: 2026-09-30

Conditions

Pleural Mesotheliomas

Interventions

DRUG

No Results Yet

NCT06840015 | RECRUITING | NA

24 participants

Use of Airpod Pros as Assistive Technology

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-07-01
Completion:: 2026-12-18

Conditions

Hearing Loss, Adult-Onset
Hearing Aids

Interventions

DEVICE

No Results Yet

NCT06833060 | COMPLETED | NA

15 participants

Transscleral Selective Laser Trabeculoplasty Project

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2025-06-19
Completion:: 2026-07-30

Conditions

Glaucoma,Open-Angle
Ocular Hypertension (OH)

Interventions

DEVICE

No Results Yet

NCT06832878 | RECRUITING | PHASE4

101 participants

Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2026-06-01
Completion:: 2027-06-30

Conditions

Arthroplasty

Interventions

DRUG

No Results Yet