Clinical Trials Updated in 2026

NCT05864053 | RECRUITING | PHASE1/PHASE2

25 participants

(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-09-19
Completion:: 2027-04-30

Conditions

Pain, Neuropathic

Interventions

DRUG

No Results Yet

NCT05852262 | COMPLETED | PHASE4

454 participants

High-dose Cephalexin for Cellulitis (HI-DOCC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-08-30
Completion:: 2026-04-05

Conditions

Cellulitis

Interventions

DRUG

No Results Yet

NCT05846841 | RECRUITING | NA

850 participants

Personalized Tobacco Treatment in Primary Care (MOTIVATE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-09-29
Completion:: 2028-03-31

Conditions

Physician's Role
Smoking Cessation
Smoking

Interventions

BEHAVIORAL

No Results Yet

NCT05844969 | COMPLETED

140 participants

Circle Method Observational Project - Non-interventional, Retrospective, Multicenter Data Collection

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2025-06-06
Completion:: 2026-06-01

Conditions

Aortic Stenosis With Bicuspid Valve

No Results Yet

NCT05842902 | RECRUITING | NA

80 participants

Resilience Mobile App for Teens and Young Adults With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-09-12
Completion:: 2027-08-01

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05842863 | ACTIVE_NOT_RECRUITING | NA

44 participants

Combined Dialectical Behavior Therapy and Digital Cognitive Behavioral Therapy for Insomnia for Adolescents at High Risk for Suicide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-08-14
Completion:: 2027-01-30

Conditions

Suicide and Self-harm

Interventions

BEHAVIORAL

No Results Yet

NCT05839730 | ACTIVE_NOT_RECRUITING | NA

105 participants

Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-09-11
Completion:: 2027-10-31

Conditions

Heart Failure With Preserved Ejection Fraction
Concentric Hypertrophy

Interventions

DEVICE

No Results Yet

NCT05833633 | COMPLETED

17 participants

Study of Genotype and Phenotype Characterization in Duchenne Muscular Dystrophy With Small Mutations

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-03-18
Completion:: 2025-04-30

Conditions

Muscular Dystrophy, Duchenne

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05820204 | ACTIVE_NOT_RECRUITING | NA

150 participants

Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-04-12
Completion:: 2025-08-25

Conditions

Pain, Chronic
Back Pain

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05807139 | RECRUITING | PHASE1

20 participants

Spironolactone in Alcohol Use Disorder (SAUD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-07-13
Completion:: 2026-12-31

Conditions

Alcohol Use Disorder

Interventions

OTHER
DRUG

No Results Yet

NCT05806138 | ACTIVE_NOT_RECRUITING | PHASE2

21 participants

A Study of Vericiguat in People With Breast Cancer and Cancer Therapy-Related Cardiac Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-07-17
Completion:: 2028-07-17

Conditions

Breast Cancer
Cardiac Dysfunction

Interventions

DRUG
OTHER

No Results Yet

NCT05798923 | RECRUITING | PHASE2

85 participants

LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-08-30
Completion:: 2027-07-16

Conditions

Pulmonary Hypertension Due to Lung Diseases and Hypoxia

Interventions

DRUG

No Results Yet

NCT05754710 | RECRUITING

10 participants

Korea Xeljanz Post-marketing Surveillance for Juvenile Idiopathic Arthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-04-12
Completion:: 2026-09-30

Conditions

Psoriatic Arthritis, Juvenile
Polyarticular Juvenile Idiopathic Arthritis

Interventions

DRUG

No Results Yet

NCT05753774 | TERMINATED | PHASE3

47 participants

Effect of Fecal Microbiota Transplantation (FMT) in Pediatric Functional Gastrointestinal Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-04-03
Completion:: 2026-01-05

Conditions

Functional Gastrointestinal Disorders

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05752799 | ACTIVE_NOT_RECRUITING | NA

70 participants

Evaluation of the Stress Response in Bariatric Surgery With and Without the Use of Opioids

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-01-01
Completion:: 2026-07-01

Conditions

Opioid Use, Unspecified
Bariatric Surgery Candidate

Interventions

DRUG

No Results Yet

NCT05737784 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

60 participants

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-04-13
Completion:: 2026-04-01

Conditions

SCN2A-DEE
Epilepsy

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05732727 | RECRUITING | PHASE3

720 participants

Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-03-28
Completion:: 2029-03-31

Conditions

Chronic Kidney Disease(CKD)
Uncontrolled Hypertension

Interventions

DRUG

No Results Yet

NCT05707806 | RECRUITING

550 participants

Development and Validation of Learning and Decision-Making Tasks

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-03-29
Completion:: 2032-12-31

Conditions

Normal Physiology

Interventions

DEVICE

No Results Yet

NCT05697861 | ENROLLING_BY_INVITATION

72 participants

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-07-10
Completion:: 2038-03-31

Conditions

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy
Wild-Type Transthyretin Cardiac Amyloidosis

No Results Yet

NCT05687110 | RECRUITING | PHASE1

43 participants

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-07-06
Completion:: 2028-07-01

Conditions

Metastatic Malignant Solid Neoplasm
Unresectable Malignant Solid Neoplasm

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT05677763 | ACTIVE_NOT_RECRUITING | PHASE4

525 participants

OM-85 in Paediatric Recurrent Respiratory Tract Infections With Wheezing Lower Respiratory Illness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-12-12
Completion:: 2026-03-10

Conditions

Respiratory Tract Infections
Wheezing Lower Respiratory Illness

Interventions

DRUG

No Results Yet

NCT05606406 | WITHDRAWN | NA

0 participants

Hypoxia and Heart Rate Variability

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2026-05-30
Completion:: 2026-07-29

Conditions

Pulmonary Disease, Chronic Obstructive
Hypoxia

Interventions

OTHER

No Results Yet

NCT05603910 | RECRUITING | PHASE1

18 participants

Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-04-15
Completion:: 2029-04-15

Conditions

Recurrent Endometrial Carcinoma
Unresectable Endometrial Carcinoma

Interventions

RADIATION
DRUG

No Results Yet

NCT05574465 | WITHDRAWN | NA

0 participants

Esophageal Manometry During Recovery From Endotracheal Intubation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2025-07-01
Completion:: 2027-06-30

Conditions

Motility Function

Interventions

DEVICE

No Results Yet

NCT05574361 | ACTIVE_NOT_RECRUITING | NA

385 participants

Continued Access Study to Evaluate Performance of the Organ Recovery Systems _LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant (PILOT™_CA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-09-19
Completion:: 2025-09-23

Conditions

Liver Transplantation

Interventions

DEVICE

No Results Yet

NCT05548647 | COMPLETED | PHASE4

120 participants

Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-07-26
Completion:: 2025-05-12

Conditions

Obesity

Interventions

BEHAVIORAL
DRUG

Results Available

NCT05526755 | ACTIVE_NOT_RECRUITING | PHASE2

188 participants

A Study of 5 Years of Adjuvant Osimertinib in Completely Resected Epidermal Growth Factor Receptor Mutation (EGFRm) Non-small Cell Lung Carcinoma (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-03-06
Completion:: 2029-11-22

Conditions

Stage II-IIIB Non-small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT05518500 | ACTIVE_NOT_RECRUITING | PHASE4

75 participants

A Deep Longitudinal Analysis of Next Generation Influenza Vaccines in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-08-31
Completion:: 2026-12-31

Conditions

Aging
Influenza Vaccine
Dendritic Cell
Vaccine Response

Interventions

BIOLOGICAL

No Results Yet

NCT05507008 | COMPLETED | NA

38 participants

Ketone Supplementation in Eating Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-10-13
Completion:: 2026-07-06

Conditions

Anorexia Nervosa
Bulimia Nervosa
Atypical Anorexia Nervosa
Atypical Bulimia Nervosa

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05462821 | COMPLETED | PHASE3

73 participants

Full-Time Occlusion Therapy for Intermittent Exotropia in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-11-01
Completion:: 2025-05-01

Conditions

Intermittent Exotropia

Interventions

DEVICE

Results Available

NCT05455359 | RECRUITING | PHASE4

120 participants

Gastrointestinal Dysmotility on Aspiration Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2025-02-13
Completion:: 2027-05-31

Conditions

Esophageal Motility Disorders
Gastric Motor Dysfunction
Aspiration Pneumonia
Gastro Esophageal Reflux

Interventions

DRUG

No Results Yet

NCT05443087 | RECRUITING | NA

330 participants

TARGETed Therapy Drug MONITOring in DIGestive Oncology

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-08-29
Completion:: 2026-08-31

Conditions

Digestive Cancer
Metastatic Colorectal Cancer
Hepatocellular Carcinoma
GIST
Neuroendocrine Tumors

Interventions

OTHER

No Results Yet

NCT05439733 | COMPLETED

16764 participants

Planned Mode of Delivery After Caesarean: a Comparative Prospective National Population-based Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-06-22
Completion:: 2026-01-13

Conditions

Scarred Uterus

Interventions

OTHER

No Results Yet

NCT05438537 | RECRUITING

300 participants

A Comprehensive Prospective Assessment of the Physical and Biological Effects of Upper Tract Urothelial Cancer (UTUC)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-11-01
Completion:: 2030-12-30

Conditions

Upper Tract Urothelial Cancer

No Results Yet

NCT05433142 | RECRUITING | PHASE1

307 participants

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-06-13
Completion:: 2027-02-28

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

BIOLOGICAL

No Results Yet

NCT05432791 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

74 participants

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-03-30
Completion:: 2024-08-13

Conditions

Locally Advanced Uterine Corpus Leiomyosarcoma
Metastatic Uterine Corpus Leiomyosarcoma
Stage III Uterine Corpus Leiomyosarcoma AJCC v8
Stage IV Uterine Corpus Leiomyosarcoma AJCC v8
Unresectable Uterine Corpus Leiomyosarcoma

Interventions

PROCEDURE
DRUG

Results Available

NCT05407636 | ACTIVE_NOT_RECRUITING | PHASE3

735 participants

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-01-13
Completion:: 2026-10-31

Conditions

AMD
nAMD
Wet Age-related Macular Degeneration
wAMD
WetAMD
CNV

Interventions

GENETIC
BIOLOGICAL

No Results Yet

NCT05390411 | ENROLLING_BY_INVITATION | NA

1463 participants

Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-03-06
Completion:: 2027-09-30

Conditions

Implementation Science
Heart Transplant
Decision Making

Interventions

BEHAVIORAL

No Results Yet

NCT05386628 | COMPLETED | NA

36 participants

The Effect of Myofascial Chain Release Techniques on Shoulder Joint Range of Motion in Breast Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-08-15
Completion:: 2025-01-15

Conditions

Breast Cancer Survivors

Interventions

OTHER

No Results Yet

NCT05370222 | COMPLETED | NA

64 participants

Adaptations of Exercise Energy Metabolism in Response to Weight Loss in Healthy Normal Weight People

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-05-26
Completion:: 2024-08-31

Conditions

Healthy
Weight Loss
Body Weight
Diet Habit
Healthy Nutrition

Interventions

BEHAVIORAL

No Results Yet