Clinical Trials

NCT07142239 | RECRUITING

150 participants

Hematological Markers MPV, PLR, and NLR in Primary Versus Secondary Antiphospholipid Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-11-27
Completion:: 2026-12-30

Conditions

Antiphospholipid Syndrome

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07141004 | RECRUITING | PHASE4

100 participants

A Study of Guselkumab Administered Subcutaneously in Treatment of Indian Participants With Psoriatic Arthritis (PsA)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-08-12
Completion:: 2027-06-05

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT07137429 | RECRUITING

400 participants

Platelet Volunteers, Longitudinal and Multi-omic Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-26
Completion:: 2041-09-15

Conditions

Thrombosis

No Results Yet

NCT07135882 | NOT_YET_RECRUITING | PHASE3

420 participants

Primary Radiotherapy In MEtastatic Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-08-25
Completion:: 2030-12-31

Conditions

Carcinoma, Non-Small-Cell Lung (NSCLC)

Interventions

COMBINATION_PRODUCT
DRUG

No Results Yet

NCT07135050 | RECRUITING | PHASE1/PHASE2

12 participants

Phase 1/2 Study of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-12-19
Completion:: 2029-03-31

Conditions

Pitt Hopkins Syndrome

Interventions

GENETIC

No Results Yet

NCT07132645 | RECRUITING | EARLY_PHASE1

30 participants

An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-09-16
Completion:: 2027-09-01

Conditions

Neuroendocrine Tumor

Interventions

PROCEDURE
DRUG

No Results Yet

NCT07129252 | RECRUITING | PHASE1/PHASE2

150 participants

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-11-26
Completion:: 2027-08-31

Conditions

SST2-positive Neuroendocrine Neoplasms
Neuroendocrine Tumors
Neuroendocrine Neoplasm

Interventions

DRUG

No Results Yet

NCT07125378 | RECRUITING | PHASE1/PHASE2

15 participants

Living Independence Through Functional Training

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-01-06
Completion:: 2026-11-30

Conditions

Mobility Limitation
Cognitive Impairment

Interventions

BEHAVIORAL

No Results Yet

NCT07124780 | RECRUITING | NA

40 participants

Helping Adults With Obsessive-Compulsive Disorder Succeed at Work

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-05-12
Completion:: 2027-08-31

Conditions

Obsessive-Compulsive Disorder (OCD)

Interventions

BEHAVIORAL

No Results Yet

NCT07121595 | RECRUITING | PHASE2

50 participants

Personalized Neck Radiation Therapy Directed by Sentinel Lymph Node Biopsy for the Treatment of Oral Cavity Squamous Cell Carcinoma, PRECEDENT Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-07-17
Completion:: 2030-07-01

Conditions

Oral Cavity Squamous Cell Carcinoma
Stage I Lip and Oral Cavity Cancer AJCC v8
Stage II Lip and Oral Cavity Cancer AJCC v8
Stage III Lip and Oral Cavity Cancer AJCC v8
Stage IVA Lip and Oral Cavity Cancer AJCC v8

Interventions

PROCEDURE
DRUG
OTHER
RADIATION

No Results Yet

NCT07117136 | RECRUITING

200 participants

Blinatumomab Consolidation in Real World

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-08-28
Completion:: 2029-05-14

Conditions

B-Cell Acute Lymphoblastic Leukaemia

No Results Yet

NCT07117058 | RECRUITING

545 participants

Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-03-18
Completion:: 2027-09-30

Conditions

Generalized Anxiety
Introspective & Anxiety-Prone Patient
Depression, Anxiety
Survivors of Childhood Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07115680 | COMPLETED

503 participants

Where Did the Authors Work When They Conducted Their Clinical Pharmacology Studies?

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-09-15
Completion:: 2025-11-04

Conditions

Scientific Collaboration in Clinical Pharmacology

Interventions

OTHER

No Results Yet

NCT07106632 | RECRUITING | PHASE3

3380 participants

Optimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent Breast Cancer Using Genomic Tests

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-06-26
Completion:: 2031-08-15

Conditions

Early Breast Cancer
Premenopausal Breast Cancer
HR+/HER2- Breast Cancer

Interventions

DRUG

No Results Yet

NCT07095504 | COMPLETED | NA

8 participants

A Study of Cardiac Rehabilitation Intervention to Improve Cardiovascular Health and Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-12-08
Completion:: 2026-06-01

Conditions

Cardiovascular Health

Interventions

BEHAVIORAL

No Results Yet

NCT07085104 | RECRUITING | PHASE1

66 participants

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-11-13
Completion:: 2028-02-29

Conditions

Systemic Lupus Erythematosus (With and Without Nephritis)
Idiopathic Inflammatory Myopathy
Systemic Sclerosis

Interventions

GENETIC
DRUG

No Results Yet

NCT07081711 | RECRUITING

1000 participants

Longitudinal Validation of CIRC Technologies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-05-06
Completion:: 2035-08-31

Conditions

Cardiovascular Diseases
Heart Failure
Ischemic Heart Disease
Non-ischemic Cardiomyopathy
Valvular Heart Disease
Metabolic Cardiomyopathy
Congenital Heart Disease
Aortic Diseases
Atrial Fibrillation
Ventricular Fibrillation

No Results Yet

NCT07081503 | RECRUITING | PHASE1

44 participants

Phase 1 Study of ADX-626 in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-08-12
Completion:: 2027-01-22

Conditions

Healthy Adult Participants

Interventions

DRUG

No Results Yet

NCT07069699 | RECRUITING | PHASE1/PHASE2

50 participants

Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-10-13
Completion:: 2030-01-31

Conditions

Burkitt Lymphoma
Double-Expressor Lymphoma
High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements

Interventions

PROCEDURE
DRUG

No Results Yet

NCT07067632 | ACTIVE_NOT_RECRUITING

100 participants

Mortality Outcome of Controlled Blood Pressure Participants

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-07-01
Completion:: 2026-12-31

Conditions

Valid MeSH Conditions
Hypertension (HTN)

Interventions

DRUG

No Results Yet

NCT07062471 | RECRUITING | NA

185 participants

Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-06-22
Completion:: 2027-10-31

Conditions

Carotid Artery Calcification
Carotid Artery Diseases

Interventions

DEVICE

No Results Yet

NCT07061951 | RECRUITING | PHASE2

20 participants

Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-05-27
Completion:: 2030-02-01

Conditions

Recurrent Chronic Lymphocytic Leukemia
Recurrent Small Lymphocytic Lymphoma
Refractory Chronic Lymphocytic Leukemia
Refractory Small Lymphocytic Lymphoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT07057089 | SUSPENDED | PHASE2

90 participants

Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-07-01
Completion:: 2028-03-01

Conditions

Locally Advanced Rectal Cancer

Interventions

DRUG
RADIATION
PROCEDURE

No Results Yet

NCT07053800 | RECRUITING | PHASE2

35 participants

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-01-16
Completion:: 2028-08-31

Conditions

Lupus Nephritis

Interventions

BIOLOGICAL

No Results Yet

NCT07037550 | ACTIVE_NOT_RECRUITING | NA

272 participants

Effectiveness of Strength-based Intervention for Elderly With Dementia Living in the Community

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-07-01
Completion:: 2026-02-28

Conditions

Dementia
Mild Cognitive Impairment
Caregiver
Dementia Alzheimer Type

Interventions

BEHAVIORAL

No Results Yet

NCT07037446 | ENROLLING_BY_INVITATION

200 participants

A Multicenter, International, Prospective and Retrospective, Follow-up Registry to Monitor the Efficacy and Safety of the Occlutech Paravalvular Leak Device (PLD) in Patients With Mitral or Aortic Paravalvular Leaks

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-02-05
Completion:: 2030-12-31

Conditions

Paravalvular Leak

Interventions

DEVICE

No Results Yet

NCT07036003 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

34 participants

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-10-31
Completion:: 2028-07-31

Conditions

Knee Osteoarthritis (Knee OA)
Knee Osteoarthritis (OA)

Interventions

DRUG

No Results Yet

NCT07033052 | RECRUITING | NA

110 participants

Developing Resilience and Anxiety Management Through the Arts

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-04-15
Completion:: 2027-07-01

Conditions

Anxiety
Depression
Mood

Interventions

BEHAVIORAL

No Results Yet

NCT07030517 | ACTIVE_NOT_RECRUITING | PHASE4

75 participants

A Study to Assess Safety of Teclistamab in Indian Participants With Relapsed and Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-05-22
Completion:: 2026-11-03

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT07015567 | RECRUITING | NA

288 participants

Treatment of Complex Post-traumatic Stress Disorder Among Displaced People in Switzerland and Germany

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-01-21
Completion:: 2030-12-31

Conditions

Complex Post-Traumatic Stress Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07013916 | RECRUITING | NA

72 participants

Fructose is a Metabolic and Inflammatory Pathogenic Factor in Metabolic Dysfunction-associated Steatohepatitis (MASH)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-06-30
Completion:: 2027-04-01

Conditions

MASH - Metabolic Dysfunction-Associated Steatohepatitis
MASH With Fibrosis
Steatosis of Liver

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07012031 | RECRUITING | PHASE1/PHASE2

37 participants

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-06-17
Completion:: 2027-06-14

Conditions

Locally Advanced Lung Non-Small Cell Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT07011719 | RECRUITING | PHASE3

720 participants

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-09-08
Completion:: 2028-04-30

Conditions

Metastatic Clear Cell Renal Cell Carcinoma
Advanced Clear Cell Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07010770 | RECRUITING | NA

240 participants

SMART Therapist Training: A Hybrid Factorial-SMART Design

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-08-15
Completion:: 2030-05-31

Conditions

Stress Disorders, Post-Traumatic
Psychotherapy

Interventions

OTHER

No Results Yet

NCT07006636 | RECRUITING | NA

22 participants

Effect of Watermelon on Cardiometabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-04-01
Completion:: 2027-09-01

Conditions

Cardiometabolic Health Indicators
Whole-body Antioxidant Capacity

Interventions

OTHER

No Results Yet

NCT07005154 | RECRUITING | PHASE2

218 participants

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-06-19
Completion:: 2032-05-31

Conditions

Prostate Cancer
Metastatic Castration-Resistant Prostate Cancer
Metastatic Hormone Sensitive Prostate Cancer

Interventions

DRUG

No Results Yet

NCT07003295 | RECRUITING | PHASE2

20 participants

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-07-08
Completion:: 2027-08-31

Conditions

Recurrent Mantle Cell Lymphoma
Refractory Mantle Cell Lymphoma

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet

NCT06993792 | ACTIVE_NOT_RECRUITING | PHASE3

1400 participants

A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-05-15
Completion:: 2027-08-31

Conditions

Obesity
Overweight
Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT06993740 | COMPLETED | NA

60 participants

Effect of Dexmedetomidine on Microsurgery Reconstruction in Cancer Patient

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-06-10
Completion:: 2026-03-06

Conditions

Flap Monitoring
Inflammation
Thrombosis
Oxidative Stress
Glycocalyx
Anesthesia
Surgery
Flap Ischemia
Flap Necrosis
Flap Failure Risk Factors
Microsurgery

Interventions

DRUG

No Results Yet

NCT06991114 | RECRUITING | PHASE2

90 participants

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-07-09
Completion:: 2028-01-31

Conditions

Refractory Rheumatoid Arthritis (RA)
Idiopathic Inflammatory Myopathies (IIMs)
Systemic Sclerosis (SSc)
Rheumatoid Arthritis (RA
IIM
Myositis
Scleroderma
Sjogren Syndrome
Sjogrens Disease

Interventions

DRUG

No Results Yet