Clinical Trials

NCT06962800 | RECRUITING | PHASE3

180 participants

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-05-22

Completion:

2030-01-28

Conditions

• Primary Membranous Nephropathy

Interventions

• DRUG

No Results Yet

NCT06961370 | TERMINATED | PHASE1

27 participants

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-07-16

Completion:

2026-02-03

Conditions

• Geographic Atrophy
• Age-related Macular Degeneration

Interventions

• DRUG

No Results Yet

NCT06951906 | RECRUITING | PHASE4

54 participants

Imaging Biomarkers of FOG Response to DBS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-11-11

Completion:

2029-11-30

Conditions

• Freezing of Gait Symptoms in Parkinson's Disease
• Deep Brain Stimulation

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06943872 | RECRUITING | PHASE3

630 participants

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-11

Completion:

2029-09-30

Conditions

• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma

Interventions

• DRUG

No Results Yet

NCT06941844 | ACTIVE_NOT_RECRUITING | PHASE3

149 participants

A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-14

Completion:

2026-05-20

Conditions

• Major Depressive Disorder

Interventions

• OTHER
• DRUG

No Results Yet

NCT06940297 | RECRUITING | PHASE2

44 participants

Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-18

Completion:

2031-08-15

Conditions

• Recurrent Multiple Myeloma
• Refractory Multiple Myeloma

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT06934356 | RECRUITING | NA

202 participants

Subcortical Arousal in Perceptual Awareness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-13

Completion:

2030-12-31

Conditions

• Epilepsy

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT06930859 | RECRUITING

2766 participants

Non-interventional Study to Assess the Effectiveness and Safety of Ribociclib in the Adjuvant Therapy of Hormone Receptor Positive (HR+) HER2-negative Stage II and III Breast Cancer in Real Clinical Practice in Russia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-12-03

Completion:

2032-12-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06926868 | RECRUITING | PHASE2/PHASE3

600 participants

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-11

Completion:

2028-03-13

Conditions

• Breast Neoplasms

Interventions

• DRUG

No Results Yet

NCT06926621 | ENROLLING_BY_INVITATION | PHASE2

44 participants

A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-28

Completion:

2029-01-30

Conditions

• Myotonic Dystrophy Type 1 (DM1)

Interventions

• DRUG

No Results Yet

NCT06920771 | COMPLETED | PHASE3

691 participants

A Randomized, Double-Blind, Placebo-Controlled, Multi-Centre Study to Assess the Efficacy of PURETHAL Mites Mixture 50,000 AUeq/mL Subcutaneous Immunotherapy in Adult Subjects With Moderate to Severe Allergic Rhinitis/Rhinoconjunctivitis With or Without Asthma Induced by House Dust Mite (HDM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-09-09

Completion:

2026-03-30

Conditions

• House Dust Mite Allergy
• House Dust Mite Rhinitis

Interventions

• BIOLOGICAL

No Results Yet

NCT06919354 | RECRUITING | PHASE1

16 participants

A Study of GNTI-122 in Adults Recently Diagnosed With T1D

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-09-03

Completion:

2028-02-29

Conditions

• Type 1 Diabetes (T1D)
• Type 1 Diabetes Mellitus

Interventions

• BIOLOGICAL

No Results Yet

NCT06918990 | RECRUITING | PHASE1

25 participants

Treatment of Antibody-Mediated Rejection (ABMR) With CarBel

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-05-27

Completion:

2027-06-30

Conditions

• Kidney Transplant Rejection

Interventions

• BIOLOGICAL

No Results Yet

NCT06918925 | ACTIVE_NOT_RECRUITING | PHASE1

72 participants

First-In-Human Study to Evaluate Single and Multiple Ascending Doses of JUV-161 in Healthy Adult Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-05-14

Completion:

2026-05-30

Conditions

• Healthy Volunteer

Interventions

• DRUG

No Results Yet

NCT06902480 | NOT_YET_RECRUITING | NA

24 participants

Dairy Choline Bioavailability

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-31

Completion:

2027-04-30

Conditions

• Post-menopausal Women
• Post-menopausal Status

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT06895213 | ACTIVE_NOT_RECRUITING

100 participants

Evaluation of Plasma Renin Concentrations in Cardiac Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-14

Completion:

2026-12-31

Conditions

• Cardiac Surgery With Cardiopulmonary Bypass

No Results Yet

NCT06883240 | ACTIVE_NOT_RECRUITING

44 participants

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-29

Completion:

2026-11-01

Conditions

• Von Willebrand Disease, Type 3

Interventions

• DRUG

No Results Yet

NCT06880549 | RECRUITING | PHASE1

42 participants

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-25

Completion:

2027-08-03

Conditions

• Advanced Solid Tumors

Interventions

• BIOLOGICAL

No Results Yet

NCT06876051 | COMPLETED | NA

162 participants

Breastfeeding, Early Prenatal Stress Intervention, and Infant Neurodevelopment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2018-02-01

Completion:

2023-12-15

Conditions

• Stress
• Relaxation
• Breastfeeding
• Infant Behavior
• Prenatal Stress

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06869785 | ACTIVE_NOT_RECRUITING | PHASE3

196 participants

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-13

Completion:

2026-01-28

Conditions

• Relapsing Multiple Sclerosis (RMS)

Interventions

• BIOLOGICAL

No Results Yet

NCT06863961 | ACTIVE_NOT_RECRUITING | PHASE2

162 participants

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-01

Completion:

2026-07-22

Conditions

• Atopic Dermatitis

Interventions

• DRUG

No Results Yet

NCT06856720 | ENROLLING_BY_INVITATION | NA

75 participants

NMES, Exercise, and Glycemic Control in Older Adults With Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-10-27

Completion:

2026-10-30

Conditions

• Type 2 Diabetes Mellitus
• Hyperglycemia Due to Type 2 Diabetes Mellitus
• Aging

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT06854952 | COMPLETED | PHASE2

167 participants

A Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of TERN-601 in Adults With Overweight or Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-07

Completion:

2025-08-19

Conditions

• Overweight or Obesity

Interventions

• DRUG
• OTHER

Results Available

NCT06850649 | COMPLETED | NA

33 participants

Clinical Performance of 3D-Printed vs. Milled Endocrowns

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-05-15

Completion:

2025-05-15

Conditions

• Gross Material Loss in Endodontically Treated Upper and Lower Molars
• No Systemic Infection
• Gingival Steps Should be at Gum Level

Interventions

• OTHER

No Results Yet

NCT06846281 | RECRUITING | PHASE3

360 participants

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-23

Completion:

2029-07-24

Conditions

• Relapsing Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT06845735 | RECRUITING | NA

100 participants

Absorbable vs Non-Absorbable Sutures for Hip Capsular Closure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-03-22

Completion:

2028-01-01

Conditions

• Labrum Injury of the Hip Joint
• Hip Arthroscopy
• Femoroacetabular Impingement Syndrome

Interventions

• DEVICE

No Results Yet

NCT06844006 | ENROLLING_BY_INVITATION | NA

1320 participants

Investigating the Impact of Nudging Cardiologists to Prescribe Guideline-directed Medical Therapy in Heart Failure Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-06-13

Completion:

2028-03-30

Conditions

• Heart Failure

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06843408 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

32 participants

A Ph1b/2 Study of Axatilimab Monotherapy in Chinese Participants With Recurrent or Refractory cGVHD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-25

Completion:

2027-01-06

Conditions

• Chronic Graft-versus-host-disease

Interventions

• DRUG

No Results Yet

NCT06840834 | RECRUITING | PHASE2

38 participants

Evaluating Ivonescimab as a Potential Treatment for Pleural Mesothelioma Patients Whose Cancer Has Returned After Previous Immunotherapy and Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-30

Completion:

2026-09-30

Conditions

• Pleural Mesotheliomas

Interventions

• DRUG

No Results Yet

NCT06840015 | RECRUITING | NA

24 participants

Use of Airpod Pros as Assistive Technology

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-07-01

Completion:

2026-12-18

Conditions

• Hearing Loss, Adult-Onset
• Hearing Aids

Interventions

• DEVICE

No Results Yet

NCT06833060 | COMPLETED | NA

15 participants

Transscleral Selective Laser Trabeculoplasty Project

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-06-19

Completion:

2026-07-30

Conditions

• Glaucoma,Open-Angle
• Ocular Hypertension (OH)

Interventions

• DEVICE

No Results Yet

NCT06832878 | RECRUITING | PHASE4

101 participants

Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint Arthroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-06-01

Completion:

2027-06-30

Conditions

• Arthroplasty

Interventions

• DRUG

No Results Yet

NCT06830096 | RECRUITING | NA

40 participants

Role of KATP Channel Loss in Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-07

Completion:

2026-12-31

Conditions

• Obesity and Type 2 Diabetes

Interventions

• DRUG

No Results Yet

NCT06823167 | RECRUITING | PHASE1

190 participants

A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-02-26

Completion:

2028-05-31

Conditions

• Solid Malignancies
• Hematologic Malignancies

Interventions

• DRUG

No Results Yet

NCT06820359 | WITHDRAWN | NA

0 participants

Bowel Preparation in Minimally Invasive Gynecologic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-02-17

Completion:

2026-01-31

Conditions

• Gynecologic Disease

Interventions

• OTHER

No Results Yet

NCT06820281 | RECRUITING | PHASE2

44 participants

Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-07-07

Completion:

2027-12-31

Conditions

• Type 1 Diabetes Mellitus

Interventions

• DRUG

No Results Yet

NCT06809595 | ACTIVE_NOT_RECRUITING | PHASE3

245 participants

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-01-29

Completion:

2026-08-31

Conditions

• Generalized Anxiety Disorder

Interventions

• OTHER
• DRUG

No Results Yet

NCT06805994 | RECRUITING | PHASE1

175 participants

Administering NMT to Reestablish Infant Nasal Microbiome Diversity Following Intranasal Mupirocin Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-08-27

Completion:

2027-09-01

Conditions

• Staphylococcal Aureus Infection
• Microbial Colonization
• Pediatric Infection
• S. Aureus Colonization
• Microbial Transplant

Interventions

• BIOLOGICAL

No Results Yet

NCT06803680 | RECRUITING | PHASE1

90 participants

A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-03-18

Completion:

2028-04-29

Conditions

• Advanced Solid Tumor
• Metastatic Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06765980 | RECRUITING | PHASE1/PHASE2

62 participants

A Study to Evaluate KRIYA-825 (VV-14295) in Adults With Geographic Atrophy Secondary to Age-related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-05-28

Completion:

2027-12-15

Conditions

• Geographic Atrophy Secondary to Age-related Macular Degeneration

Interventions

• GENETIC

No Results Yet