Clinical Trials

NCT06161441 | ACTIVE_NOT_RECRUITING | PHASE2

195 participants

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-07-16

Completion:

2026-08-24

Conditions

• Resectable Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT06161116 | TERMINATED | PHASE2

149 participants

Efficacy and Safety of MK-6194 in Adult Participants With Systemic Lupus Erythematosus (MK-6194-006)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-27

Completion:

2025-07-30

Conditions

• Systemic Lupus Erythematosus

Interventions

• BIOLOGICAL

Results Available

NCT06154447 | COMPLETED | PHASE1

165 participants

Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-12

Completion:

2026-07-10

Conditions

• Cystic Fibrosis

Interventions

• DRUG

No Results Yet

NCT06153498 | COMPLETED | NA

36 participants

PK/PD Properties and Safety of Remazolam Besylate for Injection in ICU Patients With Impaired Renal Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-11-04

Completion:

2024-12-13

Conditions

• Mechanically Ventilated Patients

Interventions

• DRUG

No Results Yet

NCT06146634 | ACTIVE_NOT_RECRUITING | NA

8000 participants

Washington State Driving Intervention Research Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-07-15

Completion:

2027-08-31

Conditions

• Driving Behavior

Interventions

• BEHAVIORAL

No Results Yet

NCT06145412 | COMPLETED | PHASE2

4 participants

A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With Head and Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-11-16

Completion:

2026-08-04

Conditions

• Head and Neck Cancer

Interventions

• DRUG
• RADIATION

No Results Yet

NCT06136221 | ACTIVE_NOT_RECRUITING | NA

110 participants

Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-05-01

Completion:

2026-12-30

Conditions

• Cirrhosis, Liver
• End Stage Liver DIsease
• Symptoms and Signs
• Physical Inactivity
• Muscle Loss

Interventions

• BEHAVIORAL

No Results Yet

NCT06128564 | ACTIVE_NOT_RECRUITING | PHASE2

13 participants

A Gene Delivery Study to Evaluate the Safety and Expression of Delandistrogene Moxeparvovec in Participants Under the Age of Four With Duchenne Muscular Dystrophy (DMD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-11-29

Completion:

2026-03-04

Conditions

• Duchenne Muscular Dystrophy

Interventions

• GENETIC

No Results Yet

NCT06127797 | RECRUITING

1000 participants

Surveillance MRI Registry for Patients Who Had Breast Cancer With Dense Breast Tissue

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2024-01-11

Completion:

2027-08-31

Conditions

• Breast Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT06113354 | RECRUITING | NA

10 participants

EXPLORE MRace (BR): Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-04-08

Completion:

2032-12-31

Conditions

• Mitral Valve Disease

Interventions

• DEVICE

No Results Yet

NCT06105905 | COMPLETED | NA

94 participants

Latino Teen Pregnancy Prevention K23

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-09-23

Completion:

2026-06-30

Conditions

• Pregnancy in Adolescence
• Rural Health
• Hispanic or Latino

Interventions

• BEHAVIORAL

No Results Yet

NCT06105554 | RECRUITING | PHASE1/PHASE2

36 participants

Phase I/II Open Label Study of Belumosudil Mesylate Alone, and in Combination With Dexamethasone, in Patients With Relapsed/Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-01-30

Completion:

2027-08-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06093386 | COMPLETED | NA

144 participants

Promoting Intensive Transitions for Children and Youth With Medical Complexity From Pediatric to Adult Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-11-24

Completion:

2026-04-30

Conditions

• Children and Youth With Medical Complexity

Interventions

• OTHER

No Results Yet

NCT06092892 | RECRUITING | PHASE2

45 participants

IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-04-07

Completion:

2031-04-30

Conditions

• Breast Cancer
• Axillary Nodal Disease
• Female Breast Cancer
• Axilla; Breast
• Mastectomy; Lymphedema
• Tumor, Breast

Interventions

• PROCEDURE
• RADIATION

No Results Yet

NCT06092346 | RECRUITING

999 participants

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-19

Completion:

2099-01-01

Conditions

• AMPD3, OMIM*102772, AMP Deaminase Deficiency
• AK1, OMIM *103000, Adenylate Kinase Deficiency
• AMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency
• TPMT, OMIM *187680, Thoipurines, Poor Metabolism of
• IMPDH1, OMIM *146690, Retinitis Pigmentosa Type 10, Leber Congenital Amauriosis Type 11
• APRT, OMIM *102600, Adenine Phosphoribosyltransferase Deficiency
• HPRT1, OMIM *308000 Lesch-Nyhan Disease
• XDH, OMIM *607633, Xanthinuria Type 1
• SLC2A9, OMIM *606142 Hypouricemia
• SLC22A12, OMIM *607096 Hypouricemia
• PRPS1 Def, OMIM *311850, Arts Syndrome; Charcot-Marie-Tooth Disease
• PRPS1 SA, OMIM *311850 Gout, PRPS-related Phosphoribosylpyrophosphate Synthetase Superactivity
• AMPD2, OMIM *102771, Spastic Paraplegia 63; Pontocerebellar Hypoplasia
• ITPA, OMIM *147520, Inosine Triphosphatase Deficiency; Developmental and Epileptic Encephalopathy 35
• ADSL, OMIM *608222, Adenylosuccinate Lyase Deficiency
• PNP, OMIM *164050, Nucleoside Phosphorylase Deficiency
• ADA2, OMIM *607575,Sneddon Syndrome; VAIHS
• CAD, *1140120, Developmental and Epileptic Encephalopathy
• UPB1, OMIM *606673, Beta-ureidopropionase Deficiency
• DPYS, OMIM *613326, Dihydropyrimidinase Deficiency
• DPYD, OMIM *274270, Dihydropyrimidine Dehydrogenase Deficiency
• DHODH, OMIM *126064, Miller Syndrome (Postaxial Acrofacial Dysostosis)
• UMPS, OMIM *613891, Orotic Aciduria
• NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency
• UNG, OMIM *191525, Hyper-IgM Syndrome 5
• AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2
• Purine-Pyrimidine Metabolism
• Metabolic Disease

No Results Yet

NCT06091254 | RECRUITING | PHASE3

822 participants

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-12

Completion:

2028-02-07

Conditions

• Follicular Lymphoma (FL)

Interventions

• DRUG

No Results Yet

NCT06084780 | NOT_YET_RECRUITING | PHASE2

20 participants

Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-08-31

Completion:

2026-12-31

Conditions

• Secondary Malignant Neoplasm of Retroperitoneum
• Secondary Malignant Neoplasm of Peritoneum
• Pseudomyxoma Peritonei

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT06080074 | RECRUITING | PHASE2

50 participants

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2025-04-15

Completion:

2027-09-30

Conditions

• Heart Failure
• Cardiogenic Shock
• Congenital Heart Disease
• Cardiomyopathies

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06067841 | RECRUITING | PHASE1

140 participants

A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-10-18

Completion:

2029-08-24

Conditions

• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT06062329 | COMPLETED | NA

110 participants

SYMPHONY-PE Study for Treatment of Pulmonary Embolism

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-13

Completion:

2025-05-04

Conditions

• Acute Pulmonary Embolism
• Thromboembolism
• Emboli, Pulmonary
• Thrombosis
• Thrombus; Embolism
• Embolism
• Cardiovascular Diseases
• Vascular Diseases

Interventions

• DEVICE

Results Available

NCT06054347 | COMPLETED

30 participants

Evaluation by a Vineland II Scale of Long-term Development of Children With Pyridoxine Dependent Epilepsy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-29

Completion:

2025-05-21

Conditions

• Pyridoxine-Dependent Epilepsy

Interventions

• OTHER

No Results Yet

NCT06053606 | ACTIVE_NOT_RECRUITING | NA

100 participants

The Impact of Expandable Cryoballoon on Autonomic Control of the Heart

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-05-10

Completion:

2027-03-31

Conditions

• Paroxysmal Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT06046040 | ACTIVE_NOT_RECRUITING | PHASE1

30 participants

TmPSMA-02 in mCRPC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-01-31

Completion:

2027-01-31

Conditions

• Metastatic Castrate-Resistant Prostate Cancer (mCRPC)

Interventions

• DRUG

No Results Yet

NCT06033196 | RECRUITING | PHASE2

350 participants

Tocilizumab in Lung Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-02-13

Completion:

2029-01-08

Conditions

• Lung Transplant

Interventions

• DRUG

No Results Yet

NCT06029270 | RECRUITING | PHASE2

156 participants

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-07-15

Completion:

2029-04-30

Conditions

• Metastatic Nasopharyngeal Carcinoma
• Recurrent Nasopharyngeal Carcinoma
• Stage IV Nasopharyngeal Carcinoma AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT06026111 | RECRUITING | NA

30 participants

Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-02-01

Completion:

2027-12-31

Conditions

• Lung Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT06020508 | RECRUITING

36 participants

Lumoptik BRIGHTPOINT Reflectometer Device for Lumbar Epidural Placement

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2023-09-12

Completion:

2027-07-31

Conditions

• Lumbar Spine Surgery

Interventions

• DEVICE

No Results Yet

NCT06015308 | COMPLETED | PHASE2

224 participants

A Study to Investigate Vaccine Responses in Subcutaneous Amlitelimab Treated Atopic Dermatitis Participants Aged 18 Years and Older Compared With Placebo

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-10-06

Completion:

2025-10-01

Conditions

• Dermatitis Atopic

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT06003036 | COMPLETED | NA

30 participants

Accelerated Transcranial Magnetic Stimulation for People With Schizophrenia Treated With Clozapine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-01

Completion:

2026-01-12

Conditions

• Schizophrenia
• Schizoaffective Disorder

Interventions

• DEVICE

No Results Yet

NCT06000020 | COMPLETED

1435 participants

Leave or Laparoscopic Appendectomy With Normal Findings - a Regional Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2017-03-17

Completion:

2025-04-01

Conditions

• Appendicitis Acute

Interventions

• PROCEDURE

No Results Yet

NCT05987774 | RECRUITING | NA

540 participants

Improving Social Communication in Individuals With ASD Using AI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-10-15

Completion:

2027-06-30

Conditions

• Autism Spectrum Disorder

Interventions

• DEVICE

No Results Yet

NCT05976555 | RECRUITING | PHASE1

30 participants

Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-05-15

Completion:

2028-05-31

Conditions

• Multiple Myeloma

Interventions

• BIOLOGICAL

No Results Yet

NCT05960448 | ACTIVE_NOT_RECRUITING | NA

20 participants

Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-07-30

Completion:

2026-07-30

Conditions

• Orthostatic Hypotension

Interventions

• OTHER

No Results Yet

NCT05954832 | RECRUITING

250 participants

A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2023-07-13

Completion:

2027-07-31

Conditions

• Anesthesia

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05952557 | ACTIVE_NOT_RECRUITING | PHASE3

5511 participants

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-10-05

Completion:

2030-03-04

Conditions

• Breast Cancer, Early Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05936359 | ACTIVE_NOT_RECRUITING | PHASE1

160 participants

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-09-25

Completion:

2028-02-29

Conditions

• Myeloproliferative Neoplasms

Interventions

• DRUG

No Results Yet

NCT05930041 | ACTIVE_NOT_RECRUITING | NA

124 participants

Injured Submucosal Arteries After CSP for 10-19 mm Nonpedunculated Colorectal Polyps.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-01-01

Completion:

2024-12-31

Conditions

• Colonic Polyp

Interventions

• PROCEDURE

No Results Yet

NCT05926011 | RECRUITING | NA

108 participants

Efficacy of RGn600 in Patients With Mild-to-moderate Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-07-24

Completion:

2027-06-30

Conditions

• Alzheimer Disease

Interventions

• DEVICE

No Results Yet

NCT05901285 | RECRUITING | PHASE1

48 participants

Phase 1 Study of Intratumoral Administration of VAX014 With Expansion in Combination With a Checkpoint Inhibitor in Subjects With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-11-02

Completion:

2027-08-31

Conditions

• Advanced Solid Tumor
• Advanced Solid Tumors Appropriate for Treatment With Either Nivolumab or Pembrolizumab

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT05893966 | RECRUITING

400 participants

Prospective Cohort for Tumor Bed Boost Radiotherapy in HER2 Positive Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2022-11-29

Completion:

2030-11-29

Conditions

• Breast Cancer

Interventions

• RADIATION

No Results Yet