Clinical Trials

NCT05664737 | RECRUITING | PHASE2

189 participants

A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-Thalassemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-12-09

Completion:

2027-07-16

Conditions

• Anemia

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT05654103 | ACTIVE_NOT_RECRUITING | NA

90 participants

Comparing Surgical and Endovascular Arteriovenous Fistula Creation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-11-20

Completion:

2026-10-31

Conditions

• End Stage Renal Disease on Dialysis

Interventions

• DEVICE
• PROCEDURE

No Results Yet

NCT05630781 | RECRUITING | NA

140 participants

Orexin s Role in the Neurobiology of Substance Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-02-15

Completion:

2027-12-31

Conditions

• Nicotine Dependence

Interventions

• DRUG

No Results Yet

NCT05624268 | COMPLETED | PHASE3

258 participants

Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-01-24

Completion:

2025-05-28

Conditions

• Treatment Resistant Depression

Interventions

• DRUG

No Results Yet

NCT05611801 | RECRUITING | PHASE3

100 participants

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-12-09

Completion:

2028-09-10

Conditions

• Hemophilia A
• Hemophilia B

Interventions

• DRUG

No Results Yet

NCT05604222 | ACTIVE_NOT_RECRUITING | PHASE4

120 participants

Effect of Behavioral Sleep Intervention on Lower Urinary Tract Symptoms in Older Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-03-05

Completion:

2026-06-30

Conditions

• Urgency Urinary Incontinence
• Nocturia

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT05573841 | COMPLETED

161 participants

Transfusion for Major Haemorrhage in Trauma - Characteristics and Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2022-10-31

Completion:

2024-12-31

Conditions

• Trauma
• Hemorrhage
• Shock, Traumatic
• Acute Coagulopathy

No Results Yet

NCT05564377 | RECRUITING | PHASE2

2900 participants

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-04-07

Completion:

2030-07-01

Conditions

• Advanced Malignant Solid Neoplasm
• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Locally Advanced Malignant Solid Neoplasm
• Malignant Female Reproductive System Neoplasm
• Metastatic HER2-Negative Breast Carcinoma
• Metastatic Malignant Solid Neoplasm
• Recurrent Endometrial Carcinoma
• Recurrent Fallopian Tube Carcinoma
• Recurrent Malignant Female Reproductive System Neoplasm
• Recurrent Malignant Solid Neoplasm
• Recurrent Ovarian Carcinoma
• Recurrent Primary Peritoneal Carcinoma
• Unresectable HER2-Negative Breast Carcinoma
• Unresectable Malignant Solid Neoplasm

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT05561738 | TERMINATED | NA

19 participants

Nicotinamide Riboside in Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2024-02-28

Completion:

2026-06-30

Conditions

• Ulcerative Colitis

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT05560893 | COMPLETED | NA

84 participants

The Heart of the Community Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-11-02

Completion:

2024-09-30

Conditions

• Heart Rate Variability

Interventions

• BEHAVIORAL

Results Available

NCT05555485 | RECRUITING | NA

60 participants

Understanding the Effects of Transcutaneous Auricular Neurostimulation for Treatment of Chronic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-05-24

Completion:

2027-07-21

Conditions

• Opioid Withdrawal
• Analgesia

Interventions

• DEVICE

No Results Yet

NCT05554133 | RECRUITING | NA

90 participants

Precision Optical Guidance for Oral Biopsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-06-15

Completion:

2027-03-31

Conditions

• Oral Lesions

Interventions

• DEVICE
• DRUG

No Results Yet

NCT05541887 | SUSPENDED | NA

25 participants

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-08-30

Completion:

2028-12-31

Conditions

• Cognitive Performance
• Memory
• Mood
• Anxiety

Interventions

• OTHER

No Results Yet

NCT05541406 | ACTIVE_NOT_RECRUITING | NA

228 participants

Efficacy of a Multi-level School Intervention for LGBTQ Youth

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-09-14

Completion:

2025-07-01

Conditions

• Depression
• Anxiety
• Post Traumatic Stress Disorder
• Coping Behavior
• Sexual Minority Stress
• Suicidality
• Substance Use
• Bullying
• Harassment

Interventions

• BEHAVIORAL

No Results Yet

NCT05538910 | RECRUITING | NA

620 participants

Defining Neurobiological Links Between Substance Use and Mental Illness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-02-02

Completion:

2027-12-30

Conditions

• Major Depressive Disorder
• Substance Use Disorder
• Normal Physiology

Interventions

• OTHER
• DRUG

No Results Yet

NCT05534087 | RECRUITING | PHASE3

236 participants

Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer (KCSG CO22-12)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-12-15

Completion:

2028-09-30

Conditions

• Colon Cancer

Interventions

• DRUG

No Results Yet

NCT05531656 | ACTIVE_NOT_RECRUITING | PHASE2

540 participants

A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-06-28

Completion:

2027-05-31

Conditions

• Early Alzheimer's Disease

Interventions

• DRUG

No Results Yet

NCT05520346 | RECRUITING | NA

54 participants

Testing a Device for Automatically TRacking Urine and STool in an Inpatient HCT Setting (Project TRUST)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-09-13

Completion:

2028-08-31

Conditions

• Fluid Output

Interventions

• DEVICE

No Results Yet

NCT05518916 | COMPLETED | NA

48 participants

Effects of Yakson Method and Swaddling on Pain and Physiological Parameters

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-10-01

Completion:

2022-12-01

Conditions

• Pain During Heal Lancing

Interventions

• OTHER

No Results Yet

NCT05518903 | RECRUITING | PHASE2

130 participants

Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-11-15

Completion:

2027-06-30

Conditions

• Localized Pancreatic Adenocarcinoma
• Resectable Pancreatic Ductal Adenocarcinoma
• Stage 0 Pancreatic Cancer AJCC v8
• Stage I Pancreatic Cancer AJCC v8
• Stage IIA Pancreatic Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05512364 | RECRUITING | PHASE3

220 participants

Elacestrant for Treating ER+/HER2- Breast Cancer Patients With ctDNA Relapse (TREAT ctDNA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-15

Completion:

2032-11-01

Conditions

• ER-positive Breast Cancer
• HER2-negative Breast Cancer
• Stage IIB Breast Cancer
• Stage III Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05511285 | RECRUITING | NA

100 participants

Improving Sleep and Learning in Rehabilitation After Stroke, Part 2

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-09-13

Completion:

2027-06-30

Conditions

• Stroke

Interventions

• BEHAVIORAL

No Results Yet

NCT05504720 | COMPLETED | PHASE2

31 participants

Evaluating Pembrolizumab, Trastuzumab and FLOT as Perioperative Treatment of HER2-positive, Localized Esophagogastric Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-02-13

Completion:

2026-07-15

Conditions

• Esophagogastric Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT05502341 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

689 participants

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-08-16

Completion:

2025-09-29

Conditions

• HIV-1-infection

Interventions

• DRUG

No Results Yet

NCT05477862 | ENROLLING_BY_INVITATION | NA

30 participants

Neural Mechanisms of Clinically Designed Improvisatory Music for Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-09-01

Completion:

2026-12-15

Conditions

• Alzheimer Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT05447585 | COMPLETED | NA

239 participants

Coronary Atherectomy System in Patients With Coronary Calcification (CORECT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-07-01

Completion:

2023-08-10

Conditions

• Calcification of Coronary Artery

Interventions

• DEVICE

No Results Yet

NCT05428943 | COMPLETED | PHASE1

24 participants

OPT101 in Type 1 Diabetes Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-09-27

Completion:

2024-02-21

Conditions

• Diabetes Mellitus, Type 1

Interventions

• DRUG

Results Available

NCT05416125 | COMPLETED | EARLY_PHASE1

44 participants

Vyvanse in Children Aged 6 to 12 Years

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-12-20

Completion:

2026-06-23

Conditions

• Obesity, Childhood

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT05406284 | COMPLETED

43 participants

DK Nano-Culotte Stenting For Coronary Bifurcation Lesion

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2024-07-01

Completion:

2026-07-15

Conditions

• Coronary Artery Disease

Interventions

• PROCEDURE

No Results Yet

NCT05389293 | RECRUITING | PHASE2

152 participants

A Study of Mosunetuzumab Alone or With Zanubrutinib in People With Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-05-27

Completion:

2027-12-31

Conditions

• Follicular Lymphoma
• Lymphoma

Interventions

• DRUG

No Results Yet

NCT05382325 | ACTIVE_NOT_RECRUITING | PHASE1

70 participants

A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic Solid Tumors (MK-1484-001)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-06-16

Completion:

2026-09-30

Conditions

• Advanced or Metastatic Solid Tumors

Interventions

• BIOLOGICAL

No Results Yet

NCT05379868 | COMPLETED | NA

116 participants

Posterior Column Spinal Osteotomies in the Treatment of Adolescent Idiopathic Scoliosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-06-01

Completion:

2026-08-07

Conditions

• Adolescent Idiopathic Scoliosis

Interventions

• PROCEDURE

No Results Yet

NCT05377125 | RECRUITING | NA

118 participants

Neural Mechanisms of Response Inhibition Training for OCRD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-12-22

Completion:

2027-07-31

Conditions

• Obsessive-Compulsive Disorder
• Tricholemmoma
• Skin-Picking

Interventions

• BEHAVIORAL

No Results Yet

NCT05372484 | RECRUITING | NA

678 participants

Rice Technologies for Cervical Cancer Screening and Diagnosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-03-24

Completion:

2028-03-30

Conditions

• Cervical Cancer

Interventions

• DEVICE

No Results Yet

NCT05348863 | RECRUITING | NA

360 participants

SPARK- a Digital Platform to Improve Self-management of Gestational Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-10-28

Completion:

2026-12-31

Conditions

• Gestational Diabetes Mellitus

Interventions

• BEHAVIORAL

No Results Yet

NCT05337826 | ACTIVE_NOT_RECRUITING | NA

122 participants

The REST Study for CGM Use in Older Adults With Insulin-treated Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-04-20

Completion:

2025-11-11

Conditions

• Diabetes Mellitus

Interventions

• DEVICE

No Results Yet

NCT05308264 | RECRUITING | PHASE1/PHASE2

86 participants

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-09-12

Completion:

2026-08-31

Conditions

• Low Risk Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT05285891 | RECRUITING | PHASE4

123 participants

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-02-07

Completion:

2030-05-01

Conditions

• Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT05264974 | RECRUITING | PHASE1

18 participants

Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-03-17

Completion:

2026-12-31

Conditions

• Melanoma
• Soft Tissue Sarcoma

Interventions

• BIOLOGICAL

No Results Yet

NCT05262556 | COMPLETED | PHASE1

15 participants

NP-101 (TQ Formula) With Nivolumab and Ipilimumab in Advanced or Metastatic Extra-pulmonary Neuroendocrine Carcinomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-12-15

Completion:

2025-10-27

Conditions

• Gastroenteropancreatic Neuroendocrine Tumor
• Gastroenteropancreatic Neuroendocrine Neoplasm
• Neuroendocrine Carcinoma
• Mixed Neuroendocrine-Non Neuroendocrine Neoplasm

Interventions

• DRUG

No Results Yet