Clinical Trials

NCT06626035 | RECRUITING | PHASE3

500 participants

Evaluation of Analgesia for Cardiac Elective Surgery in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-12-17
Completion:: 2029-01-31

Conditions

Pediatric Cardiac Surgery

Interventions

DRUG

No Results Yet

NCT06624085 | ACTIVE_NOT_RECRUITING | PHASE1

50 participants

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-04-28
Completion:: 2027-03-22

Conditions

Lymphoma

Interventions

DRUG

No Results Yet

NCT06620692 | NOT_YET_RECRUITING | PHASE2

65 participants

A Study to Investigate the Efficacy and Safety Profile of GM-XANTHO [GM-XAN003] in Patients With Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2026-10-01
Completion:: 2027-12-31

Conditions

Psoriasis

Interventions

DRUG

No Results Yet

NCT06617325 | RECRUITING | PHASE3

450 participants

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-11-21
Completion:: 2028-05-31

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG
OTHER

No Results Yet

NCT06609915 | NOT_YET_RECRUITING | NA

40 participants

SuprAglottic Jet Ventilation vs High-flow Nasal Oxygen in Tubeless Laryngotracheal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2026-10-01
Completion:: 2028-12-31

Conditions

Airway Managment
Laryngotracheal Surgery

Interventions

DEVICE

No Results Yet

NCT06606327 | TERMINATED | PHASE1

1 participants

Diazoxide Suppression Test P&F Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-10-23
Completion:: 2026-06-10

Conditions

Insulin Resistance
Hyperinsulinemia
Obesity

Interventions

DRUG

No Results Yet

NCT06599515 | COMPLETED

50 participants

SetUp Study for HugoTM RAS Inguinal Hernia Repair

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2023-09-15
Completion:: 2025-02-07

Conditions

Inguinal Hernia

Interventions

PROCEDURE

No Results Yet

NCT06598800 | RECRUITING | PHASE1

153 participants

Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-10-18
Completion:: 2028-09-30

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06596694 | RECRUITING | PHASE1/PHASE2

180 participants

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-11-03
Completion:: 2028-12-07

Conditions

Gastrointestinal Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06580314 | RECRUITING | PHASE3

880 participants

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-03-12
Completion:: 2034-12-31

Conditions

Fallopian Tube Endometrioid Adenocarcinoma
Fallopian Tube High Grade Serous Adenocarcinoma
Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor
FIGO Stage III Ovarian Cancer 2014
FIGO Stage IV Ovarian Cancer 2014
Ovarian Carcinoma
Ovarian Carcinosarcoma
Ovarian High Grade Endometrioid Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Primary Peritoneal Carcinosarcoma
Primary Peritoneal Endometrioid Adenocarcinoma
Primary Peritoneal High Grade Serous Adenocarcinoma

Interventions

BIOLOGICAL
PROCEDURE
DRUG

No Results Yet

NCT06577363 | RECRUITING

250 participants

A Survey of Maribavir Tablets in Participants With Cytomegalovirus Infection

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-08-28
Completion:: 2028-06-30

Conditions

Cytomegalovirus (CMV)

Interventions

DRUG

No Results Yet

NCT06575374 | RECRUITING | PHASE2

36 participants

Single Arm Pilot Trial of Letermovir for CMV Prophy in CAR T Cell

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-12-12
Completion:: 2028-08-01

Conditions

Cell Therapy

Interventions

DRUG

No Results Yet

NCT06570798 | RECRUITING | PHASE2

220 participants

A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-07-16
Completion:: 2028-08-06

Conditions

Systemic Lupus Erythematosus
Active Refractory Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT06565078 | RECRUITING

100 participants

A Database Survey to Evaluate the Safety of Immune Globulin Subcutaneous (Human), 20% Solution in Participants With Primary Immunodeficiency

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-02-17
Completion:: 2030-03-31

Conditions

Primary Immunodeficiency Diseases (PID)

Interventions

DRUG

No Results Yet

NCT06561685 | RECRUITING | PHASE1

340 participants

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-09-19
Completion:: 2027-10-31

Conditions

Metastatic Solid Tumor
Advanced Solid Tumor
Non-small Cell Lung Cancer
SMARCA4-Deficient Tumor

Interventions

DRUG

No Results Yet

NCT06544278 | COMPLETED | NA

40 participants

The Impact of Probiotics on Sperm Quality in Middle-aged Men

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-08-30
Completion:: 2025-05-01

Conditions

Semen Quality

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06542250 | RECRUITING | PHASE1/PHASE2

174 participants

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-09-18
Completion:: 2029-12-18

Conditions

B-cell Malignancies

Interventions

DRUG

No Results Yet

NCT06523231 | COMPLETED | PHASE2

110 participants

Study to Expand Safety and Immunogenicity Data With Shigella Bioconjugate Vaccine (Shigella4V2) in 9-month-old Infants.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-04-07
Completion:: 2025-08-27

Conditions

Shigellosis

Interventions

BIOLOGICAL

No Results Yet

NCT06515990 | RECRUITING | PHASE1/PHASE2

208 participants

A Study of DM005 in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-10-31
Completion:: 2027-03-31

Conditions

Carcinoma, Non-Small-Cell Lung
Squamous Cell Carcinoma of Head and Neck
Solid Carcinoma

Interventions

DRUG

No Results Yet

NCT06514898 | RECRUITING | PHASE1

12 participants

Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-05-05
Completion:: 2027-09-01

Conditions

Recurrent Group 3 Medulloblastoma
Recurrent Group 4 (Non-SHH/Non-WNT) Medulloblastoma

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06510231 | RECRUITING | NA

68 participants

Inspiratory Muscle Training in HFpEF

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-10-09
Completion:: 2028-04-30

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT06498674 | COMPLETED | NA

515 participants

AI-Assisted Ultrasound Review Before Thyroid Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-09-01
Completion:: 2025-09-28

Conditions

Thyroid Cancer
Thyroid Nodule

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06493955 | NOT_YET_RECRUITING | NA

308 participants

Evaluation of the Effectiveness of Extending the "Passerelle" System for Prescribing Adapted Physical Activity to Patients With Type 2 Diabetes in Nouvelle-AQUItaine (France)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2026-09-30
Completion:: 2029-09-30

Conditions

Diabetes Mellitus, Type 2

Interventions

OTHER

No Results Yet

NCT06486051 | RECRUITING | PHASE2

60 participants

A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-07-12
Completion:: 2027-06-30

Conditions

Large B-cell Lymphoma
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Transformed Non-Hodgkin Lymphoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06476795 | RECRUITING | NA

5 participants

The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-01
Completion:: 2027-06-30

Conditions

Cardiovascular Diseases
Adiposity
Cardiometabolic Syndrome

Interventions

OTHER

No Results Yet

NCT06471257 | RECRUITING | PHASE3

1000 participants

A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-17
Completion:: 2027-10-04

Conditions

Asthma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06469944 | RECRUITING | PHASE1/PHASE2

160 participants

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-09-20
Completion:: 2029-09-12

Conditions

Gastroesophageal Junction
Gastroesophageal Adenocarcinoma
Esophageal Neoplasms
Esophageal Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06461533 | RECRUITING

25 participants

A Survey of Susoctocog Alfa (Genetical Recombination) in Participants With Acquired Haemophilia A

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-10
Completion:: 2028-05-31

Conditions

Acquired Hemophilia A

Interventions

DRUG

No Results Yet

NCT06459180 | ACTIVE_NOT_RECRUITING | PHASE3

686 participants

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-07-24
Completion:: 2028-06-15

Conditions

Cervical Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06455293 | RECRUITING | PHASE2

60 participants

Psilocybin Therapy for Depression in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-08-19
Completion:: 2027-06-30

Conditions

Parkinson Disease
Depression

Interventions

DRUG

No Results Yet

NCT06439277 | RECRUITING | PHASE3

300 participants

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-03
Completion:: 2027-10-31

Conditions

Obesity
Weight Gain

Interventions

DRUG

No Results Yet

NCT06431750 | WITHDRAWN

0 participants

Prospective Observational Study to Evaluate Secukinumab Treatment Effectiveness in Pediatric Patients With Active Juvenile Enthesitis-related or Psoriatic Arthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2025-04-30
Completion:: 2028-08-30

Conditions

Juvenile Idiopathic Arthritis

Interventions

OTHER

No Results Yet

NCT06430801 | RECRUITING | PHASE3

1200 participants

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-05
Completion:: 2028-10-30

Conditions

Crohn's Disease

Interventions

OTHER
DRUG

No Results Yet

NCT06424509 | ACTIVE_NOT_RECRUITING

390 participants

Effects of Psychiatric Admissions on Self-harm and Suicide in People With Borderline Personality Disorder

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2010-01-01
Completion:: 2024-12-01

Conditions

Borderline Personality Disorder
Self-harm
Non-suicidal Self-injury
Suicide

Interventions

OTHER

No Results Yet

NCT06424327 | RECRUITING

600 participants

A Registry for People With Lung Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-05-15
Completion:: 2029-05-15

Conditions

Lung Cancer
Lung Cancer Stage I

Interventions

OTHER

No Results Yet

NCT06422143 | RECRUITING | PHASE3

851 participants

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-10
Completion:: 2029-01-12

Conditions

Non-small Cell Lung Cancer
NSCLC

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06402968 | RECRUITING

1018 participants

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-01
Completion:: 2028-01-30

Conditions

Intracerebral Hemorrhage
Stroke
Hypertension

Interventions

DRUG

No Results Yet

NCT06399302 | RECRUITING

2600 participants

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-09-03
Completion:: 2027-06-30

Conditions

Lung Transplant; Complications
Lung Transplant; Infection or Inflammation
Lung Transplant Rejection
Lung Transplant Failure

No Results Yet

NCT06393374 | RECRUITING | PHASE3

1530 participants

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-06-24
Completion:: 2030-12-16

Conditions

Triple-Negative Breast Cancer

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT06391294 | ENROLLING_BY_INVITATION | NA

65 participants

Neuronal and Network Mechanisms of Electrocortical Stimulation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-07
Start Date:: 2024-05-17
Completion:: 2029-06-30

Conditions

Epilepsy
Brain Tumor Adult

Interventions

PROCEDURE

No Results Yet