Clinical Trials

NCT05879146 | RECRUITING | PHASE2

40 participants

Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2024-11-26
Completion:: 2027-01-31

Conditions

Tumor

Interventions

DRUG

No Results Yet

NCT05878860 | RECRUITING | PHASE3

97 participants

ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-08-22
Completion:: 2028-04-30

Conditions

X-linked Retinoschisis

Interventions

BIOLOGICAL

No Results Yet

NCT05874011 | TERMINATED

26 participants

Prosody Assessment After Right Hemisphere Stroke

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2026-06-15
Completion:: 2026-06-15

Conditions

Right Hemisphere Stroke

Interventions

OTHER

No Results Yet

NCT05873569 | ACTIVE_NOT_RECRUITING | NA

300 participants

Preventing Postpartum Depression in Immigrant Latinas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-10-15
Completion:: 2027-01-31

Conditions

Postpartum Depression

Interventions

BEHAVIORAL

No Results Yet

NCT05862285 | RECRUITING | PHASE3

100 participants

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-06-01
Completion:: 2033-03-01

Conditions

Cancer

Interventions

DRUG

No Results Yet

NCT05856955 | NOT_YET_RECRUITING | NA

40 participants

Mobile Health Management of Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2027-09-30
Completion:: 2028-08-31

Conditions

Hypertension

Interventions

BEHAVIORAL

No Results Yet

NCT05855694 | NOT_YET_RECRUITING | NA

30 participants

Photobiomodulation for Cancer-Related Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2026-10-31
Completion:: 2028-10-31

Conditions

Cancer-related Cognitive Impairment

Interventions

DEVICE

No Results Yet

NCT05840484 | RECRUITING

100 participants

Comprehensive Monitoring of Men With Prostate Cancer Cared for by "Active Surveillance

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-03-29
Completion:: 2029-07-30

Conditions

Prostate Cancer

Interventions

OTHER

No Results Yet

NCT05839652 | RECRUITING | PHASE4

25 participants

Treatment of Orthostatic Hypotension in SCI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-07-01
Completion:: 2027-06-30

Conditions

Hypotension

Interventions

DRUG

No Results Yet

NCT05835999 | COMPLETED | PHASE2

106 participants

Everolimus Aging Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-03-24
Completion:: 2026-06-30

Conditions

Aging
Insulin Resistance

Interventions

DRUG

No Results Yet

NCT05832086 | RECRUITING | PHASE2

138 participants

Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-09-13
Completion:: 2028-09-30

Conditions

Prostate Adenocarcinoma

Interventions

BEHAVIORAL

No Results Yet

NCT05818098 | COMPLETED | NA

189 participants

Coronary Intravascular Lithotripsy System in Patients With Coronary Artery Calcification (VIGOUR)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-03-29
Completion:: 2023-09-15

Conditions

Coronary Artery Calcification

Interventions

DEVICE

No Results Yet

NCT05814510 | RECRUITING | NA

1000 participants

Implementation of Asthma Community Home and School Management Program (Asthma CHAMPS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-11-27
Completion:: 2027-06-30

Conditions

Asthma in Children

Interventions

BEHAVIORAL

No Results Yet

NCT05813704 | COMPLETED | NA

159 participants

Coronary Crossing System in Patients With Coronary Chronic Total Occlusions

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-11-07
Completion:: 2024-07-19

Conditions

Chronic Total Occlusion of Coronary Artery

Interventions

DEVICE

No Results Yet

NCT05810181 | RECRUITING

145 participants

Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-06-01
Completion:: 2027-12-31

Conditions

Sickle Cell Disease

Interventions

OTHER

No Results Yet

NCT05805501 | ACTIVE_NOT_RECRUITING | PHASE2

199 participants

A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-04-21
Completion:: 2026-10-08

Conditions

Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05800665 | RECRUITING | PHASE1

210 participants

A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-05-02
Completion:: 2027-06-30

Conditions

Advanced Prostate Cancer
Metastatic Prostate Cancer

Interventions

DRUG

No Results Yet

NCT05789082 | RECRUITING | PHASE1/PHASE2

320 participants

A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-06-20
Completion:: 2032-01-29

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05783635 | ACTIVE_NOT_RECRUITING | NA

440 participants

Alcohol Screening and Preoperative Intervention Research Study - 2

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-04-17
Completion:: 2027-02-28

Conditions

Alcohol Drinking

Interventions

BEHAVIORAL

No Results Yet

NCT05775757 | ACTIVE_NOT_RECRUITING

500 participants

SMC Radiation Oncology Breast Cancer Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-01-01
Completion:: 2030-12-31

Conditions

Radiotherapy Side Effect

Interventions

RADIATION

No Results Yet

NCT05774756 | ACTIVE_NOT_RECRUITING | PHASE3

143 participants

A Trial of Setmelanotide in Acquired Hypothalamic Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-04-26
Completion:: 2025-03-18

Conditions

Hypothalamic Obesity

Interventions

DRUG

Results Available

NCT05763771 | ACTIVE_NOT_RECRUITING | NA

56 participants

Smartphone-delivered Scheduled Smoking With Compliance Facilitation as an Adjunct Cessation Therapy: a Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2024-02-15
Completion:: 2027-12-01

Conditions

Smoking

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05743478 | ACTIVE_NOT_RECRUITING | NA

542 participants

Forging Hopeful Futures to Reduce Youth Violence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-07-10
Completion:: 2026-08-30

Conditions

Violence in Adolescence
Racism
Adolescent Behavior
Coping Skills
Communication, Social
Communication, Personal
Violence, Sexual
Violence, Non-accidental
Violence, Physical
Violence, Gender-Based

Interventions

BEHAVIORAL

No Results Yet

NCT05734196 | ACTIVE_NOT_RECRUITING | PHASE1

16 participants

The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-06-25
Completion:: 2026-10-14

Conditions

Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency
Autosomal Recessive Hypophosphatemic Rickets
Generalized Arterial Calcification of Infancy
ATP-Binding Cassette Subfamily C Member 6 Deficiency
Pseudoxanthoma Elasticum

Interventions

DRUG

No Results Yet

NCT05718817 | ENROLLING_BY_INVITATION | PHASE3

880 participants

An Open-label Study of XEN1101 in Epilepsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-04-25
Completion:: 2033-04-30

Conditions

Focal Epilepsy
Tonic-Clonic Seizures

Interventions

DRUG

No Results Yet

NCT05714085 | RECRUITING | PHASE2/PHASE3

342 participants

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-05-31
Completion:: 2032-04-15

Conditions

Heart Failure
Left Ventricular Systolic Dysfunction

Interventions

DRUG

No Results Yet

NCT05711940 | ACTIVE_NOT_RECRUITING | PHASE3

572 participants

Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-02-14
Completion:: 2025-11-13

Conditions

Treatment Resistant Depression

Interventions

DRUG

No Results Yet

NCT05709327 | ACTIVE_NOT_RECRUITING | NA

82 participants

Integrating Smart Ring Wearable Technology in Pregnancy Health Monitoring (I-SMART)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-09-03
Completion:: 2026-12-31

Conditions

Pregnancy

Interventions

OTHER

No Results Yet

NCT05704491 | RECRUITING

100 participants

AI Screening for Diabetic Retinopathy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-01-30
Completion:: 2027-12-31

Conditions

Diabetes Mellitus

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05694559 | RECRUITING | NA

1000 participants

Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-11-23
Completion:: 2027-02-02

Conditions

Breast Cancer
Colorectal Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05693896 | NOT_YET_RECRUITING | NA

60 participants

Treating Binge Eating and Obesity Digitally in Women

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2026-09-30
Completion:: 2027-09-30

Conditions

Binge Eating
Binge-Eating Disorder
Weight Gain Prevention
Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05686551 | ACTIVE_NOT_RECRUITING | PHASE2

301 participants

GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-02-03
Completion:: 2026-05-14

Conditions

Huntington Disease

Interventions

DRUG

No Results Yet

NCT05683457 | ACTIVE_NOT_RECRUITING | PHASE2

84 participants

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-04-05
Completion:: 2027-03-06

Conditions

Cytomegalovirus Infection

Interventions

BIOLOGICAL

No Results Yet

NCT05681624 | RECRUITING | NA

2252 participants

Maternal Oxygen Supplementation for Intrauterine Resuscitation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-05-22
Completion:: 2028-02-28

Conditions

Fetal Distress
Fetal Hypoxia
Labor and Delivery Complication

Interventions

OTHER

No Results Yet

NCT05674396 | RECRUITING | PHASE2

108 participants

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-06-30
Completion:: 2027-09-30

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

RADIATION

No Results Yet

NCT05667142 | RECRUITING | PHASE3

160 participants

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-02-14
Completion:: 2027-04-30

Conditions

Primary Generalized Tonic-Clonic Seizures

Interventions

DRUG

No Results Yet

NCT05664737 | RECRUITING | PHASE2

189 participants

A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-Thalassemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-12-09
Completion:: 2027-07-16

Conditions

Anemia

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05654103 | ACTIVE_NOT_RECRUITING | NA

90 participants

Comparing Surgical and Endovascular Arteriovenous Fistula Creation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2024-11-20
Completion:: 2026-10-31

Conditions

End Stage Renal Disease on Dialysis

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT05630781 | RECRUITING | NA

140 participants

Orexin s Role in the Neurobiology of Substance Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-02-15
Completion:: 2027-12-31

Conditions

Nicotine Dependence

Interventions

DRUG

No Results Yet

NCT05624268 | COMPLETED | PHASE3

258 participants

Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-01-24
Completion:: 2025-05-28

Conditions

Treatment Resistant Depression

Interventions

DRUG

No Results Yet