Clinical Trials

NCT06430801 | RECRUITING | PHASE3

1200 participants

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-05
Completion:: 2028-10-30

Conditions

Crohn's Disease

Interventions

OTHER
DRUG

No Results Yet

NCT06424509 | ACTIVE_NOT_RECRUITING

390 participants

Effects of Psychiatric Admissions on Self-harm and Suicide in People With Borderline Personality Disorder

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2010-01-01
Completion:: 2024-12-01

Conditions

Borderline Personality Disorder
Self-harm
Non-suicidal Self-injury
Suicide

Interventions

OTHER

No Results Yet

NCT06424327 | RECRUITING

600 participants

A Registry for People With Lung Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-05-15
Completion:: 2029-05-15

Conditions

Lung Cancer
Lung Cancer Stage I

Interventions

OTHER

No Results Yet

NCT06422143 | RECRUITING | PHASE3

851 participants

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-10
Completion:: 2029-01-12

Conditions

Non-small Cell Lung Cancer
NSCLC

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06402968 | RECRUITING

1018 participants

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-01
Completion:: 2028-01-30

Conditions

Intracerebral Hemorrhage
Stroke
Hypertension

Interventions

DRUG

No Results Yet

NCT06399302 | RECRUITING

2600 participants

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-09-03
Completion:: 2027-06-30

Conditions

Lung Transplant; Complications
Lung Transplant; Infection or Inflammation
Lung Transplant Rejection
Lung Transplant Failure

No Results Yet

NCT06393374 | RECRUITING | PHASE3

1530 participants

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-24
Completion:: 2030-12-16

Conditions

Triple-Negative Breast Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06391294 | ENROLLING_BY_INVITATION | NA

65 participants

Neuronal and Network Mechanisms of Electrocortical Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-05-17
Completion:: 2029-06-30

Conditions

Epilepsy
Brain Tumor Adult

Interventions

PROCEDURE

No Results Yet

NCT06381180 | RECRUITING | PHASE1/PHASE2

500 participants

Warrior CARE: Cannabis Behavioral Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-09-22
Completion:: 2030-12-31

Conditions

Post Traumatic Stress Disorder
Cannabis Use
Suicide
Veterans
Marijuana

Interventions

DRUG

No Results Yet

NCT06329921 | ENROLLING_BY_INVITATION | NA

700 participants

Inpatient Monitoring of Unfractionated Heparin

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-26
Completion:: 2026-09-30

Conditions

Blood Clot
Thrombosis

Interventions

OTHER

No Results Yet

NCT06328062 | RECRUITING | NA

80 participants

Comparing Efficiency of Mirogabalin and Pregabalin in Primary TKA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-04-01
Completion:: 2026-08-31

Conditions

Pain Postoperative
Osteoarthritis
Total Knee Arthroplasty

Interventions

DRUG

No Results Yet

NCT06319222 | COMPLETED | NA

145 participants

Implementation of a Digital Clinic for Alcohol-associated Liver Disease and Alcohol Use Disorder (DALC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-03-12
Completion:: 2026-07-31

Conditions

Alcohol Use Disorder
Liver Diseases

Interventions

OTHER

No Results Yet

NCT06317662 | RECRUITING | PHASE2

153 participants

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-06-05
Completion:: 2028-12-31

Conditions

Acute Leukemia of Ambiguous Lineage
B Acute Lymphoblastic Leukemia

Interventions

DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT06305598 | ACTIVE_NOT_RECRUITING | PHASE1

3 participants

Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-12-19
Completion:: 2026-03-09

Conditions

Castration-Resistant Prostate Carcinoma
Metastatic Prostate Carcinoma
Stage IVB Prostate Cancer AJCC v8

Interventions

PROCEDURE
DRUG
OTHER

No Results Yet

NCT06285825 | RECRUITING | PHASE2

32 participants

A Pilot Study of Emapalumab for the Treatment of CAR T-Cell Therapy-Associated Prolonged Cytopenia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-07-05
Completion:: 2028-08-22

Conditions

Cytopenia

Interventions

DRUG

No Results Yet

NCT06269757 | NOT_YET_RECRUITING | NA

100 participants

Exercise Program for ITB Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2027-03-01
Completion:: 2027-07-01

Conditions

Iliotibial Band Syndrome

Interventions

BEHAVIORAL

No Results Yet

NCT06266403 | RECRUITING | NA

300 participants

Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-11-05
Completion:: 2029-02-28

Conditions

Amyotrophic Lateral Sclerosis

Interventions

BEHAVIORAL

No Results Yet

NCT06265545 | RECRUITING | NA

458 participants

Multicenter, Platform-type Clinical Study of Refractory/Recurrent Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-02-22
Completion:: 2028-01-30

Conditions

AML
Refractory
Relapsed

Interventions

DRUG

No Results Yet

NCT06262178 | RECRUITING | NA

120 participants

Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-07-21
Completion:: 2027-05-31

Conditions

PTSD
Depression
Parent-Child Relations

Interventions

BEHAVIORAL

No Results Yet

NCT06251843 | COMPLETED

30 participants

Support Strategies for Parents During the First Year Following Their Child's Diagnosis of Sickle Cell Disorder

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-28
Completion:: 2025-03-31

Conditions

Sickle Cell Disease

No Results Yet

NCT06247085 | RECRUITING | PHASE3

70 participants

A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-12-28
Completion:: 2027-08-31

Conditions

Homocystinuria

Interventions

DRUG
OTHER

No Results Yet

NCT06237595 | COMPLETED | NA

87 participants

Vagus Nerve Stimulation in Fibromyalgia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-09-30
Completion:: 2025-02-15

Conditions

Fibromyalgia

Interventions

DEVICE
DRUG
COMBINATION_PRODUCT

No Results Yet

NCT06232512 | COMPLETED | NA

100 participants

Multimodal Haptic Feedback for Plantar Sensory Substitution

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-04-20
Completion:: 2026-06-23

Conditions

Hypoesthesia

Interventions

DEVICE

No Results Yet

NCT06224439 | COMPLETED | NA

115 participants

Comparison of Regional Anaesthesia Methods for Femoral Neck Fracture Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-01-25
Completion:: 2025-04-01

Conditions

Femoral Neck Fractures
Regional Anesthesia

Interventions

PROCEDURE

No Results Yet

NCT06223555 | RECRUITING | NA

79 participants

Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-08-23
Completion:: 2027-06-30

Conditions

Obesity
Healthy Volunteer

Interventions

OTHER

No Results Yet

NCT06217575 | ACTIVE_NOT_RECRUITING | NA

36 participants

Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-07-01
Completion:: 2028-01-30

Conditions

Traumatic Brain Injury
Mild Traumatic Brain Injury
Aging
Cognitive Decline

Interventions

BEHAVIORAL

No Results Yet

NCT06215716 | RECRUITING | PHASE3

1650 participants

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-12-01
Completion:: 2033-02-28

Conditions

NASH With Fibrosis
MASH With Fibrosis

Interventions

DRUG

No Results Yet

NCT06203626 | RECRUITING

200 participants

Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-03-26
Completion:: 2027-12-31

Conditions

Nervous System Diseases (C10 Unique ID D009422)

No Results Yet

NCT06190613 | RECRUITING | NA

110 participants

Combination Intervention to Enhance Treatment Engagement and Viral Suppression Among Sexual and Gender Minority Youth in Nigeria

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-11-28
Completion:: 2026-12-31

Conditions

HIV

Interventions

BEHAVIORAL

No Results Yet

NCT06180044 | COMPLETED

8 participants

Physiologic Burden to the Surgeon During Orthopaedic Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-11-28
Completion:: 2026-08-03

Conditions

Physiological Stress

No Results Yet

NCT06177483 | COMPLETED | NA

25 participants

Enhanced Absorption of curQ+ or Liposomal Curcumin Formulations Versus 95% Curcumin Powder in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-03-01
Completion:: 2024-04-05

Conditions

Bioavailability

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06137365 | RECRUITING | PHASE2

40 participants

Cannabis for Obesity Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2026-08-05
Completion:: 2028-03-31

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06136559 | RECRUITING | PHASE3

1200 participants

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-12-13
Completion:: 2032-09-07

Conditions

Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma

Interventions

DRUG

No Results Yet

NCT06124625 | COMPLETED | NA

90 participants

Effects of Rehabilitation Combined With a Maintenance Program Compared to Rehabilitation Alone in Post-COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-01-31
Completion:: 2025-09-08

Conditions

Post-COVID-19 Syndrome

Interventions

PROCEDURE

No Results Yet

NCT06118255 | ACTIVE_NOT_RECRUITING | PHASE3

25 participants

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-05-21
Completion:: 2026-09-01

Conditions

Dravet Syndrome

Interventions

DRUG

No Results Yet

NCT06090669 | RECRUITING | PHASE1

75 participants

Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-12-19
Completion:: 2026-10-30

Conditions

Inherited Bone Marrow Failure Syndrome
Familial Platelet Disorder With Predisposition to Myeloid Malignancies

Interventions

DRUG
DEVICE

No Results Yet

NCT06088914 | ACTIVE_NOT_RECRUITING | NA

32 participants

Behavioral and Neural Correlates of Post-Stroke Fatigue

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-12-15
Completion:: 2026-08-31

Conditions

Stroke
Fatigue

Interventions

DEVICE

No Results Yet

NCT06077695 | RECRUITING | NA

9 participants

Cognitive Remediation of Working Memory Post Head Trauma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-11-06
Completion:: 2027-07-06

Conditions

Head Trauma

Interventions

OTHER

No Results Yet

NCT06073821 | ACTIVE_NOT_RECRUITING | PHASE3

652 participants

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-11-11
Completion:: 2032-02-29

Conditions

CLL

Interventions

DRUG

No Results Yet

NCT06066359 | RECRUITING | PHASE1/PHASE2

44 participants

Ph I/II Trial of Cord Blood-derived NK Cells With NY-ESO-1 TCR/IL-15 for R/R Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-11-30
Completion:: 2028-08-31

Conditions

Relapsed/Refractory Myeloma

Interventions

DRUG

No Results Yet